4OLCA

Carbamate kinase from giardia lamblia thiocarbamoylated by disulfiram on cys242
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
315
structure length
308
Chain Sequence
SAGKTVVIALGGNAMLQAKEKGDYDTQRKNVEIAASEIYKIHKAGYKVVLTSGNGPQVGAIKLQNQAAAGVSPEMPLHVCGAMSQGFIGYMMSQAMDNVFCANNEPANCVTCVTQTLVDPKDQAFTNPTKPVGRFYTEQEAKDLMAANPGKILREDAGRGWRVVVPSPRPLEIVEYGVIKTLIDNNVLVICTNGGGIPCKRENKVISGVDAVIDKDLATSLLAKTLNSDYLMILTDVLNACIRKLEEIKLSEILALEKDGHFAAGSMGPKVRAAIEFTQATGKMSIITSLSTAVDALNGKCGTRIIKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Carbamate kinase
publication title Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
pubmed doi rcsb
source organism Giardia lamblia
molecule tags Transferase
total genus 100
structure length 308
sequence length 315
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.2: Carbamate kinase.
pdb deposition date 2014-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 4olcA00
2BNFA 3AB2A 2J4KA 1OHAA 4F6TA 2R98A 4OLCA 3NWYA 3QVHA 2X2WA 3QURA 2R8VA 3ZZFA 2E9YA 3KZFA 3QUOA 4NDOB 4NDQB 2A1FA 4NDPB 3TVIA 4JZ9A 2VA1A 2BUFA 4JZ8A 2J5TA 3K56A 1B7BA 3T7BA 3ZZGA 1Z9DA 3K52A 3LL9A 2BMUA 1OHBA 3ZZIA 2AP9A 3QUNA 1GS5A 4JZ7A 3C1NA 3S6GA 3ZZHA 2J5VA 3QVFA 2IJ9A 2WXBA 4KZTA 4Q1TA 4USJA 3LKKA 3D40A 2J0XA 3WWNA 2OGXB 4I49A 4F6TB 4AXSA 2CDQA 2V5HA 3L76A 2BNDA 2J4LA 3D2MA 2J0WA 2RD5A 3WWMA 2JJXA 3AAWA 2BTYA 3LL5A 3K4YA 2V4YA 3K4OA 4A7XA 3B8GA 2WE5A 2J4JA 3D41A 4NDRB 2W21A 2AKOA 1YBDA 1GSJA 2BRXA 2BRIA 4NDRA 3S6KA 1OH9A 3D2PA 3U6UA 3S6HA 2JJ4A 2WE4A 2HMFA 3EK6A 4NDOA 4NDQA 3EK5A 3C1MA 3C20A 4NDPA 2JI5A 4AB7A 1E19A 2BNEA 4A7WA 3AB4A 2OGXA 3L86A
chains in the Genus database with same CATH superfamily
2BNFA 3AB2A 2J4KA 1OHAA 4F6TA 2R98A 4OLCA 3NWYA 3QVHA 2X2WA 3QURA 2R8VA 3ZZFA 2E9YA 3KZFA 3QUOA 4NDOB 4NDQB 2A1FA 4NDPB 3TVIA 4JZ9A 2VA1A 2BUFA 4JZ8A 2J5TA 3K56A 1B7BA 3T7BA 3ZZGA 1Z9DA 3K52A 3LL9A 2BMUA 1OHBA 3ZZIA 2AP9A 3QUNA 1GS5A 4JZ7A 3C1NA 3S6GA 3ZZHA 2J5VA 3QVFA 2IJ9A 2WXBA 4KZTA 4Q1TA 4USJA 3LKKA 3D40A 2J0XA 3WWNA 2OGXB 4I49A 4F6TB 4AXSA 2CDQA 2V5HA 3L76A 2BNDA 2J4LA 3D2MA 2J0WA 2RD5A 3WWMA 2JJXA 3AAWA 2BTYA 3LL5A 3K4YA 2V4YA 3K4OA 4A7XA 3B8GA 2WE5A 2J4JA 3D41A 4NDRB 2W21A 2AKOA 1YBDA 1GSJA 2BRXA 2BRIA 4NDRA 3S6KA 1OH9A 3D2PA 3U6UA 3S6HA 2JJ4A 2WE4A 2HMFA 3EK6A 4NDOA 4NDQA 3EK5A 3C1MA 3C20A 4NDPA 2JI5A 4AB7A 1E19A 2BNEA 4A7WA 3AB4A 2OGXA 3L86A
chains in the Genus database with same CATH topology
2BNFA 3AB2A 2J4KA 1OHAA 4F6TA 2R98A 4OLCA 3NWYA 3QVHA 2X2WA 3QURA 2R8VA 3ZZFA 2E9YA 3KZFA 3QUOA 4NDOB 4NDQB 2A1FA 4NDPB 3TVIA 4JZ9A 2VA1A 2BUFA 4JZ8A 2J5TA 3K56A 1B7BA 3T7BA 3ZZGA 1Z9DA 3K52A 3LL9A 2BMUA 1OHBA 3ZZIA 2AP9A 3QUNA 1GS5A 4JZ7A 3C1NA 3S6GA 3ZZHA 2J5VA 3QVFA 2IJ9A 2WXBA 4KZTA 4Q1TA 4USJA 3LKKA 3D40A 2J0XA 3WWNA 2OGXB 4I49A 4F6TB 4AXSA 2CDQA 2V5HA 3L76A 2BNDA 2J4LA 3D2MA 2J0WA 2RD5A 3WWMA 2JJXA 3AAWA 2BTYA 3LL5A 3K4YA 2V4YA 3K4OA 4A7XA 3B8GA 2WE5A 2J4JA 3D41A 4NDRB 2W21A 2AKOA 1YBDA 1GSJA 2BRXA 2BRIA 4NDRA 3S6KA 1OH9A 3D2PA 3U6UA 3S6HA 2JJ4A 2WE4A 2HMFA 3EK6A 4NDOA 4NDQA 3EK5A 3C1MA 3C20A 4NDPA 2JI5A 4AB7A 1E19A 2BNEA 4A7WA 3AB4A 2OGXA 3L86A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BNF A;  3AB2 A;  2J4K A;  1OHA A;  4F6T A;  2R98 A;  4OLC A;  3NWY A;  3QVH A;  2X2W A;  3QUR A;  2R8V A;  3ZZF A;  2E9Y A;  3KZF A;  3QUO A;  4NDO B;  4NDQ B;  2A1F A;  4NDP B;  3TVI A;  4JZ9 A;  2VA1 A;  2BUF A;  4JZ8 A;  2J5T A;  3K56 A;  1B7B A;  3T7B A;  3ZZG A;  1Z9D A;  3K52 A;  3LL9 A;  2BMU A;  1OHB A;  3ZZI A;  2AP9 A;  3QUN A;  1GS5 A;  4JZ7 A;  3C1N A;  3S6G A;  3ZZH A;  2J5V A;  3QVF A;  2IJ9 A;  2WXB A;  4KZT A;  4Q1T A;  4USJ A;  3LKK A;  3D40 A;  2J0X A;  3WWN A;  2OGX B;  4I49 A;  4F6T B;  4AXS A;  2CDQ A;  2V5H A;  3L76 A;  2BND A;  2J4L A;  3D2M A;  2J0W A;  2RD5 A;  3WWM A;  2JJX A;  3AAW A;  2BTY A;  3LL5 A;  3K4Y A;  2V4Y A;  3K4O A;  4A7X A;  3B8G A;  2WE5 A;  2J4J A;  3D41 A;  4NDR B;  2W21 A;  2AKO A;  1YBD A;  1GSJ A;  2BRX A;  2BRI A;  4NDR A;  3S6K A;  1OH9 A;  3D2P A;  3U6U A;  3S6H A;  2JJ4 A;  2WE4 A;  2HMF A;  3EK6 A;  4NDO A;  4NDQ A;  3EK5 A;  3C1M A;  3C20 A;  4NDP A;  2JI5 A;  4AB7 A;  1E19 A;  2BNE A;  4A7W A;  3AB4 A;  2OGX A;  3L86 A; 
#chains in the Genus database with same CATH topology
 2BNF A;  3AB2 A;  2J4K A;  1OHA A;  4F6T A;  2R98 A;  4OLC A;  3NWY A;  3QVH A;  2X2W A;  3QUR A;  2R8V A;  3ZZF A;  2E9Y A;  3KZF A;  3QUO A;  4NDO B;  4NDQ B;  2A1F A;  4NDP B;  3TVI A;  4JZ9 A;  2VA1 A;  2BUF A;  4JZ8 A;  2J5T A;  3K56 A;  1B7B A;  3T7B A;  3ZZG A;  1Z9D A;  3K52 A;  3LL9 A;  2BMU A;  1OHB A;  3ZZI A;  2AP9 A;  3QUN A;  1GS5 A;  4JZ7 A;  3C1N A;  3S6G A;  3ZZH A;  2J5V A;  3QVF A;  2IJ9 A;  2WXB A;  4KZT A;  4Q1T A;  4USJ A;  3LKK A;  3D40 A;  2J0X A;  3WWN A;  2OGX B;  4I49 A;  4F6T B;  4AXS A;  2CDQ A;  2V5H A;  3L76 A;  2BND A;  2J4L A;  3D2M A;  2J0W A;  2RD5 A;  3WWM A;  2JJX A;  3AAW A;  2BTY A;  3LL5 A;  3K4Y A;  2V4Y A;  3K4O A;  4A7X A;  3B8G A;  2WE5 A;  2J4J A;  3D41 A;  4NDR B;  2W21 A;  2AKO A;  1YBD A;  1GSJ A;  2BRX A;  2BRI A;  4NDR A;  3S6K A;  1OH9 A;  3D2P A;  3U6U A;  3S6H A;  2JJ4 A;  2WE4 A;  2HMF A;  3EK6 A;  4NDO A;  4NDQ A;  3EK5 A;  3C1M A;  3C20 A;  4NDP A;  2JI5 A;  4AB7 A;  1E19 A;  2BNE A;  4A7W A;  3AB4 A;  2OGX A;  3L86 A; 
#chains in the Genus database with same CATH homology
 2BNF A;  3AB2 A;  2J4K A;  1OHA A;  4F6T A;  2R98 A;  4OLC A;  3NWY A;  3QVH A;  2X2W A;  3QUR A;  2R8V A;  3ZZF A;  2E9Y A;  3KZF A;  3QUO A;  4NDO B;  4NDQ B;  2A1F A;  4NDP B;  3TVI A;  4JZ9 A;  2VA1 A;  2BUF A;  4JZ8 A;  2J5T A;  3K56 A;  1B7B A;  3T7B A;  3ZZG A;  1Z9D A;  3K52 A;  3LL9 A;  2BMU A;  1OHB A;  3ZZI A;  2AP9 A;  3QUN A;  1GS5 A;  4JZ7 A;  3C1N A;  3S6G A;  3ZZH A;  2J5V A;  3QVF A;  2IJ9 A;  2WXB A;  4KZT A;  4Q1T A;  4USJ A;  3LKK A;  3D40 A;  2J0X A;  3WWN A;  2OGX B;  4I49 A;  4F6T B;  4AXS A;  2CDQ A;  2V5H A;  3L76 A;  2BND A;  2J4L A;  3D2M A;  2J0W A;  2RD5 A;  3WWM A;  2JJX A;  3AAW A;  2BTY A;  3LL5 A;  3K4Y A;  2V4Y A;  3K4O A;  4A7X A;  3B8G A;  2WE5 A;  2J4J A;  3D41 A;  4NDR B;  2W21 A;  2AKO A;  1YBD A;  1GSJ A;  2BRX A;  2BRI A;  4NDR A;  3S6K A;  1OH9 A;  3D2P A;  3U6U A;  3S6H A;  2JJ4 A;  2WE4 A;  2HMF A;  3EK6 A;  4NDO A;  4NDQ A;  3EK5 A;  3C1M A;  3C20 A;  4NDP A;  2JI5 A;  4AB7 A;  1E19 A;  2BNE A;  4A7W A;  3AB4 A;  2OGX A;  3L86 A; 
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similar chains in the Genus database (?% sequence similarity)
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