4OLCA

Carbamate kinase from giardia lamblia thiocarbamoylated by disulfiram on cys242
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
315
structure length
308
Chain Sequence
b'SAGKTVVIALGGNAMLQAKEKGDYDTQRKNVEIAASEIYKIHKAGYKVVLTSGNGPQVGAIKLQNQAAAGVSPEMPLHVCGAMSQGFIGYMMSQAMDNVFCANNEPANCVTCVTQTLVDPKDQAFTNPTKPVGRFYTEQEAKDLMAANPGKILREDAGRGWRVVVPSPRPLEIVEYGVIKTLIDNNVLVICTNGGGIPCKRENKVISGVDAVIDKDLATSLLAKTLNSDYLMILTDVLNACIRKLEEIKLSEILALEKDGHFAAGSMGPKVRAAIEFTQATGKMSIITSLSTAVDALNGKCGTRIIKD'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Carbamate kinase
publication title Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
pubmed doi rcsb
source organism Giardia lamblia
molecule tags Transferase
total genus 100
structure length 308
sequence length 315
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.2: Carbamate kinase.
pdb deposition date 2014-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 4olcA00
2BUFA 2CDQA 3LL5A 4KZTA 3U6UA 2J4KA 3EK6A 3L76A 3ZZIA 3NWYA 2W21A 4F6TA 2X2WA 2VA1A 3C20A 4F6TB 3QVHA 3QUNA 2R98A 2AKOA 1OHBA 4JZ8A 2V4YA 3K4OA 4NDQB 3AB2A 2J5VA 4AB7A 1YBDA 3D2PA 2HMFA 2E9YA 3WWNA 2RD5A 3B8GA 3D41A 2J4LA 4NDRB 2JI5A 2BMUA 2WXBA 3AAWA 4NDQA 2BTYA 2J0WA 3TVIA 3ZZFA 1Z9DA 4I49A 3QUOA 3K4YA 3LKKA 2WE4A 3KZFA 2BRXA 2OGXA 3S6GA 4A7XA 3ZZHA 2OGXB 4NDPA 4NDRA 2BNEA 3LL9A 3K56A 3D2MA 4JZ7A 3K52A 3S6HA 3WWMA 4NDPB 2R8VA 2J4JA 3ZZGA 2J5TA 4AXSA 1OH9A 4OLCA 3L86A 2IJ9A 1B7BA 3T7BA 3QURA 1OHAA 2V5HA 2BNDA 3D40A 3C1MA 4NDOA 1E19A 2AP9A 2JJXA 4NDOB 2BNFA 1GSJA 3QVFA 3S6KA 1GS5A 3AB4A 2A1FA 3EK5A 3C1NA 4USJA 4JZ9A 2BRIA 4Q1TA 2WE5A 4A7WA 2J0XA 2JJ4A
chains in the Genus database with same CATH superfamily
2BUFA 2CDQA 3LL5A 4KZTA 3U6UA 2J4KA 3EK6A 3L76A 3ZZIA 3NWYA 2W21A 4F6TA 2X2WA 2VA1A 3C20A 4F6TB 3QVHA 3QUNA 2R98A 2AKOA 1OHBA 4JZ8A 2V4YA 3K4OA 4NDQB 3AB2A 2J5VA 4AB7A 1YBDA 3D2PA 2HMFA 2E9YA 3WWNA 2RD5A 3B8GA 3D41A 2J4LA 4NDRB 2JI5A 2BMUA 2WXBA 3AAWA 4NDQA 2BTYA 2J0WA 3TVIA 3ZZFA 1Z9DA 4I49A 3QUOA 3K4YA 3LKKA 2WE4A 3KZFA 2BRXA 2OGXA 3S6GA 4A7XA 3ZZHA 2OGXB 4NDPA 4NDRA 2BNEA 3LL9A 3K56A 3D2MA 4JZ7A 3K52A 3S6HA 3WWMA 4NDPB 2R8VA 2J4JA 3ZZGA 2J5TA 4AXSA 1OH9A 4OLCA 3L86A 2IJ9A 1B7BA 3T7BA 3QURA 1OHAA 2V5HA 2BNDA 3D40A 3C1MA 4NDOA 1E19A 2AP9A 2JJXA 4NDOB 2BNFA 1GSJA 3QVFA 3S6KA 1GS5A 3AB4A 2A1FA 3EK5A 3C1NA 4USJA 4JZ9A 2BRIA 4Q1TA 2WE5A 4A7WA 2J0XA 2JJ4A
chains in the Genus database with same CATH topology
2BUFA 2CDQA 3LL5A 4KZTA 3U6UA 2J4KA 3EK6A 3L76A 3ZZIA 3NWYA 2W21A 4F6TA 2X2WA 2VA1A 3C20A 4F6TB 3QVHA 3QUNA 2R98A 2AKOA 1OHBA 4JZ8A 2V4YA 3K4OA 4NDQB 3AB2A 2J5VA 4AB7A 1YBDA 3D2PA 2HMFA 2E9YA 3WWNA 2RD5A 3B8GA 3D41A 2J4LA 4NDRB 2JI5A 2BMUA 2WXBA 3AAWA 4NDQA 2BTYA 2J0WA 3TVIA 3ZZFA 1Z9DA 4I49A 3QUOA 3K4YA 3LKKA 2WE4A 3KZFA 2BRXA 2OGXA 3S6GA 4A7XA 3ZZHA 2OGXB 4NDPA 4NDRA 2BNEA 3LL9A 3K56A 3D2MA 4JZ7A 3K52A 3S6HA 3WWMA 4NDPB 2R8VA 2J4JA 3ZZGA 2J5TA 4AXSA 1OH9A 4OLCA 3L86A 2IJ9A 1B7BA 3T7BA 3QURA 1OHAA 2V5HA 2BNDA 3D40A 3C1MA 4NDOA 1E19A 2AP9A 2JJXA 4NDOB 2BNFA 1GSJA 3QVFA 3S6KA 1GS5A 3AB4A 2A1FA 3EK5A 3C1NA 4USJA 4JZ9A 2BRIA 4Q1TA 2WE5A 4A7WA 2J0XA 2JJ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BUF A;  2CDQ A;  3LL5 A;  4KZT A;  3U6U A;  2J4K A;  3EK6 A;  3L76 A;  3ZZI A;  3NWY A;  2W21 A;  4F6T A;  2X2W A;  2VA1 A;  3C20 A;  4F6T B;  3QVH A;  3QUN A;  2R98 A;  2AKO A;  1OHB A;  4JZ8 A;  2V4Y A;  3K4O A;  4NDQ B;  3AB2 A;  2J5V A;  4AB7 A;  1YBD A;  3D2P A;  2HMF A;  2E9Y A;  3WWN A;  2RD5 A;  3B8G A;  3D41 A;  2J4L A;  4NDR B;  2JI5 A;  2BMU A;  2WXB A;  3AAW A;  4NDQ A;  2BTY A;  2J0W A;  3TVI A;  3ZZF A;  1Z9D A;  4I49 A;  3QUO A;  3K4Y A;  3LKK A;  2WE4 A;  3KZF A;  2BRX A;  2OGX A;  3S6G A;  4A7X A;  3ZZH A;  2OGX B;  4NDP A;  4NDR A;  2BNE A;  3LL9 A;  3K56 A;  3D2M A;  4JZ7 A;  3K52 A;  3S6H A;  3WWM A;  4NDP B;  2R8V A;  2J4J A;  3ZZG A;  2J5T A;  4AXS A;  1OH9 A;  4OLC A;  3L86 A;  2IJ9 A;  1B7B A;  3T7B A;  3QUR A;  1OHA A;  2V5H A;  2BND A;  3D40 A;  3C1M A;  4NDO A;  1E19 A;  2AP9 A;  2JJX A;  4NDO B;  2BNF A;  1GSJ A;  3QVF A;  3S6K A;  1GS5 A;  3AB4 A;  2A1F A;  3EK5 A;  3C1N A;  4USJ A;  4JZ9 A;  2BRI A;  4Q1T A;  2WE5 A;  4A7W A;  2J0X A;  2JJ4 A; 
#chains in the Genus database with same CATH topology
 2BUF A;  2CDQ A;  3LL5 A;  4KZT A;  3U6U A;  2J4K A;  3EK6 A;  3L76 A;  3ZZI A;  3NWY A;  2W21 A;  4F6T A;  2X2W A;  2VA1 A;  3C20 A;  4F6T B;  3QVH A;  3QUN A;  2R98 A;  2AKO A;  1OHB A;  4JZ8 A;  2V4Y A;  3K4O A;  4NDQ B;  3AB2 A;  2J5V A;  4AB7 A;  1YBD A;  3D2P A;  2HMF A;  2E9Y A;  3WWN A;  2RD5 A;  3B8G A;  3D41 A;  2J4L A;  4NDR B;  2JI5 A;  2BMU A;  2WXB A;  3AAW A;  4NDQ A;  2BTY A;  2J0W A;  3TVI A;  3ZZF A;  1Z9D A;  4I49 A;  3QUO A;  3K4Y A;  3LKK A;  2WE4 A;  3KZF A;  2BRX A;  2OGX A;  3S6G A;  4A7X A;  3ZZH A;  2OGX B;  4NDP A;  4NDR A;  2BNE A;  3LL9 A;  3K56 A;  3D2M A;  4JZ7 A;  3K52 A;  3S6H A;  3WWM A;  4NDP B;  2R8V A;  2J4J A;  3ZZG A;  2J5T A;  4AXS A;  1OH9 A;  4OLC A;  3L86 A;  2IJ9 A;  1B7B A;  3T7B A;  3QUR A;  1OHA A;  2V5H A;  2BND A;  3D40 A;  3C1M A;  4NDO A;  1E19 A;  2AP9 A;  2JJX A;  4NDO B;  2BNF A;  1GSJ A;  3QVF A;  3S6K A;  1GS5 A;  3AB4 A;  2A1F A;  3EK5 A;  3C1N A;  4USJ A;  4JZ9 A;  2BRI A;  4Q1T A;  2WE5 A;  4A7W A;  2J0X A;  2JJ4 A; 
#chains in the Genus database with same CATH homology
 2BUF A;  2CDQ A;  3LL5 A;  4KZT A;  3U6U A;  2J4K A;  3EK6 A;  3L76 A;  3ZZI A;  3NWY A;  2W21 A;  4F6T A;  2X2W A;  2VA1 A;  3C20 A;  4F6T B;  3QVH A;  3QUN A;  2R98 A;  2AKO A;  1OHB A;  4JZ8 A;  2V4Y A;  3K4O A;  4NDQ B;  3AB2 A;  2J5V A;  4AB7 A;  1YBD A;  3D2P A;  2HMF A;  2E9Y A;  3WWN A;  2RD5 A;  3B8G A;  3D41 A;  2J4L A;  4NDR B;  2JI5 A;  2BMU A;  2WXB A;  3AAW A;  4NDQ A;  2BTY A;  2J0W A;  3TVI A;  3ZZF A;  1Z9D A;  4I49 A;  3QUO A;  3K4Y A;  3LKK A;  2WE4 A;  3KZF A;  2BRX A;  2OGX A;  3S6G A;  4A7X A;  3ZZH A;  2OGX B;  4NDP A;  4NDR A;  2BNE A;  3LL9 A;  3K56 A;  3D2M A;  4JZ7 A;  3K52 A;  3S6H A;  3WWM A;  4NDP B;  2R8V A;  2J4J A;  3ZZG A;  2J5T A;  4AXS A;  1OH9 A;  4OLC A;  3L86 A;  2IJ9 A;  1B7B A;  3T7B A;  3QUR A;  1OHA A;  2V5H A;  2BND A;  3D40 A;  3C1M A;  4NDO A;  1E19 A;  2AP9 A;  2JJX A;  4NDO B;  2BNF A;  1GSJ A;  3QVF A;  3S6K A;  1GS5 A;  3AB4 A;  2A1F A;  3EK5 A;  3C1N A;  4USJ A;  4JZ9 A;  2BRI A;  4Q1T A;  2WE5 A;  4A7W A;  2J0X A;  2JJ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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