4OLCA

Carbamate kinase from giardia lamblia thiocarbamoylated by disulfiram on cys242
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
315
structure length
308
Chain Sequence
SAGKTVVIALGGNAMLQAKEKGDYDTQRKNVEIAASEIYKIHKAGYKVVLTSGNGPQVGAIKLQNQAAAGVSPEMPLHVCGAMSQGFIGYMMSQAMDNVFCANNEPANCVTCVTQTLVDPKDQAFTNPTKPVGRFYTEQEAKDLMAANPGKILREDAGRGWRVVVPSPRPLEIVEYGVIKTLIDNNVLVICTNGGGIPCKRENKVISGVDAVIDKDLATSLLAKTLNSDYLMILTDVLNACIRKLEEIKLSEILALEKDGHFAAGSMGPKVRAAIEFTQATGKMSIITSLSTAVDALNGKCGTRIIKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Carbamate kinase
publication title Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
pubmed doi rcsb
source organism Giardia lamblia
total genus 100
structure length 308
sequence length 315
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.2: Carbamate kinase.
pdb deposition date 2014-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 4olcA00
4NDQB 2E9YA 4NDOB 4F6TA 3C1MA 2J5VA 3S6GA 4OLCA 1GS5A 4F6TB 3NWYA 3L86A 4NDPA 2BNFA 2V5HA 3KZFA 4NDPB 2JI5A 3ZZFA 2A1FA 3ZZGA 2R98A 3AB2A 2BTYA 2J4KA 2J0XA 2W21A 2AKOA 3ZZIA 2BRIA 3C1NA 4JZ8A 1E19A 3K52A 2WE5A 2OGXB 3TVIA 3U6UA 3D40A 2BRXA 3B8GA 3QURA 4NDRA 3D2PA 3D41A 3AAWA 2R8VA 3QUNA 3LL5A 2WXBA 2J5TA 4A7WA 2AP9A 4KZTA 1OHBA 2WE4A 3AB4A 4Q1TA 2CDQA 3LL9A 1GSJA 2J4JA 3K4YA 3LKKA 4AXSA 3T7BA 4JZ9A 1Z9DA 2BUFA 3QVFA 3EK5A 3QVHA 2JJ4A 3K4OA 2OGXA 2BNDA 4NDRB 1OH9A 2X2WA 4AB7A 4JZ7A 2J4LA 3L76A 4NDQA 4USJA 4NDOA 2BMUA 3ZZHA 1B7BA 3K56A 1OHAA 2BNEA 2HMFA 2J0WA 4A7XA 3S6KA 3WWNA 3S6HA 4I49A 3D2MA 2IJ9A 3QUOA 2JJXA 1YBDA 2V4YA 2VA1A 3EK6A 3WWMA 2RD5A 3C20A
chains in the Genus database with same CATH superfamily
4NDQB 2E9YA 4NDOB 4F6TA 3C1MA 2J5VA 3S6GA 4OLCA 1GS5A 4F6TB 3NWYA 3L86A 4NDPA 2BNFA 2V5HA 3KZFA 4NDPB 2JI5A 3ZZFA 2A1FA 3ZZGA 2R98A 3AB2A 2BTYA 2J4KA 2J0XA 2W21A 2AKOA 3ZZIA 2BRIA 3C1NA 4JZ8A 1E19A 3K52A 2WE5A 2OGXB 3TVIA 3U6UA 3D40A 2BRXA 3B8GA 3QURA 4NDRA 3D2PA 3D41A 3AAWA 2R8VA 3QUNA 3LL5A 2WXBA 2J5TA 4A7WA 2AP9A 4KZTA 1OHBA 2WE4A 3AB4A 4Q1TA 2CDQA 3LL9A 1GSJA 2J4JA 3K4YA 3LKKA 4AXSA 3T7BA 4JZ9A 1Z9DA 2BUFA 3QVFA 3EK5A 3QVHA 2JJ4A 3K4OA 2OGXA 2BNDA 4NDRB 1OH9A 2X2WA 4AB7A 4JZ7A 2J4LA 3L76A 4NDQA 4USJA 4NDOA 2BMUA 3ZZHA 1B7BA 3K56A 1OHAA 2BNEA 2HMFA 2J0WA 4A7XA 3S6KA 3WWNA 3S6HA 4I49A 3D2MA 2IJ9A 3QUOA 2JJXA 1YBDA 2V4YA 2VA1A 3EK6A 3WWMA 2RD5A 3C20A
chains in the Genus database with same CATH topology
4NDQB 2E9YA 4NDOB 4F6TA 3C1MA 2J5VA 3S6GA 4OLCA 1GS5A 4F6TB 3NWYA 3L86A 4NDPA 2BNFA 2V5HA 3KZFA 4NDPB 2JI5A 3ZZFA 2A1FA 3ZZGA 2R98A 3AB2A 2BTYA 2J4KA 2J0XA 2W21A 2AKOA 3ZZIA 2BRIA 3C1NA 4JZ8A 1E19A 3K52A 2WE5A 2OGXB 3TVIA 3U6UA 3D40A 2BRXA 3B8GA 3QURA 4NDRA 3D2PA 3D41A 3AAWA 2R8VA 3QUNA 3LL5A 2WXBA 2J5TA 4A7WA 2AP9A 4KZTA 1OHBA 2WE4A 3AB4A 4Q1TA 2CDQA 3LL9A 1GSJA 2J4JA 3K4YA 3LKKA 4AXSA 3T7BA 4JZ9A 1Z9DA 2BUFA 3QVFA 3EK5A 3QVHA 2JJ4A 3K4OA 2OGXA 2BNDA 4NDRB 1OH9A 2X2WA 4AB7A 4JZ7A 2J4LA 3L76A 4NDQA 4USJA 4NDOA 2BMUA 3ZZHA 1B7BA 3K56A 1OHAA 2BNEA 2HMFA 2J0WA 4A7XA 3S6KA 3WWNA 3S6HA 4I49A 3D2MA 2IJ9A 3QUOA 2JJXA 1YBDA 2V4YA 2VA1A 3EK6A 3WWMA 2RD5A 3C20A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NDQ B;  2E9Y A;  4NDO B;  4F6T A;  3C1M A;  2J5V A;  3S6G A;  4OLC A;  1GS5 A;  4F6T B;  3NWY A;  3L86 A;  4NDP A;  2BNF A;  2V5H A;  3KZF A;  4NDP B;  2JI5 A;  3ZZF A;  2A1F A;  3ZZG A;  2R98 A;  3AB2 A;  2BTY A;  2J4K A;  2J0X A;  2W21 A;  2AKO A;  3ZZI A;  2BRI A;  3C1N A;  4JZ8 A;  1E19 A;  3K52 A;  2WE5 A;  2OGX B;  3TVI A;  3U6U A;  3D40 A;  2BRX A;  3B8G A;  3QUR A;  4NDR A;  3D2P A;  3D41 A;  3AAW A;  2R8V A;  3QUN A;  3LL5 A;  2WXB A;  2J5T A;  4A7W A;  2AP9 A;  4KZT A;  1OHB A;  2WE4 A;  3AB4 A;  4Q1T A;  2CDQ A;  3LL9 A;  1GSJ A;  2J4J A;  3K4Y A;  3LKK A;  4AXS A;  3T7B A;  4JZ9 A;  1Z9D A;  2BUF A;  3QVF A;  3EK5 A;  3QVH A;  2JJ4 A;  3K4O A;  2OGX A;  2BND A;  4NDR B;  1OH9 A;  2X2W A;  4AB7 A;  4JZ7 A;  2J4L A;  3L76 A;  4NDQ A;  4USJ A;  4NDO A;  2BMU A;  3ZZH A;  1B7B A;  3K56 A;  1OHA A;  2BNE A;  2HMF A;  2J0W A;  4A7X A;  3S6K A;  3WWN A;  3S6H A;  4I49 A;  3D2M A;  2IJ9 A;  3QUO A;  2JJX A;  1YBD A;  2V4Y A;  2VA1 A;  3EK6 A;  3WWM A;  2RD5 A;  3C20 A; 
#chains in the Genus database with same CATH topology
 4NDQ B;  2E9Y A;  4NDO B;  4F6T A;  3C1M A;  2J5V A;  3S6G A;  4OLC A;  1GS5 A;  4F6T B;  3NWY A;  3L86 A;  4NDP A;  2BNF A;  2V5H A;  3KZF A;  4NDP B;  2JI5 A;  3ZZF A;  2A1F A;  3ZZG A;  2R98 A;  3AB2 A;  2BTY A;  2J4K A;  2J0X A;  2W21 A;  2AKO A;  3ZZI A;  2BRI A;  3C1N A;  4JZ8 A;  1E19 A;  3K52 A;  2WE5 A;  2OGX B;  3TVI A;  3U6U A;  3D40 A;  2BRX A;  3B8G A;  3QUR A;  4NDR A;  3D2P A;  3D41 A;  3AAW A;  2R8V A;  3QUN A;  3LL5 A;  2WXB A;  2J5T A;  4A7W A;  2AP9 A;  4KZT A;  1OHB A;  2WE4 A;  3AB4 A;  4Q1T A;  2CDQ A;  3LL9 A;  1GSJ A;  2J4J A;  3K4Y A;  3LKK A;  4AXS A;  3T7B A;  4JZ9 A;  1Z9D A;  2BUF A;  3QVF A;  3EK5 A;  3QVH A;  2JJ4 A;  3K4O A;  2OGX A;  2BND A;  4NDR B;  1OH9 A;  2X2W A;  4AB7 A;  4JZ7 A;  2J4L A;  3L76 A;  4NDQ A;  4USJ A;  4NDO A;  2BMU A;  3ZZH A;  1B7B A;  3K56 A;  1OHA A;  2BNE A;  2HMF A;  2J0W A;  4A7X A;  3S6K A;  3WWN A;  3S6H A;  4I49 A;  3D2M A;  2IJ9 A;  3QUO A;  2JJX A;  1YBD A;  2V4Y A;  2VA1 A;  3EK6 A;  3WWM A;  2RD5 A;  3C20 A; 
#chains in the Genus database with same CATH homology
 4NDQ B;  2E9Y A;  4NDO B;  4F6T A;  3C1M A;  2J5V A;  3S6G A;  4OLC A;  1GS5 A;  4F6T B;  3NWY A;  3L86 A;  4NDP A;  2BNF A;  2V5H A;  3KZF A;  4NDP B;  2JI5 A;  3ZZF A;  2A1F A;  3ZZG A;  2R98 A;  3AB2 A;  2BTY A;  2J4K A;  2J0X A;  2W21 A;  2AKO A;  3ZZI A;  2BRI A;  3C1N A;  4JZ8 A;  1E19 A;  3K52 A;  2WE5 A;  2OGX B;  3TVI A;  3U6U A;  3D40 A;  2BRX A;  3B8G A;  3QUR A;  4NDR A;  3D2P A;  3D41 A;  3AAW A;  2R8V A;  3QUN A;  3LL5 A;  2WXB A;  2J5T A;  4A7W A;  2AP9 A;  4KZT A;  1OHB A;  2WE4 A;  3AB4 A;  4Q1T A;  2CDQ A;  3LL9 A;  1GSJ A;  2J4J A;  3K4Y A;  3LKK A;  4AXS A;  3T7B A;  4JZ9 A;  1Z9D A;  2BUF A;  3QVF A;  3EK5 A;  3QVH A;  2JJ4 A;  3K4O A;  2OGX A;  2BND A;  4NDR B;  1OH9 A;  2X2W A;  4AB7 A;  4JZ7 A;  2J4L A;  3L76 A;  4NDQ A;  4USJ A;  4NDO A;  2BMU A;  3ZZH A;  1B7B A;  3K56 A;  1OHA A;  2BNE A;  2HMF A;  2J0W A;  4A7X A;  3S6K A;  3WWN A;  3S6H A;  4I49 A;  3D2M A;  2IJ9 A;  3QUO A;  2JJX A;  1YBD A;  2V4Y A;  2VA1 A;  3EK6 A;  3WWM A;  2RD5 A;  3C20 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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