2J4JA

Crystal structure of uridylate kinase from sulfolobus solfataricus in complex with ump and amppcp to 2.1 angstrom resolution
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
226
structure length
216
Chain Sequence
MNIILKISGKFFDEDNVDNLIVLRQSIKELADNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRIYADVKLIPHLTTQDLRKILEELLDPLAIKIVERSKIRVIVMNYRKLNRIIDILKGEEVSSIIEPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Transferase
molecule keywords URIDYLATE KINASE
total genus 76
structure length 216
sequence length 226
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2006-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j4jA00
2BNEA 3QUNA 2J4JA 3EK5A 1YBDA 3AAWA 2W21A 3C1NA 3EK6A 2RD5A 3ZZHA 2AKOA 3D2MA 4JZ7A 2JJ4A 4NDPA 4AB7A 2J5TA 1OHAA 1E19A 4F6TB 3KZFA 3QVFA 2BRXA 3L86A 3C20A 2BMUA 1B7BA 4NDPB 3NWYA 2JJXA 3B8GA 3D41A 3TVIA 2BRIA 2OGXA 4F6TA 1OH9A 2E9YA 3LL5A 3AB4A 3LKKA 3QURA 3D2PA 3K52A 4NDQA 2BTYA 3U6UA 2X2WA 3ZZFA 2BNDA 2WE5A 3AB2A 3K4YA 3WWNA 1Z9DA 4JZ8A 2OGXB 3T7BA 2AP9A 2WE4A 3L76A 4OLCA 4NDRB 2WXBA 3S6HA 3QVHA 3K4OA 3ZZGA 4NDQB 2JI5A 2J5VA 4NDOB 4A7XA 3C1MA 3WWMA 3S6GA 2J0WA 4AXSA 3LL9A 2V5HA 2BNFA 2VA1A 3K56A 4Q1TA 4JZ9A 4NDRA 3S6KA 2J4KA 2HMFA 2V4YA 3D40A 4USJA 4A7WA 4I49A 2A1FA 2J4LA 3QUOA 1GS5A 2BUFA 2J0XA 2R98A 2CDQA 2IJ9A 4KZTA 2R8VA 1OHBA 3ZZIA 4NDOA 1GSJA
chains in the Genus database with same CATH superfamily
2BNEA 3QUNA 2J4JA 3EK5A 1YBDA 3AAWA 2W21A 3C1NA 3EK6A 2RD5A 3ZZHA 2AKOA 3D2MA 4JZ7A 2JJ4A 4NDPA 4AB7A 2J5TA 1OHAA 1E19A 4F6TB 3KZFA 3QVFA 2BRXA 3L86A 3C20A 2BMUA 1B7BA 4NDPB 3NWYA 2JJXA 3B8GA 3D41A 3TVIA 2BRIA 2OGXA 4F6TA 1OH9A 2E9YA 3LL5A 3AB4A 3LKKA 3QURA 3D2PA 3K52A 4NDQA 2BTYA 3U6UA 2X2WA 3ZZFA 2BNDA 2WE5A 3AB2A 3K4YA 3WWNA 1Z9DA 4JZ8A 2OGXB 3T7BA 2AP9A 2WE4A 3L76A 4OLCA 4NDRB 2WXBA 3S6HA 3QVHA 3K4OA 3ZZGA 4NDQB 2JI5A 2J5VA 4NDOB 4A7XA 3C1MA 3WWMA 3S6GA 2J0WA 4AXSA 3LL9A 2V5HA 2BNFA 2VA1A 3K56A 4Q1TA 4JZ9A 4NDRA 3S6KA 2J4KA 2HMFA 2V4YA 3D40A 4USJA 4A7WA 4I49A 2A1FA 2J4LA 3QUOA 1GS5A 2BUFA 2J0XA 2R98A 2CDQA 2IJ9A 4KZTA 2R8VA 1OHBA 3ZZIA 4NDOA 1GSJA
chains in the Genus database with same CATH topology
2BNEA 3QUNA 2J4JA 3EK5A 1YBDA 3AAWA 2W21A 3C1NA 3EK6A 2RD5A 3ZZHA 2AKOA 3D2MA 4JZ7A 2JJ4A 4NDPA 4AB7A 2J5TA 1OHAA 1E19A 4F6TB 3KZFA 3QVFA 2BRXA 3L86A 3C20A 2BMUA 1B7BA 4NDPB 3NWYA 2JJXA 3B8GA 3D41A 3TVIA 2BRIA 2OGXA 4F6TA 1OH9A 2E9YA 3LL5A 3AB4A 3LKKA 3QURA 3D2PA 3K52A 4NDQA 2BTYA 3U6UA 2X2WA 3ZZFA 2BNDA 2WE5A 3AB2A 3K4YA 3WWNA 1Z9DA 4JZ8A 2OGXB 3T7BA 2AP9A 2WE4A 3L76A 4OLCA 4NDRB 2WXBA 3S6HA 3QVHA 3K4OA 3ZZGA 4NDQB 2JI5A 2J5VA 4NDOB 4A7XA 3C1MA 3WWMA 3S6GA 2J0WA 4AXSA 3LL9A 2V5HA 2BNFA 2VA1A 3K56A 4Q1TA 4JZ9A 4NDRA 3S6KA 2J4KA 2HMFA 2V4YA 3D40A 4USJA 4A7WA 4I49A 2A1FA 2J4LA 3QUOA 1GS5A 2BUFA 2J0XA 2R98A 2CDQA 2IJ9A 4KZTA 2R8VA 1OHBA 3ZZIA 4NDOA 1GSJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BNE A;  3QUN A;  2J4J A;  3EK5 A;  1YBD A;  3AAW A;  2W21 A;  3C1N A;  3EK6 A;  2RD5 A;  3ZZH A;  2AKO A;  3D2M A;  4JZ7 A;  2JJ4 A;  4NDP A;  4AB7 A;  2J5T A;  1OHA A;  1E19 A;  4F6T B;  3KZF A;  3QVF A;  2BRX A;  3L86 A;  3C20 A;  2BMU A;  1B7B A;  4NDP B;  3NWY A;  2JJX A;  3B8G A;  3D41 A;  3TVI A;  2BRI A;  2OGX A;  4F6T A;  1OH9 A;  2E9Y A;  3LL5 A;  3AB4 A;  3LKK A;  3QUR A;  3D2P A;  3K52 A;  4NDQ A;  2BTY A;  3U6U A;  2X2W A;  3ZZF A;  2BND A;  2WE5 A;  3AB2 A;  3K4Y A;  3WWN A;  1Z9D A;  4JZ8 A;  2OGX B;  3T7B A;  2AP9 A;  2WE4 A;  3L76 A;  4OLC A;  4NDR B;  2WXB A;  3S6H A;  3QVH A;  3K4O A;  3ZZG A;  4NDQ B;  2JI5 A;  2J5V A;  4NDO B;  4A7X A;  3C1M A;  3WWM A;  3S6G A;  2J0W A;  4AXS A;  3LL9 A;  2V5H A;  2BNF A;  2VA1 A;  3K56 A;  4Q1T A;  4JZ9 A;  4NDR A;  3S6K A;  2J4K A;  2HMF A;  2V4Y A;  3D40 A;  4USJ A;  4A7W A;  4I49 A;  2A1F A;  2J4L A;  3QUO A;  1GS5 A;  2BUF A;  2J0X A;  2R98 A;  2CDQ A;  2IJ9 A;  4KZT A;  2R8V A;  1OHB A;  3ZZI A;  4NDO A;  1GSJ A; 
#chains in the Genus database with same CATH topology
 2BNE A;  3QUN A;  2J4J A;  3EK5 A;  1YBD A;  3AAW A;  2W21 A;  3C1N A;  3EK6 A;  2RD5 A;  3ZZH A;  2AKO A;  3D2M A;  4JZ7 A;  2JJ4 A;  4NDP A;  4AB7 A;  2J5T A;  1OHA A;  1E19 A;  4F6T B;  3KZF A;  3QVF A;  2BRX A;  3L86 A;  3C20 A;  2BMU A;  1B7B A;  4NDP B;  3NWY A;  2JJX A;  3B8G A;  3D41 A;  3TVI A;  2BRI A;  2OGX A;  4F6T A;  1OH9 A;  2E9Y A;  3LL5 A;  3AB4 A;  3LKK A;  3QUR A;  3D2P A;  3K52 A;  4NDQ A;  2BTY A;  3U6U A;  2X2W A;  3ZZF A;  2BND A;  2WE5 A;  3AB2 A;  3K4Y A;  3WWN A;  1Z9D A;  4JZ8 A;  2OGX B;  3T7B A;  2AP9 A;  2WE4 A;  3L76 A;  4OLC A;  4NDR B;  2WXB A;  3S6H A;  3QVH A;  3K4O A;  3ZZG A;  4NDQ B;  2JI5 A;  2J5V A;  4NDO B;  4A7X A;  3C1M A;  3WWM A;  3S6G A;  2J0W A;  4AXS A;  3LL9 A;  2V5H A;  2BNF A;  2VA1 A;  3K56 A;  4Q1T A;  4JZ9 A;  4NDR A;  3S6K A;  2J4K A;  2HMF A;  2V4Y A;  3D40 A;  4USJ A;  4A7W A;  4I49 A;  2A1F A;  2J4L A;  3QUO A;  1GS5 A;  2BUF A;  2J0X A;  2R98 A;  2CDQ A;  2IJ9 A;  4KZT A;  2R8V A;  1OHB A;  3ZZI A;  4NDO A;  1GSJ A; 
#chains in the Genus database with same CATH homology
 2BNE A;  3QUN A;  2J4J A;  3EK5 A;  1YBD A;  3AAW A;  2W21 A;  3C1N A;  3EK6 A;  2RD5 A;  3ZZH A;  2AKO A;  3D2M A;  4JZ7 A;  2JJ4 A;  4NDP A;  4AB7 A;  2J5T A;  1OHA A;  1E19 A;  4F6T B;  3KZF A;  3QVF A;  2BRX A;  3L86 A;  3C20 A;  2BMU A;  1B7B A;  4NDP B;  3NWY A;  2JJX A;  3B8G A;  3D41 A;  3TVI A;  2BRI A;  2OGX A;  4F6T A;  1OH9 A;  2E9Y A;  3LL5 A;  3AB4 A;  3LKK A;  3QUR A;  3D2P A;  3K52 A;  4NDQ A;  2BTY A;  3U6U A;  2X2W A;  3ZZF A;  2BND A;  2WE5 A;  3AB2 A;  3K4Y A;  3WWN A;  1Z9D A;  4JZ8 A;  2OGX B;  3T7B A;  2AP9 A;  2WE4 A;  3L76 A;  4OLC A;  4NDR B;  2WXB A;  3S6H A;  3QVH A;  3K4O A;  3ZZG A;  4NDQ B;  2JI5 A;  2J5V A;  4NDO B;  4A7X A;  3C1M A;  3WWM A;  3S6G A;  2J0W A;  4AXS A;  3LL9 A;  2V5H A;  2BNF A;  2VA1 A;  3K56 A;  4Q1T A;  4JZ9 A;  4NDR A;  3S6K A;  2J4K A;  2HMF A;  2V4Y A;  3D40 A;  4USJ A;  4A7W A;  4I49 A;  2A1F A;  2J4L A;  3QUO A;  1GS5 A;  2BUF A;  2J0X A;  2R98 A;  2CDQ A;  2IJ9 A;  4KZT A;  2R8V A;  1OHB A;  3ZZI A;  4NDO A;  1GSJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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