3QUOA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with atp and fosfomycin
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
276
structure length
265
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDTILPEVDARSPEQAYAALWGSSAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITTTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
source organism Streptomyces wedmorensis
molecule tags Transferase/transferase inhibitor
molecule keywords FomA protein
total genus 80
structure length 265
sequence length 276
ec nomenclature
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3quoA00
4F6TA 3TVIA 2X2WA 2BNEA 2R98A 4F6TB 2BUFA 2OGXB 3QVHA 2J4JA 3D2PA 3C1MA 3AB2A 3U6UA 3ZZIA 2JJXA 3QUNA 3D40A 4NDRB 3QURA 2E9YA 2J4KA 2BTYA 4JZ7A 3NWYA 2J0XA 2RD5A 2WXBA 4NDQB 3LKKA 4NDOB 3EK5A 3T7BA 3C20A 2JI5A 3EK6A 4NDPA 4AB7A 1GSJA 4I49A 1YBDA 3K4YA 2WE5A 2OGXA 1GS5A 2V4YA 3L86A 2J4LA 3AB4A 2BMUA 3WWMA 2J0WA 3AAWA 3KZFA 2JJ4A 1Z9DA 4JZ8A 2W21A 4NDQA 2IJ9A 1OHAA 3D2MA 3C1NA 2HMFA 3ZZGA 3K4OA 3QVFA 3L76A 1OHBA 3S6KA 3LL5A 2VA1A 3S6GA 3ZZFA 4NDOA 4A7XA 3D41A 1E19A 3K56A 4NDRA 4A7WA 2V5HA 2CDQA 4Q1TA 2AP9A 4OLCA 4USJA 3LL9A 2BRXA 4JZ9A 2AKOA 4AXSA 2J5TA 1OH9A 3QUOA 3WWNA 2J5VA 3B8GA 2BNFA 2A1FA 3S6HA 1B7BA 4NDPB 2BNDA 3K52A 4KZTA 3ZZHA 2WE4A 2R8VA 2BRIA
chains in the Genus database with same CATH superfamily
4F6TA 3TVIA 2X2WA 2BNEA 2R98A 4F6TB 2BUFA 2OGXB 3QVHA 2J4JA 3D2PA 3C1MA 3AB2A 3U6UA 3ZZIA 2JJXA 3QUNA 3D40A 4NDRB 3QURA 2E9YA 2J4KA 2BTYA 4JZ7A 3NWYA 2J0XA 2RD5A 2WXBA 4NDQB 3LKKA 4NDOB 3EK5A 3T7BA 3C20A 2JI5A 3EK6A 4NDPA 4AB7A 1GSJA 4I49A 1YBDA 3K4YA 2WE5A 2OGXA 1GS5A 2V4YA 3L86A 2J4LA 3AB4A 2BMUA 3WWMA 2J0WA 3AAWA 3KZFA 2JJ4A 1Z9DA 4JZ8A 2W21A 4NDQA 2IJ9A 1OHAA 3D2MA 3C1NA 2HMFA 3ZZGA 3K4OA 3QVFA 3L76A 1OHBA 3S6KA 3LL5A 2VA1A 3S6GA 3ZZFA 4NDOA 4A7XA 3D41A 1E19A 3K56A 4NDRA 4A7WA 2V5HA 2CDQA 4Q1TA 2AP9A 4OLCA 4USJA 3LL9A 2BRXA 4JZ9A 2AKOA 4AXSA 2J5TA 1OH9A 3QUOA 3WWNA 2J5VA 3B8GA 2BNFA 2A1FA 3S6HA 1B7BA 4NDPB 2BNDA 3K52A 4KZTA 3ZZHA 2WE4A 2R8VA 2BRIA
chains in the Genus database with same CATH topology
4F6TA 3TVIA 2X2WA 2BNEA 2R98A 4F6TB 2BUFA 2OGXB 3QVHA 2J4JA 3D2PA 3C1MA 3AB2A 3U6UA 3ZZIA 2JJXA 3QUNA 3D40A 4NDRB 3QURA 2E9YA 2J4KA 2BTYA 4JZ7A 3NWYA 2J0XA 2RD5A 2WXBA 4NDQB 3LKKA 4NDOB 3EK5A 3T7BA 3C20A 2JI5A 3EK6A 4NDPA 4AB7A 1GSJA 4I49A 1YBDA 3K4YA 2WE5A 2OGXA 1GS5A 2V4YA 3L86A 2J4LA 3AB4A 2BMUA 3WWMA 2J0WA 3AAWA 3KZFA 2JJ4A 1Z9DA 4JZ8A 2W21A 4NDQA 2IJ9A 1OHAA 3D2MA 3C1NA 2HMFA 3ZZGA 3K4OA 3QVFA 3L76A 1OHBA 3S6KA 3LL5A 2VA1A 3S6GA 3ZZFA 4NDOA 4A7XA 3D41A 1E19A 3K56A 4NDRA 4A7WA 2V5HA 2CDQA 4Q1TA 2AP9A 4OLCA 4USJA 3LL9A 2BRXA 4JZ9A 2AKOA 4AXSA 2J5TA 1OH9A 3QUOA 3WWNA 2J5VA 3B8GA 2BNFA 2A1FA 3S6HA 1B7BA 4NDPB 2BNDA 3K52A 4KZTA 3ZZHA 2WE4A 2R8VA 2BRIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F6T A;  3TVI A;  2X2W A;  2BNE A;  2R98 A;  4F6T B;  2BUF A;  2OGX B;  3QVH A;  2J4J A;  3D2P A;  3C1M A;  3AB2 A;  3U6U A;  3ZZI A;  2JJX A;  3QUN A;  3D40 A;  4NDR B;  3QUR A;  2E9Y A;  2J4K A;  2BTY A;  4JZ7 A;  3NWY A;  2J0X A;  2RD5 A;  2WXB A;  4NDQ B;  3LKK A;  4NDO B;  3EK5 A;  3T7B A;  3C20 A;  2JI5 A;  3EK6 A;  4NDP A;  4AB7 A;  1GSJ A;  4I49 A;  1YBD A;  3K4Y A;  2WE5 A;  2OGX A;  1GS5 A;  2V4Y A;  3L86 A;  2J4L A;  3AB4 A;  2BMU A;  3WWM A;  2J0W A;  3AAW A;  3KZF A;  2JJ4 A;  1Z9D A;  4JZ8 A;  2W21 A;  4NDQ A;  2IJ9 A;  1OHA A;  3D2M A;  3C1N A;  2HMF A;  3ZZG A;  3K4O A;  3QVF A;  3L76 A;  1OHB A;  3S6K A;  3LL5 A;  2VA1 A;  3S6G A;  3ZZF A;  4NDO A;  4A7X A;  3D41 A;  1E19 A;  3K56 A;  4NDR A;  4A7W A;  2V5H A;  2CDQ A;  4Q1T A;  2AP9 A;  4OLC A;  4USJ A;  3LL9 A;  2BRX A;  4JZ9 A;  2AKO A;  4AXS A;  2J5T A;  1OH9 A;  3QUO A;  3WWN A;  2J5V A;  3B8G A;  2BNF A;  2A1F A;  3S6H A;  1B7B A;  4NDP B;  2BND A;  3K52 A;  4KZT A;  3ZZH A;  2WE4 A;  2R8V A;  2BRI A; 
#chains in the Genus database with same CATH topology
 4F6T A;  3TVI A;  2X2W A;  2BNE A;  2R98 A;  4F6T B;  2BUF A;  2OGX B;  3QVH A;  2J4J A;  3D2P A;  3C1M A;  3AB2 A;  3U6U A;  3ZZI A;  2JJX A;  3QUN A;  3D40 A;  4NDR B;  3QUR A;  2E9Y A;  2J4K A;  2BTY A;  4JZ7 A;  3NWY A;  2J0X A;  2RD5 A;  2WXB A;  4NDQ B;  3LKK A;  4NDO B;  3EK5 A;  3T7B A;  3C20 A;  2JI5 A;  3EK6 A;  4NDP A;  4AB7 A;  1GSJ A;  4I49 A;  1YBD A;  3K4Y A;  2WE5 A;  2OGX A;  1GS5 A;  2V4Y A;  3L86 A;  2J4L A;  3AB4 A;  2BMU A;  3WWM A;  2J0W A;  3AAW A;  3KZF A;  2JJ4 A;  1Z9D A;  4JZ8 A;  2W21 A;  4NDQ A;  2IJ9 A;  1OHA A;  3D2M A;  3C1N A;  2HMF A;  3ZZG A;  3K4O A;  3QVF A;  3L76 A;  1OHB A;  3S6K A;  3LL5 A;  2VA1 A;  3S6G A;  3ZZF A;  4NDO A;  4A7X A;  3D41 A;  1E19 A;  3K56 A;  4NDR A;  4A7W A;  2V5H A;  2CDQ A;  4Q1T A;  2AP9 A;  4OLC A;  4USJ A;  3LL9 A;  2BRX A;  4JZ9 A;  2AKO A;  4AXS A;  2J5T A;  1OH9 A;  3QUO A;  3WWN A;  2J5V A;  3B8G A;  2BNF A;  2A1F A;  3S6H A;  1B7B A;  4NDP B;  2BND A;  3K52 A;  4KZT A;  3ZZH A;  2WE4 A;  2R8V A;  2BRI A; 
#chains in the Genus database with same CATH homology
 4F6T A;  3TVI A;  2X2W A;  2BNE A;  2R98 A;  4F6T B;  2BUF A;  2OGX B;  3QVH A;  2J4J A;  3D2P A;  3C1M A;  3AB2 A;  3U6U A;  3ZZI A;  2JJX A;  3QUN A;  3D40 A;  4NDR B;  3QUR A;  2E9Y A;  2J4K A;  2BTY A;  4JZ7 A;  3NWY A;  2J0X A;  2RD5 A;  2WXB A;  4NDQ B;  3LKK A;  4NDO B;  3EK5 A;  3T7B A;  3C20 A;  2JI5 A;  3EK6 A;  4NDP A;  4AB7 A;  1GSJ A;  4I49 A;  1YBD A;  3K4Y A;  2WE5 A;  2OGX A;  1GS5 A;  2V4Y A;  3L86 A;  2J4L A;  3AB4 A;  2BMU A;  3WWM A;  2J0W A;  3AAW A;  3KZF A;  2JJ4 A;  1Z9D A;  4JZ8 A;  2W21 A;  4NDQ A;  2IJ9 A;  1OHA A;  3D2M A;  3C1N A;  2HMF A;  3ZZG A;  3K4O A;  3QVF A;  3L76 A;  1OHB A;  3S6K A;  3LL5 A;  2VA1 A;  3S6G A;  3ZZF A;  4NDO A;  4A7X A;  3D41 A;  1E19 A;  3K56 A;  4NDR A;  4A7W A;  2V5H A;  2CDQ A;  4Q1T A;  2AP9 A;  4OLC A;  4USJ A;  3LL9 A;  2BRX A;  4JZ9 A;  2AKO A;  4AXS A;  2J5T A;  1OH9 A;  3QUO A;  3WWN A;  2J5V A;  3B8G A;  2BNF A;  2A1F A;  3S6H A;  1B7B A;  4NDP B;  2BND A;  3K52 A;  4KZT A;  3ZZH A;  2WE4 A;  2R8V A;  2BRI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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