3QUOA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with atp and fosfomycin
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
276
structure length
265
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDTILPEVDARSPEQAYAALWGSSAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITTTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords FomA protein
publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
source organism Streptomyces wedmorensis
total genus 80
structure length 265
sequence length 276
ec nomenclature
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3quoA00
3QUOA 4JZ8A 3S6HA 3D2PA 3QVHA 2A1FA 2J0XA 1E19A 2BUFA 2E9YA 4USJA 3TVIA 3C1NA 3LKKA 4JZ9A 3C1MA 3B8GA 3AB4A 4NDRA 2R8VA 1B7BA 2BNDA 1OHBA 4A7XA 3C20A 2BRXA 2J0WA 3LL5A 3L86A 2AKOA 2R98A 4NDQA 1GS5A 2BMUA 2BNEA 3S6GA 4KZTA 2W21A 2RD5A 2J5TA 4F6TB 3ZZFA 3K4YA 2JJXA 4JZ7A 4NDRB 3S6KA 3EK5A 2OGXA 1GSJA 2J4KA 3K52A 3WWMA 3WWNA 3D40A 1OHAA 3ZZIA 2BNFA 2BRIA 2WE5A 2AP9A 3D2MA 4NDQB 3KZFA 2JI5A 4NDPB 3LL9A 3EK6A 4OLCA 3K4OA 3AB2A 2CDQA 3T7BA 2J5VA 4NDOA 3ZZHA 3D41A 2V4YA 2OGXB 2BTYA 4AXSA 2J4LA 3QVFA 2WE4A 4I49A 2V5HA 2HMFA 2WXBA 3ZZGA 3U6UA 3QUNA 4F6TA 1Z9DA 2JJ4A 4A7WA 2X2WA 1OH9A 4NDOB 4AB7A 2VA1A 2J4JA 2IJ9A 3K56A 3AAWA 4Q1TA 3NWYA 3QURA 3L76A 4NDPA 1YBDA
chains in the Genus database with same CATH superfamily
3QUOA 4JZ8A 3S6HA 3D2PA 3QVHA 2A1FA 2J0XA 1E19A 2BUFA 2E9YA 4USJA 3TVIA 3C1NA 3LKKA 4JZ9A 3C1MA 3B8GA 3AB4A 4NDRA 2R8VA 1B7BA 2BNDA 1OHBA 4A7XA 3C20A 2BRXA 2J0WA 3LL5A 3L86A 2AKOA 2R98A 4NDQA 1GS5A 2BMUA 2BNEA 3S6GA 4KZTA 2W21A 2RD5A 2J5TA 4F6TB 3ZZFA 3K4YA 2JJXA 4JZ7A 4NDRB 3S6KA 3EK5A 2OGXA 1GSJA 2J4KA 3K52A 3WWMA 3WWNA 3D40A 1OHAA 3ZZIA 2BNFA 2BRIA 2WE5A 2AP9A 3D2MA 4NDQB 3KZFA 2JI5A 4NDPB 3LL9A 3EK6A 4OLCA 3K4OA 3AB2A 2CDQA 3T7BA 2J5VA 4NDOA 3ZZHA 3D41A 2V4YA 2OGXB 2BTYA 4AXSA 2J4LA 3QVFA 2WE4A 4I49A 2V5HA 2HMFA 2WXBA 3ZZGA 3U6UA 3QUNA 4F6TA 1Z9DA 2JJ4A 4A7WA 2X2WA 1OH9A 4NDOB 4AB7A 2VA1A 2J4JA 2IJ9A 3K56A 3AAWA 4Q1TA 3NWYA 3QURA 3L76A 4NDPA 1YBDA
chains in the Genus database with same CATH topology
3QUOA 4JZ8A 3S6HA 3D2PA 3QVHA 2A1FA 2J0XA 1E19A 2BUFA 2E9YA 4USJA 3TVIA 3C1NA 3LKKA 4JZ9A 3C1MA 3B8GA 3AB4A 4NDRA 2R8VA 1B7BA 2BNDA 1OHBA 4A7XA 3C20A 2BRXA 2J0WA 3LL5A 3L86A 2AKOA 2R98A 4NDQA 1GS5A 2BMUA 2BNEA 3S6GA 4KZTA 2W21A 2RD5A 2J5TA 4F6TB 3ZZFA 3K4YA 2JJXA 4JZ7A 4NDRB 3S6KA 3EK5A 2OGXA 1GSJA 2J4KA 3K52A 3WWMA 3WWNA 3D40A 1OHAA 3ZZIA 2BNFA 2BRIA 2WE5A 2AP9A 3D2MA 4NDQB 3KZFA 2JI5A 4NDPB 3LL9A 3EK6A 4OLCA 3K4OA 3AB2A 2CDQA 3T7BA 2J5VA 4NDOA 3ZZHA 3D41A 2V4YA 2OGXB 2BTYA 4AXSA 2J4LA 3QVFA 2WE4A 4I49A 2V5HA 2HMFA 2WXBA 3ZZGA 3U6UA 3QUNA 4F6TA 1Z9DA 2JJ4A 4A7WA 2X2WA 1OH9A 4NDOB 4AB7A 2VA1A 2J4JA 2IJ9A 3K56A 3AAWA 4Q1TA 3NWYA 3QURA 3L76A 4NDPA 1YBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QUO A;  4JZ8 A;  3S6H A;  3D2P A;  3QVH A;  2A1F A;  2J0X A;  1E19 A;  2BUF A;  2E9Y A;  4USJ A;  3TVI A;  3C1N A;  3LKK A;  4JZ9 A;  3C1M A;  3B8G A;  3AB4 A;  4NDR A;  2R8V A;  1B7B A;  2BND A;  1OHB A;  4A7X A;  3C20 A;  2BRX A;  2J0W A;  3LL5 A;  3L86 A;  2AKO A;  2R98 A;  4NDQ A;  1GS5 A;  2BMU A;  2BNE A;  3S6G A;  4KZT A;  2W21 A;  2RD5 A;  2J5T A;  4F6T B;  3ZZF A;  3K4Y A;  2JJX A;  4JZ7 A;  4NDR B;  3S6K A;  3EK5 A;  2OGX A;  1GSJ A;  2J4K A;  3K52 A;  3WWM A;  3WWN A;  3D40 A;  1OHA A;  3ZZI A;  2BNF A;  2BRI A;  2WE5 A;  2AP9 A;  3D2M A;  4NDQ B;  3KZF A;  2JI5 A;  4NDP B;  3LL9 A;  3EK6 A;  4OLC A;  3K4O A;  3AB2 A;  2CDQ A;  3T7B A;  2J5V A;  4NDO A;  3ZZH A;  3D41 A;  2V4Y A;  2OGX B;  2BTY A;  4AXS A;  2J4L A;  3QVF A;  2WE4 A;  4I49 A;  2V5H A;  2HMF A;  2WXB A;  3ZZG A;  3U6U A;  3QUN A;  4F6T A;  1Z9D A;  2JJ4 A;  4A7W A;  2X2W A;  1OH9 A;  4NDO B;  4AB7 A;  2VA1 A;  2J4J A;  2IJ9 A;  3K56 A;  3AAW A;  4Q1T A;  3NWY A;  3QUR A;  3L76 A;  4NDP A;  1YBD A; 
#chains in the Genus database with same CATH topology
 3QUO A;  4JZ8 A;  3S6H A;  3D2P A;  3QVH A;  2A1F A;  2J0X A;  1E19 A;  2BUF A;  2E9Y A;  4USJ A;  3TVI A;  3C1N A;  3LKK A;  4JZ9 A;  3C1M A;  3B8G A;  3AB4 A;  4NDR A;  2R8V A;  1B7B A;  2BND A;  1OHB A;  4A7X A;  3C20 A;  2BRX A;  2J0W A;  3LL5 A;  3L86 A;  2AKO A;  2R98 A;  4NDQ A;  1GS5 A;  2BMU A;  2BNE A;  3S6G A;  4KZT A;  2W21 A;  2RD5 A;  2J5T A;  4F6T B;  3ZZF A;  3K4Y A;  2JJX A;  4JZ7 A;  4NDR B;  3S6K A;  3EK5 A;  2OGX A;  1GSJ A;  2J4K A;  3K52 A;  3WWM A;  3WWN A;  3D40 A;  1OHA A;  3ZZI A;  2BNF A;  2BRI A;  2WE5 A;  2AP9 A;  3D2M A;  4NDQ B;  3KZF A;  2JI5 A;  4NDP B;  3LL9 A;  3EK6 A;  4OLC A;  3K4O A;  3AB2 A;  2CDQ A;  3T7B A;  2J5V A;  4NDO A;  3ZZH A;  3D41 A;  2V4Y A;  2OGX B;  2BTY A;  4AXS A;  2J4L A;  3QVF A;  2WE4 A;  4I49 A;  2V5H A;  2HMF A;  2WXB A;  3ZZG A;  3U6U A;  3QUN A;  4F6T A;  1Z9D A;  2JJ4 A;  4A7W A;  2X2W A;  1OH9 A;  4NDO B;  4AB7 A;  2VA1 A;  2J4J A;  2IJ9 A;  3K56 A;  3AAW A;  4Q1T A;  3NWY A;  3QUR A;  3L76 A;  4NDP A;  1YBD A; 
#chains in the Genus database with same CATH homology
 3QUO A;  4JZ8 A;  3S6H A;  3D2P A;  3QVH A;  2A1F A;  2J0X A;  1E19 A;  2BUF A;  2E9Y A;  4USJ A;  3TVI A;  3C1N A;  3LKK A;  4JZ9 A;  3C1M A;  3B8G A;  3AB4 A;  4NDR A;  2R8V A;  1B7B A;  2BND A;  1OHB A;  4A7X A;  3C20 A;  2BRX A;  2J0W A;  3LL5 A;  3L86 A;  2AKO A;  2R98 A;  4NDQ A;  1GS5 A;  2BMU A;  2BNE A;  3S6G A;  4KZT A;  2W21 A;  2RD5 A;  2J5T A;  4F6T B;  3ZZF A;  3K4Y A;  2JJX A;  4JZ7 A;  4NDR B;  3S6K A;  3EK5 A;  2OGX A;  1GSJ A;  2J4K A;  3K52 A;  3WWM A;  3WWN A;  3D40 A;  1OHA A;  3ZZI A;  2BNF A;  2BRI A;  2WE5 A;  2AP9 A;  3D2M A;  4NDQ B;  3KZF A;  2JI5 A;  4NDP B;  3LL9 A;  3EK6 A;  4OLC A;  3K4O A;  3AB2 A;  2CDQ A;  3T7B A;  2J5V A;  4NDO A;  3ZZH A;  3D41 A;  2V4Y A;  2OGX B;  2BTY A;  4AXS A;  2J4L A;  3QVF A;  2WE4 A;  4I49 A;  2V5H A;  2HMF A;  2WXB A;  3ZZG A;  3U6U A;  3QUN A;  4F6T A;  1Z9D A;  2JJ4 A;  4A7W A;  2X2W A;  1OH9 A;  4NDO B;  4AB7 A;  2VA1 A;  2J4J A;  2IJ9 A;  3K56 A;  3AAW A;  4Q1T A;  3NWY A;  3QUR A;  3L76 A;  4NDP A;  1YBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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