3QUOA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with atp and fosfomycin
Total Genus 80
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
276
structure length
265
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDTILPEVDARSPEQAYAALWGSSAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITTTA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
source organism Streptomyces wedmorensis
molecule tags Transferase/transferase inhibitor
molecule keywords FomA protein
total genus 80
structure length 265
sequence length 276
ec nomenclature
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3quoA00
3LKKA 3K4YA 1GSJA 3S6KA 2BRIA 3C20A 3ZZFA 2J4LA 2BNDA 4NDPA 4A7XA 3TVIA 2WE4A 1B7BA 3K52A 2BTYA 3D2MA 4OLCA 4I49A 3L76A 2BUFA 3T7BA 4AB7A 2E9YA 3K4OA 2VA1A 1OHAA 4NDQB 3S6GA 3QURA 3AAWA 2V4YA 4JZ7A 3WWMA 2OGXA 2BRXA 4NDOB 4NDQA 4NDOA 3ZZHA 4Q1TA 1E19A 4KZTA 4JZ8A 3B8GA 1GS5A 2OGXB 2AKOA 3D40A 4A7WA 2X2WA 2J4JA 3ZZIA 4NDPB 2BMUA 4USJA 3C1NA 2AP9A 4NDRB 3WWNA 3AB4A 3D2PA 3KZFA 3NWYA 3EK6A 2WXBA 3ZZGA 2J5TA 3D41A 2A1FA 3U6UA 2RD5A 3C1MA 2J0WA 2CDQA 3QVFA 1YBDA 2R98A 2BNFA 2J0XA 2BNEA 4F6TB 2R8VA 1OHBA 1Z9DA 3EK5A 4JZ9A 3L86A 3LL5A 3S6HA 2JJ4A 3AB2A 2JJXA 2HMFA 2J5VA 2WE5A 2W21A 3QUNA 3LL9A 2JI5A 4AXSA 2V5HA 2J4KA 3QVHA 3QUOA 1OH9A 3K56A 4NDRA 2IJ9A 4F6TA
chains in the Genus database with same CATH superfamily
3LKKA 3K4YA 1GSJA 3S6KA 2BRIA 3C20A 3ZZFA 2J4LA 2BNDA 4NDPA 4A7XA 3TVIA 2WE4A 1B7BA 3K52A 2BTYA 3D2MA 4OLCA 4I49A 3L76A 2BUFA 3T7BA 4AB7A 2E9YA 3K4OA 2VA1A 1OHAA 4NDQB 3S6GA 3QURA 3AAWA 2V4YA 4JZ7A 3WWMA 2OGXA 2BRXA 4NDOB 4NDQA 4NDOA 3ZZHA 4Q1TA 1E19A 4KZTA 4JZ8A 3B8GA 1GS5A 2OGXB 2AKOA 3D40A 4A7WA 2X2WA 2J4JA 3ZZIA 4NDPB 2BMUA 4USJA 3C1NA 2AP9A 4NDRB 3WWNA 3AB4A 3D2PA 3KZFA 3NWYA 3EK6A 2WXBA 3ZZGA 2J5TA 3D41A 2A1FA 3U6UA 2RD5A 3C1MA 2J0WA 2CDQA 3QVFA 1YBDA 2R98A 2BNFA 2J0XA 2BNEA 4F6TB 2R8VA 1OHBA 1Z9DA 3EK5A 4JZ9A 3L86A 3LL5A 3S6HA 2JJ4A 3AB2A 2JJXA 2HMFA 2J5VA 2WE5A 2W21A 3QUNA 3LL9A 2JI5A 4AXSA 2V5HA 2J4KA 3QVHA 3QUOA 1OH9A 3K56A 4NDRA 2IJ9A 4F6TA
chains in the Genus database with same CATH topology
3LKKA 3K4YA 1GSJA 3S6KA 2BRIA 3C20A 3ZZFA 2J4LA 2BNDA 4NDPA 4A7XA 3TVIA 2WE4A 1B7BA 3K52A 2BTYA 3D2MA 4OLCA 4I49A 3L76A 2BUFA 3T7BA 4AB7A 2E9YA 3K4OA 2VA1A 1OHAA 4NDQB 3S6GA 3QURA 3AAWA 2V4YA 4JZ7A 3WWMA 2OGXA 2BRXA 4NDOB 4NDQA 4NDOA 3ZZHA 4Q1TA 1E19A 4KZTA 4JZ8A 3B8GA 1GS5A 2OGXB 2AKOA 3D40A 4A7WA 2X2WA 2J4JA 3ZZIA 4NDPB 2BMUA 4USJA 3C1NA 2AP9A 4NDRB 3WWNA 3AB4A 3D2PA 3KZFA 3NWYA 3EK6A 2WXBA 3ZZGA 2J5TA 3D41A 2A1FA 3U6UA 2RD5A 3C1MA 2J0WA 2CDQA 3QVFA 1YBDA 2R98A 2BNFA 2J0XA 2BNEA 4F6TB 2R8VA 1OHBA 1Z9DA 3EK5A 4JZ9A 3L86A 3LL5A 3S6HA 2JJ4A 3AB2A 2JJXA 2HMFA 2J5VA 2WE5A 2W21A 3QUNA 3LL9A 2JI5A 4AXSA 2V5HA 2J4KA 3QVHA 3QUOA 1OH9A 3K56A 4NDRA 2IJ9A 4F6TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LKK A;  3K4Y A;  1GSJ A;  3S6K A;  2BRI A;  3C20 A;  3ZZF A;  2J4L A;  2BND A;  4NDP A;  4A7X A;  3TVI A;  2WE4 A;  1B7B A;  3K52 A;  2BTY A;  3D2M A;  4OLC A;  4I49 A;  3L76 A;  2BUF A;  3T7B A;  4AB7 A;  2E9Y A;  3K4O A;  2VA1 A;  1OHA A;  4NDQ B;  3S6G A;  3QUR A;  3AAW A;  2V4Y A;  4JZ7 A;  3WWM A;  2OGX A;  2BRX A;  4NDO B;  4NDQ A;  4NDO A;  3ZZH A;  4Q1T A;  1E19 A;  4KZT A;  4JZ8 A;  3B8G A;  1GS5 A;  2OGX B;  2AKO A;  3D40 A;  4A7W A;  2X2W A;  2J4J A;  3ZZI A;  4NDP B;  2BMU A;  4USJ A;  3C1N A;  2AP9 A;  4NDR B;  3WWN A;  3AB4 A;  3D2P A;  3KZF A;  3NWY A;  3EK6 A;  2WXB A;  3ZZG A;  2J5T A;  3D41 A;  2A1F A;  3U6U A;  2RD5 A;  3C1M A;  2J0W A;  2CDQ A;  3QVF A;  1YBD A;  2R98 A;  2BNF A;  2J0X A;  2BNE A;  4F6T B;  2R8V A;  1OHB A;  1Z9D A;  3EK5 A;  4JZ9 A;  3L86 A;  3LL5 A;  3S6H A;  2JJ4 A;  3AB2 A;  2JJX A;  2HMF A;  2J5V A;  2WE5 A;  2W21 A;  3QUN A;  3LL9 A;  2JI5 A;  4AXS A;  2V5H A;  2J4K A;  3QVH A;  3QUO A;  1OH9 A;  3K56 A;  4NDR A;  2IJ9 A;  4F6T A; 
#chains in the Genus database with same CATH topology
 3LKK A;  3K4Y A;  1GSJ A;  3S6K A;  2BRI A;  3C20 A;  3ZZF A;  2J4L A;  2BND A;  4NDP A;  4A7X A;  3TVI A;  2WE4 A;  1B7B A;  3K52 A;  2BTY A;  3D2M A;  4OLC A;  4I49 A;  3L76 A;  2BUF A;  3T7B A;  4AB7 A;  2E9Y A;  3K4O A;  2VA1 A;  1OHA A;  4NDQ B;  3S6G A;  3QUR A;  3AAW A;  2V4Y A;  4JZ7 A;  3WWM A;  2OGX A;  2BRX A;  4NDO B;  4NDQ A;  4NDO A;  3ZZH A;  4Q1T A;  1E19 A;  4KZT A;  4JZ8 A;  3B8G A;  1GS5 A;  2OGX B;  2AKO A;  3D40 A;  4A7W A;  2X2W A;  2J4J A;  3ZZI A;  4NDP B;  2BMU A;  4USJ A;  3C1N A;  2AP9 A;  4NDR B;  3WWN A;  3AB4 A;  3D2P A;  3KZF A;  3NWY A;  3EK6 A;  2WXB A;  3ZZG A;  2J5T A;  3D41 A;  2A1F A;  3U6U A;  2RD5 A;  3C1M A;  2J0W A;  2CDQ A;  3QVF A;  1YBD A;  2R98 A;  2BNF A;  2J0X A;  2BNE A;  4F6T B;  2R8V A;  1OHB A;  1Z9D A;  3EK5 A;  4JZ9 A;  3L86 A;  3LL5 A;  3S6H A;  2JJ4 A;  3AB2 A;  2JJX A;  2HMF A;  2J5V A;  2WE5 A;  2W21 A;  3QUN A;  3LL9 A;  2JI5 A;  4AXS A;  2V5H A;  2J4K A;  3QVH A;  3QUO A;  1OH9 A;  3K56 A;  4NDR A;  2IJ9 A;  4F6T A; 
#chains in the Genus database with same CATH homology
 3LKK A;  3K4Y A;  1GSJ A;  3S6K A;  2BRI A;  3C20 A;  3ZZF A;  2J4L A;  2BND A;  4NDP A;  4A7X A;  3TVI A;  2WE4 A;  1B7B A;  3K52 A;  2BTY A;  3D2M A;  4OLC A;  4I49 A;  3L76 A;  2BUF A;  3T7B A;  4AB7 A;  2E9Y A;  3K4O A;  2VA1 A;  1OHA A;  4NDQ B;  3S6G A;  3QUR A;  3AAW A;  2V4Y A;  4JZ7 A;  3WWM A;  2OGX A;  2BRX A;  4NDO B;  4NDQ A;  4NDO A;  3ZZH A;  4Q1T A;  1E19 A;  4KZT A;  4JZ8 A;  3B8G A;  1GS5 A;  2OGX B;  2AKO A;  3D40 A;  4A7W A;  2X2W A;  2J4J A;  3ZZI A;  4NDP B;  2BMU A;  4USJ A;  3C1N A;  2AP9 A;  4NDR B;  3WWN A;  3AB4 A;  3D2P A;  3KZF A;  3NWY A;  3EK6 A;  2WXB A;  3ZZG A;  2J5T A;  3D41 A;  2A1F A;  3U6U A;  2RD5 A;  3C1M A;  2J0W A;  2CDQ A;  3QVF A;  1YBD A;  2R98 A;  2BNF A;  2J0X A;  2BNE A;  4F6T B;  2R8V A;  1OHB A;  1Z9D A;  3EK5 A;  4JZ9 A;  3L86 A;  3LL5 A;  3S6H A;  2JJ4 A;  3AB2 A;  2JJX A;  2HMF A;  2J5V A;  2WE5 A;  2W21 A;  3QUN A;  3LL9 A;  2JI5 A;  4AXS A;  2V5H A;  2J4K A;  3QVH A;  3QUO A;  1OH9 A;  3K56 A;  4NDR A;  2IJ9 A;  4F6T A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...