3QUOA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with atp and fosfomycin
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
276
structure length
265
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDTILPEVDARSPEQAYAALWGSSAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITTTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FomA protein
publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
source organism Streptomyces wedmorensis
molecule tags Transferase/transferase inhibitor
total genus 80
structure length 265
sequence length 276
ec nomenclature
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3quoA00
2A1FA 3QVFA 4KZTA 2R8VA 3B8GA 3C20A 2BMUA 3S6HA 3C1NA 3QURA 1OHBA 1Z9DA 2R98A 2BNEA 1E19A 4NDPA 4AXSA 1YBDA 2OGXB 2BTYA 4NDQB 3S6KA 4F6TB 3K52A 4NDOA 2RD5A 3AB2A 1OHAA 2JJXA 3LL9A 2V4YA 3K4YA 3QUOA 3ZZFA 2AP9A 3K4OA 2BUFA 2W21A 3WWMA 2E9YA 4AB7A 3D2PA 3K56A 2J0XA 2J5TA 4NDRB 3TVIA 3WWNA 3LKKA 2OGXA 1GS5A 4USJA 2J4LA 1GSJA 3L86A 3U6UA 2BNFA 3ZZHA 3C1MA 4JZ8A 2J4KA 3AAWA 3D41A 2J5VA 2VA1A 3D40A 3EK5A 4JZ7A 2BRIA 4JZ9A 4Q1TA 2HMFA 4OLCA 3QVHA 3ZZIA 4NDQA 4F6TA 4A7WA 2IJ9A 3KZFA 2JJ4A 3LL5A 2J0WA 2CDQA 3T7BA 3NWYA 2AKOA 2BRXA 3S6GA 3D2MA 3L76A 4I49A 1OH9A 4A7XA 2BNDA 2J4JA 2V5HA 4NDRA 2JI5A 2WE4A 1B7BA 3ZZGA 3QUNA 3EK6A 4NDPB 2X2WA 3AB4A 2WXBA 4NDOB 2WE5A
chains in the Genus database with same CATH superfamily
2A1FA 3QVFA 4KZTA 2R8VA 3B8GA 3C20A 2BMUA 3S6HA 3C1NA 3QURA 1OHBA 1Z9DA 2R98A 2BNEA 1E19A 4NDPA 4AXSA 1YBDA 2OGXB 2BTYA 4NDQB 3S6KA 4F6TB 3K52A 4NDOA 2RD5A 3AB2A 1OHAA 2JJXA 3LL9A 2V4YA 3K4YA 3QUOA 3ZZFA 2AP9A 3K4OA 2BUFA 2W21A 3WWMA 2E9YA 4AB7A 3D2PA 3K56A 2J0XA 2J5TA 4NDRB 3TVIA 3WWNA 3LKKA 2OGXA 1GS5A 4USJA 2J4LA 1GSJA 3L86A 3U6UA 2BNFA 3ZZHA 3C1MA 4JZ8A 2J4KA 3AAWA 3D41A 2J5VA 2VA1A 3D40A 3EK5A 4JZ7A 2BRIA 4JZ9A 4Q1TA 2HMFA 4OLCA 3QVHA 3ZZIA 4NDQA 4F6TA 4A7WA 2IJ9A 3KZFA 2JJ4A 3LL5A 2J0WA 2CDQA 3T7BA 3NWYA 2AKOA 2BRXA 3S6GA 3D2MA 3L76A 4I49A 1OH9A 4A7XA 2BNDA 2J4JA 2V5HA 4NDRA 2JI5A 2WE4A 1B7BA 3ZZGA 3QUNA 3EK6A 4NDPB 2X2WA 3AB4A 2WXBA 4NDOB 2WE5A
chains in the Genus database with same CATH topology
2A1FA 3QVFA 4KZTA 2R8VA 3B8GA 3C20A 2BMUA 3S6HA 3C1NA 3QURA 1OHBA 1Z9DA 2R98A 2BNEA 1E19A 4NDPA 4AXSA 1YBDA 2OGXB 2BTYA 4NDQB 3S6KA 4F6TB 3K52A 4NDOA 2RD5A 3AB2A 1OHAA 2JJXA 3LL9A 2V4YA 3K4YA 3QUOA 3ZZFA 2AP9A 3K4OA 2BUFA 2W21A 3WWMA 2E9YA 4AB7A 3D2PA 3K56A 2J0XA 2J5TA 4NDRB 3TVIA 3WWNA 3LKKA 2OGXA 1GS5A 4USJA 2J4LA 1GSJA 3L86A 3U6UA 2BNFA 3ZZHA 3C1MA 4JZ8A 2J4KA 3AAWA 3D41A 2J5VA 2VA1A 3D40A 3EK5A 4JZ7A 2BRIA 4JZ9A 4Q1TA 2HMFA 4OLCA 3QVHA 3ZZIA 4NDQA 4F6TA 4A7WA 2IJ9A 3KZFA 2JJ4A 3LL5A 2J0WA 2CDQA 3T7BA 3NWYA 2AKOA 2BRXA 3S6GA 3D2MA 3L76A 4I49A 1OH9A 4A7XA 2BNDA 2J4JA 2V5HA 4NDRA 2JI5A 2WE4A 1B7BA 3ZZGA 3QUNA 3EK6A 4NDPB 2X2WA 3AB4A 2WXBA 4NDOB 2WE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A1F A;  3QVF A;  4KZT A;  2R8V A;  3B8G A;  3C20 A;  2BMU A;  3S6H A;  3C1N A;  3QUR A;  1OHB A;  1Z9D A;  2R98 A;  2BNE A;  1E19 A;  4NDP A;  4AXS A;  1YBD A;  2OGX B;  2BTY A;  4NDQ B;  3S6K A;  4F6T B;  3K52 A;  4NDO A;  2RD5 A;  3AB2 A;  1OHA A;  2JJX A;  3LL9 A;  2V4Y A;  3K4Y A;  3QUO A;  3ZZF A;  2AP9 A;  3K4O A;  2BUF A;  2W21 A;  3WWM A;  2E9Y A;  4AB7 A;  3D2P A;  3K56 A;  2J0X A;  2J5T A;  4NDR B;  3TVI A;  3WWN A;  3LKK A;  2OGX A;  1GS5 A;  4USJ A;  2J4L A;  1GSJ A;  3L86 A;  3U6U A;  2BNF A;  3ZZH A;  3C1M A;  4JZ8 A;  2J4K A;  3AAW A;  3D41 A;  2J5V A;  2VA1 A;  3D40 A;  3EK5 A;  4JZ7 A;  2BRI A;  4JZ9 A;  4Q1T A;  2HMF A;  4OLC A;  3QVH A;  3ZZI A;  4NDQ A;  4F6T A;  4A7W A;  2IJ9 A;  3KZF A;  2JJ4 A;  3LL5 A;  2J0W A;  2CDQ A;  3T7B A;  3NWY A;  2AKO A;  2BRX A;  3S6G A;  3D2M A;  3L76 A;  4I49 A;  1OH9 A;  4A7X A;  2BND A;  2J4J A;  2V5H A;  4NDR A;  2JI5 A;  2WE4 A;  1B7B A;  3ZZG A;  3QUN A;  3EK6 A;  4NDP B;  2X2W A;  3AB4 A;  2WXB A;  4NDO B;  2WE5 A; 
#chains in the Genus database with same CATH topology
 2A1F A;  3QVF A;  4KZT A;  2R8V A;  3B8G A;  3C20 A;  2BMU A;  3S6H A;  3C1N A;  3QUR A;  1OHB A;  1Z9D A;  2R98 A;  2BNE A;  1E19 A;  4NDP A;  4AXS A;  1YBD A;  2OGX B;  2BTY A;  4NDQ B;  3S6K A;  4F6T B;  3K52 A;  4NDO A;  2RD5 A;  3AB2 A;  1OHA A;  2JJX A;  3LL9 A;  2V4Y A;  3K4Y A;  3QUO A;  3ZZF A;  2AP9 A;  3K4O A;  2BUF A;  2W21 A;  3WWM A;  2E9Y A;  4AB7 A;  3D2P A;  3K56 A;  2J0X A;  2J5T A;  4NDR B;  3TVI A;  3WWN A;  3LKK A;  2OGX A;  1GS5 A;  4USJ A;  2J4L A;  1GSJ A;  3L86 A;  3U6U A;  2BNF A;  3ZZH A;  3C1M A;  4JZ8 A;  2J4K A;  3AAW A;  3D41 A;  2J5V A;  2VA1 A;  3D40 A;  3EK5 A;  4JZ7 A;  2BRI A;  4JZ9 A;  4Q1T A;  2HMF A;  4OLC A;  3QVH A;  3ZZI A;  4NDQ A;  4F6T A;  4A7W A;  2IJ9 A;  3KZF A;  2JJ4 A;  3LL5 A;  2J0W A;  2CDQ A;  3T7B A;  3NWY A;  2AKO A;  2BRX A;  3S6G A;  3D2M A;  3L76 A;  4I49 A;  1OH9 A;  4A7X A;  2BND A;  2J4J A;  2V5H A;  4NDR A;  2JI5 A;  2WE4 A;  1B7B A;  3ZZG A;  3QUN A;  3EK6 A;  4NDP B;  2X2W A;  3AB4 A;  2WXB A;  4NDO B;  2WE5 A; 
#chains in the Genus database with same CATH homology
 2A1F A;  3QVF A;  4KZT A;  2R8V A;  3B8G A;  3C20 A;  2BMU A;  3S6H A;  3C1N A;  3QUR A;  1OHB A;  1Z9D A;  2R98 A;  2BNE A;  1E19 A;  4NDP A;  4AXS A;  1YBD A;  2OGX B;  2BTY A;  4NDQ B;  3S6K A;  4F6T B;  3K52 A;  4NDO A;  2RD5 A;  3AB2 A;  1OHA A;  2JJX A;  3LL9 A;  2V4Y A;  3K4Y A;  3QUO A;  3ZZF A;  2AP9 A;  3K4O A;  2BUF A;  2W21 A;  3WWM A;  2E9Y A;  4AB7 A;  3D2P A;  3K56 A;  2J0X A;  2J5T A;  4NDR B;  3TVI A;  3WWN A;  3LKK A;  2OGX A;  1GS5 A;  4USJ A;  2J4L A;  1GSJ A;  3L86 A;  3U6U A;  2BNF A;  3ZZH A;  3C1M A;  4JZ8 A;  2J4K A;  3AAW A;  3D41 A;  2J5V A;  2VA1 A;  3D40 A;  3EK5 A;  4JZ7 A;  2BRI A;  4JZ9 A;  4Q1T A;  2HMF A;  4OLC A;  3QVH A;  3ZZI A;  4NDQ A;  4F6T A;  4A7W A;  2IJ9 A;  3KZF A;  2JJ4 A;  3LL5 A;  2J0W A;  2CDQ A;  3T7B A;  3NWY A;  2AKO A;  2BRX A;  3S6G A;  3D2M A;  3L76 A;  4I49 A;  1OH9 A;  4A7X A;  2BND A;  2J4J A;  2V5H A;  4NDR A;  2JI5 A;  2WE4 A;  1B7B A;  3ZZG A;  3QUN A;  3EK6 A;  4NDP B;  2X2W A;  3AB4 A;  2WXB A;  4NDO B;  2WE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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