2J4KA

Crystal structure of uridylate kinase from sulfolobus solfataricus in complex with ump to 2.2 angstrom resolution
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
226
structure length
207
Chain Sequence
MNIILKISGKFFDEDNVDNLIVLRQSIKELADNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRIYADVKLIPHLTTQDLRKILLLDPLAIKIVERSKIRVIVMNYRKLNRIEVSSIIEPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus solfataricus
molecule keywords URIDYLATE KINASE
total genus 68
structure length 207
sequence length 226
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2006-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j4kA00
3T7BA 3ZZIA 2JJXA 2R8VA 3ZZFA 3D41A 4AXSA 4OLCA 2AP9A 3LKKA 4A7WA 3QURA 2BNFA 1OH9A 2JJ4A 3D40A 3NWYA 3C20A 2BTYA 4NDQB 3QUNA 4F6TB 3EK5A 3L76A 4NDRB 3AB4A 3ZZHA 3S6HA 4AB7A 1Z9DA 3B8GA 2R98A 4KZTA 3ZZGA 2BRIA 2BNEA 1B7BA 2BMUA 3L86A 2J5VA 1GSJA 4Q1TA 1YBDA 3LL5A 3K56A 3WWNA 4JZ7A 3K4YA 3S6KA 3K52A 3EK6A 2W21A 2BNDA 3D2PA 4NDPB 2RD5A 1OHAA 2J5TA 3QUOA 3AB2A 3WWMA 2OGXB 4NDQA 3TVIA 4NDOB 2WE4A 4F6TA 2V5HA 2WE5A 4NDRA 2J4JA 1GS5A 2VA1A 2X2WA 2A1FA 2BRXA 2J4KA 3S6GA 3C1NA 2WXBA 3C1MA 4JZ9A 2J0WA 2CDQA 3AAWA 4USJA 3LL9A 4A7XA 4I49A 2J4LA 3QVFA 1E19A 2JI5A 3U6UA 2E9YA 2AKOA 2V4YA 4NDPA 3D2MA 2HMFA 2J0XA 3K4OA 1OHBA 3QVHA 4JZ8A 2OGXA 4NDOA 3KZFA 2BUFA 2IJ9A
chains in the Genus database with same CATH superfamily
3T7BA 3ZZIA 2JJXA 2R8VA 3ZZFA 3D41A 4AXSA 4OLCA 2AP9A 3LKKA 4A7WA 3QURA 2BNFA 1OH9A 2JJ4A 3D40A 3NWYA 3C20A 2BTYA 4NDQB 3QUNA 4F6TB 3EK5A 3L76A 4NDRB 3AB4A 3ZZHA 3S6HA 4AB7A 1Z9DA 3B8GA 2R98A 4KZTA 3ZZGA 2BRIA 2BNEA 1B7BA 2BMUA 3L86A 2J5VA 1GSJA 4Q1TA 1YBDA 3LL5A 3K56A 3WWNA 4JZ7A 3K4YA 3S6KA 3K52A 3EK6A 2W21A 2BNDA 3D2PA 4NDPB 2RD5A 1OHAA 2J5TA 3QUOA 3AB2A 3WWMA 2OGXB 4NDQA 3TVIA 4NDOB 2WE4A 4F6TA 2V5HA 2WE5A 4NDRA 2J4JA 1GS5A 2VA1A 2X2WA 2A1FA 2BRXA 2J4KA 3S6GA 3C1NA 2WXBA 3C1MA 4JZ9A 2J0WA 2CDQA 3AAWA 4USJA 3LL9A 4A7XA 4I49A 2J4LA 3QVFA 1E19A 2JI5A 3U6UA 2E9YA 2AKOA 2V4YA 4NDPA 3D2MA 2HMFA 2J0XA 3K4OA 1OHBA 3QVHA 4JZ8A 2OGXA 4NDOA 3KZFA 2BUFA 2IJ9A
chains in the Genus database with same CATH topology
3T7BA 3ZZIA 2JJXA 2R8VA 3ZZFA 3D41A 4AXSA 4OLCA 2AP9A 3LKKA 4A7WA 3QURA 2BNFA 1OH9A 2JJ4A 3D40A 3NWYA 3C20A 2BTYA 4NDQB 3QUNA 4F6TB 3EK5A 3L76A 4NDRB 3AB4A 3ZZHA 3S6HA 4AB7A 1Z9DA 3B8GA 2R98A 4KZTA 3ZZGA 2BRIA 2BNEA 1B7BA 2BMUA 3L86A 2J5VA 1GSJA 4Q1TA 1YBDA 3LL5A 3K56A 3WWNA 4JZ7A 3K4YA 3S6KA 3K52A 3EK6A 2W21A 2BNDA 3D2PA 4NDPB 2RD5A 1OHAA 2J5TA 3QUOA 3AB2A 3WWMA 2OGXB 4NDQA 3TVIA 4NDOB 2WE4A 4F6TA 2V5HA 2WE5A 4NDRA 2J4JA 1GS5A 2VA1A 2X2WA 2A1FA 2BRXA 2J4KA 3S6GA 3C1NA 2WXBA 3C1MA 4JZ9A 2J0WA 2CDQA 3AAWA 4USJA 3LL9A 4A7XA 4I49A 2J4LA 3QVFA 1E19A 2JI5A 3U6UA 2E9YA 2AKOA 2V4YA 4NDPA 3D2MA 2HMFA 2J0XA 3K4OA 1OHBA 3QVHA 4JZ8A 2OGXA 4NDOA 3KZFA 2BUFA 2IJ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T7B A;  3ZZI A;  2JJX A;  2R8V A;  3ZZF A;  3D41 A;  4AXS A;  4OLC A;  2AP9 A;  3LKK A;  4A7W A;  3QUR A;  2BNF A;  1OH9 A;  2JJ4 A;  3D40 A;  3NWY A;  3C20 A;  2BTY A;  4NDQ B;  3QUN A;  4F6T B;  3EK5 A;  3L76 A;  4NDR B;  3AB4 A;  3ZZH A;  3S6H A;  4AB7 A;  1Z9D A;  3B8G A;  2R98 A;  4KZT A;  3ZZG A;  2BRI A;  2BNE A;  1B7B A;  2BMU A;  3L86 A;  2J5V A;  1GSJ A;  4Q1T A;  1YBD A;  3LL5 A;  3K56 A;  3WWN A;  4JZ7 A;  3K4Y A;  3S6K A;  3K52 A;  3EK6 A;  2W21 A;  2BND A;  3D2P A;  4NDP B;  2RD5 A;  1OHA A;  2J5T A;  3QUO A;  3AB2 A;  3WWM A;  2OGX B;  4NDQ A;  3TVI A;  4NDO B;  2WE4 A;  4F6T A;  2V5H A;  2WE5 A;  4NDR A;  2J4J A;  1GS5 A;  2VA1 A;  2X2W A;  2A1F A;  2BRX A;  2J4K A;  3S6G A;  3C1N A;  2WXB A;  3C1M A;  4JZ9 A;  2J0W A;  2CDQ A;  3AAW A;  4USJ A;  3LL9 A;  4A7X A;  4I49 A;  2J4L A;  3QVF A;  1E19 A;  2JI5 A;  3U6U A;  2E9Y A;  2AKO A;  2V4Y A;  4NDP A;  3D2M A;  2HMF A;  2J0X A;  3K4O A;  1OHB A;  3QVH A;  4JZ8 A;  2OGX A;  4NDO A;  3KZF A;  2BUF A;  2IJ9 A; 
#chains in the Genus database with same CATH topology
 3T7B A;  3ZZI A;  2JJX A;  2R8V A;  3ZZF A;  3D41 A;  4AXS A;  4OLC A;  2AP9 A;  3LKK A;  4A7W A;  3QUR A;  2BNF A;  1OH9 A;  2JJ4 A;  3D40 A;  3NWY A;  3C20 A;  2BTY A;  4NDQ B;  3QUN A;  4F6T B;  3EK5 A;  3L76 A;  4NDR B;  3AB4 A;  3ZZH A;  3S6H A;  4AB7 A;  1Z9D A;  3B8G A;  2R98 A;  4KZT A;  3ZZG A;  2BRI A;  2BNE A;  1B7B A;  2BMU A;  3L86 A;  2J5V A;  1GSJ A;  4Q1T A;  1YBD A;  3LL5 A;  3K56 A;  3WWN A;  4JZ7 A;  3K4Y A;  3S6K A;  3K52 A;  3EK6 A;  2W21 A;  2BND A;  3D2P A;  4NDP B;  2RD5 A;  1OHA A;  2J5T A;  3QUO A;  3AB2 A;  3WWM A;  2OGX B;  4NDQ A;  3TVI A;  4NDO B;  2WE4 A;  4F6T A;  2V5H A;  2WE5 A;  4NDR A;  2J4J A;  1GS5 A;  2VA1 A;  2X2W A;  2A1F A;  2BRX A;  2J4K A;  3S6G A;  3C1N A;  2WXB A;  3C1M A;  4JZ9 A;  2J0W A;  2CDQ A;  3AAW A;  4USJ A;  3LL9 A;  4A7X A;  4I49 A;  2J4L A;  3QVF A;  1E19 A;  2JI5 A;  3U6U A;  2E9Y A;  2AKO A;  2V4Y A;  4NDP A;  3D2M A;  2HMF A;  2J0X A;  3K4O A;  1OHB A;  3QVH A;  4JZ8 A;  2OGX A;  4NDO A;  3KZF A;  2BUF A;  2IJ9 A; 
#chains in the Genus database with same CATH homology
 3T7B A;  3ZZI A;  2JJX A;  2R8V A;  3ZZF A;  3D41 A;  4AXS A;  4OLC A;  2AP9 A;  3LKK A;  4A7W A;  3QUR A;  2BNF A;  1OH9 A;  2JJ4 A;  3D40 A;  3NWY A;  3C20 A;  2BTY A;  4NDQ B;  3QUN A;  4F6T B;  3EK5 A;  3L76 A;  4NDR B;  3AB4 A;  3ZZH A;  3S6H A;  4AB7 A;  1Z9D A;  3B8G A;  2R98 A;  4KZT A;  3ZZG A;  2BRI A;  2BNE A;  1B7B A;  2BMU A;  3L86 A;  2J5V A;  1GSJ A;  4Q1T A;  1YBD A;  3LL5 A;  3K56 A;  3WWN A;  4JZ7 A;  3K4Y A;  3S6K A;  3K52 A;  3EK6 A;  2W21 A;  2BND A;  3D2P A;  4NDP B;  2RD5 A;  1OHA A;  2J5T A;  3QUO A;  3AB2 A;  3WWM A;  2OGX B;  4NDQ A;  3TVI A;  4NDO B;  2WE4 A;  4F6T A;  2V5H A;  2WE5 A;  4NDR A;  2J4J A;  1GS5 A;  2VA1 A;  2X2W A;  2A1F A;  2BRX A;  2J4K A;  3S6G A;  3C1N A;  2WXB A;  3C1M A;  4JZ9 A;  2J0W A;  2CDQ A;  3AAW A;  4USJ A;  3LL9 A;  4A7X A;  4I49 A;  2J4L A;  3QVF A;  1E19 A;  2JI5 A;  3U6U A;  2E9Y A;  2AKO A;  2V4Y A;  4NDP A;  3D2M A;  2HMF A;  2J0X A;  3K4O A;  1OHB A;  3QVH A;  4JZ8 A;  2OGX A;  4NDO A;  3KZF A;  2BUF A;  2IJ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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