2J4KA

Crystal structure of uridylate kinase from sulfolobus solfataricus in complex with ump to 2.2 angstrom resolution
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
226
structure length
207
Chain Sequence
MNIILKISGKFFDEDNVDNLIVLRQSIKELADNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRIYADVKLIPHLTTQDLRKILLLDPLAIKIVERSKIRVIVMNYRKLNRIEVSSIIEPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus solfataricus
molecule keywords URIDYLATE KINASE
total genus 68
structure length 207
sequence length 226
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2006-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j4kA00
4NDRA 2CDQA 3K52A 3WWNA 2J4JA 3K56A 3EK5A 4USJA 1E19A 3K4YA 4F6TB 1GSJA 2BNDA 3S6GA 1Z9DA 3LL9A 4NDQB 4OLCA 2WE5A 2JJ4A 2OGXA 2V5HA 2BNEA 2WE4A 2A1FA 4NDOA 4NDPB 3C1MA 2BTYA 2V4YA 4JZ8A 2R8VA 2HMFA 2BRIA 2X2WA 3L76A 3ZZIA 1GS5A 2J0XA 1B7BA 2J0WA 2J5TA 3QURA 3K4OA 2J5VA 3QVHA 3LKKA 3ZZHA 2OGXB 1OHAA 1OH9A 4Q1TA 4JZ9A 4KZTA 3D40A 3LL5A 4NDRB 2AP9A 2VA1A 3T7BA 2RD5A 3QVFA 4F6TA 2BUFA 2J4KA 2W21A 3C1NA 3S6KA 4AB7A 3D2PA 2E9YA 4NDQA 3AB4A 3NWYA 3QUOA 3AAWA 1YBDA 4NDOB 4NDPA 3C20A 3L86A 4A7XA 2IJ9A 3D41A 3KZFA 2R98A 2BNFA 3TVIA 2BMUA 3ZZFA 3U6UA 2J4LA 3B8GA 2JI5A 2JJXA 4A7WA 4AXSA 3D2MA 4JZ7A 3AB2A 2AKOA 3S6HA 3QUNA 3WWMA 2BRXA 3ZZGA 1OHBA 2WXBA 3EK6A 4I49A
chains in the Genus database with same CATH superfamily
4NDRA 2CDQA 3K52A 3WWNA 2J4JA 3K56A 3EK5A 4USJA 1E19A 3K4YA 4F6TB 1GSJA 2BNDA 3S6GA 1Z9DA 3LL9A 4NDQB 4OLCA 2WE5A 2JJ4A 2OGXA 2V5HA 2BNEA 2WE4A 2A1FA 4NDOA 4NDPB 3C1MA 2BTYA 2V4YA 4JZ8A 2R8VA 2HMFA 2BRIA 2X2WA 3L76A 3ZZIA 1GS5A 2J0XA 1B7BA 2J0WA 2J5TA 3QURA 3K4OA 2J5VA 3QVHA 3LKKA 3ZZHA 2OGXB 1OHAA 1OH9A 4Q1TA 4JZ9A 4KZTA 3D40A 3LL5A 4NDRB 2AP9A 2VA1A 3T7BA 2RD5A 3QVFA 4F6TA 2BUFA 2J4KA 2W21A 3C1NA 3S6KA 4AB7A 3D2PA 2E9YA 4NDQA 3AB4A 3NWYA 3QUOA 3AAWA 1YBDA 4NDOB 4NDPA 3C20A 3L86A 4A7XA 2IJ9A 3D41A 3KZFA 2R98A 2BNFA 3TVIA 2BMUA 3ZZFA 3U6UA 2J4LA 3B8GA 2JI5A 2JJXA 4A7WA 4AXSA 3D2MA 4JZ7A 3AB2A 2AKOA 3S6HA 3QUNA 3WWMA 2BRXA 3ZZGA 1OHBA 2WXBA 3EK6A 4I49A
chains in the Genus database with same CATH topology
4NDRA 2CDQA 3K52A 3WWNA 2J4JA 3K56A 3EK5A 4USJA 1E19A 3K4YA 4F6TB 1GSJA 2BNDA 3S6GA 1Z9DA 3LL9A 4NDQB 4OLCA 2WE5A 2JJ4A 2OGXA 2V5HA 2BNEA 2WE4A 2A1FA 4NDOA 4NDPB 3C1MA 2BTYA 2V4YA 4JZ8A 2R8VA 2HMFA 2BRIA 2X2WA 3L76A 3ZZIA 1GS5A 2J0XA 1B7BA 2J0WA 2J5TA 3QURA 3K4OA 2J5VA 3QVHA 3LKKA 3ZZHA 2OGXB 1OHAA 1OH9A 4Q1TA 4JZ9A 4KZTA 3D40A 3LL5A 4NDRB 2AP9A 2VA1A 3T7BA 2RD5A 3QVFA 4F6TA 2BUFA 2J4KA 2W21A 3C1NA 3S6KA 4AB7A 3D2PA 2E9YA 4NDQA 3AB4A 3NWYA 3QUOA 3AAWA 1YBDA 4NDOB 4NDPA 3C20A 3L86A 4A7XA 2IJ9A 3D41A 3KZFA 2R98A 2BNFA 3TVIA 2BMUA 3ZZFA 3U6UA 2J4LA 3B8GA 2JI5A 2JJXA 4A7WA 4AXSA 3D2MA 4JZ7A 3AB2A 2AKOA 3S6HA 3QUNA 3WWMA 2BRXA 3ZZGA 1OHBA 2WXBA 3EK6A 4I49A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NDR A;  2CDQ A;  3K52 A;  3WWN A;  2J4J A;  3K56 A;  3EK5 A;  4USJ A;  1E19 A;  3K4Y A;  4F6T B;  1GSJ A;  2BND A;  3S6G A;  1Z9D A;  3LL9 A;  4NDQ B;  4OLC A;  2WE5 A;  2JJ4 A;  2OGX A;  2V5H A;  2BNE A;  2WE4 A;  2A1F A;  4NDO A;  4NDP B;  3C1M A;  2BTY A;  2V4Y A;  4JZ8 A;  2R8V A;  2HMF A;  2BRI A;  2X2W A;  3L76 A;  3ZZI A;  1GS5 A;  2J0X A;  1B7B A;  2J0W A;  2J5T A;  3QUR A;  3K4O A;  2J5V A;  3QVH A;  3LKK A;  3ZZH A;  2OGX B;  1OHA A;  1OH9 A;  4Q1T A;  4JZ9 A;  4KZT A;  3D40 A;  3LL5 A;  4NDR B;  2AP9 A;  2VA1 A;  3T7B A;  2RD5 A;  3QVF A;  4F6T A;  2BUF A;  2J4K A;  2W21 A;  3C1N A;  3S6K A;  4AB7 A;  3D2P A;  2E9Y A;  4NDQ A;  3AB4 A;  3NWY A;  3QUO A;  3AAW A;  1YBD A;  4NDO B;  4NDP A;  3C20 A;  3L86 A;  4A7X A;  2IJ9 A;  3D41 A;  3KZF A;  2R98 A;  2BNF A;  3TVI A;  2BMU A;  3ZZF A;  3U6U A;  2J4L A;  3B8G A;  2JI5 A;  2JJX A;  4A7W A;  4AXS A;  3D2M A;  4JZ7 A;  3AB2 A;  2AKO A;  3S6H A;  3QUN A;  3WWM A;  2BRX A;  3ZZG A;  1OHB A;  2WXB A;  3EK6 A;  4I49 A; 
#chains in the Genus database with same CATH topology
 4NDR A;  2CDQ A;  3K52 A;  3WWN A;  2J4J A;  3K56 A;  3EK5 A;  4USJ A;  1E19 A;  3K4Y A;  4F6T B;  1GSJ A;  2BND A;  3S6G A;  1Z9D A;  3LL9 A;  4NDQ B;  4OLC A;  2WE5 A;  2JJ4 A;  2OGX A;  2V5H A;  2BNE A;  2WE4 A;  2A1F A;  4NDO A;  4NDP B;  3C1M A;  2BTY A;  2V4Y A;  4JZ8 A;  2R8V A;  2HMF A;  2BRI A;  2X2W A;  3L76 A;  3ZZI A;  1GS5 A;  2J0X A;  1B7B A;  2J0W A;  2J5T A;  3QUR A;  3K4O A;  2J5V A;  3QVH A;  3LKK A;  3ZZH A;  2OGX B;  1OHA A;  1OH9 A;  4Q1T A;  4JZ9 A;  4KZT A;  3D40 A;  3LL5 A;  4NDR B;  2AP9 A;  2VA1 A;  3T7B A;  2RD5 A;  3QVF A;  4F6T A;  2BUF A;  2J4K A;  2W21 A;  3C1N A;  3S6K A;  4AB7 A;  3D2P A;  2E9Y A;  4NDQ A;  3AB4 A;  3NWY A;  3QUO A;  3AAW A;  1YBD A;  4NDO B;  4NDP A;  3C20 A;  3L86 A;  4A7X A;  2IJ9 A;  3D41 A;  3KZF A;  2R98 A;  2BNF A;  3TVI A;  2BMU A;  3ZZF A;  3U6U A;  2J4L A;  3B8G A;  2JI5 A;  2JJX A;  4A7W A;  4AXS A;  3D2M A;  4JZ7 A;  3AB2 A;  2AKO A;  3S6H A;  3QUN A;  3WWM A;  2BRX A;  3ZZG A;  1OHB A;  2WXB A;  3EK6 A;  4I49 A; 
#chains in the Genus database with same CATH homology
 4NDR A;  2CDQ A;  3K52 A;  3WWN A;  2J4J A;  3K56 A;  3EK5 A;  4USJ A;  1E19 A;  3K4Y A;  4F6T B;  1GSJ A;  2BND A;  3S6G A;  1Z9D A;  3LL9 A;  4NDQ B;  4OLC A;  2WE5 A;  2JJ4 A;  2OGX A;  2V5H A;  2BNE A;  2WE4 A;  2A1F A;  4NDO A;  4NDP B;  3C1M A;  2BTY A;  2V4Y A;  4JZ8 A;  2R8V A;  2HMF A;  2BRI A;  2X2W A;  3L76 A;  3ZZI A;  1GS5 A;  2J0X A;  1B7B A;  2J0W A;  2J5T A;  3QUR A;  3K4O A;  2J5V A;  3QVH A;  3LKK A;  3ZZH A;  2OGX B;  1OHA A;  1OH9 A;  4Q1T A;  4JZ9 A;  4KZT A;  3D40 A;  3LL5 A;  4NDR B;  2AP9 A;  2VA1 A;  3T7B A;  2RD5 A;  3QVF A;  4F6T A;  2BUF A;  2J4K A;  2W21 A;  3C1N A;  3S6K A;  4AB7 A;  3D2P A;  2E9Y A;  4NDQ A;  3AB4 A;  3NWY A;  3QUO A;  3AAW A;  1YBD A;  4NDO B;  4NDP A;  3C20 A;  3L86 A;  4A7X A;  2IJ9 A;  3D41 A;  3KZF A;  2R98 A;  2BNF A;  3TVI A;  2BMU A;  3ZZF A;  3U6U A;  2J4L A;  3B8G A;  2JI5 A;  2JJX A;  4A7W A;  4AXS A;  3D2M A;  4JZ7 A;  3AB2 A;  2AKO A;  3S6H A;  3QUN A;  3WWM A;  2BRX A;  3ZZG A;  1OHB A;  2WXB A;  3EK6 A;  4I49 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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