2J4LA

Crystal structure of uridylate kinase from sulfolobus solfataricus in complex with utp to 2.8 angstrom resolution
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
226
structure length
214
Chain Sequence
MNIILKISGKFFDEDNVDNLIVLRQSIKELADNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRIYADVKLIPHLTTQDLRKIELLDPLAIKIVERSKIRVIVMNYRKLNRIIDILKGEEVSSIIEPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus solfataricus
molecule keywords URIDYLATE KINASE
total genus 73
structure length 214
sequence length 226
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2006-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j4lA00
3QVFA 2BTYA 3D2MA 3EK6A 4NDQA 2W21A 4F6TB 3C20A 3QUOA 3LKKA 1GSJA 4A7WA 2J4LA 2VA1A 4NDQB 2WE4A 2JI5A 3U6UA 2J5TA 3K4OA 3ZZIA 2J0WA 4AXSA 2AKOA 2BNDA 2WE5A 3D41A 4JZ7A 3C1NA 4NDPA 3WWNA 2BRIA 3AB2A 2RD5A 3S6KA 2IJ9A 1OHAA 3L86A 2WXBA 3S6GA 1OHBA 3QUNA 2J4JA 4Q1TA 4NDPB 4NDRA 4OLCA 3ZZFA 3B8GA 2HMFA 1YBDA 2J4KA 4JZ9A 2BUFA 4NDOA 4A7XA 4USJA 2E9YA 3QURA 2V5HA 2BNEA 4JZ8A 4NDRB 3EK5A 2BRXA 2BMUA 3D40A 4NDOB 1GS5A 3ZZGA 3QVHA 3AB4A 2J5VA 3KZFA 1Z9DA 3K4YA 3NWYA 2JJ4A 2J0XA 3L76A 3AAWA 2A1FA 3K56A 2BNFA 1OH9A 2OGXA 1E19A 2X2WA 3LL9A 2V4YA 3D2PA 3LL5A 2R8VA 3T7BA 2OGXB 2R98A 2CDQA 2JJXA 3C1MA 3ZZHA 3S6HA 2AP9A 4KZTA 4F6TA 4AB7A 3TVIA 3WWMA 1B7BA 4I49A 3K52A
chains in the Genus database with same CATH superfamily
3QVFA 2BTYA 3D2MA 3EK6A 4NDQA 2W21A 4F6TB 3C20A 3QUOA 3LKKA 1GSJA 4A7WA 2J4LA 2VA1A 4NDQB 2WE4A 2JI5A 3U6UA 2J5TA 3K4OA 3ZZIA 2J0WA 4AXSA 2AKOA 2BNDA 2WE5A 3D41A 4JZ7A 3C1NA 4NDPA 3WWNA 2BRIA 3AB2A 2RD5A 3S6KA 2IJ9A 1OHAA 3L86A 2WXBA 3S6GA 1OHBA 3QUNA 2J4JA 4Q1TA 4NDPB 4NDRA 4OLCA 3ZZFA 3B8GA 2HMFA 1YBDA 2J4KA 4JZ9A 2BUFA 4NDOA 4A7XA 4USJA 2E9YA 3QURA 2V5HA 2BNEA 4JZ8A 4NDRB 3EK5A 2BRXA 2BMUA 3D40A 4NDOB 1GS5A 3ZZGA 3QVHA 3AB4A 2J5VA 3KZFA 1Z9DA 3K4YA 3NWYA 2JJ4A 2J0XA 3L76A 3AAWA 2A1FA 3K56A 2BNFA 1OH9A 2OGXA 1E19A 2X2WA 3LL9A 2V4YA 3D2PA 3LL5A 2R8VA 3T7BA 2OGXB 2R98A 2CDQA 2JJXA 3C1MA 3ZZHA 3S6HA 2AP9A 4KZTA 4F6TA 4AB7A 3TVIA 3WWMA 1B7BA 4I49A 3K52A
chains in the Genus database with same CATH topology
3QVFA 2BTYA 3D2MA 3EK6A 4NDQA 2W21A 4F6TB 3C20A 3QUOA 3LKKA 1GSJA 4A7WA 2J4LA 2VA1A 4NDQB 2WE4A 2JI5A 3U6UA 2J5TA 3K4OA 3ZZIA 2J0WA 4AXSA 2AKOA 2BNDA 2WE5A 3D41A 4JZ7A 3C1NA 4NDPA 3WWNA 2BRIA 3AB2A 2RD5A 3S6KA 2IJ9A 1OHAA 3L86A 2WXBA 3S6GA 1OHBA 3QUNA 2J4JA 4Q1TA 4NDPB 4NDRA 4OLCA 3ZZFA 3B8GA 2HMFA 1YBDA 2J4KA 4JZ9A 2BUFA 4NDOA 4A7XA 4USJA 2E9YA 3QURA 2V5HA 2BNEA 4JZ8A 4NDRB 3EK5A 2BRXA 2BMUA 3D40A 4NDOB 1GS5A 3ZZGA 3QVHA 3AB4A 2J5VA 3KZFA 1Z9DA 3K4YA 3NWYA 2JJ4A 2J0XA 3L76A 3AAWA 2A1FA 3K56A 2BNFA 1OH9A 2OGXA 1E19A 2X2WA 3LL9A 2V4YA 3D2PA 3LL5A 2R8VA 3T7BA 2OGXB 2R98A 2CDQA 2JJXA 3C1MA 3ZZHA 3S6HA 2AP9A 4KZTA 4F6TA 4AB7A 3TVIA 3WWMA 1B7BA 4I49A 3K52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QVF A;  2BTY A;  3D2M A;  3EK6 A;  4NDQ A;  2W21 A;  4F6T B;  3C20 A;  3QUO A;  3LKK A;  1GSJ A;  4A7W A;  2J4L A;  2VA1 A;  4NDQ B;  2WE4 A;  2JI5 A;  3U6U A;  2J5T A;  3K4O A;  3ZZI A;  2J0W A;  4AXS A;  2AKO A;  2BND A;  2WE5 A;  3D41 A;  4JZ7 A;  3C1N A;  4NDP A;  3WWN A;  2BRI A;  3AB2 A;  2RD5 A;  3S6K A;  2IJ9 A;  1OHA A;  3L86 A;  2WXB A;  3S6G A;  1OHB A;  3QUN A;  2J4J A;  4Q1T A;  4NDP B;  4NDR A;  4OLC A;  3ZZF A;  3B8G A;  2HMF A;  1YBD A;  2J4K A;  4JZ9 A;  2BUF A;  4NDO A;  4A7X A;  4USJ A;  2E9Y A;  3QUR A;  2V5H A;  2BNE A;  4JZ8 A;  4NDR B;  3EK5 A;  2BRX A;  2BMU A;  3D40 A;  4NDO B;  1GS5 A;  3ZZG A;  3QVH A;  3AB4 A;  2J5V A;  3KZF A;  1Z9D A;  3K4Y A;  3NWY A;  2JJ4 A;  2J0X A;  3L76 A;  3AAW A;  2A1F A;  3K56 A;  2BNF A;  1OH9 A;  2OGX A;  1E19 A;  2X2W A;  3LL9 A;  2V4Y A;  3D2P A;  3LL5 A;  2R8V A;  3T7B A;  2OGX B;  2R98 A;  2CDQ A;  2JJX A;  3C1M A;  3ZZH A;  3S6H A;  2AP9 A;  4KZT A;  4F6T A;  4AB7 A;  3TVI A;  3WWM A;  1B7B A;  4I49 A;  3K52 A; 
#chains in the Genus database with same CATH topology
 3QVF A;  2BTY A;  3D2M A;  3EK6 A;  4NDQ A;  2W21 A;  4F6T B;  3C20 A;  3QUO A;  3LKK A;  1GSJ A;  4A7W A;  2J4L A;  2VA1 A;  4NDQ B;  2WE4 A;  2JI5 A;  3U6U A;  2J5T A;  3K4O A;  3ZZI A;  2J0W A;  4AXS A;  2AKO A;  2BND A;  2WE5 A;  3D41 A;  4JZ7 A;  3C1N A;  4NDP A;  3WWN A;  2BRI A;  3AB2 A;  2RD5 A;  3S6K A;  2IJ9 A;  1OHA A;  3L86 A;  2WXB A;  3S6G A;  1OHB A;  3QUN A;  2J4J A;  4Q1T A;  4NDP B;  4NDR A;  4OLC A;  3ZZF A;  3B8G A;  2HMF A;  1YBD A;  2J4K A;  4JZ9 A;  2BUF A;  4NDO A;  4A7X A;  4USJ A;  2E9Y A;  3QUR A;  2V5H A;  2BNE A;  4JZ8 A;  4NDR B;  3EK5 A;  2BRX A;  2BMU A;  3D40 A;  4NDO B;  1GS5 A;  3ZZG A;  3QVH A;  3AB4 A;  2J5V A;  3KZF A;  1Z9D A;  3K4Y A;  3NWY A;  2JJ4 A;  2J0X A;  3L76 A;  3AAW A;  2A1F A;  3K56 A;  2BNF A;  1OH9 A;  2OGX A;  1E19 A;  2X2W A;  3LL9 A;  2V4Y A;  3D2P A;  3LL5 A;  2R8V A;  3T7B A;  2OGX B;  2R98 A;  2CDQ A;  2JJX A;  3C1M A;  3ZZH A;  3S6H A;  2AP9 A;  4KZT A;  4F6T A;  4AB7 A;  3TVI A;  3WWM A;  1B7B A;  4I49 A;  3K52 A; 
#chains in the Genus database with same CATH homology
 3QVF A;  2BTY A;  3D2M A;  3EK6 A;  4NDQ A;  2W21 A;  4F6T B;  3C20 A;  3QUO A;  3LKK A;  1GSJ A;  4A7W A;  2J4L A;  2VA1 A;  4NDQ B;  2WE4 A;  2JI5 A;  3U6U A;  2J5T A;  3K4O A;  3ZZI A;  2J0W A;  4AXS A;  2AKO A;  2BND A;  2WE5 A;  3D41 A;  4JZ7 A;  3C1N A;  4NDP A;  3WWN A;  2BRI A;  3AB2 A;  2RD5 A;  3S6K A;  2IJ9 A;  1OHA A;  3L86 A;  2WXB A;  3S6G A;  1OHB A;  3QUN A;  2J4J A;  4Q1T A;  4NDP B;  4NDR A;  4OLC A;  3ZZF A;  3B8G A;  2HMF A;  1YBD A;  2J4K A;  4JZ9 A;  2BUF A;  4NDO A;  4A7X A;  4USJ A;  2E9Y A;  3QUR A;  2V5H A;  2BNE A;  4JZ8 A;  4NDR B;  3EK5 A;  2BRX A;  2BMU A;  3D40 A;  4NDO B;  1GS5 A;  3ZZG A;  3QVH A;  3AB4 A;  2J5V A;  3KZF A;  1Z9D A;  3K4Y A;  3NWY A;  2JJ4 A;  2J0X A;  3L76 A;  3AAW A;  2A1F A;  3K56 A;  2BNF A;  1OH9 A;  2OGX A;  1E19 A;  2X2W A;  3LL9 A;  2V4Y A;  3D2P A;  3LL5 A;  2R8V A;  3T7B A;  2OGX B;  2R98 A;  2CDQ A;  2JJX A;  3C1M A;  3ZZH A;  3S6H A;  2AP9 A;  4KZT A;  4F6T A;  4AB7 A;  3TVI A;  3WWM A;  1B7B A;  4I49 A;  3K52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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