2WE4A

Carbamate kinase from enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
309
structure length
309
Chain Sequence
GKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGDEIVGTVVTK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Enterococcus faecalis
publication title Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site-Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria.
pubmed doi rcsb
molecule keywords CARBAMATE KINASE 1
total genus 105
structure length 309
sequence length 309
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.2: Carbamate kinase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2we4A00
2R98A 4NDQA 3LKKA 2J4LA 3T7BA 3NWYA 2J4JA 4KZTA 3S6KA 3L86A 3ZZHA 4NDRA 2BNDA 3D2MA 3EK5A 2V5HA 2WE5A 2CDQA 2JJ4A 3B8GA 2BTYA 2X2WA 2BRXA 2BNFA 2J0XA 3WWMA 2E9YA 2BRIA 3C1NA 4F6TA 4I49A 3TVIA 2BNEA 4NDPB 1OHBA 1E19A 2AP9A 3K4OA 2AKOA 3KZFA 3QURA 4JZ8A 2RD5A 3AB2A 3LL9A 4NDOB 3S6HA 2BUFA 2OGXA 4NDQB 1Z9DA 3QUNA 1OHAA 3D2PA 4JZ7A 3D41A 4A7XA 1YBDA 4JZ9A 2HMFA 1B7BA 4NDRB 2JJXA 1OH9A 3ZZFA 1GSJA 3AB4A 3S6GA 2BMUA 3QUOA 3D40A 2R8VA 3K52A 2J5VA 4AXSA 2WE4A 4F6TB 4OLCA 2V4YA 4Q1TA 2IJ9A 3C20A 4USJA 4A7WA 3EK6A 2J4KA 3QVFA 3U6UA 2OGXB 1GS5A 3ZZIA 3ZZGA 3WWNA 3LL5A 2A1FA 2WXBA 3K4YA 2VA1A 2W21A 4NDPA 2JI5A 3AAWA 2J0WA 3K56A 3L76A 3C1MA 3QVHA 2J5TA 4AB7A 4NDOA
chains in the Genus database with same CATH superfamily
2R98A 4NDQA 3LKKA 2J4LA 3T7BA 3NWYA 2J4JA 4KZTA 3S6KA 3L86A 3ZZHA 4NDRA 2BNDA 3D2MA 3EK5A 2V5HA 2WE5A 2CDQA 2JJ4A 3B8GA 2BTYA 2X2WA 2BRXA 2BNFA 2J0XA 3WWMA 2E9YA 2BRIA 3C1NA 4F6TA 4I49A 3TVIA 2BNEA 4NDPB 1OHBA 1E19A 2AP9A 3K4OA 2AKOA 3KZFA 3QURA 4JZ8A 2RD5A 3AB2A 3LL9A 4NDOB 3S6HA 2BUFA 2OGXA 4NDQB 1Z9DA 3QUNA 1OHAA 3D2PA 4JZ7A 3D41A 4A7XA 1YBDA 4JZ9A 2HMFA 1B7BA 4NDRB 2JJXA 1OH9A 3ZZFA 1GSJA 3AB4A 3S6GA 2BMUA 3QUOA 3D40A 2R8VA 3K52A 2J5VA 4AXSA 2WE4A 4F6TB 4OLCA 2V4YA 4Q1TA 2IJ9A 3C20A 4USJA 4A7WA 3EK6A 2J4KA 3QVFA 3U6UA 2OGXB 1GS5A 3ZZIA 3ZZGA 3WWNA 3LL5A 2A1FA 2WXBA 3K4YA 2VA1A 2W21A 4NDPA 2JI5A 3AAWA 2J0WA 3K56A 3L76A 3C1MA 3QVHA 2J5TA 4AB7A 4NDOA
chains in the Genus database with same CATH topology
2R98A 4NDQA 3LKKA 2J4LA 3T7BA 3NWYA 2J4JA 4KZTA 3S6KA 3L86A 3ZZHA 4NDRA 2BNDA 3D2MA 3EK5A 2V5HA 2WE5A 2CDQA 2JJ4A 3B8GA 2BTYA 2X2WA 2BRXA 2BNFA 2J0XA 3WWMA 2E9YA 2BRIA 3C1NA 4F6TA 4I49A 3TVIA 2BNEA 4NDPB 1OHBA 1E19A 2AP9A 3K4OA 2AKOA 3KZFA 3QURA 4JZ8A 2RD5A 3AB2A 3LL9A 4NDOB 3S6HA 2BUFA 2OGXA 4NDQB 1Z9DA 3QUNA 1OHAA 3D2PA 4JZ7A 3D41A 4A7XA 1YBDA 4JZ9A 2HMFA 1B7BA 4NDRB 2JJXA 1OH9A 3ZZFA 1GSJA 3AB4A 3S6GA 2BMUA 3QUOA 3D40A 2R8VA 3K52A 2J5VA 4AXSA 2WE4A 4F6TB 4OLCA 2V4YA 4Q1TA 2IJ9A 3C20A 4USJA 4A7WA 3EK6A 2J4KA 3QVFA 3U6UA 2OGXB 1GS5A 3ZZIA 3ZZGA 3WWNA 3LL5A 2A1FA 2WXBA 3K4YA 2VA1A 2W21A 4NDPA 2JI5A 3AAWA 2J0WA 3K56A 3L76A 3C1MA 3QVHA 2J5TA 4AB7A 4NDOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R98 A;  4NDQ A;  3LKK A;  2J4L A;  3T7B A;  3NWY A;  2J4J A;  4KZT A;  3S6K A;  3L86 A;  3ZZH A;  4NDR A;  2BND A;  3D2M A;  3EK5 A;  2V5H A;  2WE5 A;  2CDQ A;  2JJ4 A;  3B8G A;  2BTY A;  2X2W A;  2BRX A;  2BNF A;  2J0X A;  3WWM A;  2E9Y A;  2BRI A;  3C1N A;  4F6T A;  4I49 A;  3TVI A;  2BNE A;  4NDP B;  1OHB A;  1E19 A;  2AP9 A;  3K4O A;  2AKO A;  3KZF A;  3QUR A;  4JZ8 A;  2RD5 A;  3AB2 A;  3LL9 A;  4NDO B;  3S6H A;  2BUF A;  2OGX A;  4NDQ B;  1Z9D A;  3QUN A;  1OHA A;  3D2P A;  4JZ7 A;  3D41 A;  4A7X A;  1YBD A;  4JZ9 A;  2HMF A;  1B7B A;  4NDR B;  2JJX A;  1OH9 A;  3ZZF A;  1GSJ A;  3AB4 A;  3S6G A;  2BMU A;  3QUO A;  3D40 A;  2R8V A;  3K52 A;  2J5V A;  4AXS A;  2WE4 A;  4F6T B;  4OLC A;  2V4Y A;  4Q1T A;  2IJ9 A;  3C20 A;  4USJ A;  4A7W A;  3EK6 A;  2J4K A;  3QVF A;  3U6U A;  2OGX B;  1GS5 A;  3ZZI A;  3ZZG A;  3WWN A;  3LL5 A;  2A1F A;  2WXB A;  3K4Y A;  2VA1 A;  2W21 A;  4NDP A;  2JI5 A;  3AAW A;  2J0W A;  3K56 A;  3L76 A;  3C1M A;  3QVH A;  2J5T A;  4AB7 A;  4NDO A; 
#chains in the Genus database with same CATH topology
 2R98 A;  4NDQ A;  3LKK A;  2J4L A;  3T7B A;  3NWY A;  2J4J A;  4KZT A;  3S6K A;  3L86 A;  3ZZH A;  4NDR A;  2BND A;  3D2M A;  3EK5 A;  2V5H A;  2WE5 A;  2CDQ A;  2JJ4 A;  3B8G A;  2BTY A;  2X2W A;  2BRX A;  2BNF A;  2J0X A;  3WWM A;  2E9Y A;  2BRI A;  3C1N A;  4F6T A;  4I49 A;  3TVI A;  2BNE A;  4NDP B;  1OHB A;  1E19 A;  2AP9 A;  3K4O A;  2AKO A;  3KZF A;  3QUR A;  4JZ8 A;  2RD5 A;  3AB2 A;  3LL9 A;  4NDO B;  3S6H A;  2BUF A;  2OGX A;  4NDQ B;  1Z9D A;  3QUN A;  1OHA A;  3D2P A;  4JZ7 A;  3D41 A;  4A7X A;  1YBD A;  4JZ9 A;  2HMF A;  1B7B A;  4NDR B;  2JJX A;  1OH9 A;  3ZZF A;  1GSJ A;  3AB4 A;  3S6G A;  2BMU A;  3QUO A;  3D40 A;  2R8V A;  3K52 A;  2J5V A;  4AXS A;  2WE4 A;  4F6T B;  4OLC A;  2V4Y A;  4Q1T A;  2IJ9 A;  3C20 A;  4USJ A;  4A7W A;  3EK6 A;  2J4K A;  3QVF A;  3U6U A;  2OGX B;  1GS5 A;  3ZZI A;  3ZZG A;  3WWN A;  3LL5 A;  2A1F A;  2WXB A;  3K4Y A;  2VA1 A;  2W21 A;  4NDP A;  2JI5 A;  3AAW A;  2J0W A;  3K56 A;  3L76 A;  3C1M A;  3QVH A;  2J5T A;  4AB7 A;  4NDO A; 
#chains in the Genus database with same CATH homology
 2R98 A;  4NDQ A;  3LKK A;  2J4L A;  3T7B A;  3NWY A;  2J4J A;  4KZT A;  3S6K A;  3L86 A;  3ZZH A;  4NDR A;  2BND A;  3D2M A;  3EK5 A;  2V5H A;  2WE5 A;  2CDQ A;  2JJ4 A;  3B8G A;  2BTY A;  2X2W A;  2BRX A;  2BNF A;  2J0X A;  3WWM A;  2E9Y A;  2BRI A;  3C1N A;  4F6T A;  4I49 A;  3TVI A;  2BNE A;  4NDP B;  1OHB A;  1E19 A;  2AP9 A;  3K4O A;  2AKO A;  3KZF A;  3QUR A;  4JZ8 A;  2RD5 A;  3AB2 A;  3LL9 A;  4NDO B;  3S6H A;  2BUF A;  2OGX A;  4NDQ B;  1Z9D A;  3QUN A;  1OHA A;  3D2P A;  4JZ7 A;  3D41 A;  4A7X A;  1YBD A;  4JZ9 A;  2HMF A;  1B7B A;  4NDR B;  2JJX A;  1OH9 A;  3ZZF A;  1GSJ A;  3AB4 A;  3S6G A;  2BMU A;  3QUO A;  3D40 A;  2R8V A;  3K52 A;  2J5V A;  4AXS A;  2WE4 A;  4F6T B;  4OLC A;  2V4Y A;  4Q1T A;  2IJ9 A;  3C20 A;  4USJ A;  4A7W A;  3EK6 A;  2J4K A;  3QVF A;  3U6U A;  2OGX B;  1GS5 A;  3ZZI A;  3ZZG A;  3WWN A;  3LL5 A;  2A1F A;  2WXB A;  3K4Y A;  2VA1 A;  2W21 A;  4NDP A;  2JI5 A;  3AAW A;  2J0W A;  3K56 A;  3L76 A;  3C1M A;  3QVH A;  2J5T A;  4AB7 A;  4NDO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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