3L76A

Crystal structure of aspartate kinase from synechocystis
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
599
structure length
585
Chain Sequence
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALLSLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSLVGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAIAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALSNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVDALKAAHSAFNLAGTKTVTVPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
pubmed doi rcsb
molecule tags Transferase
source organism Synechocystis
molecule keywords Aspartokinase
total genus 176
structure length 585
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3l76A01
1OHAA 2AP9A 3K4YA 4KZTA 4NDPA 3KZFA 3T7BA 1E19A 3QUNA 2A1FA 4NDOA 2WXBA 3LKKA 1YBDA 3AAWA 2E9YA 3D2PA 3D41A 3EK6A 3AB2A 2BTYA 3WWNA 2BRXA 2V5HA 2J5TA 2JI5A 3NWYA 3LL5A 3C1NA 3QUOA 2W21A 4NDRB 3EK5A 3B8GA 2OGXB 4NDQB 2J4LA 2R98A 1GSJA 2RD5A 3WWMA 2VA1A 4USJA 4JZ9A 4JZ8A 3ZZFA 4F6TB 3S6HA 2BNEA 2WE4A 3K52A 3L76A 1Z9DA 2WE5A 1B7BA 3TVIA 4AB7A 2JJXA 3S6GA 4F6TA 3K56A 4I49A 3S6KA 4AXSA 4A7XA 2V4YA 4OLCA 2JJ4A 2BMUA 3D40A 2BRIA 1GS5A 4JZ7A 4NDRA 2OGXA 4NDQA 3AB4A 2BNFA 3ZZIA 2J4KA 3D2MA 4NDPB 2HMFA 3U6UA 3ZZHA 3K4OA 2J4JA 4NDOB 3C20A 2X2WA 4A7WA 2J0WA 3C1MA 2IJ9A 2J0XA 2BUFA 3QVHA 2AKOA 3QURA 2BNDA 2CDQA 2R8VA 3LL9A 3L86A 3ZZGA 4Q1TA 3QVFA 1OHBA 2J5VA 1OH9A
chains in the Genus database with same CATH superfamily
1OHAA 2AP9A 3K4YA 4KZTA 4NDPA 3KZFA 3T7BA 1E19A 3QUNA 2A1FA 4NDOA 2WXBA 3LKKA 1YBDA 3AAWA 2E9YA 3D2PA 3D41A 3EK6A 3AB2A 2BTYA 3WWNA 2BRXA 2V5HA 2J5TA 2JI5A 3NWYA 3LL5A 3C1NA 3QUOA 2W21A 4NDRB 3EK5A 3B8GA 2OGXB 4NDQB 2J4LA 2R98A 1GSJA 2RD5A 3WWMA 2VA1A 4USJA 4JZ9A 4JZ8A 3ZZFA 4F6TB 3S6HA 2BNEA 2WE4A 3K52A 3L76A 1Z9DA 2WE5A 1B7BA 3TVIA 4AB7A 2JJXA 3S6GA 4F6TA 3K56A 4I49A 3S6KA 4AXSA 4A7XA 2V4YA 4OLCA 2JJ4A 2BMUA 3D40A 2BRIA 1GS5A 4JZ7A 4NDRA 2OGXA 4NDQA 3AB4A 2BNFA 3ZZIA 2J4KA 3D2MA 4NDPB 2HMFA 3U6UA 3ZZHA 3K4OA 2J4JA 4NDOB 3C20A 2X2WA 4A7WA 2J0WA 3C1MA 2IJ9A 2J0XA 2BUFA 3QVHA 2AKOA 3QURA 2BNDA 2CDQA 2R8VA 3LL9A 3L86A 3ZZGA 4Q1TA 3QVFA 1OHBA 2J5VA 1OH9A
chains in the Genus database with same CATH topology
1OHAA 2AP9A 3K4YA 4KZTA 4NDPA 3KZFA 3T7BA 1E19A 3QUNA 2A1FA 4NDOA 2WXBA 3LKKA 1YBDA 3AAWA 2E9YA 3D2PA 3D41A 3EK6A 3AB2A 2BTYA 3WWNA 2BRXA 2V5HA 2J5TA 2JI5A 3NWYA 3LL5A 3C1NA 3QUOA 2W21A 4NDRB 3EK5A 3B8GA 2OGXB 4NDQB 2J4LA 2R98A 1GSJA 2RD5A 3WWMA 2VA1A 4USJA 4JZ9A 4JZ8A 3ZZFA 4F6TB 3S6HA 2BNEA 2WE4A 3K52A 3L76A 1Z9DA 2WE5A 1B7BA 3TVIA 4AB7A 2JJXA 3S6GA 4F6TA 3K56A 4I49A 3S6KA 4AXSA 4A7XA 2V4YA 4OLCA 2JJ4A 2BMUA 3D40A 2BRIA 1GS5A 4JZ7A 4NDRA 2OGXA 4NDQA 3AB4A 2BNFA 3ZZIA 2J4KA 3D2MA 4NDPB 2HMFA 3U6UA 3ZZHA 3K4OA 2J4JA 4NDOB 3C20A 2X2WA 4A7WA 2J0WA 3C1MA 2IJ9A 2J0XA 2BUFA 3QVHA 2AKOA 3QURA 2BNDA 2CDQA 2R8VA 3LL9A 3L86A 3ZZGA 4Q1TA 3QVFA 1OHBA 2J5VA 1OH9A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1OHA A;  2AP9 A;  3K4Y A;  4KZT A;  4NDP A;  3KZF A;  3T7B A;  1E19 A;  3QUN A;  2A1F A;  4NDO A;  2WXB A;  3LKK A;  1YBD A;  3AAW A;  2E9Y A;  3D2P A;  3D41 A;  3EK6 A;  3AB2 A;  2BTY A;  3WWN A;  2BRX A;  2V5H A;  2J5T A;  2JI5 A;  3NWY A;  3LL5 A;  3C1N A;  3QUO A;  2W21 A;  4NDR B;  3EK5 A;  3B8G A;  2OGX B;  4NDQ B;  2J4L A;  2R98 A;  1GSJ A;  2RD5 A;  3WWM A;  2VA1 A;  4USJ A;  4JZ9 A;  4JZ8 A;  3ZZF A;  4F6T B;  3S6H A;  2BNE A;  2WE4 A;  3K52 A;  3L76 A;  1Z9D A;  2WE5 A;  1B7B A;  3TVI A;  4AB7 A;  2JJX A;  3S6G A;  4F6T A;  3K56 A;  4I49 A;  3S6K A;  4AXS A;  4A7X A;  2V4Y A;  4OLC A;  2JJ4 A;  2BMU A;  3D40 A;  2BRI A;  1GS5 A;  4JZ7 A;  4NDR A;  2OGX A;  4NDQ A;  3AB4 A;  2BNF A;  3ZZI A;  2J4K A;  3D2M A;  4NDP B;  2HMF A;  3U6U A;  3ZZH A;  3K4O A;  2J4J A;  4NDO B;  3C20 A;  2X2W A;  4A7W A;  2J0W A;  3C1M A;  2IJ9 A;  2J0X A;  2BUF A;  3QVH A;  2AKO A;  3QUR A;  2BND A;  2CDQ A;  2R8V A;  3LL9 A;  3L86 A;  3ZZG A;  4Q1T A;  3QVF A;  1OHB A;  2J5V A;  1OH9 A; 
#chains in the Genus database with same CATH topology
 1OHA A;  2AP9 A;  3K4Y A;  4KZT A;  4NDP A;  3KZF A;  3T7B A;  1E19 A;  3QUN A;  2A1F A;  4NDO A;  2WXB A;  3LKK A;  1YBD A;  3AAW A;  2E9Y A;  3D2P A;  3D41 A;  3EK6 A;  3AB2 A;  2BTY A;  3WWN A;  2BRX A;  2V5H A;  2J5T A;  2JI5 A;  3NWY A;  3LL5 A;  3C1N A;  3QUO A;  2W21 A;  4NDR B;  3EK5 A;  3B8G A;  2OGX B;  4NDQ B;  2J4L A;  2R98 A;  1GSJ A;  2RD5 A;  3WWM A;  2VA1 A;  4USJ A;  4JZ9 A;  4JZ8 A;  3ZZF A;  4F6T B;  3S6H A;  2BNE A;  2WE4 A;  3K52 A;  3L76 A;  1Z9D A;  2WE5 A;  1B7B A;  3TVI A;  4AB7 A;  2JJX A;  3S6G A;  4F6T A;  3K56 A;  4I49 A;  3S6K A;  4AXS A;  4A7X A;  2V4Y A;  4OLC A;  2JJ4 A;  2BMU A;  3D40 A;  2BRI A;  1GS5 A;  4JZ7 A;  4NDR A;  2OGX A;  4NDQ A;  3AB4 A;  2BNF A;  3ZZI A;  2J4K A;  3D2M A;  4NDP B;  2HMF A;  3U6U A;  3ZZH A;  3K4O A;  2J4J A;  4NDO B;  3C20 A;  2X2W A;  4A7W A;  2J0W A;  3C1M A;  2IJ9 A;  2J0X A;  2BUF A;  3QVH A;  2AKO A;  3QUR A;  2BND A;  2CDQ A;  2R8V A;  3LL9 A;  3L86 A;  3ZZG A;  4Q1T A;  3QVF A;  1OHB A;  2J5V A;  1OH9 A; 
#chains in the Genus database with same CATH homology
 1OHA A;  2AP9 A;  3K4Y A;  4KZT A;  4NDP A;  3KZF A;  3T7B A;  1E19 A;  3QUN A;  2A1F A;  4NDO A;  2WXB A;  3LKK A;  1YBD A;  3AAW A;  2E9Y A;  3D2P A;  3D41 A;  3EK6 A;  3AB2 A;  2BTY A;  3WWN A;  2BRX A;  2V5H A;  2J5T A;  2JI5 A;  3NWY A;  3LL5 A;  3C1N A;  3QUO A;  2W21 A;  4NDR B;  3EK5 A;  3B8G A;  2OGX B;  4NDQ B;  2J4L A;  2R98 A;  1GSJ A;  2RD5 A;  3WWM A;  2VA1 A;  4USJ A;  4JZ9 A;  4JZ8 A;  3ZZF A;  4F6T B;  3S6H A;  2BNE A;  2WE4 A;  3K52 A;  3L76 A;  1Z9D A;  2WE5 A;  1B7B A;  3TVI A;  4AB7 A;  2JJX A;  3S6G A;  4F6T A;  3K56 A;  4I49 A;  3S6K A;  4AXS A;  4A7X A;  2V4Y A;  4OLC A;  2JJ4 A;  2BMU A;  3D40 A;  2BRI A;  1GS5 A;  4JZ7 A;  4NDR A;  2OGX A;  4NDQ A;  3AB4 A;  2BNF A;  3ZZI A;  2J4K A;  3D2M A;  4NDP B;  2HMF A;  3U6U A;  3ZZH A;  3K4O A;  2J4J A;  4NDO B;  3C20 A;  2X2W A;  4A7W A;  2J0W A;  3C1M A;  2IJ9 A;  2J0X A;  2BUF A;  3QVH A;  2AKO A;  3QUR A;  2BND A;  2CDQ A;  2R8V A;  3LL9 A;  3L86 A;  3ZZG A;  4Q1T A;  3QVF A;  1OHB A;  2J5V A;  1OH9 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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