3NWYA

Structure and allosteric regulation of the uridine monophosphate kinase from mycobacterium tuberculosis
Total Genus 73
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
235
structure length
227
Chain Sequence
LSGYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFAQLQQLGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVFAEPEAELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLLTDGNIARAVRGEKIGTLVTT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.
pubmed doi rcsb
molecule keywords Uridylate kinase
molecule tags Transferase
source organism Mycobacterium tuberculosis
total genus 73
structure length 227
sequence length 235
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2010-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3nwyA00
1GS5A 1E19A 3C1MA 2VA1A 2A1FA 2J0WA 4NDOB 1YBDA 2BNDA 4NDRA 2OGXA 2X2WA 3AB4A 1OHAA 2AP9A 2BNFA 4JZ9A 2BUFA 2BRIA 2J4JA 3AAWA 2E9YA 4AXSA 3ZZFA 3ZZIA 2BMUA 4NDPB 2J5VA 4KZTA 4Q1TA 3LL5A 2V5HA 3QUOA 2J5TA 2W21A 3K4OA 3S6KA 3K4YA 3C1NA 4F6TA 4A7WA 3EK6A 4NDQA 2J0XA 1Z9DA 3KZFA 3ZZGA 3S6GA 2BRXA 3S6HA 2OGXB 2V4YA 2HMFA 2JJ4A 2AKOA 1OHBA 3QVHA 4JZ7A 4NDOA 3WWNA 1GSJA 3U6UA 3D41A 2WE5A 2WXBA 4A7XA 3TVIA 3K52A 3EK5A 3QUNA 2J4LA 3D2MA 4F6TB 3B8GA 2BNEA 2CDQA 4NDRB 3L86A 3NWYA 4NDPA 3L76A 2WE4A 3K56A 3LKKA 3QURA 2IJ9A 2R8VA 3C20A 4USJA 3D40A 3D2PA 3T7BA 1B7BA 3LL9A 2RD5A 2JI5A 4JZ8A 2R98A 2J4KA 3ZZHA 3WWMA 4OLCA 4I49A 2JJXA 3AB2A 4AB7A 1OH9A 3QVFA 4NDQB 2BTYA
chains in the Genus database with same CATH superfamily
1GS5A 1E19A 3C1MA 2VA1A 2A1FA 2J0WA 4NDOB 1YBDA 2BNDA 4NDRA 2OGXA 2X2WA 3AB4A 1OHAA 2AP9A 2BNFA 4JZ9A 2BUFA 2BRIA 2J4JA 3AAWA 2E9YA 4AXSA 3ZZFA 3ZZIA 2BMUA 4NDPB 2J5VA 4KZTA 4Q1TA 3LL5A 2V5HA 3QUOA 2J5TA 2W21A 3K4OA 3S6KA 3K4YA 3C1NA 4F6TA 4A7WA 3EK6A 4NDQA 2J0XA 1Z9DA 3KZFA 3ZZGA 3S6GA 2BRXA 3S6HA 2OGXB 2V4YA 2HMFA 2JJ4A 2AKOA 1OHBA 3QVHA 4JZ7A 4NDOA 3WWNA 1GSJA 3U6UA 3D41A 2WE5A 2WXBA 4A7XA 3TVIA 3K52A 3EK5A 3QUNA 2J4LA 3D2MA 4F6TB 3B8GA 2BNEA 2CDQA 4NDRB 3L86A 3NWYA 4NDPA 3L76A 2WE4A 3K56A 3LKKA 3QURA 2IJ9A 2R8VA 3C20A 4USJA 3D40A 3D2PA 3T7BA 1B7BA 3LL9A 2RD5A 2JI5A 4JZ8A 2R98A 2J4KA 3ZZHA 3WWMA 4OLCA 4I49A 2JJXA 3AB2A 4AB7A 1OH9A 3QVFA 4NDQB 2BTYA
chains in the Genus database with same CATH topology
1GS5A 1E19A 3C1MA 2VA1A 2A1FA 2J0WA 4NDOB 1YBDA 2BNDA 4NDRA 2OGXA 2X2WA 3AB4A 1OHAA 2AP9A 2BNFA 4JZ9A 2BUFA 2BRIA 2J4JA 3AAWA 2E9YA 4AXSA 3ZZFA 3ZZIA 2BMUA 4NDPB 2J5VA 4KZTA 4Q1TA 3LL5A 2V5HA 3QUOA 2J5TA 2W21A 3K4OA 3S6KA 3K4YA 3C1NA 4F6TA 4A7WA 3EK6A 4NDQA 2J0XA 1Z9DA 3KZFA 3ZZGA 3S6GA 2BRXA 3S6HA 2OGXB 2V4YA 2HMFA 2JJ4A 2AKOA 1OHBA 3QVHA 4JZ7A 4NDOA 3WWNA 1GSJA 3U6UA 3D41A 2WE5A 2WXBA 4A7XA 3TVIA 3K52A 3EK5A 3QUNA 2J4LA 3D2MA 4F6TB 3B8GA 2BNEA 2CDQA 4NDRB 3L86A 3NWYA 4NDPA 3L76A 2WE4A 3K56A 3LKKA 3QURA 2IJ9A 2R8VA 3C20A 4USJA 3D40A 3D2PA 3T7BA 1B7BA 3LL9A 2RD5A 2JI5A 4JZ8A 2R98A 2J4KA 3ZZHA 3WWMA 4OLCA 4I49A 2JJXA 3AB2A 4AB7A 1OH9A 3QVFA 4NDQB 2BTYA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1GS5 A;  1E19 A;  3C1M A;  2VA1 A;  2A1F A;  2J0W A;  4NDO B;  1YBD A;  2BND A;  4NDR A;  2OGX A;  2X2W A;  3AB4 A;  1OHA A;  2AP9 A;  2BNF A;  4JZ9 A;  2BUF A;  2BRI A;  2J4J A;  3AAW A;  2E9Y A;  4AXS A;  3ZZF A;  3ZZI A;  2BMU A;  4NDP B;  2J5V A;  4KZT A;  4Q1T A;  3LL5 A;  2V5H A;  3QUO A;  2J5T A;  2W21 A;  3K4O A;  3S6K A;  3K4Y A;  3C1N A;  4F6T A;  4A7W A;  3EK6 A;  4NDQ A;  2J0X A;  1Z9D A;  3KZF A;  3ZZG A;  3S6G A;  2BRX A;  3S6H A;  2OGX B;  2V4Y A;  2HMF A;  2JJ4 A;  2AKO A;  1OHB A;  3QVH A;  4JZ7 A;  4NDO A;  3WWN A;  1GSJ A;  3U6U A;  3D41 A;  2WE5 A;  2WXB A;  4A7X A;  3TVI A;  3K52 A;  3EK5 A;  3QUN A;  2J4L A;  3D2M A;  4F6T B;  3B8G A;  2BNE A;  2CDQ A;  4NDR B;  3L86 A;  3NWY A;  4NDP A;  3L76 A;  2WE4 A;  3K56 A;  3LKK A;  3QUR A;  2IJ9 A;  2R8V A;  3C20 A;  4USJ A;  3D40 A;  3D2P A;  3T7B A;  1B7B A;  3LL9 A;  2RD5 A;  2JI5 A;  4JZ8 A;  2R98 A;  2J4K A;  3ZZH A;  3WWM A;  4OLC A;  4I49 A;  2JJX A;  3AB2 A;  4AB7 A;  1OH9 A;  3QVF A;  4NDQ B;  2BTY A; 
#chains in the Genus database with same CATH topology
 1GS5 A;  1E19 A;  3C1M A;  2VA1 A;  2A1F A;  2J0W A;  4NDO B;  1YBD A;  2BND A;  4NDR A;  2OGX A;  2X2W A;  3AB4 A;  1OHA A;  2AP9 A;  2BNF A;  4JZ9 A;  2BUF A;  2BRI A;  2J4J A;  3AAW A;  2E9Y A;  4AXS A;  3ZZF A;  3ZZI A;  2BMU A;  4NDP B;  2J5V A;  4KZT A;  4Q1T A;  3LL5 A;  2V5H A;  3QUO A;  2J5T A;  2W21 A;  3K4O A;  3S6K A;  3K4Y A;  3C1N A;  4F6T A;  4A7W A;  3EK6 A;  4NDQ A;  2J0X A;  1Z9D A;  3KZF A;  3ZZG A;  3S6G A;  2BRX A;  3S6H A;  2OGX B;  2V4Y A;  2HMF A;  2JJ4 A;  2AKO A;  1OHB A;  3QVH A;  4JZ7 A;  4NDO A;  3WWN A;  1GSJ A;  3U6U A;  3D41 A;  2WE5 A;  2WXB A;  4A7X A;  3TVI A;  3K52 A;  3EK5 A;  3QUN A;  2J4L A;  3D2M A;  4F6T B;  3B8G A;  2BNE A;  2CDQ A;  4NDR B;  3L86 A;  3NWY A;  4NDP A;  3L76 A;  2WE4 A;  3K56 A;  3LKK A;  3QUR A;  2IJ9 A;  2R8V A;  3C20 A;  4USJ A;  3D40 A;  3D2P A;  3T7B A;  1B7B A;  3LL9 A;  2RD5 A;  2JI5 A;  4JZ8 A;  2R98 A;  2J4K A;  3ZZH A;  3WWM A;  4OLC A;  4I49 A;  2JJX A;  3AB2 A;  4AB7 A;  1OH9 A;  3QVF A;  4NDQ B;  2BTY A; 
#chains in the Genus database with same CATH homology
 1GS5 A;  1E19 A;  3C1M A;  2VA1 A;  2A1F A;  2J0W A;  4NDO B;  1YBD A;  2BND A;  4NDR A;  2OGX A;  2X2W A;  3AB4 A;  1OHA A;  2AP9 A;  2BNF A;  4JZ9 A;  2BUF A;  2BRI A;  2J4J A;  3AAW A;  2E9Y A;  4AXS A;  3ZZF A;  3ZZI A;  2BMU A;  4NDP B;  2J5V A;  4KZT A;  4Q1T A;  3LL5 A;  2V5H A;  3QUO A;  2J5T A;  2W21 A;  3K4O A;  3S6K A;  3K4Y A;  3C1N A;  4F6T A;  4A7W A;  3EK6 A;  4NDQ A;  2J0X A;  1Z9D A;  3KZF A;  3ZZG A;  3S6G A;  2BRX A;  3S6H A;  2OGX B;  2V4Y A;  2HMF A;  2JJ4 A;  2AKO A;  1OHB A;  3QVH A;  4JZ7 A;  4NDO A;  3WWN A;  1GSJ A;  3U6U A;  3D41 A;  2WE5 A;  2WXB A;  4A7X A;  3TVI A;  3K52 A;  3EK5 A;  3QUN A;  2J4L A;  3D2M A;  4F6T B;  3B8G A;  2BNE A;  2CDQ A;  4NDR B;  3L86 A;  3NWY A;  4NDP A;  3L76 A;  2WE4 A;  3K56 A;  3LKK A;  3QUR A;  2IJ9 A;  2R8V A;  3C20 A;  4USJ A;  3D40 A;  3D2P A;  3T7B A;  1B7B A;  3LL9 A;  2RD5 A;  2JI5 A;  4JZ8 A;  2R98 A;  2J4K A;  3ZZH A;  3WWM A;  4OLC A;  4I49 A;  2JJX A;  3AB2 A;  4AB7 A;  1OH9 A;  3QVF A;  4NDQ B;  2BTY A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite