3QUNA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with mgatp
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
271
structure length
247
Chain Sequence
SGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGDTILPEVDARSPEQAYAALWGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule tags Transferase
source organism Streptomyces wedmorensis
molecule keywords FomA protein
total genus 68
structure length 247
sequence length 271
ec nomenclature
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qunA00
3EK5A 2J5TA 4JZ9A 2X2WA 4A7XA 4NDQA 4USJA 2BNFA 3L86A 3D41A 3K4OA 3D40A 3QUOA 2JI5A 3QUNA 2BNEA 4NDRA 2J0WA 3QVHA 4JZ8A 3AB4A 2V5HA 2V4YA 1OH9A 2J4JA 2BMUA 3D2MA 3S6KA 4AB7A 2CDQA 4NDQB 3S6GA 3ZZFA 3QURA 1E19A 3AB2A 4NDRB 4AXSA 3S6HA 2BTYA 1YBDA 2OGXB 3K4YA 2BNDA 2A1FA 3C1MA 3KZFA 4Q1TA 4JZ7A 2J4KA 1B7BA 1Z9DA 3ZZGA 2OGXA 3B8GA 4NDOA 3WWNA 2BUFA 3EK6A 3QVFA 4A7WA 3AAWA 2AP9A 1OHAA 2R98A 3LL5A 2J0XA 2WXBA 3LKKA 2BRXA 4NDPB 3K52A 3LL9A 3ZZHA 4NDOB 4F6TA 1GSJA 2WE4A 4OLCA 1GS5A 4NDPA 2E9YA 3D2PA 2JJXA 2JJ4A 2IJ9A 3ZZIA 1OHBA 3K56A 2BRIA 4F6TB 3C1NA 3T7BA 3TVIA 2VA1A 2HMFA 2W21A 2AKOA 3L76A 2J4LA 4KZTA 4I49A 2R8VA 3C20A 2RD5A 2WE5A 2J5VA 3WWMA 3NWYA 3U6UA
chains in the Genus database with same CATH superfamily
3EK5A 2J5TA 4JZ9A 2X2WA 4A7XA 4NDQA 4USJA 2BNFA 3L86A 3D41A 3K4OA 3D40A 3QUOA 2JI5A 3QUNA 2BNEA 4NDRA 2J0WA 3QVHA 4JZ8A 3AB4A 2V5HA 2V4YA 1OH9A 2J4JA 2BMUA 3D2MA 3S6KA 4AB7A 2CDQA 4NDQB 3S6GA 3ZZFA 3QURA 1E19A 3AB2A 4NDRB 4AXSA 3S6HA 2BTYA 1YBDA 2OGXB 3K4YA 2BNDA 2A1FA 3C1MA 3KZFA 4Q1TA 4JZ7A 2J4KA 1B7BA 1Z9DA 3ZZGA 2OGXA 3B8GA 4NDOA 3WWNA 2BUFA 3EK6A 3QVFA 4A7WA 3AAWA 2AP9A 1OHAA 2R98A 3LL5A 2J0XA 2WXBA 3LKKA 2BRXA 4NDPB 3K52A 3LL9A 3ZZHA 4NDOB 4F6TA 1GSJA 2WE4A 4OLCA 1GS5A 4NDPA 2E9YA 3D2PA 2JJXA 2JJ4A 2IJ9A 3ZZIA 1OHBA 3K56A 2BRIA 4F6TB 3C1NA 3T7BA 3TVIA 2VA1A 2HMFA 2W21A 2AKOA 3L76A 2J4LA 4KZTA 4I49A 2R8VA 3C20A 2RD5A 2WE5A 2J5VA 3WWMA 3NWYA 3U6UA
chains in the Genus database with same CATH topology
3EK5A 2J5TA 4JZ9A 2X2WA 4A7XA 4NDQA 4USJA 2BNFA 3L86A 3D41A 3K4OA 3D40A 3QUOA 2JI5A 3QUNA 2BNEA 4NDRA 2J0WA 3QVHA 4JZ8A 3AB4A 2V5HA 2V4YA 1OH9A 2J4JA 2BMUA 3D2MA 3S6KA 4AB7A 2CDQA 4NDQB 3S6GA 3ZZFA 3QURA 1E19A 3AB2A 4NDRB 4AXSA 3S6HA 2BTYA 1YBDA 2OGXB 3K4YA 2BNDA 2A1FA 3C1MA 3KZFA 4Q1TA 4JZ7A 2J4KA 1B7BA 1Z9DA 3ZZGA 2OGXA 3B8GA 4NDOA 3WWNA 2BUFA 3EK6A 3QVFA 4A7WA 3AAWA 2AP9A 1OHAA 2R98A 3LL5A 2J0XA 2WXBA 3LKKA 2BRXA 4NDPB 3K52A 3LL9A 3ZZHA 4NDOB 4F6TA 1GSJA 2WE4A 4OLCA 1GS5A 4NDPA 2E9YA 3D2PA 2JJXA 2JJ4A 2IJ9A 3ZZIA 1OHBA 3K56A 2BRIA 4F6TB 3C1NA 3T7BA 3TVIA 2VA1A 2HMFA 2W21A 2AKOA 3L76A 2J4LA 4KZTA 4I49A 2R8VA 3C20A 2RD5A 2WE5A 2J5VA 3WWMA 3NWYA 3U6UA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3EK5 A;  2J5T A;  4JZ9 A;  2X2W A;  4A7X A;  4NDQ A;  4USJ A;  2BNF A;  3L86 A;  3D41 A;  3K4O A;  3D40 A;  3QUO A;  2JI5 A;  3QUN A;  2BNE A;  4NDR A;  2J0W A;  3QVH A;  4JZ8 A;  3AB4 A;  2V5H A;  2V4Y A;  1OH9 A;  2J4J A;  2BMU A;  3D2M A;  3S6K A;  4AB7 A;  2CDQ A;  4NDQ B;  3S6G A;  3ZZF A;  3QUR A;  1E19 A;  3AB2 A;  4NDR B;  4AXS A;  3S6H A;  2BTY A;  1YBD A;  2OGX B;  3K4Y A;  2BND A;  2A1F A;  3C1M A;  3KZF A;  4Q1T A;  4JZ7 A;  2J4K A;  1B7B A;  1Z9D A;  3ZZG A;  2OGX A;  3B8G A;  4NDO A;  3WWN A;  2BUF A;  3EK6 A;  3QVF A;  4A7W A;  3AAW A;  2AP9 A;  1OHA A;  2R98 A;  3LL5 A;  2J0X A;  2WXB A;  3LKK A;  2BRX A;  4NDP B;  3K52 A;  3LL9 A;  3ZZH A;  4NDO B;  4F6T A;  1GSJ A;  2WE4 A;  4OLC A;  1GS5 A;  4NDP A;  2E9Y A;  3D2P A;  2JJX A;  2JJ4 A;  2IJ9 A;  3ZZI A;  1OHB A;  3K56 A;  2BRI A;  4F6T B;  3C1N A;  3T7B A;  3TVI A;  2VA1 A;  2HMF A;  2W21 A;  2AKO A;  3L76 A;  2J4L A;  4KZT A;  4I49 A;  2R8V A;  3C20 A;  2RD5 A;  2WE5 A;  2J5V A;  3WWM A;  3NWY A;  3U6U A; 
#chains in the Genus database with same CATH topology
 3EK5 A;  2J5T A;  4JZ9 A;  2X2W A;  4A7X A;  4NDQ A;  4USJ A;  2BNF A;  3L86 A;  3D41 A;  3K4O A;  3D40 A;  3QUO A;  2JI5 A;  3QUN A;  2BNE A;  4NDR A;  2J0W A;  3QVH A;  4JZ8 A;  3AB4 A;  2V5H A;  2V4Y A;  1OH9 A;  2J4J A;  2BMU A;  3D2M A;  3S6K A;  4AB7 A;  2CDQ A;  4NDQ B;  3S6G A;  3ZZF A;  3QUR A;  1E19 A;  3AB2 A;  4NDR B;  4AXS A;  3S6H A;  2BTY A;  1YBD A;  2OGX B;  3K4Y A;  2BND A;  2A1F A;  3C1M A;  3KZF A;  4Q1T A;  4JZ7 A;  2J4K A;  1B7B A;  1Z9D A;  3ZZG A;  2OGX A;  3B8G A;  4NDO A;  3WWN A;  2BUF A;  3EK6 A;  3QVF A;  4A7W A;  3AAW A;  2AP9 A;  1OHA A;  2R98 A;  3LL5 A;  2J0X A;  2WXB A;  3LKK A;  2BRX A;  4NDP B;  3K52 A;  3LL9 A;  3ZZH A;  4NDO B;  4F6T A;  1GSJ A;  2WE4 A;  4OLC A;  1GS5 A;  4NDP A;  2E9Y A;  3D2P A;  2JJX A;  2JJ4 A;  2IJ9 A;  3ZZI A;  1OHB A;  3K56 A;  2BRI A;  4F6T B;  3C1N A;  3T7B A;  3TVI A;  2VA1 A;  2HMF A;  2W21 A;  2AKO A;  3L76 A;  2J4L A;  4KZT A;  4I49 A;  2R8V A;  3C20 A;  2RD5 A;  2WE5 A;  2J5V A;  3WWM A;  3NWY A;  3U6U A; 
#chains in the Genus database with same CATH homology
 3EK5 A;  2J5T A;  4JZ9 A;  2X2W A;  4A7X A;  4NDQ A;  4USJ A;  2BNF A;  3L86 A;  3D41 A;  3K4O A;  3D40 A;  3QUO A;  2JI5 A;  3QUN A;  2BNE A;  4NDR A;  2J0W A;  3QVH A;  4JZ8 A;  3AB4 A;  2V5H A;  2V4Y A;  1OH9 A;  2J4J A;  2BMU A;  3D2M A;  3S6K A;  4AB7 A;  2CDQ A;  4NDQ B;  3S6G A;  3ZZF A;  3QUR A;  1E19 A;  3AB2 A;  4NDR B;  4AXS A;  3S6H A;  2BTY A;  1YBD A;  2OGX B;  3K4Y A;  2BND A;  2A1F A;  3C1M A;  3KZF A;  4Q1T A;  4JZ7 A;  2J4K A;  1B7B A;  1Z9D A;  3ZZG A;  2OGX A;  3B8G A;  4NDO A;  3WWN A;  2BUF A;  3EK6 A;  3QVF A;  4A7W A;  3AAW A;  2AP9 A;  1OHA A;  2R98 A;  3LL5 A;  2J0X A;  2WXB A;  3LKK A;  2BRX A;  4NDP B;  3K52 A;  3LL9 A;  3ZZH A;  4NDO B;  4F6T A;  1GSJ A;  2WE4 A;  4OLC A;  1GS5 A;  4NDP A;  2E9Y A;  3D2P A;  2JJX A;  2JJ4 A;  2IJ9 A;  3ZZI A;  1OHB A;  3K56 A;  2BRI A;  4F6T B;  3C1N A;  3T7B A;  3TVI A;  2VA1 A;  2HMF A;  2W21 A;  2AKO A;  3L76 A;  2J4L A;  4KZT A;  4I49 A;  2R8V A;  3C20 A;  2RD5 A;  2WE5 A;  2J5V A;  3WWM A;  3NWY A;  3U6U A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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