3QVFA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with mgadp and fosfomycin vanadate
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
274
structure length
274
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSSEWDATGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule tags Transferase
source organism Streptomyces wedmorensis
molecule keywords FomA protein
total genus 84
structure length 274
sequence length 274
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvfA00
3WWNA 2BNEA 3B8GA 2V5HA 1B7BA 2IJ9A 3D2MA 4Q1TA 3S6GA 2BNFA 2BNDA 3D41A 2BTYA 2WE4A 2BRXA 1OHAA 1OH9A 2BUFA 3C20A 2VA1A 4NDOB 2WE5A 3LL9A 2J0XA 3D2PA 2AKOA 3D40A 3AAWA 2BRIA 2J5VA 3KZFA 4JZ8A 2J4JA 2JJ4A 2E9YA 3LKKA 4JZ7A 2X2WA 2J4KA 2V4YA 3AB4A 4AXSA 2AP9A 2WXBA 2J5TA 3ZZIA 1GSJA 3ZZHA 1OHBA 3EK5A 2W21A 3C1NA 2CDQA 3AB2A 4F6TB 3QUNA 4F6TA 1YBDA 4A7WA 3EK6A 3K4YA 3TVIA 3WWMA 2R8VA 3K56A 4OLCA 3ZZGA 3NWYA 2J4LA 4KZTA 3U6UA 4AB7A 3C1MA 2JI5A 4NDPB 4USJA 4NDPA 1GS5A 3K52A 3QUOA 2OGXB 3S6KA 4NDQB 2RD5A 2OGXA 4NDQA 3L76A 4JZ9A 3QVHA 3ZZFA 3S6HA 3T7BA 3LL5A 3L86A 3K4OA 2BMUA 4NDRB 1E19A 4NDRA 2HMFA 4NDOA 2JJXA 3QURA 1Z9DA 2A1FA 3QVFA 4A7XA 2J0WA 4I49A 2R98A
chains in the Genus database with same CATH superfamily
3WWNA 2BNEA 3B8GA 2V5HA 1B7BA 2IJ9A 3D2MA 4Q1TA 3S6GA 2BNFA 2BNDA 3D41A 2BTYA 2WE4A 2BRXA 1OHAA 1OH9A 2BUFA 3C20A 2VA1A 4NDOB 2WE5A 3LL9A 2J0XA 3D2PA 2AKOA 3D40A 3AAWA 2BRIA 2J5VA 3KZFA 4JZ8A 2J4JA 2JJ4A 2E9YA 3LKKA 4JZ7A 2X2WA 2J4KA 2V4YA 3AB4A 4AXSA 2AP9A 2WXBA 2J5TA 3ZZIA 1GSJA 3ZZHA 1OHBA 3EK5A 2W21A 3C1NA 2CDQA 3AB2A 4F6TB 3QUNA 4F6TA 1YBDA 4A7WA 3EK6A 3K4YA 3TVIA 3WWMA 2R8VA 3K56A 4OLCA 3ZZGA 3NWYA 2J4LA 4KZTA 3U6UA 4AB7A 3C1MA 2JI5A 4NDPB 4USJA 4NDPA 1GS5A 3K52A 3QUOA 2OGXB 3S6KA 4NDQB 2RD5A 2OGXA 4NDQA 3L76A 4JZ9A 3QVHA 3ZZFA 3S6HA 3T7BA 3LL5A 3L86A 3K4OA 2BMUA 4NDRB 1E19A 4NDRA 2HMFA 4NDOA 2JJXA 3QURA 1Z9DA 2A1FA 3QVFA 4A7XA 2J0WA 4I49A 2R98A
chains in the Genus database with same CATH topology
3WWNA 2BNEA 3B8GA 2V5HA 1B7BA 2IJ9A 3D2MA 4Q1TA 3S6GA 2BNFA 2BNDA 3D41A 2BTYA 2WE4A 2BRXA 1OHAA 1OH9A 2BUFA 3C20A 2VA1A 4NDOB 2WE5A 3LL9A 2J0XA 3D2PA 2AKOA 3D40A 3AAWA 2BRIA 2J5VA 3KZFA 4JZ8A 2J4JA 2JJ4A 2E9YA 3LKKA 4JZ7A 2X2WA 2J4KA 2V4YA 3AB4A 4AXSA 2AP9A 2WXBA 2J5TA 3ZZIA 1GSJA 3ZZHA 1OHBA 3EK5A 2W21A 3C1NA 2CDQA 3AB2A 4F6TB 3QUNA 4F6TA 1YBDA 4A7WA 3EK6A 3K4YA 3TVIA 3WWMA 2R8VA 3K56A 4OLCA 3ZZGA 3NWYA 2J4LA 4KZTA 3U6UA 4AB7A 3C1MA 2JI5A 4NDPB 4USJA 4NDPA 1GS5A 3K52A 3QUOA 2OGXB 3S6KA 4NDQB 2RD5A 2OGXA 4NDQA 3L76A 4JZ9A 3QVHA 3ZZFA 3S6HA 3T7BA 3LL5A 3L86A 3K4OA 2BMUA 4NDRB 1E19A 4NDRA 2HMFA 4NDOA 2JJXA 3QURA 1Z9DA 2A1FA 3QVFA 4A7XA 2J0WA 4I49A 2R98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WWN A;  2BNE A;  3B8G A;  2V5H A;  1B7B A;  2IJ9 A;  3D2M A;  4Q1T A;  3S6G A;  2BNF A;  2BND A;  3D41 A;  2BTY A;  2WE4 A;  2BRX A;  1OHA A;  1OH9 A;  2BUF A;  3C20 A;  2VA1 A;  4NDO B;  2WE5 A;  3LL9 A;  2J0X A;  3D2P A;  2AKO A;  3D40 A;  3AAW A;  2BRI A;  2J5V A;  3KZF A;  4JZ8 A;  2J4J A;  2JJ4 A;  2E9Y A;  3LKK A;  4JZ7 A;  2X2W A;  2J4K A;  2V4Y A;  3AB4 A;  4AXS A;  2AP9 A;  2WXB A;  2J5T A;  3ZZI A;  1GSJ A;  3ZZH A;  1OHB A;  3EK5 A;  2W21 A;  3C1N A;  2CDQ A;  3AB2 A;  4F6T B;  3QUN A;  4F6T A;  1YBD A;  4A7W A;  3EK6 A;  3K4Y A;  3TVI A;  3WWM A;  2R8V A;  3K56 A;  4OLC A;  3ZZG A;  3NWY A;  2J4L A;  4KZT A;  3U6U A;  4AB7 A;  3C1M A;  2JI5 A;  4NDP B;  4USJ A;  4NDP A;  1GS5 A;  3K52 A;  3QUO A;  2OGX B;  3S6K A;  4NDQ B;  2RD5 A;  2OGX A;  4NDQ A;  3L76 A;  4JZ9 A;  3QVH A;  3ZZF A;  3S6H A;  3T7B A;  3LL5 A;  3L86 A;  3K4O A;  2BMU A;  4NDR B;  1E19 A;  4NDR A;  2HMF A;  4NDO A;  2JJX A;  3QUR A;  1Z9D A;  2A1F A;  3QVF A;  4A7X A;  2J0W A;  4I49 A;  2R98 A; 
#chains in the Genus database with same CATH topology
 3WWN A;  2BNE A;  3B8G A;  2V5H A;  1B7B A;  2IJ9 A;  3D2M A;  4Q1T A;  3S6G A;  2BNF A;  2BND A;  3D41 A;  2BTY A;  2WE4 A;  2BRX A;  1OHA A;  1OH9 A;  2BUF A;  3C20 A;  2VA1 A;  4NDO B;  2WE5 A;  3LL9 A;  2J0X A;  3D2P A;  2AKO A;  3D40 A;  3AAW A;  2BRI A;  2J5V A;  3KZF A;  4JZ8 A;  2J4J A;  2JJ4 A;  2E9Y A;  3LKK A;  4JZ7 A;  2X2W A;  2J4K A;  2V4Y A;  3AB4 A;  4AXS A;  2AP9 A;  2WXB A;  2J5T A;  3ZZI A;  1GSJ A;  3ZZH A;  1OHB A;  3EK5 A;  2W21 A;  3C1N A;  2CDQ A;  3AB2 A;  4F6T B;  3QUN A;  4F6T A;  1YBD A;  4A7W A;  3EK6 A;  3K4Y A;  3TVI A;  3WWM A;  2R8V A;  3K56 A;  4OLC A;  3ZZG A;  3NWY A;  2J4L A;  4KZT A;  3U6U A;  4AB7 A;  3C1M A;  2JI5 A;  4NDP B;  4USJ A;  4NDP A;  1GS5 A;  3K52 A;  3QUO A;  2OGX B;  3S6K A;  4NDQ B;  2RD5 A;  2OGX A;  4NDQ A;  3L76 A;  4JZ9 A;  3QVH A;  3ZZF A;  3S6H A;  3T7B A;  3LL5 A;  3L86 A;  3K4O A;  2BMU A;  4NDR B;  1E19 A;  4NDR A;  2HMF A;  4NDO A;  2JJX A;  3QUR A;  1Z9D A;  2A1F A;  3QVF A;  4A7X A;  2J0W A;  4I49 A;  2R98 A; 
#chains in the Genus database with same CATH homology
 3WWN A;  2BNE A;  3B8G A;  2V5H A;  1B7B A;  2IJ9 A;  3D2M A;  4Q1T A;  3S6G A;  2BNF A;  2BND A;  3D41 A;  2BTY A;  2WE4 A;  2BRX A;  1OHA A;  1OH9 A;  2BUF A;  3C20 A;  2VA1 A;  4NDO B;  2WE5 A;  3LL9 A;  2J0X A;  3D2P A;  2AKO A;  3D40 A;  3AAW A;  2BRI A;  2J5V A;  3KZF A;  4JZ8 A;  2J4J A;  2JJ4 A;  2E9Y A;  3LKK A;  4JZ7 A;  2X2W A;  2J4K A;  2V4Y A;  3AB4 A;  4AXS A;  2AP9 A;  2WXB A;  2J5T A;  3ZZI A;  1GSJ A;  3ZZH A;  1OHB A;  3EK5 A;  2W21 A;  3C1N A;  2CDQ A;  3AB2 A;  4F6T B;  3QUN A;  4F6T A;  1YBD A;  4A7W A;  3EK6 A;  3K4Y A;  3TVI A;  3WWM A;  2R8V A;  3K56 A;  4OLC A;  3ZZG A;  3NWY A;  2J4L A;  4KZT A;  3U6U A;  4AB7 A;  3C1M A;  2JI5 A;  4NDP B;  4USJ A;  4NDP A;  1GS5 A;  3K52 A;  3QUO A;  2OGX B;  3S6K A;  4NDQ B;  2RD5 A;  2OGX A;  4NDQ A;  3L76 A;  4JZ9 A;  3QVH A;  3ZZF A;  3S6H A;  3T7B A;  3LL5 A;  3L86 A;  3K4O A;  2BMU A;  4NDR B;  1E19 A;  4NDR A;  2HMF A;  4NDO A;  2JJX A;  3QUR A;  1Z9D A;  2A1F A;  3QVF A;  4A7X A;  2J0W A;  4I49 A;  2R98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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