3QVHA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with adp
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
271
structure length
260
Chain Sequence
SGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule keywords FomA protein
molecule tags Transferase
source organism Streptomyces wedmorensis
total genus 79
structure length 260
sequence length 271
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvhA00
2JI5A 2X2WA 4F6TB 2AKOA 3K4OA 4KZTA 3EK5A 3AB2A 2J5VA 2RD5A 3S6KA 1E19A 3ZZIA 3C20A 3D40A 2A1FA 4Q1TA 4A7WA 2OGXB 4NDRA 4A7XA 1OH9A 3U6UA 2R8VA 2V5HA 3B8GA 2V4YA 3LL5A 3C1MA 2J4LA 2HMFA 2J5TA 2J4JA 4NDPA 4NDQB 3AAWA 3QUOA 2JJXA 2JJ4A 4I49A 3QVHA 3QUNA 4F6TA 1YBDA 3K4YA 1B7BA 2WXBA 2BNDA 3QVFA 3ZZFA 2BRXA 2BTYA 2WE5A 2OGXA 2WE4A 4AXSA 3AB4A 1GSJA 2J0XA 3LKKA 4JZ8A 3KZFA 3EK6A 4NDOA 3L76A 3T7BA 2E9YA 1GS5A 3L86A 3TVIA 2BRIA 4NDQA 3ZZHA 3QURA 2J4KA 2W21A 2IJ9A 3C1NA 4NDPB 2R98A 3D2PA 3S6HA 3WWMA 2CDQA 3D2MA 3LL9A 4OLCA 4AB7A 4JZ9A 4USJA 2BNEA 2BMUA 3WWNA 2BNFA 3ZZGA 1Z9DA 2AP9A 3D41A 2BUFA 3S6GA 4NDRB 2J0WA 3NWYA 3K52A 4JZ7A 2VA1A 4NDOB 1OHAA 1OHBA 3K56A
chains in the Genus database with same CATH superfamily
2JI5A 2X2WA 4F6TB 2AKOA 3K4OA 4KZTA 3EK5A 3AB2A 2J5VA 2RD5A 3S6KA 1E19A 3ZZIA 3C20A 3D40A 2A1FA 4Q1TA 4A7WA 2OGXB 4NDRA 4A7XA 1OH9A 3U6UA 2R8VA 2V5HA 3B8GA 2V4YA 3LL5A 3C1MA 2J4LA 2HMFA 2J5TA 2J4JA 4NDPA 4NDQB 3AAWA 3QUOA 2JJXA 2JJ4A 4I49A 3QVHA 3QUNA 4F6TA 1YBDA 3K4YA 1B7BA 2WXBA 2BNDA 3QVFA 3ZZFA 2BRXA 2BTYA 2WE5A 2OGXA 2WE4A 4AXSA 3AB4A 1GSJA 2J0XA 3LKKA 4JZ8A 3KZFA 3EK6A 4NDOA 3L76A 3T7BA 2E9YA 1GS5A 3L86A 3TVIA 2BRIA 4NDQA 3ZZHA 3QURA 2J4KA 2W21A 2IJ9A 3C1NA 4NDPB 2R98A 3D2PA 3S6HA 3WWMA 2CDQA 3D2MA 3LL9A 4OLCA 4AB7A 4JZ9A 4USJA 2BNEA 2BMUA 3WWNA 2BNFA 3ZZGA 1Z9DA 2AP9A 3D41A 2BUFA 3S6GA 4NDRB 2J0WA 3NWYA 3K52A 4JZ7A 2VA1A 4NDOB 1OHAA 1OHBA 3K56A
chains in the Genus database with same CATH topology
2JI5A 2X2WA 4F6TB 2AKOA 3K4OA 4KZTA 3EK5A 3AB2A 2J5VA 2RD5A 3S6KA 1E19A 3ZZIA 3C20A 3D40A 2A1FA 4Q1TA 4A7WA 2OGXB 4NDRA 4A7XA 1OH9A 3U6UA 2R8VA 2V5HA 3B8GA 2V4YA 3LL5A 3C1MA 2J4LA 2HMFA 2J5TA 2J4JA 4NDPA 4NDQB 3AAWA 3QUOA 2JJXA 2JJ4A 4I49A 3QVHA 3QUNA 4F6TA 1YBDA 3K4YA 1B7BA 2WXBA 2BNDA 3QVFA 3ZZFA 2BRXA 2BTYA 2WE5A 2OGXA 2WE4A 4AXSA 3AB4A 1GSJA 2J0XA 3LKKA 4JZ8A 3KZFA 3EK6A 4NDOA 3L76A 3T7BA 2E9YA 1GS5A 3L86A 3TVIA 2BRIA 4NDQA 3ZZHA 3QURA 2J4KA 2W21A 2IJ9A 3C1NA 4NDPB 2R98A 3D2PA 3S6HA 3WWMA 2CDQA 3D2MA 3LL9A 4OLCA 4AB7A 4JZ9A 4USJA 2BNEA 2BMUA 3WWNA 2BNFA 3ZZGA 1Z9DA 2AP9A 3D41A 2BUFA 3S6GA 4NDRB 2J0WA 3NWYA 3K52A 4JZ7A 2VA1A 4NDOB 1OHAA 1OHBA 3K56A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2JI5 A;  2X2W A;  4F6T B;  2AKO A;  3K4O A;  4KZT A;  3EK5 A;  3AB2 A;  2J5V A;  2RD5 A;  3S6K A;  1E19 A;  3ZZI A;  3C20 A;  3D40 A;  2A1F A;  4Q1T A;  4A7W A;  2OGX B;  4NDR A;  4A7X A;  1OH9 A;  3U6U A;  2R8V A;  2V5H A;  3B8G A;  2V4Y A;  3LL5 A;  3C1M A;  2J4L A;  2HMF A;  2J5T A;  2J4J A;  4NDP A;  4NDQ B;  3AAW A;  3QUO A;  2JJX A;  2JJ4 A;  4I49 A;  3QVH A;  3QUN A;  4F6T A;  1YBD A;  3K4Y A;  1B7B A;  2WXB A;  2BND A;  3QVF A;  3ZZF A;  2BRX A;  2BTY A;  2WE5 A;  2OGX A;  2WE4 A;  4AXS A;  3AB4 A;  1GSJ A;  2J0X A;  3LKK A;  4JZ8 A;  3KZF A;  3EK6 A;  4NDO A;  3L76 A;  3T7B A;  2E9Y A;  1GS5 A;  3L86 A;  3TVI A;  2BRI A;  4NDQ A;  3ZZH A;  3QUR A;  2J4K A;  2W21 A;  2IJ9 A;  3C1N A;  4NDP B;  2R98 A;  3D2P A;  3S6H A;  3WWM A;  2CDQ A;  3D2M A;  3LL9 A;  4OLC A;  4AB7 A;  4JZ9 A;  4USJ A;  2BNE A;  2BMU A;  3WWN A;  2BNF A;  3ZZG A;  1Z9D A;  2AP9 A;  3D41 A;  2BUF A;  3S6G A;  4NDR B;  2J0W A;  3NWY A;  3K52 A;  4JZ7 A;  2VA1 A;  4NDO B;  1OHA A;  1OHB A;  3K56 A; 
#chains in the Genus database with same CATH topology
 2JI5 A;  2X2W A;  4F6T B;  2AKO A;  3K4O A;  4KZT A;  3EK5 A;  3AB2 A;  2J5V A;  2RD5 A;  3S6K A;  1E19 A;  3ZZI A;  3C20 A;  3D40 A;  2A1F A;  4Q1T A;  4A7W A;  2OGX B;  4NDR A;  4A7X A;  1OH9 A;  3U6U A;  2R8V A;  2V5H A;  3B8G A;  2V4Y A;  3LL5 A;  3C1M A;  2J4L A;  2HMF A;  2J5T A;  2J4J A;  4NDP A;  4NDQ B;  3AAW A;  3QUO A;  2JJX A;  2JJ4 A;  4I49 A;  3QVH A;  3QUN A;  4F6T A;  1YBD A;  3K4Y A;  1B7B A;  2WXB A;  2BND A;  3QVF A;  3ZZF A;  2BRX A;  2BTY A;  2WE5 A;  2OGX A;  2WE4 A;  4AXS A;  3AB4 A;  1GSJ A;  2J0X A;  3LKK A;  4JZ8 A;  3KZF A;  3EK6 A;  4NDO A;  3L76 A;  3T7B A;  2E9Y A;  1GS5 A;  3L86 A;  3TVI A;  2BRI A;  4NDQ A;  3ZZH A;  3QUR A;  2J4K A;  2W21 A;  2IJ9 A;  3C1N A;  4NDP B;  2R98 A;  3D2P A;  3S6H A;  3WWM A;  2CDQ A;  3D2M A;  3LL9 A;  4OLC A;  4AB7 A;  4JZ9 A;  4USJ A;  2BNE A;  2BMU A;  3WWN A;  2BNF A;  3ZZG A;  1Z9D A;  2AP9 A;  3D41 A;  2BUF A;  3S6G A;  4NDR B;  2J0W A;  3NWY A;  3K52 A;  4JZ7 A;  2VA1 A;  4NDO B;  1OHA A;  1OHB A;  3K56 A; 
#chains in the Genus database with same CATH homology
 2JI5 A;  2X2W A;  4F6T B;  2AKO A;  3K4O A;  4KZT A;  3EK5 A;  3AB2 A;  2J5V A;  2RD5 A;  3S6K A;  1E19 A;  3ZZI A;  3C20 A;  3D40 A;  2A1F A;  4Q1T A;  4A7W A;  2OGX B;  4NDR A;  4A7X A;  1OH9 A;  3U6U A;  2R8V A;  2V5H A;  3B8G A;  2V4Y A;  3LL5 A;  3C1M A;  2J4L A;  2HMF A;  2J5T A;  2J4J A;  4NDP A;  4NDQ B;  3AAW A;  3QUO A;  2JJX A;  2JJ4 A;  4I49 A;  3QVH A;  3QUN A;  4F6T A;  1YBD A;  3K4Y A;  1B7B A;  2WXB A;  2BND A;  3QVF A;  3ZZF A;  2BRX A;  2BTY A;  2WE5 A;  2OGX A;  2WE4 A;  4AXS A;  3AB4 A;  1GSJ A;  2J0X A;  3LKK A;  4JZ8 A;  3KZF A;  3EK6 A;  4NDO A;  3L76 A;  3T7B A;  2E9Y A;  1GS5 A;  3L86 A;  3TVI A;  2BRI A;  4NDQ A;  3ZZH A;  3QUR A;  2J4K A;  2W21 A;  2IJ9 A;  3C1N A;  4NDP B;  2R98 A;  3D2P A;  3S6H A;  3WWM A;  2CDQ A;  3D2M A;  3LL9 A;  4OLC A;  4AB7 A;  4JZ9 A;  4USJ A;  2BNE A;  2BMU A;  3WWN A;  2BNF A;  3ZZG A;  1Z9D A;  2AP9 A;  3D41 A;  2BUF A;  3S6G A;  4NDR B;  2J0W A;  3NWY A;  3K52 A;  4JZ7 A;  2VA1 A;  4NDO B;  1OHA A;  1OHB A;  3K56 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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