3QVHA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with adp
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
271
structure length
260
Chain Sequence
SGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule tags Transferase
source organism Streptomyces wedmorensis
molecule keywords FomA protein
total genus 79
structure length 260
sequence length 271
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvhA00
1GSJA 3C20A 2OGXA 3D2PA 3TVIA 4AXSA 4A7XA 2E9YA 3K4YA 2J0XA 2J4JA 4OLCA 2J5VA 3EK5A 2J4LA 2J4KA 4USJA 2IJ9A 2BMUA 2BNFA 2R98A 3EK6A 3LL5A 3D2MA 4F6TA 4I49A 1YBDA 1Z9DA 1B7BA 2X2WA 3AB4A 3K56A 2VA1A 3L76A 4NDOA 2BUFA 4AB7A 1OH9A 3D41A 4NDPA 1GS5A 3S6HA 4NDOB 4KZTA 2AP9A 3QUNA 1OHBA 2OGXB 2BTYA 4NDQA 2R8VA 2AKOA 3U6UA 2V5HA 2CDQA 3KZFA 3T7BA 4F6TB 4A7WA 2BRXA 3AAWA 2JI5A 3WWMA 2BRIA 3S6GA 2BNEA 3WWNA 1E19A 2W21A 2BNDA 4JZ8A 2J5TA 4JZ7A 3ZZGA 2HMFA 3QVFA 4NDPB 3C1MA 3LL9A 1OHAA 4Q1TA 3L86A 3S6KA 2J0WA 3B8GA 3K52A 4NDRA 2WE4A 2V4YA 2JJXA 3C1NA 2WXBA 4NDQB 2RD5A 2JJ4A 3ZZHA 3ZZFA 3ZZIA 2A1FA 4NDRB 3K4OA 3QURA 3NWYA 3AB2A 2WE5A 4JZ9A 3D40A 3LKKA 3QUOA 3QVHA
chains in the Genus database with same CATH superfamily
1GSJA 3C20A 2OGXA 3D2PA 3TVIA 4AXSA 4A7XA 2E9YA 3K4YA 2J0XA 2J4JA 4OLCA 2J5VA 3EK5A 2J4LA 2J4KA 4USJA 2IJ9A 2BMUA 2BNFA 2R98A 3EK6A 3LL5A 3D2MA 4F6TA 4I49A 1YBDA 1Z9DA 1B7BA 2X2WA 3AB4A 3K56A 2VA1A 3L76A 4NDOA 2BUFA 4AB7A 1OH9A 3D41A 4NDPA 1GS5A 3S6HA 4NDOB 4KZTA 2AP9A 3QUNA 1OHBA 2OGXB 2BTYA 4NDQA 2R8VA 2AKOA 3U6UA 2V5HA 2CDQA 3KZFA 3T7BA 4F6TB 4A7WA 2BRXA 3AAWA 2JI5A 3WWMA 2BRIA 3S6GA 2BNEA 3WWNA 1E19A 2W21A 2BNDA 4JZ8A 2J5TA 4JZ7A 3ZZGA 2HMFA 3QVFA 4NDPB 3C1MA 3LL9A 1OHAA 4Q1TA 3L86A 3S6KA 2J0WA 3B8GA 3K52A 4NDRA 2WE4A 2V4YA 2JJXA 3C1NA 2WXBA 4NDQB 2RD5A 2JJ4A 3ZZHA 3ZZFA 3ZZIA 2A1FA 4NDRB 3K4OA 3QURA 3NWYA 3AB2A 2WE5A 4JZ9A 3D40A 3LKKA 3QUOA 3QVHA
chains in the Genus database with same CATH topology
1GSJA 3C20A 2OGXA 3D2PA 3TVIA 4AXSA 4A7XA 2E9YA 3K4YA 2J0XA 2J4JA 4OLCA 2J5VA 3EK5A 2J4LA 2J4KA 4USJA 2IJ9A 2BMUA 2BNFA 2R98A 3EK6A 3LL5A 3D2MA 4F6TA 4I49A 1YBDA 1Z9DA 1B7BA 2X2WA 3AB4A 3K56A 2VA1A 3L76A 4NDOA 2BUFA 4AB7A 1OH9A 3D41A 4NDPA 1GS5A 3S6HA 4NDOB 4KZTA 2AP9A 3QUNA 1OHBA 2OGXB 2BTYA 4NDQA 2R8VA 2AKOA 3U6UA 2V5HA 2CDQA 3KZFA 3T7BA 4F6TB 4A7WA 2BRXA 3AAWA 2JI5A 3WWMA 2BRIA 3S6GA 2BNEA 3WWNA 1E19A 2W21A 2BNDA 4JZ8A 2J5TA 4JZ7A 3ZZGA 2HMFA 3QVFA 4NDPB 3C1MA 3LL9A 1OHAA 4Q1TA 3L86A 3S6KA 2J0WA 3B8GA 3K52A 4NDRA 2WE4A 2V4YA 2JJXA 3C1NA 2WXBA 4NDQB 2RD5A 2JJ4A 3ZZHA 3ZZFA 3ZZIA 2A1FA 4NDRB 3K4OA 3QURA 3NWYA 3AB2A 2WE5A 4JZ9A 3D40A 3LKKA 3QUOA 3QVHA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1GSJ A;  3C20 A;  2OGX A;  3D2P A;  3TVI A;  4AXS A;  4A7X A;  2E9Y A;  3K4Y A;  2J0X A;  2J4J A;  4OLC A;  2J5V A;  3EK5 A;  2J4L A;  2J4K A;  4USJ A;  2IJ9 A;  2BMU A;  2BNF A;  2R98 A;  3EK6 A;  3LL5 A;  3D2M A;  4F6T A;  4I49 A;  1YBD A;  1Z9D A;  1B7B A;  2X2W A;  3AB4 A;  3K56 A;  2VA1 A;  3L76 A;  4NDO A;  2BUF A;  4AB7 A;  1OH9 A;  3D41 A;  4NDP A;  1GS5 A;  3S6H A;  4NDO B;  4KZT A;  2AP9 A;  3QUN A;  1OHB A;  2OGX B;  2BTY A;  4NDQ A;  2R8V A;  2AKO A;  3U6U A;  2V5H A;  2CDQ A;  3KZF A;  3T7B A;  4F6T B;  4A7W A;  2BRX A;  3AAW A;  2JI5 A;  3WWM A;  2BRI A;  3S6G A;  2BNE A;  3WWN A;  1E19 A;  2W21 A;  2BND A;  4JZ8 A;  2J5T A;  4JZ7 A;  3ZZG A;  2HMF A;  3QVF A;  4NDP B;  3C1M A;  3LL9 A;  1OHA A;  4Q1T A;  3L86 A;  3S6K A;  2J0W A;  3B8G A;  3K52 A;  4NDR A;  2WE4 A;  2V4Y A;  2JJX A;  3C1N A;  2WXB A;  4NDQ B;  2RD5 A;  2JJ4 A;  3ZZH A;  3ZZF A;  3ZZI A;  2A1F A;  4NDR B;  3K4O A;  3QUR A;  3NWY A;  3AB2 A;  2WE5 A;  4JZ9 A;  3D40 A;  3LKK A;  3QUO A;  3QVH A; 
#chains in the Genus database with same CATH topology
 1GSJ A;  3C20 A;  2OGX A;  3D2P A;  3TVI A;  4AXS A;  4A7X A;  2E9Y A;  3K4Y A;  2J0X A;  2J4J A;  4OLC A;  2J5V A;  3EK5 A;  2J4L A;  2J4K A;  4USJ A;  2IJ9 A;  2BMU A;  2BNF A;  2R98 A;  3EK6 A;  3LL5 A;  3D2M A;  4F6T A;  4I49 A;  1YBD A;  1Z9D A;  1B7B A;  2X2W A;  3AB4 A;  3K56 A;  2VA1 A;  3L76 A;  4NDO A;  2BUF A;  4AB7 A;  1OH9 A;  3D41 A;  4NDP A;  1GS5 A;  3S6H A;  4NDO B;  4KZT A;  2AP9 A;  3QUN A;  1OHB A;  2OGX B;  2BTY A;  4NDQ A;  2R8V A;  2AKO A;  3U6U A;  2V5H A;  2CDQ A;  3KZF A;  3T7B A;  4F6T B;  4A7W A;  2BRX A;  3AAW A;  2JI5 A;  3WWM A;  2BRI A;  3S6G A;  2BNE A;  3WWN A;  1E19 A;  2W21 A;  2BND A;  4JZ8 A;  2J5T A;  4JZ7 A;  3ZZG A;  2HMF A;  3QVF A;  4NDP B;  3C1M A;  3LL9 A;  1OHA A;  4Q1T A;  3L86 A;  3S6K A;  2J0W A;  3B8G A;  3K52 A;  4NDR A;  2WE4 A;  2V4Y A;  2JJX A;  3C1N A;  2WXB A;  4NDQ B;  2RD5 A;  2JJ4 A;  3ZZH A;  3ZZF A;  3ZZI A;  2A1F A;  4NDR B;  3K4O A;  3QUR A;  3NWY A;  3AB2 A;  2WE5 A;  4JZ9 A;  3D40 A;  3LKK A;  3QUO A;  3QVH A; 
#chains in the Genus database with same CATH homology
 1GSJ A;  3C20 A;  2OGX A;  3D2P A;  3TVI A;  4AXS A;  4A7X A;  2E9Y A;  3K4Y A;  2J0X A;  2J4J A;  4OLC A;  2J5V A;  3EK5 A;  2J4L A;  2J4K A;  4USJ A;  2IJ9 A;  2BMU A;  2BNF A;  2R98 A;  3EK6 A;  3LL5 A;  3D2M A;  4F6T A;  4I49 A;  1YBD A;  1Z9D A;  1B7B A;  2X2W A;  3AB4 A;  3K56 A;  2VA1 A;  3L76 A;  4NDO A;  2BUF A;  4AB7 A;  1OH9 A;  3D41 A;  4NDP A;  1GS5 A;  3S6H A;  4NDO B;  4KZT A;  2AP9 A;  3QUN A;  1OHB A;  2OGX B;  2BTY A;  4NDQ A;  2R8V A;  2AKO A;  3U6U A;  2V5H A;  2CDQ A;  3KZF A;  3T7B A;  4F6T B;  4A7W A;  2BRX A;  3AAW A;  2JI5 A;  3WWM A;  2BRI A;  3S6G A;  2BNE A;  3WWN A;  1E19 A;  2W21 A;  2BND A;  4JZ8 A;  2J5T A;  4JZ7 A;  3ZZG A;  2HMF A;  3QVF A;  4NDP B;  3C1M A;  3LL9 A;  1OHA A;  4Q1T A;  3L86 A;  3S6K A;  2J0W A;  3B8G A;  3K52 A;  4NDR A;  2WE4 A;  2V4Y A;  2JJX A;  3C1N A;  2WXB A;  4NDQ B;  2RD5 A;  2JJ4 A;  3ZZH A;  3ZZF A;  3ZZI A;  2A1F A;  4NDR B;  3K4O A;  3QUR A;  3NWY A;  3AB2 A;  2WE5 A;  4JZ9 A;  3D40 A;  3LKK A;  3QUO A;  3QVH A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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