4OLCA

Carbamate kinase from giardia lamblia thiocarbamoylated by disulfiram on cys242
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
315
structure length
308
Chain Sequence
SAGKTVVIALGGNAMLQAKEKGDYDTQRKNVEIAASEIYKIHKAGYKVVLTSGNGPQVGAIKLQNQAAAGVSPEMPLHVCGAMSQGFIGYMMSQAMDNVFCANNEPANCVTCVTQTLVDPKDQAFTNPTKPVGRFYTEQEAKDLMAANPGKILREDAGRGWRVVVPSPRPLEIVEYGVIKTLIDNNVLVICTNGGGIPCKRENKVISGVDAVIDKDLATSLLAKTLNSDYLMILTDVLNACIRKLEEIKLSEILALEKDGHFAAGSMGPKVRAAIEFTQATGKMSIITSLSTAVDALNGKCGTRIIKD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
pubmed doi rcsb
molecule tags Transferase
source organism Giardia lamblia
molecule keywords Carbamate kinase
total genus 100
structure length 308
sequence length 315
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.2: Carbamate kinase.
pdb deposition date 2014-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 4olcA00
3ZZHA 2CDQA 1Z9DA 2OGXB 3WWNA 3LKKA 4USJA 4NDOB 2J5TA 2JJ4A 3QVFA 3L86A 3K4OA 1OH9A 2OGXA 2BRIA 2J5VA 1YBDA 2BNEA 3K52A 4JZ9A 4NDOA 2BMUA 4F6TB 3KZFA 3ZZGA 4JZ8A 2J4KA 2WXBA 2E9YA 3TVIA 3QURA 4NDPB 4F6TA 3S6GA 2AKOA 4A7WA 4A7XA 3ZZFA 4I49A 2JI5A 3D2MA 2V5HA 3T7BA 4NDPA 3AAWA 3QUOA 3WWMA 2RD5A 2R8VA 3EK5A 2VA1A 2BNFA 2J0WA 4OLCA 3D41A 3C1MA 1GS5A 2V4YA 1E19A 3NWYA 3QVHA 3U6UA 3ZZIA 4NDQB 3L76A 4NDRB 3AB4A 3QUNA 4AXSA 1B7BA 2R98A 2BNDA 3LL9A 2BTYA 2JJXA 3B8GA 2WE5A 4NDQA 1GSJA 4NDRA 2HMFA 2J4LA 1OHBA 4JZ7A 2AP9A 3K56A 4AB7A 4KZTA 2A1FA 3S6KA 3EK6A 2BUFA 2J0XA 2WE4A 3C1NA 1OHAA 2X2WA 2J4JA 3D2PA 3K4YA 2BRXA 3C20A 3LL5A 2W21A 2IJ9A 3D40A 3S6HA 4Q1TA 3AB2A
chains in the Genus database with same CATH superfamily
3ZZHA 2CDQA 1Z9DA 2OGXB 3WWNA 3LKKA 4USJA 4NDOB 2J5TA 2JJ4A 3QVFA 3L86A 3K4OA 1OH9A 2OGXA 2BRIA 2J5VA 1YBDA 2BNEA 3K52A 4JZ9A 4NDOA 2BMUA 4F6TB 3KZFA 3ZZGA 4JZ8A 2J4KA 2WXBA 2E9YA 3TVIA 3QURA 4NDPB 4F6TA 3S6GA 2AKOA 4A7WA 4A7XA 3ZZFA 4I49A 2JI5A 3D2MA 2V5HA 3T7BA 4NDPA 3AAWA 3QUOA 3WWMA 2RD5A 2R8VA 3EK5A 2VA1A 2BNFA 2J0WA 4OLCA 3D41A 3C1MA 1GS5A 2V4YA 1E19A 3NWYA 3QVHA 3U6UA 3ZZIA 4NDQB 3L76A 4NDRB 3AB4A 3QUNA 4AXSA 1B7BA 2R98A 2BNDA 3LL9A 2BTYA 2JJXA 3B8GA 2WE5A 4NDQA 1GSJA 4NDRA 2HMFA 2J4LA 1OHBA 4JZ7A 2AP9A 3K56A 4AB7A 4KZTA 2A1FA 3S6KA 3EK6A 2BUFA 2J0XA 2WE4A 3C1NA 1OHAA 2X2WA 2J4JA 3D2PA 3K4YA 2BRXA 3C20A 3LL5A 2W21A 2IJ9A 3D40A 3S6HA 4Q1TA 3AB2A
chains in the Genus database with same CATH topology
3ZZHA 2CDQA 1Z9DA 2OGXB 3WWNA 3LKKA 4USJA 4NDOB 2J5TA 2JJ4A 3QVFA 3L86A 3K4OA 1OH9A 2OGXA 2BRIA 2J5VA 1YBDA 2BNEA 3K52A 4JZ9A 4NDOA 2BMUA 4F6TB 3KZFA 3ZZGA 4JZ8A 2J4KA 2WXBA 2E9YA 3TVIA 3QURA 4NDPB 4F6TA 3S6GA 2AKOA 4A7WA 4A7XA 3ZZFA 4I49A 2JI5A 3D2MA 2V5HA 3T7BA 4NDPA 3AAWA 3QUOA 3WWMA 2RD5A 2R8VA 3EK5A 2VA1A 2BNFA 2J0WA 4OLCA 3D41A 3C1MA 1GS5A 2V4YA 1E19A 3NWYA 3QVHA 3U6UA 3ZZIA 4NDQB 3L76A 4NDRB 3AB4A 3QUNA 4AXSA 1B7BA 2R98A 2BNDA 3LL9A 2BTYA 2JJXA 3B8GA 2WE5A 4NDQA 1GSJA 4NDRA 2HMFA 2J4LA 1OHBA 4JZ7A 2AP9A 3K56A 4AB7A 4KZTA 2A1FA 3S6KA 3EK6A 2BUFA 2J0XA 2WE4A 3C1NA 1OHAA 2X2WA 2J4JA 3D2PA 3K4YA 2BRXA 3C20A 3LL5A 2W21A 2IJ9A 3D40A 3S6HA 4Q1TA 3AB2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZZH A;  2CDQ A;  1Z9D A;  2OGX B;  3WWN A;  3LKK A;  4USJ A;  4NDO B;  2J5T A;  2JJ4 A;  3QVF A;  3L86 A;  3K4O A;  1OH9 A;  2OGX A;  2BRI A;  2J5V A;  1YBD A;  2BNE A;  3K52 A;  4JZ9 A;  4NDO A;  2BMU A;  4F6T B;  3KZF A;  3ZZG A;  4JZ8 A;  2J4K A;  2WXB A;  2E9Y A;  3TVI A;  3QUR A;  4NDP B;  4F6T A;  3S6G A;  2AKO A;  4A7W A;  4A7X A;  3ZZF A;  4I49 A;  2JI5 A;  3D2M A;  2V5H A;  3T7B A;  4NDP A;  3AAW A;  3QUO A;  3WWM A;  2RD5 A;  2R8V A;  3EK5 A;  2VA1 A;  2BNF A;  2J0W A;  4OLC A;  3D41 A;  3C1M A;  1GS5 A;  2V4Y A;  1E19 A;  3NWY A;  3QVH A;  3U6U A;  3ZZI A;  4NDQ B;  3L76 A;  4NDR B;  3AB4 A;  3QUN A;  4AXS A;  1B7B A;  2R98 A;  2BND A;  3LL9 A;  2BTY A;  2JJX A;  3B8G A;  2WE5 A;  4NDQ A;  1GSJ A;  4NDR A;  2HMF A;  2J4L A;  1OHB A;  4JZ7 A;  2AP9 A;  3K56 A;  4AB7 A;  4KZT A;  2A1F A;  3S6K A;  3EK6 A;  2BUF A;  2J0X A;  2WE4 A;  3C1N A;  1OHA A;  2X2W A;  2J4J A;  3D2P A;  3K4Y A;  2BRX A;  3C20 A;  3LL5 A;  2W21 A;  2IJ9 A;  3D40 A;  3S6H A;  4Q1T A;  3AB2 A; 
#chains in the Genus database with same CATH topology
 3ZZH A;  2CDQ A;  1Z9D A;  2OGX B;  3WWN A;  3LKK A;  4USJ A;  4NDO B;  2J5T A;  2JJ4 A;  3QVF A;  3L86 A;  3K4O A;  1OH9 A;  2OGX A;  2BRI A;  2J5V A;  1YBD A;  2BNE A;  3K52 A;  4JZ9 A;  4NDO A;  2BMU A;  4F6T B;  3KZF A;  3ZZG A;  4JZ8 A;  2J4K A;  2WXB A;  2E9Y A;  3TVI A;  3QUR A;  4NDP B;  4F6T A;  3S6G A;  2AKO A;  4A7W A;  4A7X A;  3ZZF A;  4I49 A;  2JI5 A;  3D2M A;  2V5H A;  3T7B A;  4NDP A;  3AAW A;  3QUO A;  3WWM A;  2RD5 A;  2R8V A;  3EK5 A;  2VA1 A;  2BNF A;  2J0W A;  4OLC A;  3D41 A;  3C1M A;  1GS5 A;  2V4Y A;  1E19 A;  3NWY A;  3QVH A;  3U6U A;  3ZZI A;  4NDQ B;  3L76 A;  4NDR B;  3AB4 A;  3QUN A;  4AXS A;  1B7B A;  2R98 A;  2BND A;  3LL9 A;  2BTY A;  2JJX A;  3B8G A;  2WE5 A;  4NDQ A;  1GSJ A;  4NDR A;  2HMF A;  2J4L A;  1OHB A;  4JZ7 A;  2AP9 A;  3K56 A;  4AB7 A;  4KZT A;  2A1F A;  3S6K A;  3EK6 A;  2BUF A;  2J0X A;  2WE4 A;  3C1N A;  1OHA A;  2X2W A;  2J4J A;  3D2P A;  3K4Y A;  2BRX A;  3C20 A;  3LL5 A;  2W21 A;  2IJ9 A;  3D40 A;  3S6H A;  4Q1T A;  3AB2 A; 
#chains in the Genus database with same CATH homology
 3ZZH A;  2CDQ A;  1Z9D A;  2OGX B;  3WWN A;  3LKK A;  4USJ A;  4NDO B;  2J5T A;  2JJ4 A;  3QVF A;  3L86 A;  3K4O A;  1OH9 A;  2OGX A;  2BRI A;  2J5V A;  1YBD A;  2BNE A;  3K52 A;  4JZ9 A;  4NDO A;  2BMU A;  4F6T B;  3KZF A;  3ZZG A;  4JZ8 A;  2J4K A;  2WXB A;  2E9Y A;  3TVI A;  3QUR A;  4NDP B;  4F6T A;  3S6G A;  2AKO A;  4A7W A;  4A7X A;  3ZZF A;  4I49 A;  2JI5 A;  3D2M A;  2V5H A;  3T7B A;  4NDP A;  3AAW A;  3QUO A;  3WWM A;  2RD5 A;  2R8V A;  3EK5 A;  2VA1 A;  2BNF A;  2J0W A;  4OLC A;  3D41 A;  3C1M A;  1GS5 A;  2V4Y A;  1E19 A;  3NWY A;  3QVH A;  3U6U A;  3ZZI A;  4NDQ B;  3L76 A;  4NDR B;  3AB4 A;  3QUN A;  4AXS A;  1B7B A;  2R98 A;  2BND A;  3LL9 A;  2BTY A;  2JJX A;  3B8G A;  2WE5 A;  4NDQ A;  1GSJ A;  4NDR A;  2HMF A;  2J4L A;  1OHB A;  4JZ7 A;  2AP9 A;  3K56 A;  4AB7 A;  4KZT A;  2A1F A;  3S6K A;  3EK6 A;  2BUF A;  2J0X A;  2WE4 A;  3C1N A;  1OHA A;  2X2W A;  2J4J A;  3D2P A;  3K4Y A;  2BRX A;  3C20 A;  3LL5 A;  2W21 A;  2IJ9 A;  3D40 A;  3S6H A;  4Q1T A;  3AB2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...