1VE2A

Crystal structure of uroporphyrin-iii-c-methyltransferase from thermus thermophilus
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
235
structure length
222
Chain Sequence
MRGKVYLVGAGFGGPEHLTLKALRVLEVAEVVLHDRLVHPGVLALAKGELVPVKTPQEAITARLIALAREGRVVARLKGGDPMVFGRGGEEALALRRAGIPFEVVPGVTSAVGALSALGLPLTHRGLARSFAVATGHDPALPLPRADTLVLLMGLKERLLERFPPETPLALLARVGWPGEAVRLGRVEDLPGLGEGLPSPALLVVGKVVGLYGELLPKDHGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Uroporphyrin-III-C-Methyltrans from Thermus Thermophilus
rcsb
molecule tags Transferase
source organism Thermus thermophilus
molecule keywords Uroporphyrin-III C-methyltransferase
total genus 59
structure length 222
sequence length 235
chains with identical sequence B
ec nomenclature ec 2.1.1.107: Uroporphyrinogen-III C-methyltransferase.
pdb deposition date 2004-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 1ve2A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 1ve2A01
5HW4A 2DXWA 2ED5A 2EL1A 2PCKA 2EMUA 2E0KA 2P9DA 2OWVA 2E8HA 2P5FA 2Z6RA 2P6KA 3HH1A 2EK7A 2E8SA 2OWGA 1PJQA 2OWKA 2E4NA 2DEKA 2P5CA 2PCIA 2HUVA 2E16A 2EGSA 3FQ6A 2DV3A 2OWUA 2DSGA 2DV4A 2E17A 2EKAA 2EK3A 2EH4A 2DV7A 3ND1A 2YBOA 2YBQA 3NUTA 2EK2A 2EL3A 4E16A 2P6IA 2P6LA 1WNGA 2DSHA 2NPNA 3FFYA 2BB3A 2EJKA 3NEIA 2ED3A 3KWPA 1VE2A 1WYZA 2E0NA 1V9AA 2E7RA 2EJZA 2HUTA 2E07A 2EEQA 2DSIA 2HUXA 2EN5A 2PB5A 2PB4A 2QBUA 2CBFA 1PJSA 2E8RA 2ZVBA 2EJJA 2EMRA 1PJTA 1CBFA 2PCHA 2EGBA 2EL0A 2P2XA 3NDCA 2PB6A 2EGLA 1VCEA 2EK4A 2PCGA 2E8QA 2EH2A 2ELDA 2PCAA 1WDEA 2DXXA 1VHVA 2E15A 1S4DA 2ENIA 2EH5A 2P6DA 2ELEA 3I4TA 2OWFA 2E4RA 2HUQA 2DXVA 2ZVCA 2DV5A 2HR8A 1VA0A 2EHCA 2PCMA 2EL2A 2E08A 2EHLA
chains in the Genus database with same CATH superfamily
5HW4A 3SZLA 2DXWA 2ED5A 4MV5A 3KE9A 3UV7A 3F7TA 2KYYA 2EL1A 2PCKA 3KE8A 2EMUA 2E0KA 2P9DA 3KEMA 3UTDA 2OWVA 3T0FA 2E8HA 2P5FA 2Z6RA 2P6KA 3UTCA 3HH1A 3ZGLA 2EK7A 3SZOA 3UWMA 2E8SA 2OWGA 3URKA 1PJQA 2OWKA 2E4NA 2DEKA 2P5CA 2PCIA 2HUVA 2E16A 2EGSA 3FQ6A 3DNFA 2DV3A 3TIXB 2OWUA 2DSGA 2DV4A 2E17A 2EKAA 4EB3A 4MUYA 2EK3A 2EH4A 3SZUA 2DV7A 3ND1A 4H4CA 2YBOA 2YBQA 3NUTA 2EK2A 2EL3A 4E16A 2P6IA 2P6LA 1WNGA 2DSHA 3T0GA 2NPNA 3FFYA 2BB3A 2EJKA 3NEIA 2ED3A 3KWPA 3KELA 1VE2A 4H4EA 1WYZA 2E0NA 1V9AA 2E7RA 2EJZA 2HUTA 2E07A 2EEQA 3ZGNA 2DSIA 2HUXA 4H4DA 2EN5A 2PB5A 2PB4A 2QBUA 2CBFA 1PJSA 2E8RA 2ZVBA 2EJJA 2EMRA 4MV0A 1PJTA 1CBFA 2PCHA 2EGBA 2EL0A 2P2XA 3NDCA 3KEFA 2PB6A 2EGLA 1VCEA 2EK4A 2PCGA 3LMMA 3UV6A 2E8QA 2EH2A 2ELDA 2PCAA 4MUXA 1WDEA 2DXXA 1VHVA 2E15A 1S4DA 2ENIA 2EH5A 2P6DA 2ELEA 3UV3A 3I4TA 2OWFA 2E4RA 2HUQA 2DXVA 2ZVCA 2DV5A 2HR8A 1VA0A 2EHCA 4N7BA 2PCMA 2EL2A 2E08A 2EHLA
chains in the Genus database with same CATH topology
5HW4A 3SZLA 2DXWA 2ED5A 4MV5A 3KE9A 3UV7A 3F7TA 2KYYA 2EL1A 2PCKA 3KE8A 2EMUA 2E0KA 2P9DA 3KEMA 3UTDA 2OWVA 3T0FA 2E8HA 2P5FA 2Z6RA 2P6KA 3UTCA 3HH1A 3ZGLA 2EK7A 3SZOA 3UWMA 2E8SA 2OWGA 3URKA 1PJQA 2OWKA 2E4NA 2DEKA 2P5CA 2PCIA 2HUVA 2E16A 2EGSA 3FQ6A 3DNFA 2DV3A 3TIXB 2OWUA 2DSGA 2DV4A 2E17A 2EKAA 4EB3A 4MUYA 2EK3A 2EH4A 3SZUA 2DV7A 3ND1A 4H4CA 2YBOA 2YBQA 3NUTA 2EK2A 2EL3A 4E16A 2P6IA 2P6LA 1WNGA 2DSHA 3T0GA 2NPNA 3FFYA 2BB3A 2EJKA 3NEIA 2ED3A 3KWPA 3KELA 1VE2A 4H4EA 1WYZA 2E0NA 1V9AA 2E7RA 2EJZA 2HUTA 2E07A 2EEQA 3ZGNA 2DSIA 2HUXA 4H4DA 2EN5A 2PB5A 2PB4A 2QBUA 2CBFA 1PJSA 2E8RA 2ZVBA 2EJJA 2EMRA 4MV0A 1PJTA 1CBFA 2PCHA 2EGBA 2EL0A 2P2XA 3NDCA 3KEFA 2PB6A 2EGLA 1VCEA 2EK4A 2PCGA 3LMMA 3UV6A 2E8QA 2EH2A 2ELDA 2PCAA 4MUXA 1WDEA 2DXXA 1VHVA 2E15A 1S4DA 2ENIA 2EH5A 2P6DA 2ELEA 3UV3A 3I4TA 2OWFA 2E4RA 2HUQA 2DXVA 2ZVCA 2DV5A 2HR8A 1VA0A 2EHCA 4N7BA 2PCMA 2EL2A 2E08A 2EHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HW4 A;  2DXW A;  2ED5 A;  2EL1 A;  2PCK A;  2EMU A;  2E0K A;  2P9D A;  2OWV A;  2E8H A;  2P5F A;  2Z6R A;  2P6K A;  3HH1 A;  2EK7 A;  2E8S A;  2OWG A;  1PJQ A;  2OWK A;  2E4N A;  2DEK A;  2P5C A;  2PCI A;  2HUV A;  2E16 A;  2EGS A;  3FQ6 A;  2DV3 A;  2OWU A;  2DSG A;  2DV4 A;  2E17 A;  2EKA A;  2EK3 A;  2EH4 A;  2DV7 A;  3ND1 A;  2YBO A;  2YBQ A;  3NUT A;  2EK2 A;  2EL3 A;  4E16 A;  2P6I A;  2P6L A;  1WNG A;  2DSH A;  2NPN A;  3FFY A;  2BB3 A;  2EJK A;  3NEI A;  2ED3 A;  3KWP A;  1VE2 A;  1WYZ A;  2E0N A;  1V9A A;  2E7R A;  2EJZ A;  2HUT A;  2E07 A;  2EEQ A;  2DSI A;  2HUX A;  2EN5 A;  2PB5 A;  2PB4 A;  2QBU A;  2CBF A;  1PJS A;  2E8R A;  2ZVB A;  2EJJ A;  2EMR A;  1PJT A;  1CBF A;  2PCH A;  2EGB A;  2EL0 A;  2P2X A;  3NDC A;  2PB6 A;  2EGL A;  1VCE A;  2EK4 A;  2PCG A;  2E8Q A;  2EH2 A;  2ELD A;  2PCA A;  1WDE A;  2DXX A;  1VHV A;  2E15 A;  1S4D A;  2ENI A;  2EH5 A;  2P6D A;  2ELE A;  3I4T A;  2OWF A;  2E4R A;  2HUQ A;  2DXV A;  2ZVC A;  2DV5 A;  2HR8 A;  1VA0 A;  2EHC A;  2PCM A;  2EL2 A;  2E08 A;  2EHL A; 
#chains in the Genus database with same CATH topology
 5HW4 A;  3SZL A;  2DXW A;  2ED5 A;  4MV5 A;  3KE9 A;  3UV7 A;  3F7T A;  2KYY A;  2EL1 A;  2PCK A;  3KE8 A;  2EMU A;  2E0K A;  2P9D A;  3KEM A;  3UTD A;  2OWV A;  3T0F A;  2E8H A;  2P5F A;  2Z6R A;  2P6K A;  3UTC A;  3HH1 A;  3ZGL A;  2EK7 A;  3SZO A;  3UWM A;  2E8S A;  2OWG A;  3URK A;  1PJQ A;  2OWK A;  2E4N A;  2DEK A;  2P5C A;  2PCI A;  2HUV A;  2E16 A;  2EGS A;  3FQ6 A;  3DNF A;  2DV3 A;  3TIX B;  2OWU A;  2DSG A;  2DV4 A;  2E17 A;  2EKA A;  4EB3 A;  4MUY A;  2EK3 A;  2EH4 A;  3SZU A;  2DV7 A;  3ND1 A;  4H4C A;  2YBO A;  2YBQ A;  3NUT A;  2EK2 A;  2EL3 A;  4E16 A;  2P6I A;  2P6L A;  1WNG A;  2DSH A;  3T0G A;  2NPN A;  3FFY A;  2BB3 A;  2EJK A;  3NEI A;  2ED3 A;  3KWP A;  3KEL A;  1VE2 A;  4H4E A;  1WYZ A;  2E0N A;  1V9A A;  2E7R A;  2EJZ A;  2HUT A;  2E07 A;  2EEQ A;  3ZGN A;  2DSI A;  2HUX A;  4H4D A;  2EN5 A;  2PB5 A;  2PB4 A;  2QBU A;  2CBF A;  1PJS A;  2E8R A;  2ZVB A;  2EJJ A;  2EMR A;  4MV0 A;  1PJT A;  1CBF A;  2PCH A;  2EGB A;  2EL0 A;  2P2X A;  3NDC A;  3KEF A;  2PB6 A;  2EGL A;  1VCE A;  2EK4 A;  2PCG A;  3LMM A;  3UV6 A;  2E8Q A;  2EH2 A;  2ELD A;  2PCA A;  4MUX A;  1WDE A;  2DXX A;  1VHV A;  2E15 A;  1S4D A;  2ENI A;  2EH5 A;  2P6D A;  2ELE A;  3UV3 A;  3I4T A;  2OWF A;  2E4R A;  2HUQ A;  2DXV A;  2ZVC A;  2DV5 A;  2HR8 A;  1VA0 A;  2EHC A;  4N7B A;  2PCM A;  2EL2 A;  2E08 A;  2EHL A; 
#chains in the Genus database with same CATH homology
 5HW4 A;  3SZL A;  2DXW A;  2ED5 A;  4MV5 A;  3KE9 A;  3UV7 A;  3F7T A;  2KYY A;  2EL1 A;  2PCK A;  3KE8 A;  2EMU A;  2E0K A;  2P9D A;  3KEM A;  3UTD A;  2OWV A;  3T0F A;  2E8H A;  2P5F A;  2Z6R A;  2P6K A;  3UTC A;  3HH1 A;  3ZGL A;  2EK7 A;  3SZO A;  3UWM A;  2E8S A;  2OWG A;  3URK A;  1PJQ A;  2OWK A;  2E4N A;  2DEK A;  2P5C A;  2PCI A;  2HUV A;  2E16 A;  2EGS A;  3FQ6 A;  3DNF A;  2DV3 A;  3TIX B;  2OWU A;  2DSG A;  2DV4 A;  2E17 A;  2EKA A;  4EB3 A;  4MUY A;  2EK3 A;  2EH4 A;  3SZU A;  2DV7 A;  3ND1 A;  4H4C A;  2YBO A;  2YBQ A;  3NUT A;  2EK2 A;  2EL3 A;  4E16 A;  2P6I A;  2P6L A;  1WNG A;  2DSH A;  3T0G A;  2NPN A;  3FFY A;  2BB3 A;  2EJK A;  3NEI A;  2ED3 A;  3KWP A;  3KEL A;  1VE2 A;  4H4E A;  1WYZ A;  2E0N A;  1V9A A;  2E7R A;  2EJZ A;  2HUT A;  2E07 A;  2EEQ A;  3ZGN A;  2DSI A;  2HUX A;  4H4D A;  2EN5 A;  2PB5 A;  2PB4 A;  2QBU A;  2CBF A;  1PJS A;  2E8R A;  2ZVB A;  2EJJ A;  2EMR A;  4MV0 A;  1PJT A;  1CBF A;  2PCH A;  2EGB A;  2EL0 A;  2P2X A;  3NDC A;  3KEF A;  2PB6 A;  2EGL A;  1VCE A;  2EK4 A;  2PCG A;  3LMM A;  3UV6 A;  2E8Q A;  2EH2 A;  2ELD A;  2PCA A;  4MUX A;  1WDE A;  2DXX A;  1VHV A;  2E15 A;  1S4D A;  2ENI A;  2EH5 A;  2P6D A;  2ELE A;  3UV3 A;  3I4T A;  2OWF A;  2E4R A;  2HUQ A;  2DXV A;  2ZVC A;  2DV5 A;  2HR8 A;  1VA0 A;  2EHC A;  4N7B A;  2PCM A;  2EL2 A;  2E08 A;  2EHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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