2E15A

Crystal structure of arg173 to asn mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKNMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e15A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e15A01
2E8QA 2EMUA 2EMRA 2HUVA 2DXXA 2OWFA 2DV5A 2YBOA 1PJSA 4E16A 2PB6A 2E7RA 3FFYA 2EL1A 3FQ6A 2P5FA 1WDEA 1VE2A 2EJZA 2DXWA 2E4RA 2ENIA 2EL3A 2HR8A 2EKAA 2CBFA 2DSIA 2PCKA 2PCAA 2ELDA 2PCIA 2P6LA 2NPNA 2ED3A 2HUQA 2OWKA 2E4NA 2DEKA 2DV3A 2HUXA 2P9DA 2EL0A 3NDCA 3KWPA 3I4TA 2PB5A 2DV4A 1VCEA 2QBUA 1CBFA 2E08A 2DXVA 2ED5A 1WYZA 2E8HA 2EGSA 5HW4A 2EH2A 2DV7A 2ELEA 2EJKA 2EHCA 2Z6RA 1VHVA 2E15A 3NUTA 1V9AA 2ZVCA 2BB3A 2OWUA 2EHLA 2P2XA 2EGLA 2DSHA 2E16A 2HUTA 2EJJA 2P6IA 2PCGA 1PJQA 2EN5A 2E0KA 2E17A 3NEIA 2PB4A 2EK3A 2EH5A 2PCHA 2EK7A 2E8SA 2EEQA 2EGBA 2P6DA 1VA0A 2P6KA 2P5CA 2EK2A 2EK4A 2E07A 2E8RA 1PJTA 2EL2A 2PCMA 2ZVBA 2OWGA 2EH4A 2OWVA 2DSGA 1WNGA 2YBQA 2E0NA 1S4DA 3ND1A 3HH1A
chains in the Genus database with same CATH superfamily
3T0GA 4MUYA 2E8QA 2EMUA 2EMRA 2HUVA 2DXXA 2OWFA 2DV5A 2YBOA 1PJSA 4E16A 2PB6A 3UWMA 2E7RA 3FFYA 2EL1A 3FQ6A 2P5FA 1WDEA 1VE2A 2EJZA 3TIXB 2DXWA 2E4RA 3UV3A 2ENIA 3ZGLA 2EL3A 2HR8A 2EKAA 2CBFA 2DSIA 2PCKA 2PCAA 2ELDA 2PCIA 3KE8A 2P6LA 4MV5A 2NPNA 2ED3A 3T0FA 2HUQA 2OWKA 2E4NA 2DEKA 2DV3A 2HUXA 2P9DA 3ZGNA 2EL0A 3NDCA 3KWPA 3I4TA 2PB5A 2DV4A 1VCEA 2QBUA 1CBFA 2E08A 2DXVA 2ED5A 4MV0A 3UV7A 4N7BA 3DNFA 1WYZA 2E8HA 2EGSA 5HW4A 2EH2A 2DV7A 3F7TA 2ELEA 2EJKA 2EHCA 2Z6RA 1VHVA 2E15A 3NUTA 1V9AA 2ZVCA 3SZLA 2BB3A 2OWUA 4H4CA 2EHLA 3SZOA 3LMMA 2P2XA 3KE9A 2EGLA 2DSHA 2E16A 4H4EA 3SZUA 3UV6A 2HUTA 2EJJA 2P6IA 3KEFA 2PCGA 1PJQA 2EN5A 2E0KA 2E17A 3NEIA 2KYYA 2PB4A 2EK3A 4H4DA 2EH5A 2PCHA 2EK7A 2E8SA 2EEQA 2EGBA 2P6DA 1VA0A 2P6KA 2P5CA 2EK2A 4MUXA 4EB3A 2EK4A 2E07A 2E8RA 1PJTA 2EL2A 2PCMA 2ZVBA 3KEMA 2OWGA 3UTCA 3KELA 3UTDA 2EH4A 2OWVA 2DSGA 1WNGA 2YBQA 2E0NA 3URKA 1S4DA 3ND1A 3HH1A
chains in the Genus database with same CATH topology
3T0GA 4MUYA 2E8QA 2EMUA 2EMRA 2HUVA 2DXXA 2OWFA 2DV5A 2YBOA 1PJSA 4E16A 2PB6A 3UWMA 2E7RA 3FFYA 2EL1A 3FQ6A 2P5FA 1WDEA 1VE2A 2EJZA 3TIXB 2DXWA 2E4RA 3UV3A 2ENIA 3ZGLA 2EL3A 2HR8A 2EKAA 2CBFA 2DSIA 2PCKA 2PCAA 2ELDA 2PCIA 3KE8A 2P6LA 4MV5A 2NPNA 2ED3A 3T0FA 2HUQA 2OWKA 2E4NA 2DEKA 2DV3A 2HUXA 2P9DA 3ZGNA 2EL0A 3NDCA 3KWPA 3I4TA 2PB5A 2DV4A 1VCEA 2QBUA 1CBFA 2E08A 2DXVA 2ED5A 4MV0A 3UV7A 4N7BA 3DNFA 1WYZA 2E8HA 2EGSA 5HW4A 2EH2A 2DV7A 3F7TA 2ELEA 2EJKA 2EHCA 2Z6RA 1VHVA 2E15A 3NUTA 1V9AA 2ZVCA 3SZLA 2BB3A 2OWUA 4H4CA 2EHLA 3SZOA 3LMMA 2P2XA 3KE9A 2EGLA 2DSHA 2E16A 4H4EA 3SZUA 3UV6A 2HUTA 2EJJA 2P6IA 3KEFA 2PCGA 1PJQA 2EN5A 2E0KA 2E17A 3NEIA 2KYYA 2PB4A 2EK3A 4H4DA 2EH5A 2PCHA 2EK7A 2E8SA 2EEQA 2EGBA 2P6DA 1VA0A 2P6KA 2P5CA 2EK2A 4MUXA 4EB3A 2EK4A 2E07A 2E8RA 1PJTA 2EL2A 2PCMA 2ZVBA 3KEMA 2OWGA 3UTCA 3KELA 3UTDA 2EH4A 2OWVA 2DSGA 1WNGA 2YBQA 2E0NA 3URKA 1S4DA 3ND1A 3HH1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E8Q A;  2EMU A;  2EMR A;  2HUV A;  2DXX A;  2OWF A;  2DV5 A;  2YBO A;  1PJS A;  4E16 A;  2PB6 A;  2E7R A;  3FFY A;  2EL1 A;  3FQ6 A;  2P5F A;  1WDE A;  1VE2 A;  2EJZ A;  2DXW A;  2E4R A;  2ENI A;  2EL3 A;  2HR8 A;  2EKA A;  2CBF A;  2DSI A;  2PCK A;  2PCA A;  2ELD A;  2PCI A;  2P6L A;  2NPN A;  2ED3 A;  2HUQ A;  2OWK A;  2E4N A;  2DEK A;  2DV3 A;  2HUX A;  2P9D A;  2EL0 A;  3NDC A;  3KWP A;  3I4T A;  2PB5 A;  2DV4 A;  1VCE A;  2QBU A;  1CBF A;  2E08 A;  2DXV A;  2ED5 A;  1WYZ A;  2E8H A;  2EGS A;  5HW4 A;  2EH2 A;  2DV7 A;  2ELE A;  2EJK A;  2EHC A;  2Z6R A;  1VHV A;  2E15 A;  3NUT A;  1V9A A;  2ZVC A;  2BB3 A;  2OWU A;  2EHL A;  2P2X A;  2EGL A;  2DSH A;  2E16 A;  2HUT A;  2EJJ A;  2P6I A;  2PCG A;  1PJQ A;  2EN5 A;  2E0K A;  2E17 A;  3NEI A;  2PB4 A;  2EK3 A;  2EH5 A;  2PCH A;  2EK7 A;  2E8S A;  2EEQ A;  2EGB A;  2P6D A;  1VA0 A;  2P6K A;  2P5C A;  2EK2 A;  2EK4 A;  2E07 A;  2E8R A;  1PJT A;  2EL2 A;  2PCM A;  2ZVB A;  2OWG A;  2EH4 A;  2OWV A;  2DSG A;  1WNG A;  2YBQ A;  2E0N A;  1S4D A;  3ND1 A;  3HH1 A; 
#chains in the Genus database with same CATH topology
 3T0G A;  4MUY A;  2E8Q A;  2EMU A;  2EMR A;  2HUV A;  2DXX A;  2OWF A;  2DV5 A;  2YBO A;  1PJS A;  4E16 A;  2PB6 A;  3UWM A;  2E7R A;  3FFY A;  2EL1 A;  3FQ6 A;  2P5F A;  1WDE A;  1VE2 A;  2EJZ A;  3TIX B;  2DXW A;  2E4R A;  3UV3 A;  2ENI A;  3ZGL A;  2EL3 A;  2HR8 A;  2EKA A;  2CBF A;  2DSI A;  2PCK A;  2PCA A;  2ELD A;  2PCI A;  3KE8 A;  2P6L A;  4MV5 A;  2NPN A;  2ED3 A;  3T0F A;  2HUQ A;  2OWK A;  2E4N A;  2DEK A;  2DV3 A;  2HUX A;  2P9D A;  3ZGN A;  2EL0 A;  3NDC A;  3KWP A;  3I4T A;  2PB5 A;  2DV4 A;  1VCE A;  2QBU A;  1CBF A;  2E08 A;  2DXV A;  2ED5 A;  4MV0 A;  3UV7 A;  4N7B A;  3DNF A;  1WYZ A;  2E8H A;  2EGS A;  5HW4 A;  2EH2 A;  2DV7 A;  3F7T A;  2ELE A;  2EJK A;  2EHC A;  2Z6R A;  1VHV A;  2E15 A;  3NUT A;  1V9A A;  2ZVC A;  3SZL A;  2BB3 A;  2OWU A;  4H4C A;  2EHL A;  3SZO A;  3LMM A;  2P2X A;  3KE9 A;  2EGL A;  2DSH A;  2E16 A;  4H4E A;  3SZU A;  3UV6 A;  2HUT A;  2EJJ A;  2P6I A;  3KEF A;  2PCG A;  1PJQ A;  2EN5 A;  2E0K A;  2E17 A;  3NEI A;  2KYY A;  2PB4 A;  2EK3 A;  4H4D A;  2EH5 A;  2PCH A;  2EK7 A;  2E8S A;  2EEQ A;  2EGB A;  2P6D A;  1VA0 A;  2P6K A;  2P5C A;  2EK2 A;  4MUX A;  4EB3 A;  2EK4 A;  2E07 A;  2E8R A;  1PJT A;  2EL2 A;  2PCM A;  2ZVB A;  3KEM A;  2OWG A;  3UTC A;  3KEL A;  3UTD A;  2EH4 A;  2OWV A;  2DSG A;  1WNG A;  2YBQ A;  2E0N A;  3URK A;  1S4D A;  3ND1 A;  3HH1 A; 
#chains in the Genus database with same CATH homology
 3T0G A;  4MUY A;  2E8Q A;  2EMU A;  2EMR A;  2HUV A;  2DXX A;  2OWF A;  2DV5 A;  2YBO A;  1PJS A;  4E16 A;  2PB6 A;  3UWM A;  2E7R A;  3FFY A;  2EL1 A;  3FQ6 A;  2P5F A;  1WDE A;  1VE2 A;  2EJZ A;  3TIX B;  2DXW A;  2E4R A;  3UV3 A;  2ENI A;  3ZGL A;  2EL3 A;  2HR8 A;  2EKA A;  2CBF A;  2DSI A;  2PCK A;  2PCA A;  2ELD A;  2PCI A;  3KE8 A;  2P6L A;  4MV5 A;  2NPN A;  2ED3 A;  3T0F A;  2HUQ A;  2OWK A;  2E4N A;  2DEK A;  2DV3 A;  2HUX A;  2P9D A;  3ZGN A;  2EL0 A;  3NDC A;  3KWP A;  3I4T A;  2PB5 A;  2DV4 A;  1VCE A;  2QBU A;  1CBF A;  2E08 A;  2DXV A;  2ED5 A;  4MV0 A;  3UV7 A;  4N7B A;  3DNF A;  1WYZ A;  2E8H A;  2EGS A;  5HW4 A;  2EH2 A;  2DV7 A;  3F7T A;  2ELE A;  2EJK A;  2EHC A;  2Z6R A;  1VHV A;  2E15 A;  3NUT A;  1V9A A;  2ZVC A;  3SZL A;  2BB3 A;  2OWU A;  4H4C A;  2EHL A;  3SZO A;  3LMM A;  2P2X A;  3KE9 A;  2EGL A;  2DSH A;  2E16 A;  4H4E A;  3SZU A;  3UV6 A;  2HUT A;  2EJJ A;  2P6I A;  3KEF A;  2PCG A;  1PJQ A;  2EN5 A;  2E0K A;  2E17 A;  3NEI A;  2KYY A;  2PB4 A;  2EK3 A;  4H4D A;  2EH5 A;  2PCH A;  2EK7 A;  2E8S A;  2EEQ A;  2EGB A;  2P6D A;  1VA0 A;  2P6K A;  2P5C A;  2EK2 A;  4MUX A;  4EB3 A;  2EK4 A;  2E07 A;  2E8R A;  1PJT A;  2EL2 A;  2PCM A;  2ZVB A;  3KEM A;  2OWG A;  3UTC A;  3KEL A;  3UTD A;  2EH4 A;  2OWV A;  2DSG A;  1WNG A;  2YBQ A;  2E0N A;  3URK A;  1S4D A;  3ND1 A;  3HH1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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