2E15A

Crystal structure of arg173 to asn mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKNMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e15A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e15A01
2DV7A 2HUXA 2EMUA 2EH4A 1VHVA 2EL2A 2ELDA 2EL3A 4E16A 2PCGA 2E8RA 1PJQA 3NUTA 2E8SA 2EGBA 2EGSA 2PCIA 2EJZA 2P2XA 2P9DA 2EHCA 2DXXA 2ED3A 2E8QA 1WYZA 2NPNA 2E4NA 2EK3A 2OWKA 2P5CA 3FQ6A 2EK7A 2PB4A 2PCKA 1PJTA 2DV3A 2E4RA 2EEQA 2E07A 1WNGA 2DV4A 2PB6A 2DEKA 2ZVBA 2EH2A 2YBQA 2E7RA 2ED5A 3KWPA 2QBUA 2YBOA 2E16A 2PB5A 3ND1A 2EL1A 2DSGA 2EL0A 2HUTA 3I4TA 3FFYA 2ELEA 2EK2A 2EKAA 2HUQA 2DXVA 2EJKA 2P6LA 3NDCA 2P5FA 2P6KA 2EHLA 1WDEA 2CBFA 1PJSA 2DSHA 2EH5A 3HH1A 2BB3A 1VA0A 2HUVA 2E0KA 2E0NA 2OWVA 2E17A 2Z6RA 1S4DA 2OWUA 2DSIA 2E15A 3NEIA 2PCMA 1VCEA 2EK4A 5HW4A 2DV5A 2HR8A 2P6IA 2ENIA 2E08A 2OWGA 1CBFA 2EJJA 2EMRA 2PCHA 2ZVCA 2P6DA 2EN5A 2PCAA 2EGLA 2E8HA 2DXWA 1VE2A 1V9AA 2OWFA
chains in the Genus database with same CATH superfamily
2DV7A 3KE9A 2HUXA 2EMUA 2EH4A 3F7TA 3KELA 1VHVA 2EL2A 2ELDA 2EL3A 4E16A 3UV7A 4EB3A 2PCGA 2E8RA 1PJQA 3NUTA 2E8SA 2EGBA 2EGSA 3UTCA 3UTDA 2PCIA 2EJZA 2P2XA 2P9DA 2EHCA 2DXXA 4MUYA 2ED3A 2E8QA 1WYZA 2NPNA 3KEMA 2E4NA 2EK3A 2OWKA 2P5CA 3FQ6A 2EK7A 4MV5A 2PB4A 2PCKA 1PJTA 2DV3A 2E4RA 2EEQA 2E07A 3KEFA 1WNGA 2DV4A 3T0GA 2PB6A 2DEKA 2ZVBA 2EH2A 2YBQA 2E7RA 2ED5A 3KWPA 3SZUA 2QBUA 2YBOA 2E16A 3KE8A 2PB5A 3ND1A 2EL1A 2DSGA 4MV0A 2EL0A 2HUTA 4H4CA 3I4TA 3FFYA 2ELEA 2EK2A 2EKAA 2HUQA 2DXVA 3UV3A 2EJKA 2P6LA 3NDCA 2P5FA 3LMMA 2P6KA 4MUXA 2EHLA 1WDEA 2KYYA 2CBFA 1PJSA 4N7BA 2DSHA 2EH5A 3HH1A 2BB3A 1VA0A 2HUVA 3UV6A 2E0KA 3DNFA 2E0NA 2OWVA 2E17A 2Z6RA 4H4EA 1S4DA 2OWUA 2DSIA 2E15A 3NEIA 2PCMA 1VCEA 4H4DA 2EK4A 5HW4A 2DV5A 2HR8A 3SZLA 2P6IA 3TIXB 3URKA 3UWMA 2ENIA 2E08A 2OWGA 3SZOA 1CBFA 2EJJA 2EMRA 3T0FA 2PCHA 2ZVCA 2P6DA 2EN5A 2PCAA 2EGLA 3ZGLA 2E8HA 3ZGNA 2DXWA 1VE2A 1V9AA 2OWFA
chains in the Genus database with same CATH topology
2DV7A 3KE9A 2HUXA 2EMUA 2EH4A 3F7TA 3KELA 1VHVA 2EL2A 2ELDA 2EL3A 4E16A 3UV7A 4EB3A 2PCGA 2E8RA 1PJQA 3NUTA 2E8SA 2EGBA 2EGSA 3UTCA 3UTDA 2PCIA 2EJZA 2P2XA 2P9DA 2EHCA 2DXXA 4MUYA 2ED3A 2E8QA 1WYZA 2NPNA 3KEMA 2E4NA 2EK3A 2OWKA 2P5CA 3FQ6A 2EK7A 4MV5A 2PB4A 2PCKA 1PJTA 2DV3A 2E4RA 2EEQA 2E07A 3KEFA 1WNGA 2DV4A 3T0GA 2PB6A 2DEKA 2ZVBA 2EH2A 2YBQA 2E7RA 2ED5A 3KWPA 3SZUA 2QBUA 2YBOA 2E16A 3KE8A 2PB5A 3ND1A 2EL1A 2DSGA 4MV0A 2EL0A 2HUTA 4H4CA 3I4TA 3FFYA 2ELEA 2EK2A 2EKAA 2HUQA 2DXVA 3UV3A 2EJKA 2P6LA 3NDCA 2P5FA 3LMMA 2P6KA 4MUXA 2EHLA 1WDEA 2KYYA 2CBFA 1PJSA 4N7BA 2DSHA 2EH5A 3HH1A 2BB3A 1VA0A 2HUVA 3UV6A 2E0KA 3DNFA 2E0NA 2OWVA 2E17A 2Z6RA 4H4EA 1S4DA 2OWUA 2DSIA 2E15A 3NEIA 2PCMA 1VCEA 4H4DA 2EK4A 5HW4A 2DV5A 2HR8A 3SZLA 2P6IA 3TIXB 3URKA 3UWMA 2ENIA 2E08A 2OWGA 3SZOA 1CBFA 2EJJA 2EMRA 3T0FA 2PCHA 2ZVCA 2P6DA 2EN5A 2PCAA 2EGLA 3ZGLA 2E8HA 3ZGNA 2DXWA 1VE2A 1V9AA 2OWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DV7 A;  2HUX A;  2EMU A;  2EH4 A;  1VHV A;  2EL2 A;  2ELD A;  2EL3 A;  4E16 A;  2PCG A;  2E8R A;  1PJQ A;  3NUT A;  2E8S A;  2EGB A;  2EGS A;  2PCI A;  2EJZ A;  2P2X A;  2P9D A;  2EHC A;  2DXX A;  2ED3 A;  2E8Q A;  1WYZ A;  2NPN A;  2E4N A;  2EK3 A;  2OWK A;  2P5C A;  3FQ6 A;  2EK7 A;  2PB4 A;  2PCK A;  1PJT A;  2DV3 A;  2E4R A;  2EEQ A;  2E07 A;  1WNG A;  2DV4 A;  2PB6 A;  2DEK A;  2ZVB A;  2EH2 A;  2YBQ A;  2E7R A;  2ED5 A;  3KWP A;  2QBU A;  2YBO A;  2E16 A;  2PB5 A;  3ND1 A;  2EL1 A;  2DSG A;  2EL0 A;  2HUT A;  3I4T A;  3FFY A;  2ELE A;  2EK2 A;  2EKA A;  2HUQ A;  2DXV A;  2EJK A;  2P6L A;  3NDC A;  2P5F A;  2P6K A;  2EHL A;  1WDE A;  2CBF A;  1PJS A;  2DSH A;  2EH5 A;  3HH1 A;  2BB3 A;  1VA0 A;  2HUV A;  2E0K A;  2E0N A;  2OWV A;  2E17 A;  2Z6R A;  1S4D A;  2OWU A;  2DSI A;  2E15 A;  3NEI A;  2PCM A;  1VCE A;  2EK4 A;  5HW4 A;  2DV5 A;  2HR8 A;  2P6I A;  2ENI A;  2E08 A;  2OWG A;  1CBF A;  2EJJ A;  2EMR A;  2PCH A;  2ZVC A;  2P6D A;  2EN5 A;  2PCA A;  2EGL A;  2E8H A;  2DXW A;  1VE2 A;  1V9A A;  2OWF A; 
#chains in the Genus database with same CATH topology
 2DV7 A;  3KE9 A;  2HUX A;  2EMU A;  2EH4 A;  3F7T A;  3KEL A;  1VHV A;  2EL2 A;  2ELD A;  2EL3 A;  4E16 A;  3UV7 A;  4EB3 A;  2PCG A;  2E8R A;  1PJQ A;  3NUT A;  2E8S A;  2EGB A;  2EGS A;  3UTC A;  3UTD A;  2PCI A;  2EJZ A;  2P2X A;  2P9D A;  2EHC A;  2DXX A;  4MUY A;  2ED3 A;  2E8Q A;  1WYZ A;  2NPN A;  3KEM A;  2E4N A;  2EK3 A;  2OWK A;  2P5C A;  3FQ6 A;  2EK7 A;  4MV5 A;  2PB4 A;  2PCK A;  1PJT A;  2DV3 A;  2E4R A;  2EEQ A;  2E07 A;  3KEF A;  1WNG A;  2DV4 A;  3T0G A;  2PB6 A;  2DEK A;  2ZVB A;  2EH2 A;  2YBQ A;  2E7R A;  2ED5 A;  3KWP A;  3SZU A;  2QBU A;  2YBO A;  2E16 A;  3KE8 A;  2PB5 A;  3ND1 A;  2EL1 A;  2DSG A;  4MV0 A;  2EL0 A;  2HUT A;  4H4C A;  3I4T A;  3FFY A;  2ELE A;  2EK2 A;  2EKA A;  2HUQ A;  2DXV A;  3UV3 A;  2EJK A;  2P6L A;  3NDC A;  2P5F A;  3LMM A;  2P6K A;  4MUX A;  2EHL A;  1WDE A;  2KYY A;  2CBF A;  1PJS A;  4N7B A;  2DSH A;  2EH5 A;  3HH1 A;  2BB3 A;  1VA0 A;  2HUV A;  3UV6 A;  2E0K A;  3DNF A;  2E0N A;  2OWV A;  2E17 A;  2Z6R A;  4H4E A;  1S4D A;  2OWU A;  2DSI A;  2E15 A;  3NEI A;  2PCM A;  1VCE A;  4H4D A;  2EK4 A;  5HW4 A;  2DV5 A;  2HR8 A;  3SZL A;  2P6I A;  3TIX B;  3URK A;  3UWM A;  2ENI A;  2E08 A;  2OWG A;  3SZO A;  1CBF A;  2EJJ A;  2EMR A;  3T0F A;  2PCH A;  2ZVC A;  2P6D A;  2EN5 A;  2PCA A;  2EGL A;  3ZGL A;  2E8H A;  3ZGN A;  2DXW A;  1VE2 A;  1V9A A;  2OWF A; 
#chains in the Genus database with same CATH homology
 2DV7 A;  3KE9 A;  2HUX A;  2EMU A;  2EH4 A;  3F7T A;  3KEL A;  1VHV A;  2EL2 A;  2ELD A;  2EL3 A;  4E16 A;  3UV7 A;  4EB3 A;  2PCG A;  2E8R A;  1PJQ A;  3NUT A;  2E8S A;  2EGB A;  2EGS A;  3UTC A;  3UTD A;  2PCI A;  2EJZ A;  2P2X A;  2P9D A;  2EHC A;  2DXX A;  4MUY A;  2ED3 A;  2E8Q A;  1WYZ A;  2NPN A;  3KEM A;  2E4N A;  2EK3 A;  2OWK A;  2P5C A;  3FQ6 A;  2EK7 A;  4MV5 A;  2PB4 A;  2PCK A;  1PJT A;  2DV3 A;  2E4R A;  2EEQ A;  2E07 A;  3KEF A;  1WNG A;  2DV4 A;  3T0G A;  2PB6 A;  2DEK A;  2ZVB A;  2EH2 A;  2YBQ A;  2E7R A;  2ED5 A;  3KWP A;  3SZU A;  2QBU A;  2YBO A;  2E16 A;  3KE8 A;  2PB5 A;  3ND1 A;  2EL1 A;  2DSG A;  4MV0 A;  2EL0 A;  2HUT A;  4H4C A;  3I4T A;  3FFY A;  2ELE A;  2EK2 A;  2EKA A;  2HUQ A;  2DXV A;  3UV3 A;  2EJK A;  2P6L A;  3NDC A;  2P5F A;  3LMM A;  2P6K A;  4MUX A;  2EHL A;  1WDE A;  2KYY A;  2CBF A;  1PJS A;  4N7B A;  2DSH A;  2EH5 A;  3HH1 A;  2BB3 A;  1VA0 A;  2HUV A;  3UV6 A;  2E0K A;  3DNF A;  2E0N A;  2OWV A;  2E17 A;  2Z6R A;  4H4E A;  1S4D A;  2OWU A;  2DSI A;  2E15 A;  3NEI A;  2PCM A;  1VCE A;  4H4D A;  2EK4 A;  5HW4 A;  2DV5 A;  2HR8 A;  3SZL A;  2P6I A;  3TIX B;  3URK A;  3UWM A;  2ENI A;  2E08 A;  2OWG A;  3SZO A;  1CBF A;  2EJJ A;  2EMR A;  3T0F A;  2PCH A;  2ZVC A;  2P6D A;  2EN5 A;  2PCA A;  2EGL A;  3ZGL A;  2E8H A;  3ZGN A;  2DXW A;  1VE2 A;  1V9A A;  2OWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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