2EHCA

Crystal structure of asn69 to lys mutant of diphthine synthase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFEKIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 82
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2ehcA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2ehcA01
2EGLA 2ELDA 2EEQA 2P6LA 2BB3A 2EKAA 2OWFA 2EGSA 2DXXA 2E15A 2EMRA 2P9DA 5HW4A 2OWVA 2PCAA 2DV4A 2E16A 2DEKA 2P5CA 2EJZA 2E08A 3NDCA 1S4DA 2HUQA 3HH1A 2OWUA 2E4RA 1VE2A 2YBQA 3FQ6A 2EH4A 3I4TA 2EL1A 2PB4A 2DSGA 1WYZA 2E8HA 2P6IA 1WDEA 2P5FA 1PJTA 1VA0A 2P6KA 2EK4A 2EK3A 4E16A 2EL2A 2E4NA 2HUXA 2ED3A 2QBUA 2EL0A 2OWKA 2ZVBA 2EK2A 2DV3A 2NPNA 2EJKA 2HUVA 2PCGA 2PCKA 2CBFA 2YBOA 2EMUA 2E0NA 2E8QA 2ENIA 2E8SA 2EH5A 3ND1A 3NUTA 2ED5A 2Z6RA 1CBFA 2DV7A 2E8RA 2EGBA 1V9AA 2EK7A 1PJQA 2EL3A 2P2XA 2E0KA 2E07A 2EJJA 1WNGA 2OWGA 2ELEA 2PB5A 2EN5A 1VCEA 3NEIA 2DXWA 2PCIA 1PJSA 1VHVA 2DSIA 2P6DA 2DSHA 2E17A 2DV5A 2EHCA 2E7RA 2DXVA 3KWPA 2EHLA 2EH2A 3FFYA 2PB6A 2HR8A 2HUTA 2ZVCA 2PCMA 2PCHA
chains in the Genus database with same CATH superfamily
2EGLA 2ELDA 2EEQA 4H4CA 2P6LA 2BB3A 2EKAA 2OWFA 2EGSA 3F7TA 2DXXA 2E15A 2EMRA 2P9DA 3UV3A 5HW4A 2OWVA 2PCAA 2DV4A 2E16A 2DEKA 2P5CA 2EJZA 2E08A 3NDCA 1S4DA 2HUQA 3HH1A 3KEMA 2OWUA 2E4RA 1VE2A 2YBQA 3FQ6A 3SZOA 4MV0A 2EH4A 3LMMA 3I4TA 2EL1A 2PB4A 2DSGA 1WYZA 2E8HA 2P6IA 1WDEA 3UV6A 2P5FA 3KE9A 3UV7A 1PJTA 1VA0A 2P6KA 3UTCA 2EK4A 2EK3A 4E16A 2EL2A 2E4NA 2HUXA 2ED3A 4MUXA 3ZGNA 2QBUA 2EL0A 3TIXB 2OWKA 2ZVBA 2EK2A 2DV3A 2NPNA 2EJKA 2HUVA 2PCGA 3SZUA 2PCKA 4MUYA 2CBFA 2YBOA 2KYYA 2EMUA 2E0NA 2E8QA 2ENIA 2E8SA 4EB3A 2EH5A 3ND1A 3KE8A 3NUTA 2ED5A 2Z6RA 4MV5A 1CBFA 2DV7A 2E8RA 2EGBA 1V9AA 2EK7A 1PJQA 3T0FA 3ZGLA 2EL3A 3SZLA 4H4DA 2P2XA 2E0KA 3UTDA 2E07A 2EJJA 1WNGA 2OWGA 2ELEA 2PB5A 2EN5A 1VCEA 3NEIA 2DXWA 2PCIA 3URKA 1PJSA 4H4EA 1VHVA 2DSIA 2P6DA 3T0GA 2DSHA 2E17A 2DV5A 2EHCA 4N7BA 3KELA 2E7RA 2DXVA 3KWPA 2EHLA 3UWMA 2EH2A 3FFYA 2PB6A 3KEFA 2HR8A 3DNFA 2HUTA 2ZVCA 2PCMA 2PCHA
chains in the Genus database with same CATH topology
2EGLA 2ELDA 2EEQA 4H4CA 2P6LA 2BB3A 2EKAA 2OWFA 2EGSA 3F7TA 2DXXA 2E15A 2EMRA 2P9DA 3UV3A 5HW4A 2OWVA 2PCAA 2DV4A 2E16A 2DEKA 2P5CA 2EJZA 2E08A 3NDCA 1S4DA 2HUQA 3HH1A 3KEMA 2OWUA 2E4RA 1VE2A 2YBQA 3FQ6A 3SZOA 4MV0A 2EH4A 3LMMA 3I4TA 2EL1A 2PB4A 2DSGA 1WYZA 2E8HA 2P6IA 1WDEA 3UV6A 2P5FA 3KE9A 3UV7A 1PJTA 1VA0A 2P6KA 3UTCA 2EK4A 2EK3A 4E16A 2EL2A 2E4NA 2HUXA 2ED3A 4MUXA 3ZGNA 2QBUA 2EL0A 3TIXB 2OWKA 2ZVBA 2EK2A 2DV3A 2NPNA 2EJKA 2HUVA 2PCGA 3SZUA 2PCKA 4MUYA 2CBFA 2YBOA 2KYYA 2EMUA 2E0NA 2E8QA 2ENIA 2E8SA 4EB3A 2EH5A 3ND1A 3KE8A 3NUTA 2ED5A 2Z6RA 4MV5A 1CBFA 2DV7A 2E8RA 2EGBA 1V9AA 2EK7A 1PJQA 3T0FA 3ZGLA 2EL3A 3SZLA 4H4DA 2P2XA 2E0KA 3UTDA 2E07A 2EJJA 1WNGA 2OWGA 2ELEA 2PB5A 2EN5A 1VCEA 3NEIA 2DXWA 2PCIA 3URKA 1PJSA 4H4EA 1VHVA 2DSIA 2P6DA 3T0GA 2DSHA 2E17A 2DV5A 2EHCA 4N7BA 3KELA 2E7RA 2DXVA 3KWPA 2EHLA 3UWMA 2EH2A 3FFYA 2PB6A 3KEFA 2HR8A 3DNFA 2HUTA 2ZVCA 2PCMA 2PCHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EGL A;  2ELD A;  2EEQ A;  2P6L A;  2BB3 A;  2EKA A;  2OWF A;  2EGS A;  2DXX A;  2E15 A;  2EMR A;  2P9D A;  5HW4 A;  2OWV A;  2PCA A;  2DV4 A;  2E16 A;  2DEK A;  2P5C A;  2EJZ A;  2E08 A;  3NDC A;  1S4D A;  2HUQ A;  3HH1 A;  2OWU A;  2E4R A;  1VE2 A;  2YBQ A;  3FQ6 A;  2EH4 A;  3I4T A;  2EL1 A;  2PB4 A;  2DSG A;  1WYZ A;  2E8H A;  2P6I A;  1WDE A;  2P5F A;  1PJT A;  1VA0 A;  2P6K A;  2EK4 A;  2EK3 A;  4E16 A;  2EL2 A;  2E4N A;  2HUX A;  2ED3 A;  2QBU A;  2EL0 A;  2OWK A;  2ZVB A;  2EK2 A;  2DV3 A;  2NPN A;  2EJK A;  2HUV A;  2PCG A;  2PCK A;  2CBF A;  2YBO A;  2EMU A;  2E0N A;  2E8Q A;  2ENI A;  2E8S A;  2EH5 A;  3ND1 A;  3NUT A;  2ED5 A;  2Z6R A;  1CBF A;  2DV7 A;  2E8R A;  2EGB A;  1V9A A;  2EK7 A;  1PJQ A;  2EL3 A;  2P2X A;  2E0K A;  2E07 A;  2EJJ A;  1WNG A;  2OWG A;  2ELE A;  2PB5 A;  2EN5 A;  1VCE A;  3NEI A;  2DXW A;  2PCI A;  1PJS A;  1VHV A;  2DSI A;  2P6D A;  2DSH A;  2E17 A;  2DV5 A;  2EHC A;  2E7R A;  2DXV A;  3KWP A;  2EHL A;  2EH2 A;  3FFY A;  2PB6 A;  2HR8 A;  2HUT A;  2ZVC A;  2PCM A;  2PCH A; 
#chains in the Genus database with same CATH topology
 2EGL A;  2ELD A;  2EEQ A;  4H4C A;  2P6L A;  2BB3 A;  2EKA A;  2OWF A;  2EGS A;  3F7T A;  2DXX A;  2E15 A;  2EMR A;  2P9D A;  3UV3 A;  5HW4 A;  2OWV A;  2PCA A;  2DV4 A;  2E16 A;  2DEK A;  2P5C A;  2EJZ A;  2E08 A;  3NDC A;  1S4D A;  2HUQ A;  3HH1 A;  3KEM A;  2OWU A;  2E4R A;  1VE2 A;  2YBQ A;  3FQ6 A;  3SZO A;  4MV0 A;  2EH4 A;  3LMM A;  3I4T A;  2EL1 A;  2PB4 A;  2DSG A;  1WYZ A;  2E8H A;  2P6I A;  1WDE A;  3UV6 A;  2P5F A;  3KE9 A;  3UV7 A;  1PJT A;  1VA0 A;  2P6K A;  3UTC A;  2EK4 A;  2EK3 A;  4E16 A;  2EL2 A;  2E4N A;  2HUX A;  2ED3 A;  4MUX A;  3ZGN A;  2QBU A;  2EL0 A;  3TIX B;  2OWK A;  2ZVB A;  2EK2 A;  2DV3 A;  2NPN A;  2EJK A;  2HUV A;  2PCG A;  3SZU A;  2PCK A;  4MUY A;  2CBF A;  2YBO A;  2KYY A;  2EMU A;  2E0N A;  2E8Q A;  2ENI A;  2E8S A;  4EB3 A;  2EH5 A;  3ND1 A;  3KE8 A;  3NUT A;  2ED5 A;  2Z6R A;  4MV5 A;  1CBF A;  2DV7 A;  2E8R A;  2EGB A;  1V9A A;  2EK7 A;  1PJQ A;  3T0F A;  3ZGL A;  2EL3 A;  3SZL A;  4H4D A;  2P2X A;  2E0K A;  3UTD A;  2E07 A;  2EJJ A;  1WNG A;  2OWG A;  2ELE A;  2PB5 A;  2EN5 A;  1VCE A;  3NEI A;  2DXW A;  2PCI A;  3URK A;  1PJS A;  4H4E A;  1VHV A;  2DSI A;  2P6D A;  3T0G A;  2DSH A;  2E17 A;  2DV5 A;  2EHC A;  4N7B A;  3KEL A;  2E7R A;  2DXV A;  3KWP A;  2EHL A;  3UWM A;  2EH2 A;  3FFY A;  2PB6 A;  3KEF A;  2HR8 A;  3DNF A;  2HUT A;  2ZVC A;  2PCM A;  2PCH A; 
#chains in the Genus database with same CATH homology
 2EGL A;  2ELD A;  2EEQ A;  4H4C A;  2P6L A;  2BB3 A;  2EKA A;  2OWF A;  2EGS A;  3F7T A;  2DXX A;  2E15 A;  2EMR A;  2P9D A;  3UV3 A;  5HW4 A;  2OWV A;  2PCA A;  2DV4 A;  2E16 A;  2DEK A;  2P5C A;  2EJZ A;  2E08 A;  3NDC A;  1S4D A;  2HUQ A;  3HH1 A;  3KEM A;  2OWU A;  2E4R A;  1VE2 A;  2YBQ A;  3FQ6 A;  3SZO A;  4MV0 A;  2EH4 A;  3LMM A;  3I4T A;  2EL1 A;  2PB4 A;  2DSG A;  1WYZ A;  2E8H A;  2P6I A;  1WDE A;  3UV6 A;  2P5F A;  3KE9 A;  3UV7 A;  1PJT A;  1VA0 A;  2P6K A;  3UTC A;  2EK4 A;  2EK3 A;  4E16 A;  2EL2 A;  2E4N A;  2HUX A;  2ED3 A;  4MUX A;  3ZGN A;  2QBU A;  2EL0 A;  3TIX B;  2OWK A;  2ZVB A;  2EK2 A;  2DV3 A;  2NPN A;  2EJK A;  2HUV A;  2PCG A;  3SZU A;  2PCK A;  4MUY A;  2CBF A;  2YBO A;  2KYY A;  2EMU A;  2E0N A;  2E8Q A;  2ENI A;  2E8S A;  4EB3 A;  2EH5 A;  3ND1 A;  3KE8 A;  3NUT A;  2ED5 A;  2Z6R A;  4MV5 A;  1CBF A;  2DV7 A;  2E8R A;  2EGB A;  1V9A A;  2EK7 A;  1PJQ A;  3T0F A;  3ZGL A;  2EL3 A;  3SZL A;  4H4D A;  2P2X A;  2E0K A;  3UTD A;  2E07 A;  2EJJ A;  1WNG A;  2OWG A;  2ELE A;  2PB5 A;  2EN5 A;  1VCE A;  3NEI A;  2DXW A;  2PCI A;  3URK A;  1PJS A;  4H4E A;  1VHV A;  2DSI A;  2P6D A;  3T0G A;  2DSH A;  2E17 A;  2DV5 A;  2EHC A;  4N7B A;  3KEL A;  2E7R A;  2DXV A;  3KWP A;  2EHL A;  3UWM A;  2EH2 A;  3FFY A;  2PB6 A;  3KEF A;  2HR8 A;  3DNF A;  2HUT A;  2ZVC A;  2PCM A;  2PCH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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