2E17A

Crystal structure of arg173 to ala mutant of diphthine synthase
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKAMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords Probable diphthine synthase
total genus 84
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e17A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e17A01
2ED5A 2YBQA 2HUVA 2YBOA 2P5FA 2E8SA 2P2XA 2PCMA 2ELEA 2PCAA 1WYZA 3NEIA 2EJKA 1VHVA 1PJSA 2PCIA 2E16A 2BB3A 2E07A 2P6IA 2E17A 2PCKA 4E16A 2PB4A 2E8RA 2EK2A 2DXVA 2EGSA 2EH4A 2EHLA 2DSIA 1VCEA 2ZVCA 2E4RA 2DV4A 3I4TA 2EMRA 2EEQA 1PJQA 2EK3A 2P9DA 2HUTA 2ELDA 2EN5A 2P5CA 2ED3A 3NDCA 2DSHA 2P6DA 2EL1A 2HUXA 2PB6A 2DV5A 2EH5A 2OWKA 2DXXA 2OWVA 1VA0A 2E08A 2HR8A 2DV7A 2E4NA 1V9AA 2EL3A 2EK4A 2DV3A 2P6LA 2P6KA 2ENIA 2PB5A 2DEKA 3ND1A 2OWGA 1PJTA 3FQ6A 3KWPA 2E7RA 3NUTA 2DXWA 1WDEA 2NPNA 2EKAA 2E0KA 2PCGA 2EK7A 2OWFA 2E8QA 2PCHA 2EMUA 2EJJA 3HH1A 2EGLA 2Z6RA 2E15A 1WNGA 1S4DA 2QBUA 5HW4A 2EH2A 2E8HA 2E0NA 2HUQA 2EJZA 1VE2A 2EL2A 2CBFA 2DSGA 1CBFA 2EL0A 2EGBA 2EHCA 3FFYA 2ZVBA 2OWUA
chains in the Genus database with same CATH superfamily
2ED5A 2YBQA 2HUVA 2YBOA 2P5FA 4H4CA 2E8SA 2P2XA 2PCMA 2ELEA 2PCAA 4MV0A 1WYZA 3UV3A 3NEIA 2EJKA 1VHVA 1PJSA 3SZLA 2PCIA 2E16A 3F7TA 4MV5A 4EB3A 2BB3A 2E07A 2P6IA 2E17A 2PCKA 4E16A 3UV7A 2PB4A 3KEFA 2E8RA 2EK2A 2DXVA 2EGSA 2EH4A 2EHLA 2DSIA 4MUYA 1VCEA 2ZVCA 2E4RA 2DV4A 3I4TA 2EMRA 2EEQA 4H4EA 1PJQA 3UV6A 2EK3A 2P9DA 2HUTA 2ELDA 3KE8A 2EN5A 2P5CA 3KE9A 2ED3A 3NDCA 2DSHA 2P6DA 2EL1A 2HUXA 3ZGNA 2PB6A 2DV5A 2EH5A 2OWKA 2DXXA 2OWVA 1VA0A 2E08A 2HR8A 2DV7A 3KEMA 3KELA 2E4NA 1V9AA 2EL3A 2EK4A 2DV3A 2P6LA 2P6KA 2ENIA 3SZUA 3SZOA 2PB5A 2DEKA 3ND1A 2OWGA 4H4DA 3UTCA 1PJTA 3URKA 3FQ6A 3KWPA 2E7RA 3NUTA 2DXWA 1WDEA 2NPNA 2EKAA 2E0KA 3TIXB 2PCGA 4N7BA 2EK7A 2OWFA 2E8QA 2PCHA 2EMUA 2EJJA 3HH1A 2EGLA 2Z6RA 3LMMA 2E15A 3UTDA 1WNGA 1S4DA 3T0FA 2QBUA 3T0GA 4MUXA 5HW4A 2EH2A 2E8HA 3DNFA 2E0NA 2HUQA 2KYYA 2EJZA 1VE2A 2EL2A 2CBFA 3UWMA 2DSGA 1CBFA 2EL0A 3ZGLA 2EGBA 2EHCA 3FFYA 2ZVBA 2OWUA
chains in the Genus database with same CATH topology
2ED5A 2YBQA 2HUVA 2YBOA 2P5FA 4H4CA 2E8SA 2P2XA 2PCMA 2ELEA 2PCAA 4MV0A 1WYZA 3UV3A 3NEIA 2EJKA 1VHVA 1PJSA 3SZLA 2PCIA 2E16A 3F7TA 4MV5A 4EB3A 2BB3A 2E07A 2P6IA 2E17A 2PCKA 4E16A 3UV7A 2PB4A 3KEFA 2E8RA 2EK2A 2DXVA 2EGSA 2EH4A 2EHLA 2DSIA 4MUYA 1VCEA 2ZVCA 2E4RA 2DV4A 3I4TA 2EMRA 2EEQA 4H4EA 1PJQA 3UV6A 2EK3A 2P9DA 2HUTA 2ELDA 3KE8A 2EN5A 2P5CA 3KE9A 2ED3A 3NDCA 2DSHA 2P6DA 2EL1A 2HUXA 3ZGNA 2PB6A 2DV5A 2EH5A 2OWKA 2DXXA 2OWVA 1VA0A 2E08A 2HR8A 2DV7A 3KEMA 3KELA 2E4NA 1V9AA 2EL3A 2EK4A 2DV3A 2P6LA 2P6KA 2ENIA 3SZUA 3SZOA 2PB5A 2DEKA 3ND1A 2OWGA 4H4DA 3UTCA 1PJTA 3URKA 3FQ6A 3KWPA 2E7RA 3NUTA 2DXWA 1WDEA 2NPNA 2EKAA 2E0KA 3TIXB 2PCGA 4N7BA 2EK7A 2OWFA 2E8QA 2PCHA 2EMUA 2EJJA 3HH1A 2EGLA 2Z6RA 3LMMA 2E15A 3UTDA 1WNGA 1S4DA 3T0FA 2QBUA 3T0GA 4MUXA 5HW4A 2EH2A 2E8HA 3DNFA 2E0NA 2HUQA 2KYYA 2EJZA 1VE2A 2EL2A 2CBFA 3UWMA 2DSGA 1CBFA 2EL0A 3ZGLA 2EGBA 2EHCA 3FFYA 2ZVBA 2OWUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ED5 A;  2YBQ A;  2HUV A;  2YBO A;  2P5F A;  2E8S A;  2P2X A;  2PCM A;  2ELE A;  2PCA A;  1WYZ A;  3NEI A;  2EJK A;  1VHV A;  1PJS A;  2PCI A;  2E16 A;  2BB3 A;  2E07 A;  2P6I A;  2E17 A;  2PCK A;  4E16 A;  2PB4 A;  2E8R A;  2EK2 A;  2DXV A;  2EGS A;  2EH4 A;  2EHL A;  2DSI A;  1VCE A;  2ZVC A;  2E4R A;  2DV4 A;  3I4T A;  2EMR A;  2EEQ A;  1PJQ A;  2EK3 A;  2P9D A;  2HUT A;  2ELD A;  2EN5 A;  2P5C A;  2ED3 A;  3NDC A;  2DSH A;  2P6D A;  2EL1 A;  2HUX A;  2PB6 A;  2DV5 A;  2EH5 A;  2OWK A;  2DXX A;  2OWV A;  1VA0 A;  2E08 A;  2HR8 A;  2DV7 A;  2E4N A;  1V9A A;  2EL3 A;  2EK4 A;  2DV3 A;  2P6L A;  2P6K A;  2ENI A;  2PB5 A;  2DEK A;  3ND1 A;  2OWG A;  1PJT A;  3FQ6 A;  3KWP A;  2E7R A;  3NUT A;  2DXW A;  1WDE A;  2NPN A;  2EKA A;  2E0K A;  2PCG A;  2EK7 A;  2OWF A;  2E8Q A;  2PCH A;  2EMU A;  2EJJ A;  3HH1 A;  2EGL A;  2Z6R A;  2E15 A;  1WNG A;  1S4D A;  2QBU A;  5HW4 A;  2EH2 A;  2E8H A;  2E0N A;  2HUQ A;  2EJZ A;  1VE2 A;  2EL2 A;  2CBF A;  2DSG A;  1CBF A;  2EL0 A;  2EGB A;  2EHC A;  3FFY A;  2ZVB A;  2OWU A; 
#chains in the Genus database with same CATH topology
 2ED5 A;  2YBQ A;  2HUV A;  2YBO A;  2P5F A;  4H4C A;  2E8S A;  2P2X A;  2PCM A;  2ELE A;  2PCA A;  4MV0 A;  1WYZ A;  3UV3 A;  3NEI A;  2EJK A;  1VHV A;  1PJS A;  3SZL A;  2PCI A;  2E16 A;  3F7T A;  4MV5 A;  4EB3 A;  2BB3 A;  2E07 A;  2P6I A;  2E17 A;  2PCK A;  4E16 A;  3UV7 A;  2PB4 A;  3KEF A;  2E8R A;  2EK2 A;  2DXV A;  2EGS A;  2EH4 A;  2EHL A;  2DSI A;  4MUY A;  1VCE A;  2ZVC A;  2E4R A;  2DV4 A;  3I4T A;  2EMR A;  2EEQ A;  4H4E A;  1PJQ A;  3UV6 A;  2EK3 A;  2P9D A;  2HUT A;  2ELD A;  3KE8 A;  2EN5 A;  2P5C A;  3KE9 A;  2ED3 A;  3NDC A;  2DSH A;  2P6D A;  2EL1 A;  2HUX A;  3ZGN A;  2PB6 A;  2DV5 A;  2EH5 A;  2OWK A;  2DXX A;  2OWV A;  1VA0 A;  2E08 A;  2HR8 A;  2DV7 A;  3KEM A;  3KEL A;  2E4N A;  1V9A A;  2EL3 A;  2EK4 A;  2DV3 A;  2P6L A;  2P6K A;  2ENI A;  3SZU A;  3SZO A;  2PB5 A;  2DEK A;  3ND1 A;  2OWG A;  4H4D A;  3UTC A;  1PJT A;  3URK A;  3FQ6 A;  3KWP A;  2E7R A;  3NUT A;  2DXW A;  1WDE A;  2NPN A;  2EKA A;  2E0K A;  3TIX B;  2PCG A;  4N7B A;  2EK7 A;  2OWF A;  2E8Q A;  2PCH A;  2EMU A;  2EJJ A;  3HH1 A;  2EGL A;  2Z6R A;  3LMM A;  2E15 A;  3UTD A;  1WNG A;  1S4D A;  3T0F A;  2QBU A;  3T0G A;  4MUX A;  5HW4 A;  2EH2 A;  2E8H A;  3DNF A;  2E0N A;  2HUQ A;  2KYY A;  2EJZ A;  1VE2 A;  2EL2 A;  2CBF A;  3UWM A;  2DSG A;  1CBF A;  2EL0 A;  3ZGL A;  2EGB A;  2EHC A;  3FFY A;  2ZVB A;  2OWU A; 
#chains in the Genus database with same CATH homology
 2ED5 A;  2YBQ A;  2HUV A;  2YBO A;  2P5F A;  4H4C A;  2E8S A;  2P2X A;  2PCM A;  2ELE A;  2PCA A;  4MV0 A;  1WYZ A;  3UV3 A;  3NEI A;  2EJK A;  1VHV A;  1PJS A;  3SZL A;  2PCI A;  2E16 A;  3F7T A;  4MV5 A;  4EB3 A;  2BB3 A;  2E07 A;  2P6I A;  2E17 A;  2PCK A;  4E16 A;  3UV7 A;  2PB4 A;  3KEF A;  2E8R A;  2EK2 A;  2DXV A;  2EGS A;  2EH4 A;  2EHL A;  2DSI A;  4MUY A;  1VCE A;  2ZVC A;  2E4R A;  2DV4 A;  3I4T A;  2EMR A;  2EEQ A;  4H4E A;  1PJQ A;  3UV6 A;  2EK3 A;  2P9D A;  2HUT A;  2ELD A;  3KE8 A;  2EN5 A;  2P5C A;  3KE9 A;  2ED3 A;  3NDC A;  2DSH A;  2P6D A;  2EL1 A;  2HUX A;  3ZGN A;  2PB6 A;  2DV5 A;  2EH5 A;  2OWK A;  2DXX A;  2OWV A;  1VA0 A;  2E08 A;  2HR8 A;  2DV7 A;  3KEM A;  3KEL A;  2E4N A;  1V9A A;  2EL3 A;  2EK4 A;  2DV3 A;  2P6L A;  2P6K A;  2ENI A;  3SZU A;  3SZO A;  2PB5 A;  2DEK A;  3ND1 A;  2OWG A;  4H4D A;  3UTC A;  1PJT A;  3URK A;  3FQ6 A;  3KWP A;  2E7R A;  3NUT A;  2DXW A;  1WDE A;  2NPN A;  2EKA A;  2E0K A;  3TIX B;  2PCG A;  4N7B A;  2EK7 A;  2OWF A;  2E8Q A;  2PCH A;  2EMU A;  2EJJ A;  3HH1 A;  2EGL A;  2Z6R A;  3LMM A;  2E15 A;  3UTD A;  1WNG A;  1S4D A;  3T0F A;  2QBU A;  3T0G A;  4MUX A;  5HW4 A;  2EH2 A;  2E8H A;  3DNF A;  2E0N A;  2HUQ A;  2KYY A;  2EJZ A;  1VE2 A;  2EL2 A;  2CBF A;  3UWM A;  2DSG A;  1CBF A;  2EL0 A;  3ZGL A;  2EGB A;  2EHC A;  3FFY A;  2ZVB A;  2OWU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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