2EH2A

Mutant v18m structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITMKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant V18M structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
molecule keywords diphthine synthase
total genus 85
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2eh2A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2eh2A01
1VCEA 2OWUA 2E17A 3I4TA 2OWVA 2OWKA 2EH4A 2E16A 3ND1A 2E0KA 3NUTA 2EMRA 2E08A 2BB3A 1WYZA 2E7RA 4E16A 2P6DA 2PCHA 2DSHA 2EK4A 2CBFA 2EJKA 2P2XA 2ZVCA 3FFYA 2E8SA 1VA0A 2YBQA 2EHCA 2E8QA 2PCIA 2ED5A 2E07A 1PJTA 1VHVA 1VE2A 2ENIA 2OWGA 2EH2A 2EN5A 1PJQA 2DV7A 2EEQA 2PB6A 3KWPA 1PJSA 2YBOA 2PCAA 2P6IA 2EKAA 2EJJA 3HH1A 2HUVA 2DXVA 1S4DA 2EL0A 2HR8A 2HUTA 2EL1A 2PCMA 5HW4A 2DXXA 2E8RA 2EGSA 2EL2A 2P6LA 3NDCA 2HUQA 3FQ6A 2EH5A 2ZVBA 2EMUA 2DV5A 2E0NA 2P5FA 2PB4A 2Z6RA 2EHLA 2EK3A 1V9AA 2OWFA 2EJZA 2ED3A 1WNGA 2DSGA 2PCGA 2DEKA 2P6KA 2ELEA 1WDEA 2PB5A 2E4RA 2EGLA 2DSIA 2EK2A 2P5CA 2QBUA 2ELDA 2NPNA 2P9DA 3NEIA 2E8HA 2DXWA 2EGBA 2DV3A 2E4NA 2HUXA 2PCKA 2EL3A 2EK7A 2DV4A 2E15A 1CBFA
chains in the Genus database with same CATH superfamily
1VCEA 2OWUA 2E17A 3I4TA 4H4DA 3UV6A 2OWVA 2OWKA 2EH4A 3ZGNA 2E16A 3ND1A 3UWMA 2E0KA 3T0GA 3NUTA 2EMRA 2E08A 4MV5A 2BB3A 1WYZA 2E7RA 4E16A 2P6DA 2PCHA 2DSHA 4H4EA 4MUXA 2EK4A 2CBFA 3KEMA 2EJKA 2P2XA 2ZVCA 3FFYA 2E8SA 1VA0A 3TIXB 2YBQA 3UTDA 2EHCA 2E8QA 2PCIA 3UTCA 2ED5A 2E07A 3DNFA 1PJTA 1VHVA 1VE2A 2ENIA 2OWGA 2EH2A 2EN5A 1PJQA 2DV7A 2EEQA 2PB6A 3KWPA 1PJSA 2YBOA 3SZUA 2PCAA 2P6IA 2EKAA 2EJJA 3HH1A 2HUVA 2DXVA 1S4DA 2EL0A 2HR8A 2HUTA 2EL1A 2PCMA 5HW4A 4N7BA 4EB3A 2DXXA 2E8RA 2EGSA 2KYYA 2EL2A 2P6LA 3NDCA 4MUYA 2HUQA 3FQ6A 2EH5A 2ZVBA 3LMMA 2EMUA 2DV5A 2E0NA 2P5FA 2PB4A 2Z6RA 2EHLA 2EK3A 1V9AA 2OWFA 2EJZA 4H4CA 2ED3A 3F7TA 1WNGA 2DSGA 2PCGA 2DEKA 2P6KA 2ELEA 1WDEA 2PB5A 3SZLA 2E4RA 2EGLA 3UV7A 2DSIA 2EK2A 2P5CA 2QBUA 2ELDA 2NPNA 2P9DA 3T0FA 3ZGLA 3KE8A 3SZOA 3NEIA 3KEFA 3KELA 2E8HA 2DXWA 2EGBA 2DV3A 2E4NA 2HUXA 2PCKA 4MV0A 2EL3A 3UV3A 3URKA 2EK7A 2DV4A 2E15A 3KE9A 1CBFA
chains in the Genus database with same CATH topology
1VCEA 2OWUA 2E17A 3I4TA 4H4DA 3UV6A 2OWVA 2OWKA 2EH4A 3ZGNA 2E16A 3ND1A 3UWMA 2E0KA 3T0GA 3NUTA 2EMRA 2E08A 4MV5A 2BB3A 1WYZA 2E7RA 4E16A 2P6DA 2PCHA 2DSHA 4H4EA 4MUXA 2EK4A 2CBFA 3KEMA 2EJKA 2P2XA 2ZVCA 3FFYA 2E8SA 1VA0A 3TIXB 2YBQA 3UTDA 2EHCA 2E8QA 2PCIA 3UTCA 2ED5A 2E07A 3DNFA 1PJTA 1VHVA 1VE2A 2ENIA 2OWGA 2EH2A 2EN5A 1PJQA 2DV7A 2EEQA 2PB6A 3KWPA 1PJSA 2YBOA 3SZUA 2PCAA 2P6IA 2EKAA 2EJJA 3HH1A 2HUVA 2DXVA 1S4DA 2EL0A 2HR8A 2HUTA 2EL1A 2PCMA 5HW4A 4N7BA 4EB3A 2DXXA 2E8RA 2EGSA 2KYYA 2EL2A 2P6LA 3NDCA 4MUYA 2HUQA 3FQ6A 2EH5A 2ZVBA 3LMMA 2EMUA 2DV5A 2E0NA 2P5FA 2PB4A 2Z6RA 2EHLA 2EK3A 1V9AA 2OWFA 2EJZA 4H4CA 2ED3A 3F7TA 1WNGA 2DSGA 2PCGA 2DEKA 2P6KA 2ELEA 1WDEA 2PB5A 3SZLA 2E4RA 2EGLA 3UV7A 2DSIA 2EK2A 2P5CA 2QBUA 2ELDA 2NPNA 2P9DA 3T0FA 3ZGLA 3KE8A 3SZOA 3NEIA 3KEFA 3KELA 2E8HA 2DXWA 2EGBA 2DV3A 2E4NA 2HUXA 2PCKA 4MV0A 2EL3A 3UV3A 3URKA 2EK7A 2DV4A 2E15A 3KE9A 1CBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VCE A;  2OWU A;  2E17 A;  3I4T A;  2OWV A;  2OWK A;  2EH4 A;  2E16 A;  3ND1 A;  2E0K A;  3NUT A;  2EMR A;  2E08 A;  2BB3 A;  1WYZ A;  2E7R A;  4E16 A;  2P6D A;  2PCH A;  2DSH A;  2EK4 A;  2CBF A;  2EJK A;  2P2X A;  2ZVC A;  3FFY A;  2E8S A;  1VA0 A;  2YBQ A;  2EHC A;  2E8Q A;  2PCI A;  2ED5 A;  2E07 A;  1PJT A;  1VHV A;  1VE2 A;  2ENI A;  2OWG A;  2EH2 A;  2EN5 A;  1PJQ A;  2DV7 A;  2EEQ A;  2PB6 A;  3KWP A;  1PJS A;  2YBO A;  2PCA A;  2P6I A;  2EKA A;  2EJJ A;  3HH1 A;  2HUV A;  2DXV A;  1S4D A;  2EL0 A;  2HR8 A;  2HUT A;  2EL1 A;  2PCM A;  5HW4 A;  2DXX A;  2E8R A;  2EGS A;  2EL2 A;  2P6L A;  3NDC A;  2HUQ A;  3FQ6 A;  2EH5 A;  2ZVB A;  2EMU A;  2DV5 A;  2E0N A;  2P5F A;  2PB4 A;  2Z6R A;  2EHL A;  2EK3 A;  1V9A A;  2OWF A;  2EJZ A;  2ED3 A;  1WNG A;  2DSG A;  2PCG A;  2DEK A;  2P6K A;  2ELE A;  1WDE A;  2PB5 A;  2E4R A;  2EGL A;  2DSI A;  2EK2 A;  2P5C A;  2QBU A;  2ELD A;  2NPN A;  2P9D A;  3NEI A;  2E8H A;  2DXW A;  2EGB A;  2DV3 A;  2E4N A;  2HUX A;  2PCK A;  2EL3 A;  2EK7 A;  2DV4 A;  2E15 A;  1CBF A; 
#chains in the Genus database with same CATH topology
 1VCE A;  2OWU A;  2E17 A;  3I4T A;  4H4D A;  3UV6 A;  2OWV A;  2OWK A;  2EH4 A;  3ZGN A;  2E16 A;  3ND1 A;  3UWM A;  2E0K A;  3T0G A;  3NUT A;  2EMR A;  2E08 A;  4MV5 A;  2BB3 A;  1WYZ A;  2E7R A;  4E16 A;  2P6D A;  2PCH A;  2DSH A;  4H4E A;  4MUX A;  2EK4 A;  2CBF A;  3KEM A;  2EJK A;  2P2X A;  2ZVC A;  3FFY A;  2E8S A;  1VA0 A;  3TIX B;  2YBQ A;  3UTD A;  2EHC A;  2E8Q A;  2PCI A;  3UTC A;  2ED5 A;  2E07 A;  3DNF A;  1PJT A;  1VHV A;  1VE2 A;  2ENI A;  2OWG A;  2EH2 A;  2EN5 A;  1PJQ A;  2DV7 A;  2EEQ A;  2PB6 A;  3KWP A;  1PJS A;  2YBO A;  3SZU A;  2PCA A;  2P6I A;  2EKA A;  2EJJ A;  3HH1 A;  2HUV A;  2DXV A;  1S4D A;  2EL0 A;  2HR8 A;  2HUT A;  2EL1 A;  2PCM A;  5HW4 A;  4N7B A;  4EB3 A;  2DXX A;  2E8R A;  2EGS A;  2KYY A;  2EL2 A;  2P6L A;  3NDC A;  4MUY A;  2HUQ A;  3FQ6 A;  2EH5 A;  2ZVB A;  3LMM A;  2EMU A;  2DV5 A;  2E0N A;  2P5F A;  2PB4 A;  2Z6R A;  2EHL A;  2EK3 A;  1V9A A;  2OWF A;  2EJZ A;  4H4C A;  2ED3 A;  3F7T A;  1WNG A;  2DSG A;  2PCG A;  2DEK A;  2P6K A;  2ELE A;  1WDE A;  2PB5 A;  3SZL A;  2E4R A;  2EGL A;  3UV7 A;  2DSI A;  2EK2 A;  2P5C A;  2QBU A;  2ELD A;  2NPN A;  2P9D A;  3T0F A;  3ZGL A;  3KE8 A;  3SZO A;  3NEI A;  3KEF A;  3KEL A;  2E8H A;  2DXW A;  2EGB A;  2DV3 A;  2E4N A;  2HUX A;  2PCK A;  4MV0 A;  2EL3 A;  3UV3 A;  3URK A;  2EK7 A;  2DV4 A;  2E15 A;  3KE9 A;  1CBF A; 
#chains in the Genus database with same CATH homology
 1VCE A;  2OWU A;  2E17 A;  3I4T A;  4H4D A;  3UV6 A;  2OWV A;  2OWK A;  2EH4 A;  3ZGN A;  2E16 A;  3ND1 A;  3UWM A;  2E0K A;  3T0G A;  3NUT A;  2EMR A;  2E08 A;  4MV5 A;  2BB3 A;  1WYZ A;  2E7R A;  4E16 A;  2P6D A;  2PCH A;  2DSH A;  4H4E A;  4MUX A;  2EK4 A;  2CBF A;  3KEM A;  2EJK A;  2P2X A;  2ZVC A;  3FFY A;  2E8S A;  1VA0 A;  3TIX B;  2YBQ A;  3UTD A;  2EHC A;  2E8Q A;  2PCI A;  3UTC A;  2ED5 A;  2E07 A;  3DNF A;  1PJT A;  1VHV A;  1VE2 A;  2ENI A;  2OWG A;  2EH2 A;  2EN5 A;  1PJQ A;  2DV7 A;  2EEQ A;  2PB6 A;  3KWP A;  1PJS A;  2YBO A;  3SZU A;  2PCA A;  2P6I A;  2EKA A;  2EJJ A;  3HH1 A;  2HUV A;  2DXV A;  1S4D A;  2EL0 A;  2HR8 A;  2HUT A;  2EL1 A;  2PCM A;  5HW4 A;  4N7B A;  4EB3 A;  2DXX A;  2E8R A;  2EGS A;  2KYY A;  2EL2 A;  2P6L A;  3NDC A;  4MUY A;  2HUQ A;  3FQ6 A;  2EH5 A;  2ZVB A;  3LMM A;  2EMU A;  2DV5 A;  2E0N A;  2P5F A;  2PB4 A;  2Z6R A;  2EHL A;  2EK3 A;  1V9A A;  2OWF A;  2EJZ A;  4H4C A;  2ED3 A;  3F7T A;  1WNG A;  2DSG A;  2PCG A;  2DEK A;  2P6K A;  2ELE A;  1WDE A;  2PB5 A;  3SZL A;  2E4R A;  2EGL A;  3UV7 A;  2DSI A;  2EK2 A;  2P5C A;  2QBU A;  2ELD A;  2NPN A;  2P9D A;  3T0F A;  3ZGL A;  3KE8 A;  3SZO A;  3NEI A;  3KEF A;  3KEL A;  2E8H A;  2DXW A;  2EGB A;  2DV3 A;  2E4N A;  2HUX A;  2PCK A;  4MV0 A;  2EL3 A;  3UV3 A;  3URK A;  2EK7 A;  2DV4 A;  2E15 A;  3KE9 A;  1CBF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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