2E4RA

Mutant i253m structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
265
structure length
265
Chain Sequence
b'MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEMAGAPREILRVNV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords diphthine synthase
publication title Mutant I253M structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Transferase
total genus 83
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2e4rA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2e4rA01
1VA0A 2EN5A 2EMUA 2DSHA 2EHCA 2P6DA 2P5CA 2P9DA 2EH5A 2PCIA 2ED5A 3NEIA 2PCGA 2EH2A 2EL3A 1WNGA 3FQ6A 2EH4A 2YBOA 4E16A 2E8SA 2E15A 2HUXA 3KWPA 2ZVBA 2ED3A 2P5FA 2E17A 2P6IA 2E4NA 2P2XA 2E07A 2EGBA 2EJJA 1CBFA 2E8HA 3FFYA 1VE2A 2YBQA 2DSIA 2OWUA 2P6LA 2HR8A 1WDEA 2E8QA 1S4DA 2ELDA 2EHLA 2DV4A 2E4RA 2ENIA 2E0NA 2EL1A 2PCHA 2DXVA 2BB3A 2P6KA 2ELEA 2DV5A 1PJSA 2EL0A 2ZVCA 3NDCA 1WYZA 1VHVA 2DV7A 2EK3A 2PB4A 2PCKA 2OWFA 2NPNA 2EK2A 2HUQA 1PJTA 3NUTA 2OWGA 2EEQA 2HUVA 2CBFA 1V9AA 2DSGA 2PCMA 5HW4A 2PB6A 2DXXA 2DV3A 2E08A 2EJKA 2DEKA 2EJZA 2Z6RA 2E7RA 3I4TA 2OWKA 2EL2A 2HUTA 2EK4A 2EKAA 1VCEA 2E16A 2EK7A 2OWVA 3ND1A 2EGLA 2EMRA 2PB5A 2EGSA 2QBUA 2E0KA 2PCAA 2DXWA 2E8RA 3HH1A 1PJQA
chains in the Genus database with same CATH superfamily
1VA0A 3UTCA 2EN5A 2EMUA 3KE8A 2DSHA 4H4CA 3TIXB 2EHCA 2P6DA 2P5CA 2P9DA 2EH5A 3T0GA 2PCIA 4EB3A 3DNFA 2ED5A 3UTDA 3NEIA 2PCGA 2EH2A 2EL3A 4MV0A 1WNGA 3FQ6A 2EH4A 2YBOA 4E16A 2E8SA 4MV5A 3KEFA 2E15A 2HUXA 3KWPA 2ZVBA 2ED3A 2P5FA 2E17A 2P6IA 2E4NA 2P2XA 2E07A 2EGBA 2EJJA 1CBFA 2E8HA 3FFYA 1VE2A 3SZOA 2YBQA 2DSIA 2OWUA 2P6LA 2HR8A 4MUXA 1WDEA 3SZLA 2E8QA 1S4DA 2ELDA 2EHLA 2DV4A 4H4DA 2E4RA 2ENIA 2E0NA 2EL1A 2PCHA 2DXVA 2BB3A 2P6KA 2ELEA 2DV5A 3UV3A 1PJSA 2EL0A 2ZVCA 3NDCA 4MUYA 4N7BA 1WYZA 3T0FA 1VHVA 2KYYA 3ZGLA 2DV7A 2EK3A 2PB4A 2PCKA 2OWFA 2NPNA 2EK2A 2HUQA 1PJTA 3UV7A 3KE9A 3NUTA 2OWGA 2EEQA 2HUVA 2CBFA 1V9AA 2DSGA 2PCMA 5HW4A 2PB6A 3URKA 2DXXA 2DV3A 2E08A 3F7TA 2EJKA 2DEKA 2EJZA 2Z6RA 2E7RA 3LMMA 3I4TA 3ZGNA 2OWKA 2EL2A 3KEMA 3SZUA 2HUTA 2EK4A 4H4EA 3UV6A 2EKAA 1VCEA 2E16A 2EK7A 2OWVA 3ND1A 2EGLA 2EMRA 2PB5A 3UWMA 2EGSA 2QBUA 2E0KA 3KELA 2PCAA 2DXWA 2E8RA 3HH1A 1PJQA
chains in the Genus database with same CATH topology
1VA0A 3UTCA 2EN5A 2EMUA 3KE8A 2DSHA 4H4CA 3TIXB 2EHCA 2P6DA 2P5CA 2P9DA 2EH5A 3T0GA 2PCIA 4EB3A 3DNFA 2ED5A 3UTDA 3NEIA 2PCGA 2EH2A 2EL3A 4MV0A 1WNGA 3FQ6A 2EH4A 2YBOA 4E16A 2E8SA 4MV5A 3KEFA 2E15A 2HUXA 3KWPA 2ZVBA 2ED3A 2P5FA 2E17A 2P6IA 2E4NA 2P2XA 2E07A 2EGBA 2EJJA 1CBFA 2E8HA 3FFYA 1VE2A 3SZOA 2YBQA 2DSIA 2OWUA 2P6LA 2HR8A 4MUXA 1WDEA 3SZLA 2E8QA 1S4DA 2ELDA 2EHLA 2DV4A 4H4DA 2E4RA 2ENIA 2E0NA 2EL1A 2PCHA 2DXVA 2BB3A 2P6KA 2ELEA 2DV5A 3UV3A 1PJSA 2EL0A 2ZVCA 3NDCA 4MUYA 4N7BA 1WYZA 3T0FA 1VHVA 2KYYA 3ZGLA 2DV7A 2EK3A 2PB4A 2PCKA 2OWFA 2NPNA 2EK2A 2HUQA 1PJTA 3UV7A 3KE9A 3NUTA 2OWGA 2EEQA 2HUVA 2CBFA 1V9AA 2DSGA 2PCMA 5HW4A 2PB6A 3URKA 2DXXA 2DV3A 2E08A 3F7TA 2EJKA 2DEKA 2EJZA 2Z6RA 2E7RA 3LMMA 3I4TA 3ZGNA 2OWKA 2EL2A 3KEMA 3SZUA 2HUTA 2EK4A 4H4EA 3UV6A 2EKAA 1VCEA 2E16A 2EK7A 2OWVA 3ND1A 2EGLA 2EMRA 2PB5A 3UWMA 2EGSA 2QBUA 2E0KA 3KELA 2PCAA 2DXWA 2E8RA 3HH1A 1PJQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VA0 A;  2EN5 A;  2EMU A;  2DSH A;  2EHC A;  2P6D A;  2P5C A;  2P9D A;  2EH5 A;  2PCI A;  2ED5 A;  3NEI A;  2PCG A;  2EH2 A;  2EL3 A;  1WNG A;  3FQ6 A;  2EH4 A;  2YBO A;  4E16 A;  2E8S A;  2E15 A;  2HUX A;  3KWP A;  2ZVB A;  2ED3 A;  2P5F A;  2E17 A;  2P6I A;  2E4N A;  2P2X A;  2E07 A;  2EGB A;  2EJJ A;  1CBF A;  2E8H A;  3FFY A;  1VE2 A;  2YBQ A;  2DSI A;  2OWU A;  2P6L A;  2HR8 A;  1WDE A;  2E8Q A;  1S4D A;  2ELD A;  2EHL A;  2DV4 A;  2E4R A;  2ENI A;  2E0N A;  2EL1 A;  2PCH A;  2DXV A;  2BB3 A;  2P6K A;  2ELE A;  2DV5 A;  1PJS A;  2EL0 A;  2ZVC A;  3NDC A;  1WYZ A;  1VHV A;  2DV7 A;  2EK3 A;  2PB4 A;  2PCK A;  2OWF A;  2NPN A;  2EK2 A;  2HUQ A;  1PJT A;  3NUT A;  2OWG A;  2EEQ A;  2HUV A;  2CBF A;  1V9A A;  2DSG A;  2PCM A;  5HW4 A;  2PB6 A;  2DXX A;  2DV3 A;  2E08 A;  2EJK A;  2DEK A;  2EJZ A;  2Z6R A;  2E7R A;  3I4T A;  2OWK A;  2EL2 A;  2HUT A;  2EK4 A;  2EKA A;  1VCE A;  2E16 A;  2EK7 A;  2OWV A;  3ND1 A;  2EGL A;  2EMR A;  2PB5 A;  2EGS A;  2QBU A;  2E0K A;  2PCA A;  2DXW A;  2E8R A;  3HH1 A;  1PJQ A; 
#chains in the Genus database with same CATH topology
 1VA0 A;  3UTC A;  2EN5 A;  2EMU A;  3KE8 A;  2DSH A;  4H4C A;  3TIX B;  2EHC A;  2P6D A;  2P5C A;  2P9D A;  2EH5 A;  3T0G A;  2PCI A;  4EB3 A;  3DNF A;  2ED5 A;  3UTD A;  3NEI A;  2PCG A;  2EH2 A;  2EL3 A;  4MV0 A;  1WNG A;  3FQ6 A;  2EH4 A;  2YBO A;  4E16 A;  2E8S A;  4MV5 A;  3KEF A;  2E15 A;  2HUX A;  3KWP A;  2ZVB A;  2ED3 A;  2P5F A;  2E17 A;  2P6I A;  2E4N A;  2P2X A;  2E07 A;  2EGB A;  2EJJ A;  1CBF A;  2E8H A;  3FFY A;  1VE2 A;  3SZO A;  2YBQ A;  2DSI A;  2OWU A;  2P6L A;  2HR8 A;  4MUX A;  1WDE A;  3SZL A;  2E8Q A;  1S4D A;  2ELD A;  2EHL A;  2DV4 A;  4H4D A;  2E4R A;  2ENI A;  2E0N A;  2EL1 A;  2PCH A;  2DXV A;  2BB3 A;  2P6K A;  2ELE A;  2DV5 A;  3UV3 A;  1PJS A;  2EL0 A;  2ZVC A;  3NDC A;  4MUY A;  4N7B A;  1WYZ A;  3T0F A;  1VHV A;  2KYY A;  3ZGL A;  2DV7 A;  2EK3 A;  2PB4 A;  2PCK A;  2OWF A;  2NPN A;  2EK2 A;  2HUQ A;  1PJT A;  3UV7 A;  3KE9 A;  3NUT A;  2OWG A;  2EEQ A;  2HUV A;  2CBF A;  1V9A A;  2DSG A;  2PCM A;  5HW4 A;  2PB6 A;  3URK A;  2DXX A;  2DV3 A;  2E08 A;  3F7T A;  2EJK A;  2DEK A;  2EJZ A;  2Z6R A;  2E7R A;  3LMM A;  3I4T A;  3ZGN A;  2OWK A;  2EL2 A;  3KEM A;  3SZU A;  2HUT A;  2EK4 A;  4H4E A;  3UV6 A;  2EKA A;  1VCE A;  2E16 A;  2EK7 A;  2OWV A;  3ND1 A;  2EGL A;  2EMR A;  2PB5 A;  3UWM A;  2EGS A;  2QBU A;  2E0K A;  3KEL A;  2PCA A;  2DXW A;  2E8R A;  3HH1 A;  1PJQ A; 
#chains in the Genus database with same CATH homology
 1VA0 A;  3UTC A;  2EN5 A;  2EMU A;  3KE8 A;  2DSH A;  4H4C A;  3TIX B;  2EHC A;  2P6D A;  2P5C A;  2P9D A;  2EH5 A;  3T0G A;  2PCI A;  4EB3 A;  3DNF A;  2ED5 A;  3UTD A;  3NEI A;  2PCG A;  2EH2 A;  2EL3 A;  4MV0 A;  1WNG A;  3FQ6 A;  2EH4 A;  2YBO A;  4E16 A;  2E8S A;  4MV5 A;  3KEF A;  2E15 A;  2HUX A;  3KWP A;  2ZVB A;  2ED3 A;  2P5F A;  2E17 A;  2P6I A;  2E4N A;  2P2X A;  2E07 A;  2EGB A;  2EJJ A;  1CBF A;  2E8H A;  3FFY A;  1VE2 A;  3SZO A;  2YBQ A;  2DSI A;  2OWU A;  2P6L A;  2HR8 A;  4MUX A;  1WDE A;  3SZL A;  2E8Q A;  1S4D A;  2ELD A;  2EHL A;  2DV4 A;  4H4D A;  2E4R A;  2ENI A;  2E0N A;  2EL1 A;  2PCH A;  2DXV A;  2BB3 A;  2P6K A;  2ELE A;  2DV5 A;  3UV3 A;  1PJS A;  2EL0 A;  2ZVC A;  3NDC A;  4MUY A;  4N7B A;  1WYZ A;  3T0F A;  1VHV A;  2KYY A;  3ZGL A;  2DV7 A;  2EK3 A;  2PB4 A;  2PCK A;  2OWF A;  2NPN A;  2EK2 A;  2HUQ A;  1PJT A;  3UV7 A;  3KE9 A;  3NUT A;  2OWG A;  2EEQ A;  2HUV A;  2CBF A;  1V9A A;  2DSG A;  2PCM A;  5HW4 A;  2PB6 A;  3URK A;  2DXX A;  2DV3 A;  2E08 A;  3F7T A;  2EJK A;  2DEK A;  2EJZ A;  2Z6R A;  2E7R A;  3LMM A;  3I4T A;  3ZGN A;  2OWK A;  2EL2 A;  3KEM A;  3SZU A;  2HUT A;  2EK4 A;  4H4E A;  3UV6 A;  2EKA A;  1VCE A;  2E16 A;  2EK7 A;  2OWV A;  3ND1 A;  2EGL A;  2EMR A;  2PB5 A;  3UWM A;  2EGS A;  2QBU A;  2E0K A;  3KEL A;  2PCA A;  2DXW A;  2E8R A;  3HH1 A;  1PJQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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