2E07 | Genus

Total Genus 85

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	85
sequence length	265
structure length	265
Chain Sequence	MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENEVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__968869396668651__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__968869396668651__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/2E07/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__968869396668651__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"968869396668651","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/2E07/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__968869396668651__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Pyrococcus horikoshii
publication title	Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 rcsb
molecule keywords	Probable diphthine synthase
total genus	85
structure length	265
sequence length	265
chains with identical sequence	B
ec nomenclature	ec 2.1.1.98: Diphthine synthase.
pdb deposition date	2006-10-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00590	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.950.10	Alpha Beta	2-Layer Sandwich	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	2e07A02
3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase; domain 1	Cobalt-precorrin-4 Transmethylase; Domain 1	2e07A01

2E0NA 2PCMA 2DXVA 1V9AA 2DEKA 3KWPA 2EJJA 2EK7A 2BB3A 2PB6A 2ZVBA 3NUTA 2EJKA 2P6KA 1PJSA 2ZVCA 2ELDA 3FQ6A 2E4NA 2E7RA 2EH2A 2HUXA 1PJTA 2DV4A 1VA0A 2CBFA 1VCEA 2DV7A 2HUVA 2EGLA 2PCGA 2E17A 2EL1A 2ED5A 2OWKA 2YBOA 1VHVA 3HH1A 1S4DA 2PB5A 2DV3A 2EN5A 2Z6RA 2YBQA 2HUQA 2DSIA 2E8RA 2P6DA 2E8HA 3I4TA 2EK4A 2EL0A 3NDCA 2PCAA 2EMUA 2ENIA 2P6LA 2EH5A 2E8QA 2EGBA 2EHLA 2P6IA 1WYZA 2E8SA 2EH4A 2E08A 2OWGA 2E16A 3ND1A 2EL2A 2E4RA 2NPNA 1PJQA 2P5CA 2PCHA 2P5FA 2HUTA 2ED3A 2EEQA 3FFYA 2QBUA 2EK2A 2EK3A 2PCIA 2E07A 2EJZA 2EL3A 1WDEA 1VE2A 2EGSA 2EMRA 2OWVA 2ELEA 2P9DA 2DXWA 5HW4A 2PB4A 1CBFA 2HR8A 2OWFA 2OWUA 2E0KA 2DXXA 2E15A 3NEIA 2P2XA 1WNGA 4E16A 2DSGA 2EHCA 2DSHA 2PCKA 2DV5A 2EKAA
chains in the Genus database with same CATH superfamily

2E0NA 2PCMA 2DXVA 1V9AA 2DEKA 3DNFA 3KWPA 2EJJA 2EK7A 2BB3A 2PB6A 4H4CA 2ZVBA 3KEFA 3NUTA 2EJKA 2P6KA 1PJSA 2ZVCA 2ELDA 3ZGLA 3UV6A 3FQ6A 2E4NA 2E7RA 2EH2A 2HUXA 1PJTA 2DV4A 4MV5A 1VA0A 3KE9A 3KE8A 2CBFA 3KEMA 1VCEA 2DV7A 2HUVA 2EGLA 3TIXB 2PCGA 3KELA 2E17A 2EL1A 2ED5A 2OWKA 2YBOA 1VHVA 3HH1A 3UWMA 1S4DA 2PB5A 2DV3A 2EN5A 2Z6RA 4MV0A 4MUYA 2YBQA 2HUQA 2DSIA 2E8RA 2P6DA 3SZLA 2E8HA 3I4TA 3SZOA 2EK4A 2EL0A 3NDCA 2PCAA 2EMUA 2ENIA 2P6LA 2EH5A 2E8QA 2EGBA 2EHLA 2P6IA 1WYZA 3ZGNA 2E8SA 2EH4A 2E08A 2OWGA 3T0FA 3T0GA 2E16A 3LMMA 3ND1A 3SZUA 2EL2A 2E4RA 4H4EA 4MUXA 2NPNA 1PJQA 2P5CA 3F7TA 2PCHA 4H4DA 2P5FA 3UV3A 2HUTA 2ED3A 2EEQA 3URKA 3FFYA 2QBUA 2EK2A 2EK3A 2PCIA 2E07A 2EJZA 2EL3A 1WDEA 1VE2A 2EGSA 2EMRA 3UV7A 2KYYA 2OWVA 2ELEA 2P9DA 2DXWA 5HW4A 2PB4A 1CBFA 2HR8A 2OWFA 2OWUA 2E0KA 2DXXA 3UTCA 2E15A 3NEIA 2P2XA 1WNGA 4E16A 2DSGA 2EHCA 2DSHA 4N7BA 2PCKA 4EB3A 3UTDA 2DV5A 2EKAA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2E0N A;  2PCM A;  2DXV A;  1V9A A;  2DEK A;  3KWP A;  2EJJ A;  2EK7 A;  2BB3 A;  2PB6 A;  2ZVB A;  3NUT A;  2EJK A;  2P6K A;  1PJS A;  2ZVC A;  2ELD A;  3FQ6 A;  2E4N A;  2E7R A;  2EH2 A;  2HUX A;  1PJT A;  2DV4 A;  1VA0 A;  2CBF A;  1VCE A;  2DV7 A;  2HUV A;  2EGL A;  2PCG A;  2E17 A;  2EL1 A;  2ED5 A;  2OWK A;  2YBO A;  1VHV A;  3HH1 A;  1S4D A;  2PB5 A;  2DV3 A;  2EN5 A;  2Z6R A;  2YBQ A;  2HUQ A;  2DSI A;  2E8R A;  2P6D A;  2E8H A;  3I4T A;  2EK4 A;  2EL0 A;  3NDC A;  2PCA A;  2EMU A;  2ENI A;  2P6L A;  2EH5 A;  2E8Q A;  2EGB A;  2EHL A;  2P6I A;  1WYZ A;  2E8S A;  2EH4 A;  2E08 A;  2OWG A;  2E16 A;  3ND1 A;  2EL2 A;  2E4R A;  2NPN A;  1PJQ A;  2P5C A;  2PCH A;  2P5F A;  2HUT A;  2ED3 A;  2EEQ A;  3FFY A;  2QBU A;  2EK2 A;  2EK3 A;  2PCI A;  2E07 A;  2EJZ A;  2EL3 A;  1WDE A;  1VE2 A;  2EGS A;  2EMR A;  2OWV A;  2ELE A;  2P9D A;  2DXW A;  5HW4 A;  2PB4 A;  1CBF A;  2HR8 A;  2OWF A;  2OWU A;  2E0K A;  2DXX A;  2E15 A;  3NEI A;  2P2X A;  1WNG A;  4E16 A;  2DSG A;  2EHC A;  2DSH A;  2PCK A;  2DV5 A;  2EKA A; 
#chains in the Genus database with same CATH topology
 2E0N A;  2PCM A;  2DXV A;  1V9A A;  2DEK A;  3DNF A;  3KWP A;  2EJJ A;  2EK7 A;  2BB3 A;  2PB6 A;  4H4C A;  2ZVB A;  3KEF A;  3NUT A;  2EJK A;  2P6K A;  1PJS A;  2ZVC A;  2ELD A;  3ZGL A;  3UV6 A;  3FQ6 A;  2E4N A;  2E7R A;  2EH2 A;  2HUX A;  1PJT A;  2DV4 A;  4MV5 A;  1VA0 A;  3KE9 A;  3KE8 A;  2CBF A;  3KEM A;  1VCE A;  2DV7 A;  2HUV A;  2EGL A;  3TIX B;  2PCG A;  3KEL A;  2E17 A;  2EL1 A;  2ED5 A;  2OWK A;  2YBO A;  1VHV A;  3HH1 A;  3UWM A;  1S4D A;  2PB5 A;  2DV3 A;  2EN5 A;  2Z6R A;  4MV0 A;  4MUY A;  2YBQ A;  2HUQ A;  2DSI A;  2E8R A;  2P6D A;  3SZL A;  2E8H A;  3I4T A;  3SZO A;  2EK4 A;  2EL0 A;  3NDC A;  2PCA A;  2EMU A;  2ENI A;  2P6L A;  2EH5 A;  2E8Q A;  2EGB A;  2EHL A;  2P6I A;  1WYZ A;  3ZGN A;  2E8S A;  2EH4 A;  2E08 A;  2OWG A;  3T0F A;  3T0G A;  2E16 A;  3LMM A;  3ND1 A;  3SZU A;  2EL2 A;  2E4R A;  4H4E A;  4MUX A;  2NPN A;  1PJQ A;  2P5C A;  3F7T A;  2PCH A;  4H4D A;  2P5F A;  3UV3 A;  2HUT A;  2ED3 A;  2EEQ A;  3URK A;  3FFY A;  2QBU A;  2EK2 A;  2EK3 A;  2PCI A;  2E07 A;  2EJZ A;  2EL3 A;  1WDE A;  1VE2 A;  2EGS A;  2EMR A;  3UV7 A;  2KYY A;  2OWV A;  2ELE A;  2P9D A;  2DXW A;  5HW4 A;  2PB4 A;  1CBF A;  2HR8 A;  2OWF A;  2OWU A;  2E0K A;  2DXX A;  3UTC A;  2E15 A;  3NEI A;  2P2X A;  1WNG A;  4E16 A;  2DSG A;  2EHC A;  2DSH A;  4N7B A;  2PCK A;  4EB3 A;  3UTD A;  2DV5 A;  2EKA A; 
#chains in the Genus database with same CATH homology
 2E0N A;  2PCM A;  2DXV A;  1V9A A;  2DEK A;  3DNF A;  3KWP A;  2EJJ A;  2EK7 A;  2BB3 A;  2PB6 A;  4H4C A;  2ZVB A;  3KEF A;  3NUT A;  2EJK A;  2P6K A;  1PJS A;  2ZVC A;  2ELD A;  3ZGL A;  3UV6 A;  3FQ6 A;  2E4N A;  2E7R A;  2EH2 A;  2HUX A;  1PJT A;  2DV4 A;  4MV5 A;  1VA0 A;  3KE9 A;  3KE8 A;  2CBF A;  3KEM A;  1VCE A;  2DV7 A;  2HUV A;  2EGL A;  3TIX B;  2PCG A;  3KEL A;  2E17 A;  2EL1 A;  2ED5 A;  2OWK A;  2YBO A;  1VHV A;  3HH1 A;  3UWM A;  1S4D A;  2PB5 A;  2DV3 A;  2EN5 A;  2Z6R A;  4MV0 A;  4MUY A;  2YBQ A;  2HUQ A;  2DSI A;  2E8R A;  2P6D A;  3SZL A;  2E8H A;  3I4T A;  3SZO A;  2EK4 A;  2EL0 A;  3NDC A;  2PCA A;  2EMU A;  2ENI A;  2P6L A;  2EH5 A;  2E8Q A;  2EGB A;  2EHL A;  2P6I A;  1WYZ A;  3ZGN A;  2E8S A;  2EH4 A;  2E08 A;  2OWG A;  3T0F A;  3T0G A;  2E16 A;  3LMM A;  3ND1 A;  3SZU A;  2EL2 A;  2E4R A;  4H4E A;  4MUX A;  2NPN A;  1PJQ A;  2P5C A;  3F7T A;  2PCH A;  4H4D A;  2P5F A;  3UV3 A;  2HUT A;  2ED3 A;  2EEQ A;  3URK A;  3FFY A;  2QBU A;  2EK2 A;  2EK3 A;  2PCI A;  2E07 A;  2EJZ A;  2EL3 A;  1WDE A;  1VE2 A;  2EGS A;  2EMR A;  3UV7 A;  2KYY A;  2OWV A;  2ELE A;  2P9D A;  2DXW A;  5HW4 A;  2PB4 A;  1CBF A;  2HR8 A;  2OWF A;  2OWU A;  2E0K A;  2DXX A;  3UTC A;  2E15 A;  3NEI A;  2P2X A;  1WNG A;  4E16 A;  2DSG A;  2EHC A;  2DSH A;  4N7B A;  2PCK A;  4EB3 A;  3UTD A;  2DV5 A;  2EKA A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

2E07A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations