2E8H | Genus

Total Genus 83

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	83
sequence length	265
structure length	265
Chain Sequence	MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLMFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Pyrococcus horikoshii
publication title	Crystal structure of PH0725 from Pyrococcus horikoshii OT3 rcsb
molecule keywords	Probable diphthine synthase
total genus	83
structure length	265
sequence length	265
chains with identical sequence	B
ec nomenclature	ec 2.1.1.98: Diphthine synthase.
pdb deposition date	2007-01-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00590	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.950.10	Alpha Beta	2-Layer Sandwich	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	2e8hA02
3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase; domain 1	Cobalt-precorrin-4 Transmethylase; Domain 1	2e8hA01

2QBUA 2DSHA 2EGLA 2P5CA 2DV5A 2PB6A 2EL2A 2PCAA 2DV3A 2HR8A 2HUQA 2DSIA 2E16A 2EMRA 1PJSA 2PB5A 2E8SA 2E8HA 2EH2A 2OWGA 2PCIA 3ND1A 2E8RA 2DXWA 2EL3A 3I4TA 5HW4A 2HUTA 2EJKA 2EGSA 2NPNA 2HUXA 2BB3A 2PCMA 2EKAA 2OWKA 2EN5A 2YBOA 2E8QA 3FQ6A 1VA0A 2EHCA 2PCHA 3HH1A 1WNGA 2DSGA 2EL1A 1PJTA 2ED3A 2CBFA 2DV4A 2DXVA 1CBFA 2EGBA 2E7RA 3NUTA 2EJZA 2EH4A 2EK2A 2ENIA 2DV7A 1VE2A 2E4NA 1VCEA 4E16A 2PB4A 2EK3A 2ED5A 2E17A 2EH5A 2ZVCA 3FFYA 1VHVA 1WYZA 2OWFA 3KWPA 1WDEA 1PJQA 2EK4A 1S4DA 2EHLA 2P9DA 2E07A 2E0KA 2EK7A 2Z6RA 1V9AA 2YBQA 2EEQA 2ELEA 2OWUA 2ELDA 2HUVA 2PCGA 2E4RA 2EL0A 2E08A 2P2XA 2P6LA 2E15A 2PCKA 3NEIA 2DXXA 2P6KA 2E0NA 2EMUA 2P6DA 2OWVA 2EJJA 2P6IA 2DEKA 2ZVBA 2P5FA 3NDCA
chains in the Genus database with same CATH superfamily

2QBUA 2DSHA 2EGLA 2P5CA 2DV5A 2PB6A 2EL2A 2PCAA 2DV3A 2HR8A 2HUQA 4MV0A 2DSIA 4H4EA 3UV3A 2E16A 4MUXA 2EMRA 1PJSA 2KYYA 2PB5A 3T0FA 2E8SA 3F7TA 2E8HA 3SZLA 2EH2A 3DNFA 2OWGA 2PCIA 3ND1A 2E8RA 2DXWA 2EL3A 3URKA 3KE9A 3I4TA 5HW4A 2HUTA 3ZGLA 2EJKA 2EGSA 2NPNA 2HUXA 2BB3A 2PCMA 2EKAA 2OWKA 2EN5A 2YBOA 2E8QA 3UTDA 3FQ6A 3KE8A 3KEFA 3T0GA 1VA0A 4H4DA 2EHCA 2PCHA 3HH1A 1WNGA 3KELA 4N7BA 2DSGA 2EL1A 1PJTA 2ED3A 2CBFA 2DV4A 4H4CA 2DXVA 1CBFA 2EGBA 2E7RA 3NUTA 3UWMA 2EJZA 2EH4A 2EK2A 2ENIA 2DV7A 1VE2A 2E4NA 1VCEA 4E16A 2PB4A 2EK3A 2ED5A 2E17A 2EH5A 2ZVCA 3FFYA 1VHVA 4MV5A 1WYZA 3ZGNA 3KEMA 2OWFA 3KWPA 1WDEA 1PJQA 4EB3A 2EK4A 1S4DA 3UV6A 2EHLA 2P9DA 3UV7A 3SZUA 2E07A 2E0KA 2EK7A 2Z6RA 1V9AA 2YBQA 3UTCA 2EEQA 2ELEA 2OWUA 3LMMA 3SZOA 4MUYA 2ELDA 2HUVA 2PCGA 2E4RA 2EL0A 2E08A 2P2XA 2P6LA 2E15A 2PCKA 3NEIA 2DXXA 2P6KA 2E0NA 2EMUA 2P6DA 2OWVA 2EJJA 2P6IA 2DEKA 2ZVBA 2P5FA 3TIXB 3NDCA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2QBU A;  2DSH A;  2EGL A;  2P5C A;  2DV5 A;  2PB6 A;  2EL2 A;  2PCA A;  2DV3 A;  2HR8 A;  2HUQ A;  2DSI A;  2E16 A;  2EMR A;  1PJS A;  2PB5 A;  2E8S A;  2E8H A;  2EH2 A;  2OWG A;  2PCI A;  3ND1 A;  2E8R A;  2DXW A;  2EL3 A;  3I4T A;  5HW4 A;  2HUT A;  2EJK A;  2EGS A;  2NPN A;  2HUX A;  2BB3 A;  2PCM A;  2EKA A;  2OWK A;  2EN5 A;  2YBO A;  2E8Q A;  3FQ6 A;  1VA0 A;  2EHC A;  2PCH A;  3HH1 A;  1WNG A;  2DSG A;  2EL1 A;  1PJT A;  2ED3 A;  2CBF A;  2DV4 A;  2DXV A;  1CBF A;  2EGB A;  2E7R A;  3NUT A;  2EJZ A;  2EH4 A;  2EK2 A;  2ENI A;  2DV7 A;  1VE2 A;  2E4N A;  1VCE A;  4E16 A;  2PB4 A;  2EK3 A;  2ED5 A;  2E17 A;  2EH5 A;  2ZVC A;  3FFY A;  1VHV A;  1WYZ A;  2OWF A;  3KWP A;  1WDE A;  1PJQ A;  2EK4 A;  1S4D A;  2EHL A;  2P9D A;  2E07 A;  2E0K A;  2EK7 A;  2Z6R A;  1V9A A;  2YBQ A;  2EEQ A;  2ELE A;  2OWU A;  2ELD A;  2HUV A;  2PCG A;  2E4R A;  2EL0 A;  2E08 A;  2P2X A;  2P6L A;  2E15 A;  2PCK A;  3NEI A;  2DXX A;  2P6K A;  2E0N A;  2EMU A;  2P6D A;  2OWV A;  2EJJ A;  2P6I A;  2DEK A;  2ZVB A;  2P5F A;  3NDC A; 
#chains in the Genus database with same CATH topology
 2QBU A;  2DSH A;  2EGL A;  2P5C A;  2DV5 A;  2PB6 A;  2EL2 A;  2PCA A;  2DV3 A;  2HR8 A;  2HUQ A;  4MV0 A;  2DSI A;  4H4E A;  3UV3 A;  2E16 A;  4MUX A;  2EMR A;  1PJS A;  2KYY A;  2PB5 A;  3T0F A;  2E8S A;  3F7T A;  2E8H A;  3SZL A;  2EH2 A;  3DNF A;  2OWG A;  2PCI A;  3ND1 A;  2E8R A;  2DXW A;  2EL3 A;  3URK A;  3KE9 A;  3I4T A;  5HW4 A;  2HUT A;  3ZGL A;  2EJK A;  2EGS A;  2NPN A;  2HUX A;  2BB3 A;  2PCM A;  2EKA A;  2OWK A;  2EN5 A;  2YBO A;  2E8Q A;  3UTD A;  3FQ6 A;  3KE8 A;  3KEF A;  3T0G A;  1VA0 A;  4H4D A;  2EHC A;  2PCH A;  3HH1 A;  1WNG A;  3KEL A;  4N7B A;  2DSG A;  2EL1 A;  1PJT A;  2ED3 A;  2CBF A;  2DV4 A;  4H4C A;  2DXV A;  1CBF A;  2EGB A;  2E7R A;  3NUT A;  3UWM A;  2EJZ A;  2EH4 A;  2EK2 A;  2ENI A;  2DV7 A;  1VE2 A;  2E4N A;  1VCE A;  4E16 A;  2PB4 A;  2EK3 A;  2ED5 A;  2E17 A;  2EH5 A;  2ZVC A;  3FFY A;  1VHV A;  4MV5 A;  1WYZ A;  3ZGN A;  3KEM A;  2OWF A;  3KWP A;  1WDE A;  1PJQ A;  4EB3 A;  2EK4 A;  1S4D A;  3UV6 A;  2EHL A;  2P9D A;  3UV7 A;  3SZU A;  2E07 A;  2E0K A;  2EK7 A;  2Z6R A;  1V9A A;  2YBQ A;  3UTC A;  2EEQ A;  2ELE A;  2OWU A;  3LMM A;  3SZO A;  4MUY A;  2ELD A;  2HUV A;  2PCG A;  2E4R A;  2EL0 A;  2E08 A;  2P2X A;  2P6L A;  2E15 A;  2PCK A;  3NEI A;  2DXX A;  2P6K A;  2E0N A;  2EMU A;  2P6D A;  2OWV A;  2EJJ A;  2P6I A;  2DEK A;  2ZVB A;  2P5F A;  3TIX B;  3NDC A; 
#chains in the Genus database with same CATH homology
 2QBU A;  2DSH A;  2EGL A;  2P5C A;  2DV5 A;  2PB6 A;  2EL2 A;  2PCA A;  2DV3 A;  2HR8 A;  2HUQ A;  4MV0 A;  2DSI A;  4H4E A;  3UV3 A;  2E16 A;  4MUX A;  2EMR A;  1PJS A;  2KYY A;  2PB5 A;  3T0F A;  2E8S A;  3F7T A;  2E8H A;  3SZL A;  2EH2 A;  3DNF A;  2OWG A;  2PCI A;  3ND1 A;  2E8R A;  2DXW A;  2EL3 A;  3URK A;  3KE9 A;  3I4T A;  5HW4 A;  2HUT A;  3ZGL A;  2EJK A;  2EGS A;  2NPN A;  2HUX A;  2BB3 A;  2PCM A;  2EKA A;  2OWK A;  2EN5 A;  2YBO A;  2E8Q A;  3UTD A;  3FQ6 A;  3KE8 A;  3KEF A;  3T0G A;  1VA0 A;  4H4D A;  2EHC A;  2PCH A;  3HH1 A;  1WNG A;  3KEL A;  4N7B A;  2DSG A;  2EL1 A;  1PJT A;  2ED3 A;  2CBF A;  2DV4 A;  4H4C A;  2DXV A;  1CBF A;  2EGB A;  2E7R A;  3NUT A;  3UWM A;  2EJZ A;  2EH4 A;  2EK2 A;  2ENI A;  2DV7 A;  1VE2 A;  2E4N A;  1VCE A;  4E16 A;  2PB4 A;  2EK3 A;  2ED5 A;  2E17 A;  2EH5 A;  2ZVC A;  3FFY A;  1VHV A;  4MV5 A;  1WYZ A;  3ZGN A;  3KEM A;  2OWF A;  3KWP A;  1WDE A;  1PJQ A;  4EB3 A;  2EK4 A;  1S4D A;  3UV6 A;  2EHL A;  2P9D A;  3UV7 A;  3SZU A;  2E07 A;  2E0K A;  2EK7 A;  2Z6R A;  1V9A A;  2YBQ A;  3UTC A;  2EEQ A;  2ELE A;  2OWU A;  3LMM A;  3SZO A;  4MUY A;  2ELD A;  2HUV A;  2PCG A;  2E4R A;  2EL0 A;  2E08 A;  2P2X A;  2P6L A;  2E15 A;  2PCK A;  3NEI A;  2DXX A;  2P6K A;  2E0N A;  2EMU A;  2P6D A;  2OWV A;  2EJJ A;  2P6I A;  2DEK A;  2ZVB A;  2P5F A;  3TIX B;  3NDC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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2E8HA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations