2EHL | Genus

Total Genus 86

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	86
sequence length	265
structure length	265
Chain Sequence	MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPRSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Pyrococcus horikoshii
publication title	Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 rcsb
molecule keywords	diphthine synthase
total genus	86
structure length	265
sequence length	265
chains with identical sequence	B
ec nomenclature	ec 2.1.1.98: Diphthine synthase.
pdb deposition date	2007-03-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00590	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.950.10	Alpha Beta	2-Layer Sandwich	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	2ehlA02
3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase; domain 1	Cobalt-precorrin-4 Transmethylase; Domain 1	2ehlA01

2CBFA 3NDCA 2DV3A 2HUVA 2ED5A 2PCIA 2HUTA 2DEKA 2E4NA 3KWPA 2EHLA 2P5CA 1WNGA 2OWGA 2NPNA 2EKAA 3FFYA 2DSHA 2EL2A 1WYZA 2PB6A 2OWKA 2E17A 2Z6RA 2QBUA 2DXXA 3FQ6A 2DV4A 2PCKA 2HUXA 1S4DA 2YBOA 2EK7A 2E0NA 2EL3A 2HUQA 3NUTA 2PCHA 2P6LA 2E8RA 2EK3A 1WDEA 1PJTA 2EMRA 2P6KA 3HH1A 2EH4A 2EL0A 2EJJA 3ND1A 1VA0A 2E07A 2DSIA 3NEIA 2E16A 2OWFA 1PJQA 2EJZA 2E08A 2E8HA 2E0KA 2EEQA 2EH2A 2EK2A 2EH5A 2OWUA 2P6IA 2EGLA 2DSGA 2EMUA 1VE2A 1VCEA 2P6DA 1PJSA 2EL1A 5HW4A 2PCMA 2DXWA 2E4RA 2BB3A 2EN5A 2EGSA 2ELDA 2PB4A 1VHVA 2HR8A 2EJKA 2P9DA 2EGBA 2E7RA 2OWVA 2ZVBA 4E16A 2EHCA 2P5FA 2PCAA 2ELEA 2E15A 2P2XA 2EK4A 2ZVCA 3I4TA 1CBFA 1V9AA 2YBQA 2DV7A 2DXVA 2PB5A 2E8QA 2E8SA 2DV5A 2ED3A 2PCGA 2ENIA
chains in the Genus database with same CATH superfamily

2CBFA 3NDCA 4H4CA 2DV3A 3ZGNA 2HUVA 2ED5A 2PCIA 2HUTA 2DEKA 3SZLA 2E4NA 3KWPA 2EHLA 3T0FA 3SZOA 2P5CA 1WNGA 3TIXB 2OWGA 2NPNA 2EKAA 3FFYA 2DSHA 3UV6A 2EL2A 1WYZA 2PB6A 4EB3A 2OWKA 3KE8A 2E17A 2Z6RA 2QBUA 2DXXA 3FQ6A 2DV4A 2PCKA 2HUXA 1S4DA 2YBOA 2EK7A 2E0NA 3UV3A 2EL3A 2HUQA 3NUTA 2PCHA 2P6LA 2E8RA 2EK3A 4MUYA 3KEFA 1WDEA 1PJTA 2EMRA 2P6KA 3ZGLA 3HH1A 3LMMA 2EH4A 3UV7A 2EL0A 2EJJA 3ND1A 1VA0A 2E07A 2DSIA 3NEIA 2E16A 2OWFA 1PJQA 2EJZA 2E08A 2E8HA 2E0KA 2EEQA 2EH2A 3DNFA 2EK2A 2EH5A 2OWUA 2P6IA 3KE9A 2EGLA 2DSGA 3T0GA 3F7TA 3KEMA 2EMUA 1VE2A 1VCEA 3KELA 2P6DA 3UWMA 1PJSA 2EL1A 5HW4A 2PCMA 2DXWA 2E4RA 2BB3A 3URKA 4H4EA 3UTCA 4N7BA 2EN5A 2EGSA 2ELDA 2PB4A 1VHVA 2HR8A 2EJKA 4MUXA 2P9DA 2EGBA 2E7RA 2OWVA 2ZVBA 4MV5A 4E16A 2EHCA 2P5FA 2PCAA 2ELEA 2E15A 2P2XA 2EK4A 2ZVCA 3I4TA 4MV0A 1CBFA 1V9AA 2YBQA 2DV7A 2DXVA 4H4DA 3SZUA 2PB5A 2E8QA 2E8SA 2DV5A 2KYYA 2ED3A 3UTDA 2PCGA 2ENIA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2CBF A;  3NDC A;  2DV3 A;  2HUV A;  2ED5 A;  2PCI A;  2HUT A;  2DEK A;  2E4N A;  3KWP A;  2EHL A;  2P5C A;  1WNG A;  2OWG A;  2NPN A;  2EKA A;  3FFY A;  2DSH A;  2EL2 A;  1WYZ A;  2PB6 A;  2OWK A;  2E17 A;  2Z6R A;  2QBU A;  2DXX A;  3FQ6 A;  2DV4 A;  2PCK A;  2HUX A;  1S4D A;  2YBO A;  2EK7 A;  2E0N A;  2EL3 A;  2HUQ A;  3NUT A;  2PCH A;  2P6L A;  2E8R A;  2EK3 A;  1WDE A;  1PJT A;  2EMR A;  2P6K A;  3HH1 A;  2EH4 A;  2EL0 A;  2EJJ A;  3ND1 A;  1VA0 A;  2E07 A;  2DSI A;  3NEI A;  2E16 A;  2OWF A;  1PJQ A;  2EJZ A;  2E08 A;  2E8H A;  2E0K A;  2EEQ A;  2EH2 A;  2EK2 A;  2EH5 A;  2OWU A;  2P6I A;  2EGL A;  2DSG A;  2EMU A;  1VE2 A;  1VCE A;  2P6D A;  1PJS A;  2EL1 A;  5HW4 A;  2PCM A;  2DXW A;  2E4R A;  2BB3 A;  2EN5 A;  2EGS A;  2ELD A;  2PB4 A;  1VHV A;  2HR8 A;  2EJK A;  2P9D A;  2EGB A;  2E7R A;  2OWV A;  2ZVB A;  4E16 A;  2EHC A;  2P5F A;  2PCA A;  2ELE A;  2E15 A;  2P2X A;  2EK4 A;  2ZVC A;  3I4T A;  1CBF A;  1V9A A;  2YBQ A;  2DV7 A;  2DXV A;  2PB5 A;  2E8Q A;  2E8S A;  2DV5 A;  2ED3 A;  2PCG A;  2ENI A; 
#chains in the Genus database with same CATH topology
 2CBF A;  3NDC A;  4H4C A;  2DV3 A;  3ZGN A;  2HUV A;  2ED5 A;  2PCI A;  2HUT A;  2DEK A;  3SZL A;  2E4N A;  3KWP A;  2EHL A;  3T0F A;  3SZO A;  2P5C A;  1WNG A;  3TIX B;  2OWG A;  2NPN A;  2EKA A;  3FFY A;  2DSH A;  3UV6 A;  2EL2 A;  1WYZ A;  2PB6 A;  4EB3 A;  2OWK A;  3KE8 A;  2E17 A;  2Z6R A;  2QBU A;  2DXX A;  3FQ6 A;  2DV4 A;  2PCK A;  2HUX A;  1S4D A;  2YBO A;  2EK7 A;  2E0N A;  3UV3 A;  2EL3 A;  2HUQ A;  3NUT A;  2PCH A;  2P6L A;  2E8R A;  2EK3 A;  4MUY A;  3KEF A;  1WDE A;  1PJT A;  2EMR A;  2P6K A;  3ZGL A;  3HH1 A;  3LMM A;  2EH4 A;  3UV7 A;  2EL0 A;  2EJJ A;  3ND1 A;  1VA0 A;  2E07 A;  2DSI A;  3NEI A;  2E16 A;  2OWF A;  1PJQ A;  2EJZ A;  2E08 A;  2E8H A;  2E0K A;  2EEQ A;  2EH2 A;  3DNF A;  2EK2 A;  2EH5 A;  2OWU A;  2P6I A;  3KE9 A;  2EGL A;  2DSG A;  3T0G A;  3F7T A;  3KEM A;  2EMU A;  1VE2 A;  1VCE A;  3KEL A;  2P6D A;  3UWM A;  1PJS A;  2EL1 A;  5HW4 A;  2PCM A;  2DXW A;  2E4R A;  2BB3 A;  3URK A;  4H4E A;  3UTC A;  4N7B A;  2EN5 A;  2EGS A;  2ELD A;  2PB4 A;  1VHV A;  2HR8 A;  2EJK A;  4MUX A;  2P9D A;  2EGB A;  2E7R A;  2OWV A;  2ZVB A;  4MV5 A;  4E16 A;  2EHC A;  2P5F A;  2PCA A;  2ELE A;  2E15 A;  2P2X A;  2EK4 A;  2ZVC A;  3I4T A;  4MV0 A;  1CBF A;  1V9A A;  2YBQ A;  2DV7 A;  2DXV A;  4H4D A;  3SZU A;  2PB5 A;  2E8Q A;  2E8S A;  2DV5 A;  2KYY A;  2ED3 A;  3UTD A;  2PCG A;  2ENI A; 
#chains in the Genus database with same CATH homology
 2CBF A;  3NDC A;  4H4C A;  2DV3 A;  3ZGN A;  2HUV A;  2ED5 A;  2PCI A;  2HUT A;  2DEK A;  3SZL A;  2E4N A;  3KWP A;  2EHL A;  3T0F A;  3SZO A;  2P5C A;  1WNG A;  3TIX B;  2OWG A;  2NPN A;  2EKA A;  3FFY A;  2DSH A;  3UV6 A;  2EL2 A;  1WYZ A;  2PB6 A;  4EB3 A;  2OWK A;  3KE8 A;  2E17 A;  2Z6R A;  2QBU A;  2DXX A;  3FQ6 A;  2DV4 A;  2PCK A;  2HUX A;  1S4D A;  2YBO A;  2EK7 A;  2E0N A;  3UV3 A;  2EL3 A;  2HUQ A;  3NUT A;  2PCH A;  2P6L A;  2E8R A;  2EK3 A;  4MUY A;  3KEF A;  1WDE A;  1PJT A;  2EMR A;  2P6K A;  3ZGL A;  3HH1 A;  3LMM A;  2EH4 A;  3UV7 A;  2EL0 A;  2EJJ A;  3ND1 A;  1VA0 A;  2E07 A;  2DSI A;  3NEI A;  2E16 A;  2OWF A;  1PJQ A;  2EJZ A;  2E08 A;  2E8H A;  2E0K A;  2EEQ A;  2EH2 A;  3DNF A;  2EK2 A;  2EH5 A;  2OWU A;  2P6I A;  3KE9 A;  2EGL A;  2DSG A;  3T0G A;  3F7T A;  3KEM A;  2EMU A;  1VE2 A;  1VCE A;  3KEL A;  2P6D A;  3UWM A;  1PJS A;  2EL1 A;  5HW4 A;  2PCM A;  2DXW A;  2E4R A;  2BB3 A;  3URK A;  4H4E A;  3UTC A;  4N7B A;  2EN5 A;  2EGS A;  2ELD A;  2PB4 A;  1VHV A;  2HR8 A;  2EJK A;  4MUX A;  2P9D A;  2EGB A;  2E7R A;  2OWV A;  2ZVB A;  4MV5 A;  4E16 A;  2EHC A;  2P5F A;  2PCA A;  2ELE A;  2E15 A;  2P2X A;  2EK4 A;  2ZVC A;  3I4T A;  4MV0 A;  1CBF A;  1V9A A;  2YBQ A;  2DV7 A;  2DXV A;  4H4D A;  3SZU A;  2PB5 A;  2E8Q A;  2E8S A;  2DV5 A;  2KYY A;  2ED3 A;  3UTD A;  2PCG A;  2ENI A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2EHLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations