2HR8A

Crystal structure of ph0725 from pyrococcus horikoshii ot3
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGMVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of PH0725 from Pyrococcus horikoshii OT3
rcsb
molecule tags Transferase
source organism Pyrococcus horikoshii
molecule keywords diphthine synthase
total genus 75
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2006-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2hr8A02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2hr8A01
2NPNA 1VCEA 2EK4A 1S4DA 2EJKA 2EMRA 1WDEA 2ED3A 2PCGA 2DSGA 2EK7A 2P9DA 2DSHA 2DSIA 2EL0A 3NEIA 2E7RA 2YBQA 2PB4A 2ENIA 2E4NA 3FQ6A 2EHLA 2PCKA 2ELEA 2DXVA 2EHCA 2EKAA 2P6DA 1PJSA 1PJQA 1CBFA 2EH5A 2PB5A 2OWFA 2DV3A 2ED5A 2ZVCA 3ND1A 3KWPA 2HUXA 2PCIA 2CBFA 2EGLA 2EJZA 2EL3A 2OWVA 2EL1A 2EN5A 2E08A 3FFYA 3I4TA 2P5FA 2PCAA 2EH4A 2EK2A 1V9AA 1PJTA 2EL2A 2P2XA 2PCHA 2E8QA 2DV4A 2HR8A 2OWKA 2DEKA 1WYZA 2EK3A 2P6IA 2E8HA 2DXWA 2EJJA 2EMUA 2DV5A 2P6LA 1VA0A 2HUQA 2P5CA 2PCMA 2EGSA 2DV7A 2ELDA 2E0NA 2E17A 2HUTA 2E4RA 2E15A 2E8SA 2PB6A 2OWUA 2EGBA 1VE2A 2EEQA 2E07A 2E16A 2YBOA 2QBUA 2E0KA 2DXXA 3NDCA 3HH1A 2OWGA 5HW4A 2E8RA 1VHVA 2ZVBA 1WNGA 4E16A 2P6KA 2HUVA 2Z6RA 2BB3A 3NUTA 2EH2A
chains in the Genus database with same CATH superfamily
2NPNA 1VCEA 2EK4A 1S4DA 2EJKA 2EMRA 1WDEA 3SZOA 2ED3A 2PCGA 2DSGA 2EK7A 3TIXB 2P9DA 3ZGLA 2DSHA 2DSIA 2EL0A 3NEIA 2E7RA 2YBQA 2PB4A 2ENIA 3ZGNA 2E4NA 3FQ6A 3SZLA 2EHLA 2PCKA 2ELEA 2DXVA 2EHCA 2EKAA 2P6DA 3UTDA 1PJSA 2KYYA 1PJQA 1CBFA 2EH5A 2PB5A 2OWFA 3SZUA 2DV3A 2ED5A 2ZVCA 3ND1A 3KWPA 3T0FA 3UV7A 2HUXA 2PCIA 2CBFA 2EGLA 4H4EA 4N7BA 2EJZA 3UV3A 4MUXA 2EL3A 2OWVA 2EL1A 3F7TA 4EB3A 2EN5A 2E08A 3FFYA 3I4TA 4H4CA 2P5FA 3UV6A 2PCAA 2EH4A 2EK2A 1V9AA 1PJTA 2EL2A 3LMMA 2P2XA 2PCHA 2E8QA 3KELA 2DV4A 3DNFA 2HR8A 2OWKA 3URKA 2DEKA 1WYZA 2EK3A 2P6IA 2E8HA 4MV0A 2DXWA 2EJJA 2EMUA 2DV5A 2P6LA 1VA0A 2HUQA 2P5CA 2PCMA 2EGSA 3KE8A 2DV7A 2ELDA 2E0NA 2E17A 2HUTA 3KEFA 2E4RA 2E15A 4H4DA 2E8SA 2PB6A 2OWUA 3UTCA 2EGBA 1VE2A 2EEQA 2E07A 2E16A 4MV5A 2YBOA 2QBUA 3KEMA 2E0KA 4MUYA 2DXXA 3NDCA 3HH1A 2OWGA 3T0GA 3UWMA 5HW4A 2E8RA 1VHVA 2ZVBA 1WNGA 4E16A 2P6KA 3KE9A 2HUVA 2Z6RA 2BB3A 3NUTA 2EH2A
chains in the Genus database with same CATH topology
2NPNA 1VCEA 2EK4A 1S4DA 2EJKA 2EMRA 1WDEA 3SZOA 2ED3A 2PCGA 2DSGA 2EK7A 3TIXB 2P9DA 3ZGLA 2DSHA 2DSIA 2EL0A 3NEIA 2E7RA 2YBQA 2PB4A 2ENIA 3ZGNA 2E4NA 3FQ6A 3SZLA 2EHLA 2PCKA 2ELEA 2DXVA 2EHCA 2EKAA 2P6DA 3UTDA 1PJSA 2KYYA 1PJQA 1CBFA 2EH5A 2PB5A 2OWFA 3SZUA 2DV3A 2ED5A 2ZVCA 3ND1A 3KWPA 3T0FA 3UV7A 2HUXA 2PCIA 2CBFA 2EGLA 4H4EA 4N7BA 2EJZA 3UV3A 4MUXA 2EL3A 2OWVA 2EL1A 3F7TA 4EB3A 2EN5A 2E08A 3FFYA 3I4TA 4H4CA 2P5FA 3UV6A 2PCAA 2EH4A 2EK2A 1V9AA 1PJTA 2EL2A 3LMMA 2P2XA 2PCHA 2E8QA 3KELA 2DV4A 3DNFA 2HR8A 2OWKA 3URKA 2DEKA 1WYZA 2EK3A 2P6IA 2E8HA 4MV0A 2DXWA 2EJJA 2EMUA 2DV5A 2P6LA 1VA0A 2HUQA 2P5CA 2PCMA 2EGSA 3KE8A 2DV7A 2ELDA 2E0NA 2E17A 2HUTA 3KEFA 2E4RA 2E15A 4H4DA 2E8SA 2PB6A 2OWUA 3UTCA 2EGBA 1VE2A 2EEQA 2E07A 2E16A 4MV5A 2YBOA 2QBUA 3KEMA 2E0KA 4MUYA 2DXXA 3NDCA 3HH1A 2OWGA 3T0GA 3UWMA 5HW4A 2E8RA 1VHVA 2ZVBA 1WNGA 4E16A 2P6KA 3KE9A 2HUVA 2Z6RA 2BB3A 3NUTA 2EH2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NPN A;  1VCE A;  2EK4 A;  1S4D A;  2EJK A;  2EMR A;  1WDE A;  2ED3 A;  2PCG A;  2DSG A;  2EK7 A;  2P9D A;  2DSH A;  2DSI A;  2EL0 A;  3NEI A;  2E7R A;  2YBQ A;  2PB4 A;  2ENI A;  2E4N A;  3FQ6 A;  2EHL A;  2PCK A;  2ELE A;  2DXV A;  2EHC A;  2EKA A;  2P6D A;  1PJS A;  1PJQ A;  1CBF A;  2EH5 A;  2PB5 A;  2OWF A;  2DV3 A;  2ED5 A;  2ZVC A;  3ND1 A;  3KWP A;  2HUX A;  2PCI A;  2CBF A;  2EGL A;  2EJZ A;  2EL3 A;  2OWV A;  2EL1 A;  2EN5 A;  2E08 A;  3FFY A;  3I4T A;  2P5F A;  2PCA A;  2EH4 A;  2EK2 A;  1V9A A;  1PJT A;  2EL2 A;  2P2X A;  2PCH A;  2E8Q A;  2DV4 A;  2HR8 A;  2OWK A;  2DEK A;  1WYZ A;  2EK3 A;  2P6I A;  2E8H A;  2DXW A;  2EJJ A;  2EMU A;  2DV5 A;  2P6L A;  1VA0 A;  2HUQ A;  2P5C A;  2PCM A;  2EGS A;  2DV7 A;  2ELD A;  2E0N A;  2E17 A;  2HUT A;  2E4R A;  2E15 A;  2E8S A;  2PB6 A;  2OWU A;  2EGB A;  1VE2 A;  2EEQ A;  2E07 A;  2E16 A;  2YBO A;  2QBU A;  2E0K A;  2DXX A;  3NDC A;  3HH1 A;  2OWG A;  5HW4 A;  2E8R A;  1VHV A;  2ZVB A;  1WNG A;  4E16 A;  2P6K A;  2HUV A;  2Z6R A;  2BB3 A;  3NUT A;  2EH2 A; 
#chains in the Genus database with same CATH topology
 2NPN A;  1VCE A;  2EK4 A;  1S4D A;  2EJK A;  2EMR A;  1WDE A;  3SZO A;  2ED3 A;  2PCG A;  2DSG A;  2EK7 A;  3TIX B;  2P9D A;  3ZGL A;  2DSH A;  2DSI A;  2EL0 A;  3NEI A;  2E7R A;  2YBQ A;  2PB4 A;  2ENI A;  3ZGN A;  2E4N A;  3FQ6 A;  3SZL A;  2EHL A;  2PCK A;  2ELE A;  2DXV A;  2EHC A;  2EKA A;  2P6D A;  3UTD A;  1PJS A;  2KYY A;  1PJQ A;  1CBF A;  2EH5 A;  2PB5 A;  2OWF A;  3SZU A;  2DV3 A;  2ED5 A;  2ZVC A;  3ND1 A;  3KWP A;  3T0F A;  3UV7 A;  2HUX A;  2PCI A;  2CBF A;  2EGL A;  4H4E A;  4N7B A;  2EJZ A;  3UV3 A;  4MUX A;  2EL3 A;  2OWV A;  2EL1 A;  3F7T A;  4EB3 A;  2EN5 A;  2E08 A;  3FFY A;  3I4T A;  4H4C A;  2P5F A;  3UV6 A;  2PCA A;  2EH4 A;  2EK2 A;  1V9A A;  1PJT A;  2EL2 A;  3LMM A;  2P2X A;  2PCH A;  2E8Q A;  3KEL A;  2DV4 A;  3DNF A;  2HR8 A;  2OWK A;  3URK A;  2DEK A;  1WYZ A;  2EK3 A;  2P6I A;  2E8H A;  4MV0 A;  2DXW A;  2EJJ A;  2EMU A;  2DV5 A;  2P6L A;  1VA0 A;  2HUQ A;  2P5C A;  2PCM A;  2EGS A;  3KE8 A;  2DV7 A;  2ELD A;  2E0N A;  2E17 A;  2HUT A;  3KEF A;  2E4R A;  2E15 A;  4H4D A;  2E8S A;  2PB6 A;  2OWU A;  3UTC A;  2EGB A;  1VE2 A;  2EEQ A;  2E07 A;  2E16 A;  4MV5 A;  2YBO A;  2QBU A;  3KEM A;  2E0K A;  4MUY A;  2DXX A;  3NDC A;  3HH1 A;  2OWG A;  3T0G A;  3UWM A;  5HW4 A;  2E8R A;  1VHV A;  2ZVB A;  1WNG A;  4E16 A;  2P6K A;  3KE9 A;  2HUV A;  2Z6R A;  2BB3 A;  3NUT A;  2EH2 A; 
#chains in the Genus database with same CATH homology
 2NPN A;  1VCE A;  2EK4 A;  1S4D A;  2EJK A;  2EMR A;  1WDE A;  3SZO A;  2ED3 A;  2PCG A;  2DSG A;  2EK7 A;  3TIX B;  2P9D A;  3ZGL A;  2DSH A;  2DSI A;  2EL0 A;  3NEI A;  2E7R A;  2YBQ A;  2PB4 A;  2ENI A;  3ZGN A;  2E4N A;  3FQ6 A;  3SZL A;  2EHL A;  2PCK A;  2ELE A;  2DXV A;  2EHC A;  2EKA A;  2P6D A;  3UTD A;  1PJS A;  2KYY A;  1PJQ A;  1CBF A;  2EH5 A;  2PB5 A;  2OWF A;  3SZU A;  2DV3 A;  2ED5 A;  2ZVC A;  3ND1 A;  3KWP A;  3T0F A;  3UV7 A;  2HUX A;  2PCI A;  2CBF A;  2EGL A;  4H4E A;  4N7B A;  2EJZ A;  3UV3 A;  4MUX A;  2EL3 A;  2OWV A;  2EL1 A;  3F7T A;  4EB3 A;  2EN5 A;  2E08 A;  3FFY A;  3I4T A;  4H4C A;  2P5F A;  3UV6 A;  2PCA A;  2EH4 A;  2EK2 A;  1V9A A;  1PJT A;  2EL2 A;  3LMM A;  2P2X A;  2PCH A;  2E8Q A;  3KEL A;  2DV4 A;  3DNF A;  2HR8 A;  2OWK A;  3URK A;  2DEK A;  1WYZ A;  2EK3 A;  2P6I A;  2E8H A;  4MV0 A;  2DXW A;  2EJJ A;  2EMU A;  2DV5 A;  2P6L A;  1VA0 A;  2HUQ A;  2P5C A;  2PCM A;  2EGS A;  3KE8 A;  2DV7 A;  2ELD A;  2E0N A;  2E17 A;  2HUT A;  3KEF A;  2E4R A;  2E15 A;  4H4D A;  2E8S A;  2PB6 A;  2OWU A;  3UTC A;  2EGB A;  1VE2 A;  2EEQ A;  2E07 A;  2E16 A;  4MV5 A;  2YBO A;  2QBU A;  3KEM A;  2E0K A;  4MUY A;  2DXX A;  3NDC A;  3HH1 A;  2OWG A;  3T0G A;  3UWM A;  5HW4 A;  2E8R A;  1VHV A;  2ZVB A;  1WNG A;  4E16 A;  2P6K A;  3KE9 A;  2HUV A;  2Z6R A;  2BB3 A;  3NUT A;  2EH2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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