2P6D | Genus

Total Genus 76

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	76
sequence length	265
structure length	265
Chain Sequence	MVLYFIGLGLYDERDITVKGLMIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Pyrococcus horikoshii
publication title	Crystal structure of PH0725 from Pyrococcus horikoshii OT3 rcsb
molecule keywords	diphthine synthase
total genus	76
structure length	265
sequence length	265
chains with identical sequence	B
ec nomenclature	ec 2.1.1.98: Diphthine synthase.
pdb deposition date	2007-03-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00590	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.950.10	Alpha Beta	2-Layer Sandwich	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	2p6dA02
3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase; domain 1	Cobalt-precorrin-4 Transmethylase; Domain 1	2p6dA01

2E15A 2DXVA 2E8HA 2ELDA 2EGLA 2EN5A 2P6LA 2EL3A 1CBFA 2P5FA 2EJKA 2BB3A 1VA0A 2ZVCA 2E16A 2DEKA 2EL2A 1WYZA 2EJJA 2Z6RA 2ENIA 2QBUA 2PCGA 2P5CA 2DV7A 2HUVA 2EHLA 2EMRA 2OWGA 2EKAA 2DXXA 2PB5A 2EK2A 2E0NA 2ED3A 4E16A 1VE2A 5HW4A 2OWFA 1VCEA 1PJQA 2E17A 2ELEA 2EK3A 2EEQA 2P9DA 2EL0A 2EMUA 2EH4A 2E4RA 3NDCA 2P6IA 2EGBA 2PCHA 2E4NA 2P2XA 2EK7A 3ND1A 3FQ6A 2HUQA 2EH5A 2DSIA 3HH1A 2E8QA 2EGSA 1VHVA 2E8RA 2HUTA 1PJTA 2E08A 2ZVBA 1WNGA 2CBFA 2E7RA 2PCMA 2PCKA 2PCAA 2PB6A 2EHCA 1V9AA 2E07A 2E8SA 2DV4A 2DV3A 2PB4A 2EJZA 2NPNA 2HUXA 3I4TA 2EK4A 2EL1A 1S4DA 2YBOA 2DSGA 2DV5A 2P6KA 3FFYA 2YBQA 2OWVA 2P6DA 1WDEA 2DXWA 2E0KA 3NUTA 3NEIA 3KWPA 2EH2A 2DSHA 2OWKA 2HR8A 2PCIA 1PJSA 2ED5A 2OWUA
chains in the Genus database with same CATH superfamily

2E15A 2DXVA 2E8HA 2ELDA 2KYYA 2EGLA 2EN5A 2P6LA 2EL3A 4MV0A 3KE8A 1CBFA 2P5FA 2EJKA 2BB3A 3KEMA 3TIXB 3KE9A 1VA0A 2ZVCA 4N7BA 2E16A 4EB3A 2DEKA 2EL2A 1WYZA 3F7TA 2EJJA 2Z6RA 2ENIA 2QBUA 2PCGA 4H4EA 2P5CA 2DV7A 3SZOA 2HUVA 2EHLA 2EMRA 2OWGA 2EKAA 2DXXA 3T0FA 2PB5A 2EK2A 4H4DA 2E0NA 2ED3A 4E16A 1VE2A 3KELA 5HW4A 2OWFA 1VCEA 1PJQA 2E17A 2ELEA 2EK3A 2EEQA 2P9DA 2EL0A 3UV3A 2EMUA 2EH4A 2E4RA 3NDCA 3UWMA 4MUYA 2P6IA 2EGBA 2PCHA 2E4NA 3KEFA 2P2XA 2EK7A 3ND1A 3FQ6A 2HUQA 2EH5A 2DSIA 3HH1A 2E8QA 2EGSA 1VHVA 2E8RA 2HUTA 1PJTA 2E08A 2ZVBA 1WNGA 3UTDA 2CBFA 2E7RA 2PCMA 2PCKA 2PCAA 2PB6A 3LMMA 2EHCA 1V9AA 3UV6A 2E07A 2E8SA 3UV7A 2DV4A 2DV3A 3SZLA 2PB4A 3URKA 2EJZA 2NPNA 2HUXA 3SZUA 3I4TA 3T0GA 2EK4A 2EL1A 1S4DA 2YBOA 2DSGA 2DV5A 2P6KA 3FFYA 2YBQA 2OWVA 2P6DA 1WDEA 2DXWA 2E0KA 3NUTA 3UTCA 3NEIA 3KWPA 4MUXA 3ZGNA 3ZGLA 2EH2A 3DNFA 2DSHA 2OWKA 2HR8A 2PCIA 4MV5A 1PJSA 2ED5A 2OWUA 4H4CA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2E15 A;  2DXV A;  2E8H A;  2ELD A;  2EGL A;  2EN5 A;  2P6L A;  2EL3 A;  1CBF A;  2P5F A;  2EJK A;  2BB3 A;  1VA0 A;  2ZVC A;  2E16 A;  2DEK A;  2EL2 A;  1WYZ A;  2EJJ A;  2Z6R A;  2ENI A;  2QBU A;  2PCG A;  2P5C A;  2DV7 A;  2HUV A;  2EHL A;  2EMR A;  2OWG A;  2EKA A;  2DXX A;  2PB5 A;  2EK2 A;  2E0N A;  2ED3 A;  4E16 A;  1VE2 A;  5HW4 A;  2OWF A;  1VCE A;  1PJQ A;  2E17 A;  2ELE A;  2EK3 A;  2EEQ A;  2P9D A;  2EL0 A;  2EMU A;  2EH4 A;  2E4R A;  3NDC A;  2P6I A;  2EGB A;  2PCH A;  2E4N A;  2P2X A;  2EK7 A;  3ND1 A;  3FQ6 A;  2HUQ A;  2EH5 A;  2DSI A;  3HH1 A;  2E8Q A;  2EGS A;  1VHV A;  2E8R A;  2HUT A;  1PJT A;  2E08 A;  2ZVB A;  1WNG A;  2CBF A;  2E7R A;  2PCM A;  2PCK A;  2PCA A;  2PB6 A;  2EHC A;  1V9A A;  2E07 A;  2E8S A;  2DV4 A;  2DV3 A;  2PB4 A;  2EJZ A;  2NPN A;  2HUX A;  3I4T A;  2EK4 A;  2EL1 A;  1S4D A;  2YBO A;  2DSG A;  2DV5 A;  2P6K A;  3FFY A;  2YBQ A;  2OWV A;  2P6D A;  1WDE A;  2DXW A;  2E0K A;  3NUT A;  3NEI A;  3KWP A;  2EH2 A;  2DSH A;  2OWK A;  2HR8 A;  2PCI A;  1PJS A;  2ED5 A;  2OWU A; 
#chains in the Genus database with same CATH topology
 2E15 A;  2DXV A;  2E8H A;  2ELD A;  2KYY A;  2EGL A;  2EN5 A;  2P6L A;  2EL3 A;  4MV0 A;  3KE8 A;  1CBF A;  2P5F A;  2EJK A;  2BB3 A;  3KEM A;  3TIX B;  3KE9 A;  1VA0 A;  2ZVC A;  4N7B A;  2E16 A;  4EB3 A;  2DEK A;  2EL2 A;  1WYZ A;  3F7T A;  2EJJ A;  2Z6R A;  2ENI A;  2QBU A;  2PCG A;  4H4E A;  2P5C A;  2DV7 A;  3SZO A;  2HUV A;  2EHL A;  2EMR A;  2OWG A;  2EKA A;  2DXX A;  3T0F A;  2PB5 A;  2EK2 A;  4H4D A;  2E0N A;  2ED3 A;  4E16 A;  1VE2 A;  3KEL A;  5HW4 A;  2OWF A;  1VCE A;  1PJQ A;  2E17 A;  2ELE A;  2EK3 A;  2EEQ A;  2P9D A;  2EL0 A;  3UV3 A;  2EMU A;  2EH4 A;  2E4R A;  3NDC A;  3UWM A;  4MUY A;  2P6I A;  2EGB A;  2PCH A;  2E4N A;  3KEF A;  2P2X A;  2EK7 A;  3ND1 A;  3FQ6 A;  2HUQ A;  2EH5 A;  2DSI A;  3HH1 A;  2E8Q A;  2EGS A;  1VHV A;  2E8R A;  2HUT A;  1PJT A;  2E08 A;  2ZVB A;  1WNG A;  3UTD A;  2CBF A;  2E7R A;  2PCM A;  2PCK A;  2PCA A;  2PB6 A;  3LMM A;  2EHC A;  1V9A A;  3UV6 A;  2E07 A;  2E8S A;  3UV7 A;  2DV4 A;  2DV3 A;  3SZL A;  2PB4 A;  3URK A;  2EJZ A;  2NPN A;  2HUX A;  3SZU A;  3I4T A;  3T0G A;  2EK4 A;  2EL1 A;  1S4D A;  2YBO A;  2DSG A;  2DV5 A;  2P6K A;  3FFY A;  2YBQ A;  2OWV A;  2P6D A;  1WDE A;  2DXW A;  2E0K A;  3NUT A;  3UTC A;  3NEI A;  3KWP A;  4MUX A;  3ZGN A;  3ZGL A;  2EH2 A;  3DNF A;  2DSH A;  2OWK A;  2HR8 A;  2PCI A;  4MV5 A;  1PJS A;  2ED5 A;  2OWU A;  4H4C A; 
#chains in the Genus database with same CATH homology
 2E15 A;  2DXV A;  2E8H A;  2ELD A;  2KYY A;  2EGL A;  2EN5 A;  2P6L A;  2EL3 A;  4MV0 A;  3KE8 A;  1CBF A;  2P5F A;  2EJK A;  2BB3 A;  3KEM A;  3TIX B;  3KE9 A;  1VA0 A;  2ZVC A;  4N7B A;  2E16 A;  4EB3 A;  2DEK A;  2EL2 A;  1WYZ A;  3F7T A;  2EJJ A;  2Z6R A;  2ENI A;  2QBU A;  2PCG A;  4H4E A;  2P5C A;  2DV7 A;  3SZO A;  2HUV A;  2EHL A;  2EMR A;  2OWG A;  2EKA A;  2DXX A;  3T0F A;  2PB5 A;  2EK2 A;  4H4D A;  2E0N A;  2ED3 A;  4E16 A;  1VE2 A;  3KEL A;  5HW4 A;  2OWF A;  1VCE A;  1PJQ A;  2E17 A;  2ELE A;  2EK3 A;  2EEQ A;  2P9D A;  2EL0 A;  3UV3 A;  2EMU A;  2EH4 A;  2E4R A;  3NDC A;  3UWM A;  4MUY A;  2P6I A;  2EGB A;  2PCH A;  2E4N A;  3KEF A;  2P2X A;  2EK7 A;  3ND1 A;  3FQ6 A;  2HUQ A;  2EH5 A;  2DSI A;  3HH1 A;  2E8Q A;  2EGS A;  1VHV A;  2E8R A;  2HUT A;  1PJT A;  2E08 A;  2ZVB A;  1WNG A;  3UTD A;  2CBF A;  2E7R A;  2PCM A;  2PCK A;  2PCA A;  2PB6 A;  3LMM A;  2EHC A;  1V9A A;  3UV6 A;  2E07 A;  2E8S A;  3UV7 A;  2DV4 A;  2DV3 A;  3SZL A;  2PB4 A;  3URK A;  2EJZ A;  2NPN A;  2HUX A;  3SZU A;  3I4T A;  3T0G A;  2EK4 A;  2EL1 A;  1S4D A;  2YBO A;  2DSG A;  2DV5 A;  2P6K A;  3FFY A;  2YBQ A;  2OWV A;  2P6D A;  1WDE A;  2DXW A;  2E0K A;  3NUT A;  3UTC A;  3NEI A;  3KWP A;  4MUX A;  3ZGN A;  3ZGL A;  2EH2 A;  3DNF A;  2DSH A;  2OWK A;  2HR8 A;  2PCI A;  4MV5 A;  1PJS A;  2ED5 A;  2OWU A;  4H4C A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2P6DA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations