2PCH | Genus

Total Genus 86

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	86
sequence length	265
structure length	265
Chain Sequence	MVLYFIGLGLYDERDITVKGLECAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Pyrococcus horikoshii
publication title	Crystal structure of PH0725 from Pyrococcus horikoshii OT3 rcsb
molecule keywords	Probable diphthine synthase
total genus	86
structure length	265
sequence length	265
chains with identical sequence	B
ec nomenclature	ec 2.1.1.98: Diphthine synthase.
pdb deposition date	2007-03-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00590	TP_methylase	Tetrapyrrole (Corrin/Porphyrin) Methylases

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.950.10	Alpha Beta	2-Layer Sandwich	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2	2pchA02
3.40.1010.10	Alpha Beta	3-Layer(aba) Sandwich	Cobalt-precorrin-4 Transmethylase; domain 1	Cobalt-precorrin-4 Transmethylase; Domain 1	2pchA01

2EHLA 2P6KA 2EJJA 1S4DA 2ED3A 2DEKA 2P5CA 2EJZA 2E0KA 2EK3A 1WNGA 2ENIA 2EN5A 2P2XA 2E8QA 2P6IA 2DXWA 1PJTA 2P5FA 2QBUA 2P6DA 2EK4A 1V9AA 2E4RA 1VHVA 2DSHA 2EK2A 2EKAA 3NUTA 2DV3A 1PJSA 2EMRA 2EL2A 2PB6A 2ELEA 2EEQA 4E16A 2E4NA 1WYZA 2DXXA 2YBOA 2E8RA 2P6LA 2PCKA 2DSIA 2PB4A 2EL1A 2EH4A 3NEIA 1VE2A 2OWVA 1VA0A 2PCAA 2ELDA 2DV7A 2HR8A 5HW4A 2EMUA 2ZVBA 2PCGA 1PJQA 2EGLA 2OWFA 3FQ6A 3NDCA 3FFYA 2HUXA 2EHCA 2EGSA 2EJKA 2OWKA 2E0NA 2EH5A 2DSGA 2YBQA 3I4TA 2P9DA 2HUQA 2PB5A 1WDEA 2BB3A 2E07A 1VCEA 2EK7A 1CBFA 2E7RA 2EGBA 3KWPA 2PCIA 2E08A 2ZVCA 2E8HA 2DV4A 3ND1A 2E17A 3HH1A 2HUTA 2EH2A 2Z6RA 2DV5A 2E8SA 2E16A 2NPNA 2ED5A 2E15A 2CBFA 2OWUA 2HUVA 2PCHA 2EL3A 2EL0A 2PCMA 2OWGA 2DXVA
chains in the Genus database with same CATH superfamily

2EHLA 2P6KA 2EJJA 1S4DA 3T0FA 2ED3A 2DEKA 2P5CA 2EJZA 2E0KA 3KEMA 2EK3A 3TIXB 3UV6A 1WNGA 2ENIA 2EN5A 2P2XA 2E8QA 2P6IA 2DXWA 4EB3A 3KELA 4N7BA 3ZGLA 1PJTA 2P5FA 2QBUA 2P6DA 2EK4A 1V9AA 2E4RA 4MV5A 1VHVA 2DSHA 2EK2A 2EKAA 3NUTA 2KYYA 2DV3A 1PJSA 2EMRA 2EL2A 2PB6A 2ELEA 2EEQA 4E16A 2E4NA 3SZUA 3DNFA 1WYZA 2DXXA 2YBOA 3KE9A 3UTCA 2E8RA 2P6LA 2PCKA 2DSIA 2PB4A 2EL1A 2EH4A 3NEIA 1VE2A 2OWVA 1VA0A 2PCAA 3SZLA 2ELDA 2DV7A 2HR8A 5HW4A 2EMUA 3T0GA 2ZVBA 2PCGA 1PJQA 2EGLA 2OWFA 3FQ6A 3URKA 3NDCA 3FFYA 2HUXA 2EHCA 4H4DA 3UTDA 2EGSA 2EJKA 2OWKA 2E0NA 3KEFA 2EH5A 2DSGA 2YBQA 3I4TA 2P9DA 3UWMA 2HUQA 2PB5A 1WDEA 2BB3A 2E07A 1VCEA 3KE8A 3SZOA 2EK7A 1CBFA 2E7RA 2EGBA 4MV0A 3KWPA 2PCIA 2E08A 3UV7A 2ZVCA 2E8HA 2DV4A 3ND1A 3F7TA 2E17A 3HH1A 2HUTA 2EH2A 2Z6RA 4H4EA 4MUYA 2DV5A 2E8SA 2E16A 3UV3A 3LMMA 2NPNA 4H4CA 2ED5A 2E15A 2CBFA 2OWUA 2HUVA 4MUXA 2PCHA 2EL3A 2EL0A 3ZGNA 2PCMA 2OWGA 2DXVA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2EHL A;  2P6K A;  2EJJ A;  1S4D A;  2ED3 A;  2DEK A;  2P5C A;  2EJZ A;  2E0K A;  2EK3 A;  1WNG A;  2ENI A;  2EN5 A;  2P2X A;  2E8Q A;  2P6I A;  2DXW A;  1PJT A;  2P5F A;  2QBU A;  2P6D A;  2EK4 A;  1V9A A;  2E4R A;  1VHV A;  2DSH A;  2EK2 A;  2EKA A;  3NUT A;  2DV3 A;  1PJS A;  2EMR A;  2EL2 A;  2PB6 A;  2ELE A;  2EEQ A;  4E16 A;  2E4N A;  1WYZ A;  2DXX A;  2YBO A;  2E8R A;  2P6L A;  2PCK A;  2DSI A;  2PB4 A;  2EL1 A;  2EH4 A;  3NEI A;  1VE2 A;  2OWV A;  1VA0 A;  2PCA A;  2ELD A;  2DV7 A;  2HR8 A;  5HW4 A;  2EMU A;  2ZVB A;  2PCG A;  1PJQ A;  2EGL A;  2OWF A;  3FQ6 A;  3NDC A;  3FFY A;  2HUX A;  2EHC A;  2EGS A;  2EJK A;  2OWK A;  2E0N A;  2EH5 A;  2DSG A;  2YBQ A;  3I4T A;  2P9D A;  2HUQ A;  2PB5 A;  1WDE A;  2BB3 A;  2E07 A;  1VCE A;  2EK7 A;  1CBF A;  2E7R A;  2EGB A;  3KWP A;  2PCI A;  2E08 A;  2ZVC A;  2E8H A;  2DV4 A;  3ND1 A;  2E17 A;  3HH1 A;  2HUT A;  2EH2 A;  2Z6R A;  2DV5 A;  2E8S A;  2E16 A;  2NPN A;  2ED5 A;  2E15 A;  2CBF A;  2OWU A;  2HUV A;  2PCH A;  2EL3 A;  2EL0 A;  2PCM A;  2OWG A;  2DXV A; 
#chains in the Genus database with same CATH topology
 2EHL A;  2P6K A;  2EJJ A;  1S4D A;  3T0F A;  2ED3 A;  2DEK A;  2P5C A;  2EJZ A;  2E0K A;  3KEM A;  2EK3 A;  3TIX B;  3UV6 A;  1WNG A;  2ENI A;  2EN5 A;  2P2X A;  2E8Q A;  2P6I A;  2DXW A;  4EB3 A;  3KEL A;  4N7B A;  3ZGL A;  1PJT A;  2P5F A;  2QBU A;  2P6D A;  2EK4 A;  1V9A A;  2E4R A;  4MV5 A;  1VHV A;  2DSH A;  2EK2 A;  2EKA A;  3NUT A;  2KYY A;  2DV3 A;  1PJS A;  2EMR A;  2EL2 A;  2PB6 A;  2ELE A;  2EEQ A;  4E16 A;  2E4N A;  3SZU A;  3DNF A;  1WYZ A;  2DXX A;  2YBO A;  3KE9 A;  3UTC A;  2E8R A;  2P6L A;  2PCK A;  2DSI A;  2PB4 A;  2EL1 A;  2EH4 A;  3NEI A;  1VE2 A;  2OWV A;  1VA0 A;  2PCA A;  3SZL A;  2ELD A;  2DV7 A;  2HR8 A;  5HW4 A;  2EMU A;  3T0G A;  2ZVB A;  2PCG A;  1PJQ A;  2EGL A;  2OWF A;  3FQ6 A;  3URK A;  3NDC A;  3FFY A;  2HUX A;  2EHC A;  4H4D A;  3UTD A;  2EGS A;  2EJK A;  2OWK A;  2E0N A;  3KEF A;  2EH5 A;  2DSG A;  2YBQ A;  3I4T A;  2P9D A;  3UWM A;  2HUQ A;  2PB5 A;  1WDE A;  2BB3 A;  2E07 A;  1VCE A;  3KE8 A;  3SZO A;  2EK7 A;  1CBF A;  2E7R A;  2EGB A;  4MV0 A;  3KWP A;  2PCI A;  2E08 A;  3UV7 A;  2ZVC A;  2E8H A;  2DV4 A;  3ND1 A;  3F7T A;  2E17 A;  3HH1 A;  2HUT A;  2EH2 A;  2Z6R A;  4H4E A;  4MUY A;  2DV5 A;  2E8S A;  2E16 A;  3UV3 A;  3LMM A;  2NPN A;  4H4C A;  2ED5 A;  2E15 A;  2CBF A;  2OWU A;  2HUV A;  4MUX A;  2PCH A;  2EL3 A;  2EL0 A;  3ZGN A;  2PCM A;  2OWG A;  2DXV A; 
#chains in the Genus database with same CATH homology
 2EHL A;  2P6K A;  2EJJ A;  1S4D A;  3T0F A;  2ED3 A;  2DEK A;  2P5C A;  2EJZ A;  2E0K A;  3KEM A;  2EK3 A;  3TIX B;  3UV6 A;  1WNG A;  2ENI A;  2EN5 A;  2P2X A;  2E8Q A;  2P6I A;  2DXW A;  4EB3 A;  3KEL A;  4N7B A;  3ZGL A;  1PJT A;  2P5F A;  2QBU A;  2P6D A;  2EK4 A;  1V9A A;  2E4R A;  4MV5 A;  1VHV A;  2DSH A;  2EK2 A;  2EKA A;  3NUT A;  2KYY A;  2DV3 A;  1PJS A;  2EMR A;  2EL2 A;  2PB6 A;  2ELE A;  2EEQ A;  4E16 A;  2E4N A;  3SZU A;  3DNF A;  1WYZ A;  2DXX A;  2YBO A;  3KE9 A;  3UTC A;  2E8R A;  2P6L A;  2PCK A;  2DSI A;  2PB4 A;  2EL1 A;  2EH4 A;  3NEI A;  1VE2 A;  2OWV A;  1VA0 A;  2PCA A;  3SZL A;  2ELD A;  2DV7 A;  2HR8 A;  5HW4 A;  2EMU A;  3T0G A;  2ZVB A;  2PCG A;  1PJQ A;  2EGL A;  2OWF A;  3FQ6 A;  3URK A;  3NDC A;  3FFY A;  2HUX A;  2EHC A;  4H4D A;  3UTD A;  2EGS A;  2EJK A;  2OWK A;  2E0N A;  3KEF A;  2EH5 A;  2DSG A;  2YBQ A;  3I4T A;  2P9D A;  3UWM A;  2HUQ A;  2PB5 A;  1WDE A;  2BB3 A;  2E07 A;  1VCE A;  3KE8 A;  3SZO A;  2EK7 A;  1CBF A;  2E7R A;  2EGB A;  4MV0 A;  3KWP A;  2PCI A;  2E08 A;  3UV7 A;  2ZVC A;  2E8H A;  2DV4 A;  3ND1 A;  3F7T A;  2E17 A;  3HH1 A;  2HUT A;  2EH2 A;  2Z6R A;  4H4E A;  4MUY A;  2DV5 A;  2E8S A;  2E16 A;  3UV3 A;  3LMM A;  2NPN A;  4H4C A;  2ED5 A;  2E15 A;  2CBF A;  2OWU A;  2HUV A;  4MUX A;  2PCH A;  2EL3 A;  2EL0 A;  3ZGN A;  2PCM A;  2OWG A;  2DXV A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2PCHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations