1ZJRA

Crystal structure of a. aeolicus trmh/spou trna modifying enzyme
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
197
structure length
197
Chain Sequence
LVLEKRLKRLREVLEKRQKDLIVFADNVKNEHNFSAIVRTCDAVGVLYLYYYHAEGKKAKINEGITQGSHKWVFIEKVDNPVQKLLEFKNRGFQIVATWLSKESVNFREVDYTKPTVLVVGNELQGVSPEIVEIADKKIVIPMYGMAQSLNVSVATGIILYEAQRQREEKGMYSRPSLSEEEIQKILKKWAYEDVIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Aquifex aeolicus
publication title Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.
pubmed doi rcsb
molecule keywords tRNA (Guanosine-2'-O-)-methyltransferase
total genus 69
structure length 197
sequence length 197
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.34: tRNA (guanosine(18)-2'-O)-methyltransferase.
pdb deposition date 2005-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
A PF12105 SpoU_methylas_C SpoU, rRNA methylase, C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1zjrA00
4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 4YVHA 4YQ7A 4YQJA 1MXIA 2O3AA 3O7BA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 4YQ5A 3IC6A 4YQTA 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 3N4KA 4YVKA 3N4JA 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 1P9PA 3L8UA 1UAJA 4MCCA 4CNDA 4YQLA 4YQGA 3BBEA 1UALA 1K3RA 1VH0A 1TO0A 1UAMA 4IG6A 1GZ0A 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4JAKA 4YVIA 4YQDA 4YVJA 4XBOA 2CX8A 3IEFA 3QUVA 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 5GMBA 4X3MA 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4CNGA 4YQ9A 3KW2A 2QMMA 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3AIAA 4PZKA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 4KGNA 4YPYA
chains in the Genus database with same CATH superfamily
4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 4YVHA 4YQ7A 4YQJA 1MXIA 2O3AA 3O7BA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 4JWGA 4YQ5A 3IC6A 4YQTA 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 4FMWA 3N4KA 4JWJA 4YVKA 3N4JA 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 1P9PA 3L8UA 1UAJA 4MCCA 4CNDA 4YQLA 4YQGA 3BBEA 1UALA 1K3RA 1VH0A 1TO0A 1UAMA 4IG6A 1GZ0A 4JWHA 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4JAKA 4YVIA 4YQDA 4YVJA 4XBOA 2CX8A 3IEFA 3QUVA 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 5GMBA 4X3MA 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4CNGA 4YQ9A 3KW2A 2QMMA 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3AIAA 4PZKA 4JWFA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 4KGNA 4YPYA
chains in the Genus database with same CATH topology
4YPWA 4YQ8A 1VHYA 3ILKA 3AXZA 4L69A 4YVHA 4YQ7A 4YQJA 1MXIA 2O3AA 3O7BA 3NK7A 4FAKA 2EGVA 3OIJA 1OY5A 3DCMX 4YVGA 4YQKA 4JWGA 4YQ5A 3IC6A 4YQTA 1IPAA 4YQPA 4YQCA 4YQ4A 2HA8A 4YQ3A 3BBDA 4FMWA 3N4KA 4JWJA 4YVKA 3N4JA 4YQ2A 3OINA 4YQ6A 1J85A 4J3CA 4X3LA 4YQAA 1NXZA 3BBHA 5GMCA 1P9PA 3L8UA 1UAJA 4MCCA 4CNDA 4YQLA 4YQGA 3BBEA 1UALA 1K3RA 1VH0A 1TO0A 1UAMA 4IG6A 1GZ0A 4JWHA 4MCDA 4YQNA 3GYQA 4YPXA 2I6DA 4YQIA 1O6DA 1UAKA 1V6ZA 4CNFA 4YQRA 1X7PA 5FAIA 3AI9X 2Z0YA 5CO4A 4JALA 3ONPA 3NK6A 1NS5A 4YPZA 4JAKA 4YVIA 4YQDA 4YVJA 4XBOA 2CX8A 3IEFA 3QUVA 5GM8A 4YQ1A 1X7OA 1V2XA 4H3ZA 5GMBA 4X3MA 4E8BA 4YQOA 3OIIA 1VHKA 2V3KA 3KNUA 4RG1A 4CNGA 4YQ9A 3KW2A 2QMMA 3E5YA 2EGWA 3KY7A 4KDZA 4YQSA 2YY8A 4YQQA 2V3JA 1Z85A 3KTYA 4YQ0A 4H3YA 1ZJRA 3AIAA 4PZKA 4JWFA 2QWVA 4MCBA 4YQBA 5D9FA 4CNEA 4KGNA 4YPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  4YVH A;  4YQ7 A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  4YQ5 A;  3IC6 A;  4YQT A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  3N4K A;  4YVK A;  3N4J A;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  1P9P A;  3L8U A;  1UAJ A;  4MCC A;  4CND A;  4YQL A;  4YQG A;  3BBE A;  1UAL A;  1K3R A;  1VH0 A;  1TO0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4JAK A;  4YVI A;  4YQD A;  4YVJ A;  4XBO A;  2CX8 A;  3IEF A;  3QUV A;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  5GMB A;  4X3M A;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4CNG A;  4YQ9 A;  3KW2 A;  2QMM A;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3AIA A;  4PZK A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  4KGN A;  4YPY A; 
#chains in the Genus database with same CATH topology
 4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  4YVH A;  4YQ7 A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  4JWG A;  4YQ5 A;  3IC6 A;  4YQT A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  4FMW A;  3N4K A;  4JWJ A;  4YVK A;  3N4J A;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  1P9P A;  3L8U A;  1UAJ A;  4MCC A;  4CND A;  4YQL A;  4YQG A;  3BBE A;  1UAL A;  1K3R A;  1VH0 A;  1TO0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4JWH A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4JAK A;  4YVI A;  4YQD A;  4YVJ A;  4XBO A;  2CX8 A;  3IEF A;  3QUV A;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  5GMB A;  4X3M A;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4CNG A;  4YQ9 A;  3KW2 A;  2QMM A;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3AIA A;  4PZK A;  4JWF A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  4KGN A;  4YPY A; 
#chains in the Genus database with same CATH homology
 4YPW A;  4YQ8 A;  1VHY A;  3ILK A;  3AXZ A;  4L69 A;  4YVH A;  4YQ7 A;  4YQJ A;  1MXI A;  2O3A A;  3O7B A;  3NK7 A;  4FAK A;  2EGV A;  3OIJ A;  1OY5 A;  3DCM X;  4YVG A;  4YQK A;  4JWG A;  4YQ5 A;  3IC6 A;  4YQT A;  1IPA A;  4YQP A;  4YQC A;  4YQ4 A;  2HA8 A;  4YQ3 A;  3BBD A;  4FMW A;  3N4K A;  4JWJ A;  4YVK A;  3N4J A;  4YQ2 A;  3OIN A;  4YQ6 A;  1J85 A;  4J3C A;  4X3L A;  4YQA A;  1NXZ A;  3BBH A;  5GMC A;  1P9P A;  3L8U A;  1UAJ A;  4MCC A;  4CND A;  4YQL A;  4YQG A;  3BBE A;  1UAL A;  1K3R A;  1VH0 A;  1TO0 A;  1UAM A;  4IG6 A;  1GZ0 A;  4JWH A;  4MCD A;  4YQN A;  3GYQ A;  4YPX A;  2I6D A;  4YQI A;  1O6D A;  1UAK A;  1V6Z A;  4CNF A;  4YQR A;  1X7P A;  5FAI A;  3AI9 X;  2Z0Y A;  5CO4 A;  4JAL A;  3ONP A;  3NK6 A;  1NS5 A;  4YPZ A;  4JAK A;  4YVI A;  4YQD A;  4YVJ A;  4XBO A;  2CX8 A;  3IEF A;  3QUV A;  5GM8 A;  4YQ1 A;  1X7O A;  1V2X A;  4H3Z A;  5GMB A;  4X3M A;  4E8B A;  4YQO A;  3OII A;  1VHK A;  2V3K A;  3KNU A;  4RG1 A;  4CNG A;  4YQ9 A;  3KW2 A;  2QMM A;  3E5Y A;  2EGW A;  3KY7 A;  4KDZ A;  4YQS A;  2YY8 A;  4YQQ A;  2V3J A;  1Z85 A;  3KTY A;  4YQ0 A;  4H3Y A;  1ZJR A;  3AIA A;  4PZK A;  4JWF A;  2QWV A;  4MCB A;  4YQB A;  5D9F A;  4CNE A;  4KGN A;  4YPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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