4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
source organism Escherichia coli
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
5GMBA 5GM8A 1VH0A 3IEFA 4PZKA 1GZ0A 1NS5A 4YVIA 3BBDA 1VHYA 4FAKA 4YVGA 1P9PA 3KTYA 4YQJA 4YQ5A 3ILKA 4XBOA 1V6ZA 4YQCA 4YQ2A 2EGWA 4MCCA 4JALA 4YPZA 1UAKA 3IC6A 4YQBA 4YQ9A 4YVHA 4YQSA 3KY7A 4YVJA 2YY8A 2NWAA 1TO0A 4MCBA 3BBEA 4YPYA 3KW2A 1K3RA 4YQAA 4YQTA 4YPXA 1UAMA 1NXZA 4YQLA 4L69A 3GYQA 4MCDA 3NK7A 3NK6A 1MXIA 3AIAA 4CNDA 3E5YA 4YQIA 3O7BA 3AXZA 4YQ8A 4X3LA 4KDZA 5D9FA 4YQ3A 1ZJRA 4YQPA 1UAJA 4YQ0A 1OY5A 4YQNA 4H3ZA 3L8UA 4YPWA 2EGVA 4YQ4A 2QMMA 3AI9X 5CO4A 4RG1A 1VHKA 4CNGA 3BBHA 4YQRA 1Z85A 3OIIA 3ONPA 4YQKA 4YQQA 1V2XA 2V3KA 4JAKA 3KNUA 4YQGA 1IPAA 2I6DA 2V3JA 3N4KA 1UALA 4E8BA 4X3MA 4YQDA 1J85A 4YQ6A 2O3AA 4YQOA 1X7PA 2QWVA 4CNFA 4IG6A 2CX8A 2HA8A 4J3CA 4YQ1A 4KGNA 3OINA 4CNEA 2Z0YA 4YVKA 1X7OA 3N4JA 3OIJA 1O6DA 3QUVA 5GMCA 4YQ7A 3DCMX 4H3YA 5FAIA
chains in the Genus database with same CATH superfamily
1O0BA 1GTSA 5GMBA 5GM8A 1VH0A 1QTQA 3IEFA 1O0CA 4IOAS 1GTRA 3X1LB 5BNZA 4PZKA 1GZ0A 4JWFA 1NS5A 3CZBA 4YVIA 3BBDA 1VHYA 4FAKA 4YVGA 1P9PA 3KTYA 4YQJA 4YQ5A 3ILKA 1B75A 4XBOA 1V6ZA 4YQCA 4YQ2A 2EGWA 4MCCA 4JALA 4YPZA 1UAKA 2GAEA 3IC6A 4YQBA 4WFNS 4YQ9A 4YVHA 4YQSA 5GAGW 3KY7A 4YVJA 1D6KA 2G5DA 2YY8A 4UY88 2NWAA 1TO0A 4JWHA 4MCBA 3BBEA 4YPYA 3KW2A 3W2WB 1K3RA 4YQAA 4YQTA 2AE0X 1UAMA 3DLLS 4YPXA 1NXZA 4YQLA 4L69A 3GYQA 2ZJQS 3NK7A 4MCDA 4IO9S 1UDXA 4U67S 3NK6A 1MXIA 3AIAA 4WF9S 2RD2A 4CNDA 3E5YA 4YQIA 3O7BA 4JXZA 1EUYA 3AXZA 5JVGS 4YQ8A 5GAHW 5GAEW 3J7ZV 2ZJRS 1EXDA 4KDZA 4X3LA 5D9FA 4YQ3A 1QRUA 1ZJRA 4H3SA 4JXXA 2PNWA 4YQPA 1UAJA 4JWJA 4FMWA 4IOCS 4YQ0A 1OY5A 4YQNA 5JVHS 3W2VB 4H3ZA 5IZNA 3L8UA 4YPWA 2EGVA 4YQ4A 2QMMA 3AI9X 1EUQA 1ZJWA 5CO4A 4RG1A 4WCES 3CF5S 1VHKA 4CNGA 2ZJPS 3BBHA 4V194 4YQRA 1Z85A 3PIPS 4WFAS 3OIIA 5HL7S 3ONPA 4H4KA 4YQKA 3PIOS 4YQQA 5GADW 1V2XA 4P2BA 2V3KA 4JAKA 3KNUA 4YQGA 1DFUP 2PICA 1IPAA 2I6DA 2V3JA 3N4KA 5DM7S 4E8BA 1UALA 4X3MA 1FEUA 1J85A 4YQDA 4YQ6A 2PI8A 2RE8A 2O3AA 4YQOA 1X7PA 2QWVA 4JWGA 4CNFA 4WFBS 1QRTA 2HZ7A 4IG6A 2CX8A 2HA8A 4J3CA 1QRSA 4KGNA 4YQ1A 4CNEA 3OINA 2Z0YA 4YVKA 1X7OA 5DM6S 2G6GA 3N4JA 3OIJA 1O6DA 2PJJA 3AIIA 3QUVA 5GMCA 4YQ7A 3DCMX 4H3YA 5FAIA 4JYZA 1NYLA
chains in the Genus database with same CATH topology
5GMBA 5GM8A 1VH0A 3IEFA 4PZKA 1GZ0A 4JWFA 1NS5A 4YVIA 3BBDA 1VHYA 4FAKA 4YVGA 1P9PA 3KTYA 4YQJA 4YQ5A 3ILKA 4XBOA 1V6ZA 4YQCA 4YQ2A 2EGWA 4MCCA 4JALA 4YPZA 1UAKA 3IC6A 4YQBA 4YQ9A 4YVHA 4YQSA 3KY7A 4YVJA 2YY8A 2NWAA 1TO0A 4JWHA 4MCBA 3BBEA 4YPYA 3KW2A 1K3RA 4YQAA 4YQTA 4YPXA 1UAMA 1NXZA 4YQLA 4L69A 3GYQA 4MCDA 3NK7A 3NK6A 1MXIA 3AIAA 4CNDA 3E5YA 4YQIA 3O7BA 3AXZA 4YQ8A 4X3LA 4KDZA 5D9FA 4YQ3A 1ZJRA 4YQPA 1UAJA 4JWJA 4FMWA 4YQ0A 1OY5A 4YQNA 4H3ZA 3L8UA 4YPWA 2EGVA 4YQ4A 2QMMA 3AI9X 5CO4A 4RG1A 1VHKA 4CNGA 3BBHA 4YQRA 1Z85A 3OIIA 3ONPA 4YQKA 4YQQA 1V2XA 2V3KA 4JAKA 3KNUA 4YQGA 1IPAA 2I6DA 2V3JA 3N4KA 1UALA 4E8BA 4X3MA 4YQDA 1J85A 4YQ6A 2O3AA 4YQOA 1X7PA 2QWVA 4JWGA 4CNFA 4IG6A 2CX8A 2HA8A 4J3CA 4YQ1A 4KGNA 3OINA 4CNEA 2Z0YA 4YVKA 1X7OA 3N4JA 3OIJA 1O6DA 3QUVA 5GMCA 4YQ7A 3DCMX 4H3YA 5FAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GMB A;  5GM8 A;  1VH0 A;  3IEF A;  4PZK A;  1GZ0 A;  1NS5 A;  4YVI A;  3BBD A;  1VHY A;  4FAK A;  4YVG A;  1P9P A;  3KTY A;  4YQJ A;  4YQ5 A;  3ILK A;  4XBO A;  1V6Z A;  4YQC A;  4YQ2 A;  2EGW A;  4MCC A;  4JAL A;  4YPZ A;  1UAK A;  3IC6 A;  4YQB A;  4YQ9 A;  4YVH A;  4YQS A;  3KY7 A;  4YVJ A;  2YY8 A;  2NWA A;  1TO0 A;  4MCB A;  3BBE A;  4YPY A;  3KW2 A;  1K3R A;  4YQA A;  4YQT A;  4YPX A;  1UAM A;  1NXZ A;  4YQL A;  4L69 A;  3GYQ A;  4MCD A;  3NK7 A;  3NK6 A;  1MXI A;  3AIA A;  4CND A;  3E5Y A;  4YQI A;  3O7B A;  3AXZ A;  4YQ8 A;  4X3L A;  4KDZ A;  5D9F A;  4YQ3 A;  1ZJR A;  4YQP A;  1UAJ A;  4YQ0 A;  1OY5 A;  4YQN A;  4H3Z A;  3L8U A;  4YPW A;  2EGV A;  4YQ4 A;  2QMM A;  3AI9 X;  5CO4 A;  4RG1 A;  1VHK A;  4CNG A;  3BBH A;  4YQR A;  1Z85 A;  3OII A;  3ONP A;  4YQK A;  4YQQ A;  1V2X A;  2V3K A;  4JAK A;  3KNU A;  4YQG A;  1IPA A;  2I6D A;  2V3J A;  3N4K A;  1UAL A;  4E8B A;  4X3M A;  4YQD A;  1J85 A;  4YQ6 A;  2O3A A;  4YQO A;  1X7P A;  2QWV A;  4CNF A;  4IG6 A;  2CX8 A;  2HA8 A;  4J3C A;  4YQ1 A;  4KGN A;  3OIN A;  4CNE A;  2Z0Y A;  4YVK A;  1X7O A;  3N4J A;  3OIJ A;  1O6D A;  3QUV A;  5GMC A;  4YQ7 A;  3DCM X;  4H3Y A;  5FAI A; 
#chains in the Genus database with same CATH topology
 1O0B A;  1GTS A;  5GMB A;  5GM8 A;  1VH0 A;  1QTQ A;  3IEF A;  1O0C A;  4IOA S;  1GTR A;  3X1L B;  5BNZ A;  4PZK A;  1GZ0 A;  4JWF A;  1NS5 A;  3CZB A;  4YVI A;  3BBD A;  1VHY A;  4FAK A;  4YVG A;  1P9P A;  3KTY A;  4YQJ A;  4YQ5 A;  3ILK A;  1B75 A;  4XBO A;  1V6Z A;  4YQC A;  4YQ2 A;  2EGW A;  4MCC A;  4JAL A;  4YPZ A;  1UAK A;  2GAE A;  3IC6 A;  4YQB A;  4WFN S;  4YQ9 A;  4YVH A;  4YQS A;  5GAG W;  3KY7 A;  4YVJ A;  1D6K A;  2G5D A;  2YY8 A;  4UY8 8;  2NWA A;  1TO0 A;  4JWH A;  4MCB A;  3BBE A;  4YPY A;  3KW2 A;  3W2W B;  1K3R A;  4YQA A;  4YQT A;  2AE0 X;  1UAM A;  3DLL S;  4YPX A;  1NXZ A;  4YQL A;  4L69 A;  3GYQ A;  2ZJQ S;  3NK7 A;  4MCD A;  4IO9 S;  1UDX A;  4U67 S;  3NK6 A;  1MXI A;  3AIA A;  4WF9 S;  2RD2 A;  4CND A;  3E5Y A;  4YQI A;  3O7B A;  4JXZ A;  1EUY A;  3AXZ A;  5JVG S;  4YQ8 A;  5GAH W;  5GAE W;  3J7Z V;  2ZJR S;  1EXD A;  4KDZ A;  4X3L A;  5D9F A;  4YQ3 A;  1QRU A;  1ZJR A;  4H3S A;  4JXX A;  2PNW A;  4YQP A;  1UAJ A;  4JWJ A;  4FMW A;  4IOC S;  4YQ0 A;  1OY5 A;  4YQN A;  5JVH S;  3W2V B;  4H3Z A;  5IZN A;  3L8U A;  4YPW A;  2EGV A;  4YQ4 A;  2QMM A;  3AI9 X;  1EUQ A;  1ZJW A;  5CO4 A;  4RG1 A;  4WCE S;  3CF5 S;  1VHK A;  4CNG A;  2ZJP S;  3BBH A;  4V19 4;  4YQR A;  1Z85 A;  3PIP S;  4WFA S;  3OII A;  5HL7 S;  3ONP A;  4H4K A;  4YQK A;  3PIO S;  4YQQ A;  5GAD W;  1V2X A;  4P2B A;  2V3K A;  4JAK A;  3KNU A;  4YQG A;  1DFU P;  2PIC A;  1IPA A;  2I6D A;  2V3J A;  3N4K A;  5DM7 S;  4E8B A;  1UAL A;  4X3M A;  1FEU A;  1J85 A;  4YQD A;  4YQ6 A;  2PI8 A;  2RE8 A;  2O3A A;  4YQO A;  1X7P A;  2QWV A;  4JWG A;  4CNF A;  4WFB S;  1QRT A;  2HZ7 A;  4IG6 A;  2CX8 A;  2HA8 A;  4J3C A;  1QRS A;  4KGN A;  4YQ1 A;  4CNE A;  3OIN A;  2Z0Y A;  4YVK A;  1X7O A;  5DM6 S;  2G6G A;  3N4J A;  3OIJ A;  1O6D A;  2PJJ A;  3AII A;  3QUV A;  5GMC A;  4YQ7 A;  3DCM X;  4H3Y A;  5FAI A;  4JYZ A;  1NYL A; 
#chains in the Genus database with same CATH homology
 5GMB A;  5GM8 A;  1VH0 A;  3IEF A;  4PZK A;  1GZ0 A;  4JWF A;  1NS5 A;  4YVI A;  3BBD A;  1VHY A;  4FAK A;  4YVG A;  1P9P A;  3KTY A;  4YQJ A;  4YQ5 A;  3ILK A;  4XBO A;  1V6Z A;  4YQC A;  4YQ2 A;  2EGW A;  4MCC A;  4JAL A;  4YPZ A;  1UAK A;  3IC6 A;  4YQB A;  4YQ9 A;  4YVH A;  4YQS A;  3KY7 A;  4YVJ A;  2YY8 A;  2NWA A;  1TO0 A;  4JWH A;  4MCB A;  3BBE A;  4YPY A;  3KW2 A;  1K3R A;  4YQA A;  4YQT A;  4YPX A;  1UAM A;  1NXZ A;  4YQL A;  4L69 A;  3GYQ A;  4MCD A;  3NK7 A;  3NK6 A;  1MXI A;  3AIA A;  4CND A;  3E5Y A;  4YQI A;  3O7B A;  3AXZ A;  4YQ8 A;  4X3L A;  4KDZ A;  5D9F A;  4YQ3 A;  1ZJR A;  4YQP A;  1UAJ A;  4JWJ A;  4FMW A;  4YQ0 A;  1OY5 A;  4YQN A;  4H3Z A;  3L8U A;  4YPW A;  2EGV A;  4YQ4 A;  2QMM A;  3AI9 X;  5CO4 A;  4RG1 A;  1VHK A;  4CNG A;  3BBH A;  4YQR A;  1Z85 A;  3OII A;  3ONP A;  4YQK A;  4YQQ A;  1V2X A;  2V3K A;  4JAK A;  3KNU A;  4YQG A;  1IPA A;  2I6D A;  2V3J A;  3N4K A;  1UAL A;  4E8B A;  4X3M A;  4YQD A;  1J85 A;  4YQ6 A;  2O3A A;  4YQO A;  1X7P A;  2QWV A;  4JWG A;  4CNF A;  4IG6 A;  2CX8 A;  2HA8 A;  4J3C A;  4YQ1 A;  4KGN A;  3OIN A;  4CNE A;  2Z0Y A;  4YVK A;  1X7O A;  3N4J A;  3OIJ A;  1O6D A;  3QUV A;  5GMC A;  4YQ7 A;  3DCM X;  4H3Y A;  5FAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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