4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
4YVGA 4YQAA 3O7BA 1V6ZA 3IEFA 3DCMX 4J3CA 3AXZA 3OIJA 4YQ5A 2QMMA 4YQDA 2NWAA 4YQ1A 4YQRA 4YPXA 2EGVA 1P9PA 1X7OA 3E5YA 2YY8A 4YPYA 3KTYA 4JAKA 4XBOA 2O3AA 3L8UA 4YQ0A 1VH0A 1VHYA 4RG1A 3AIAA 4CNFA 4CNDA 5FAIA 4E8BA 4YPZA 2V3JA 1K3RA 4YPWA 2V3KA 1MXIA 1NS5A 3KNUA 4MCDA 4YQ9A 4YQ4A 4CNGA 1IPAA 2Z0YA 3ONPA 4CNEA 4IG6A 4PZKA 3NK7A 4KDZA 4YVKA 3N4KA 2HA8A 4H3YA 2I6DA 4YQ2A 3BBEA 4YQ7A 1GZ0A 3GYQA 4YVHA 1UAJA 4H3ZA 4KGNA 5CO4A 3AI9X 1O6DA 4YQQA 4YQOA 4YQCA 5GMBA 1VHKA 3ILKA 5GMCA 4YQ3A 4YQ6A 3BBHA 3QUVA 4YQ8A 4YQIA 4YQJA 4YQNA 3BBDA 4MCBA 4YVJA 4YQTA 4YQLA 3OIIA 4MCCA 4YQKA 3IC6A 4YQPA 4X3LA 4YQSA 3OINA 1J85A 1X7PA 4FAKA 5D9FA 1V2XA 4YVIA 2CX8A 4JALA 1TO0A 3N4JA 3KY7A 4YQBA 1OY5A 2QWVA 2EGWA 1UALA 5GM8A 1NXZA 4YQGA 1ZJRA 3KW2A 1UAMA 3NK6A 4X3MA 1UAKA 1Z85A 4L69A
chains in the Genus database with same CATH superfamily
4YVGA 2RD2A 4YQAA 4WFAS 3O7BA 1V6ZA 3IEFA 3DCMX 4J3CA 3AXZA 4U67S 4JYZA 4YQ5A 2QMMA 3OIJA 4YQDA 2NWAA 4YQ1A 4YQRA 4YPXA 1O0CA 4UY88 3DLLS 2EGVA 1P9PA 1X7OA 3E5YA 2YY8A 4YPYA 2ZJQS 3KTYA 4JAKA 4XBOA 2O3AA 3L8UA 3PIPS 1GTRA 4YQ0A 1VH0A 1VHYA 5DM7S 4IOCS 4JWHA 4RG1A 3AIAA 1EUQA 4CNFA 4CNDA 1GTSA 4H4KA 1NYLA 5FAIA 4E8BA 4YPZA 2V3JA 1K3RA 4YPWA 4WFNS 3AIIA 2V3KA 1MXIA 1NS5A 3KNUA 1ZJWA 4MCDA 4YQ9A 4YQ4A 1QRTA 4CNGA 1IPAA 4WFBS 3PIOS 2PICA 2Z0YA 5GAHW 5IZNA 1QRUA 3ONPA 2GAEA 5GAGW 4CNEA 4IG6A 4PZKA 2G6GA 3CF5S 3NK7A 4KDZA 4YVKA 4JWFA 3N4KA 2HA8A 4H3YA 2I6DA 4YQ2A 4JWGA 3BBEA 4YQ7A 1GZ0A 1UDXA 3GYQA 1D6KA 4YVHA 1UAJA 4H3ZA 4KGNA 4IOAS 5CO4A 3AI9X 4JWJA 1O6DA 4YQQA 2ZJRS 1FEUA 4YQOA 1QRSA 4YQCA 5GAEW 2ZJPS 4FMWA 5JVGS 5GMBA 1VHKA 5BNZA 3ILKA 3CZBA 5GMCA 4YQ3A 2HZ7A 2PI8A 4YQ6A 3BBHA 3QUVA 4YQ8A 4YQIA 4YQJA 4YQNA 3BBDA 4P2BA 4MCBA 4YVJA 4H3SA 4YQTA 4YQLA 3OIIA 4MCCA 4YQKA 4WCES 3IC6A 2AE0X 3W2VB 3J7ZV 4YQPA 4V194 4X3LA 1QTQA 4JXZA 4YQSA 3OINA 1J85A 1X7PA 4FAKA 5D9FA 2PNWA 1V2XA 4YVIA 2G5DA 1EUYA 5HL7S 2PJJA 2CX8A 5DM6S 5JVHS 4IO9S 1TO0A 3N4JA 3KY7A 4JALA 4JXXA 4WF9S 3X1LB 1OY5A 1DFUP 2QWVA 4YQBA 2EGWA 1UALA 5GM8A 3W2WB 1NXZA 1B75A 4YQGA 1EXDA 1ZJRA 3KW2A 1O0BA 1UAMA 5GADW 2RE8A 3NK6A 4X3MA 1UAKA 1Z85A 4L69A
chains in the Genus database with same CATH topology
4YVGA 4YQAA 3O7BA 1V6ZA 3IEFA 3DCMX 4J3CA 3AXZA 3OIJA 4YQ5A 2QMMA 4YQDA 2NWAA 4YQ1A 4YQRA 4YPXA 2EGVA 1P9PA 1X7OA 3E5YA 2YY8A 4YPYA 3KTYA 4JAKA 4XBOA 2O3AA 3L8UA 4YQ0A 1VH0A 1VHYA 4JWHA 4RG1A 3AIAA 4CNFA 4CNDA 5FAIA 4E8BA 4YPZA 2V3JA 1K3RA 4YPWA 2V3KA 1MXIA 1NS5A 3KNUA 4MCDA 4YQ9A 4YQ4A 4CNGA 1IPAA 2Z0YA 3ONPA 4CNEA 4IG6A 4PZKA 3NK7A 4KDZA 4YVKA 4JWFA 3N4KA 2HA8A 4H3YA 2I6DA 4YQ2A 4JWGA 3BBEA 4YQ7A 1GZ0A 3GYQA 4YVHA 1UAJA 4H3ZA 4KGNA 5CO4A 3AI9X 4JWJA 1O6DA 4YQQA 4YQOA 4YQCA 4FMWA 5GMBA 1VHKA 3ILKA 5GMCA 4YQ3A 4YQ6A 3BBHA 3QUVA 4YQ8A 4YQIA 4YQJA 4YQNA 3BBDA 4MCBA 4YVJA 4YQTA 4YQLA 3OIIA 4MCCA 4YQKA 3IC6A 4YQPA 4X3LA 4YQSA 3OINA 1J85A 1X7PA 4FAKA 5D9FA 1V2XA 4YVIA 2CX8A 4JALA 1TO0A 3N4JA 3KY7A 4YQBA 1OY5A 2QWVA 2EGWA 1UALA 5GM8A 1NXZA 4YQGA 1ZJRA 3KW2A 1UAMA 3NK6A 4X3MA 1UAKA 1Z85A 4L69A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVG A;  4YQA A;  3O7B A;  1V6Z A;  3IEF A;  3DCM X;  4J3C A;  3AXZ A;  3OIJ A;  4YQ5 A;  2QMM A;  4YQD A;  2NWA A;  4YQ1 A;  4YQR A;  4YPX A;  2EGV A;  1P9P A;  1X7O A;  3E5Y A;  2YY8 A;  4YPY A;  3KTY A;  4JAK A;  4XBO A;  2O3A A;  3L8U A;  4YQ0 A;  1VH0 A;  1VHY A;  4RG1 A;  3AIA A;  4CNF A;  4CND A;  5FAI A;  4E8B A;  4YPZ A;  2V3J A;  1K3R A;  4YPW A;  2V3K A;  1MXI A;  1NS5 A;  3KNU A;  4MCD A;  4YQ9 A;  4YQ4 A;  4CNG A;  1IPA A;  2Z0Y A;  3ONP A;  4CNE A;  4IG6 A;  4PZK A;  3NK7 A;  4KDZ A;  4YVK A;  3N4K A;  2HA8 A;  4H3Y A;  2I6D A;  4YQ2 A;  3BBE A;  4YQ7 A;  1GZ0 A;  3GYQ A;  4YVH A;  1UAJ A;  4H3Z A;  4KGN A;  5CO4 A;  3AI9 X;  1O6D A;  4YQQ A;  4YQO A;  4YQC A;  5GMB A;  1VHK A;  3ILK A;  5GMC A;  4YQ3 A;  4YQ6 A;  3BBH A;  3QUV A;  4YQ8 A;  4YQI A;  4YQJ A;  4YQN A;  3BBD A;  4MCB A;  4YVJ A;  4YQT A;  4YQL A;  3OII A;  4MCC A;  4YQK A;  3IC6 A;  4YQP A;  4X3L A;  4YQS A;  3OIN A;  1J85 A;  1X7P A;  4FAK A;  5D9F A;  1V2X A;  4YVI A;  2CX8 A;  4JAL A;  1TO0 A;  3N4J A;  3KY7 A;  4YQB A;  1OY5 A;  2QWV A;  2EGW A;  1UAL A;  5GM8 A;  1NXZ A;  4YQG A;  1ZJR A;  3KW2 A;  1UAM A;  3NK6 A;  4X3M A;  1UAK A;  1Z85 A;  4L69 A; 
#chains in the Genus database with same CATH topology
 4YVG A;  2RD2 A;  4YQA A;  4WFA S;  3O7B A;  1V6Z A;  3IEF A;  3DCM X;  4J3C A;  3AXZ A;  4U67 S;  4JYZ A;  4YQ5 A;  2QMM A;  3OIJ A;  4YQD A;  2NWA A;  4YQ1 A;  4YQR A;  4YPX A;  1O0C A;  4UY8 8;  3DLL S;  2EGV A;  1P9P A;  1X7O A;  3E5Y A;  2YY8 A;  4YPY A;  2ZJQ S;  3KTY A;  4JAK A;  4XBO A;  2O3A A;  3L8U A;  3PIP S;  1GTR A;  4YQ0 A;  1VH0 A;  1VHY A;  5DM7 S;  4IOC S;  4JWH A;  4RG1 A;  3AIA A;  1EUQ A;  4CNF A;  4CND A;  1GTS A;  4H4K A;  1NYL A;  5FAI A;  4E8B A;  4YPZ A;  2V3J A;  1K3R A;  4YPW A;  4WFN S;  3AII A;  2V3K A;  1MXI A;  1NS5 A;  3KNU A;  1ZJW A;  4MCD A;  4YQ9 A;  4YQ4 A;  1QRT A;  4CNG A;  1IPA A;  4WFB S;  3PIO S;  2PIC A;  2Z0Y A;  5GAH W;  5IZN A;  1QRU A;  3ONP A;  2GAE A;  5GAG W;  4CNE A;  4IG6 A;  4PZK A;  2G6G A;  3CF5 S;  3NK7 A;  4KDZ A;  4YVK A;  4JWF A;  3N4K A;  2HA8 A;  4H3Y A;  2I6D A;  4YQ2 A;  4JWG A;  3BBE A;  4YQ7 A;  1GZ0 A;  1UDX A;  3GYQ A;  1D6K A;  4YVH A;  1UAJ A;  4H3Z A;  4KGN A;  4IOA S;  5CO4 A;  3AI9 X;  4JWJ A;  1O6D A;  4YQQ A;  2ZJR S;  1FEU A;  4YQO A;  1QRS A;  4YQC A;  5GAE W;  2ZJP S;  4FMW A;  5JVG S;  5GMB A;  1VHK A;  5BNZ A;  3ILK A;  3CZB A;  5GMC A;  4YQ3 A;  2HZ7 A;  2PI8 A;  4YQ6 A;  3BBH A;  3QUV A;  4YQ8 A;  4YQI A;  4YQJ A;  4YQN A;  3BBD A;  4P2B A;  4MCB A;  4YVJ A;  4H3S A;  4YQT A;  4YQL A;  3OII A;  4MCC A;  4YQK A;  4WCE S;  3IC6 A;  2AE0 X;  3W2V B;  3J7Z V;  4YQP A;  4V19 4;  4X3L A;  1QTQ A;  4JXZ A;  4YQS A;  3OIN A;  1J85 A;  1X7P A;  4FAK A;  5D9F A;  2PNW A;  1V2X A;  4YVI A;  2G5D A;  1EUY A;  5HL7 S;  2PJJ A;  2CX8 A;  5DM6 S;  5JVH S;  4IO9 S;  1TO0 A;  3N4J A;  3KY7 A;  4JAL A;  4JXX A;  4WF9 S;  3X1L B;  1OY5 A;  1DFU P;  2QWV A;  4YQB A;  2EGW A;  1UAL A;  5GM8 A;  3W2W B;  1NXZ A;  1B75 A;  4YQG A;  1EXD A;  1ZJR A;  3KW2 A;  1O0B A;  1UAM A;  5GAD W;  2RE8 A;  3NK6 A;  4X3M A;  1UAK A;  1Z85 A;  4L69 A; 
#chains in the Genus database with same CATH homology
 4YVG A;  4YQA A;  3O7B A;  1V6Z A;  3IEF A;  3DCM X;  4J3C A;  3AXZ A;  3OIJ A;  4YQ5 A;  2QMM A;  4YQD A;  2NWA A;  4YQ1 A;  4YQR A;  4YPX A;  2EGV A;  1P9P A;  1X7O A;  3E5Y A;  2YY8 A;  4YPY A;  3KTY A;  4JAK A;  4XBO A;  2O3A A;  3L8U A;  4YQ0 A;  1VH0 A;  1VHY A;  4JWH A;  4RG1 A;  3AIA A;  4CNF A;  4CND A;  5FAI A;  4E8B A;  4YPZ A;  2V3J A;  1K3R A;  4YPW A;  2V3K A;  1MXI A;  1NS5 A;  3KNU A;  4MCD A;  4YQ9 A;  4YQ4 A;  4CNG A;  1IPA A;  2Z0Y A;  3ONP A;  4CNE A;  4IG6 A;  4PZK A;  3NK7 A;  4KDZ A;  4YVK A;  4JWF A;  3N4K A;  2HA8 A;  4H3Y A;  2I6D A;  4YQ2 A;  4JWG A;  3BBE A;  4YQ7 A;  1GZ0 A;  3GYQ A;  4YVH A;  1UAJ A;  4H3Z A;  4KGN A;  5CO4 A;  3AI9 X;  4JWJ A;  1O6D A;  4YQQ A;  4YQO A;  4YQC A;  4FMW A;  5GMB A;  1VHK A;  3ILK A;  5GMC A;  4YQ3 A;  4YQ6 A;  3BBH A;  3QUV A;  4YQ8 A;  4YQI A;  4YQJ A;  4YQN A;  3BBD A;  4MCB A;  4YVJ A;  4YQT A;  4YQL A;  3OII A;  4MCC A;  4YQK A;  3IC6 A;  4YQP A;  4X3L A;  4YQS A;  3OIN A;  1J85 A;  1X7P A;  4FAK A;  5D9F A;  1V2X A;  4YVI A;  2CX8 A;  4JAL A;  1TO0 A;  3N4J A;  3KY7 A;  4YQB A;  1OY5 A;  2QWV A;  2EGW A;  1UAL A;  5GM8 A;  1NXZ A;  4YQG A;  1ZJR A;  3KW2 A;  1UAM A;  3NK6 A;  4X3M A;  1UAK A;  1Z85 A;  4L69 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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