4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
b'IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
2V3KA 4YQKA 3BBDA 2YY8A 2O3AA 1IPAA 3BBEA 4YPYA 3N4JA 3E5YA 4IG6A 1NS5A 1UAMA 3OINA 2EGVA 1TO0A 4KGNA 4YQ3A 3NK6A 3KTYA 4X3MA 4CNFA 4YQJA 2QWVA 4YPZA 4YVKA 1Z85A 4XBOA 4YQ5A 1ZJRA 4YQOA 4YQTA 4FAKA 1V2XA 4YQQA 4YPWA 4E8BA 2EGWA 3AI9X 4YQLA 4CNGA 3N4KA 4YQ8A 4YQ1A 4YVHA 1VHYA 4PZKA 3ONPA 4YQDA 3KNUA 4JAKA 5FAIA 5D9FA 2I6DA 4RG1A 3IEFA 1UAJA 1VH0A 4YQRA 2HA8A 4KDZA 3AIAA 3NK7A 4CNDA 4J3CA 5GMCA 4YQGA 4YVJA 4X3LA 3QUVA 3OIIA 1X7PA 4YQIA 4YQ6A 1MXIA 4MCDA 4YQ9A 3DCMX 3L8UA 3ILKA 1GZ0A 4JALA 3BBHA 3OIJA 4YQSA 3AXZA 5CO4A 1OY5A 3IC6A 3KY7A 4H3ZA 3KW2A 3O7BA 1X7OA 3GYQA 4YQCA 4MCBA 5GM8A 4YQBA 2NWAA 1UAKA 4CNEA 4MCCA 1O6DA 4YQAA 1NXZA 2QMMA 1V6ZA 4YPXA 4YQ7A 4YVIA 4L69A 2V3JA 2Z0YA 4YQNA 4YQPA 4H3YA 4YQ0A 5GMBA 4YQ4A 2CX8A 1P9PA 1J85A 4YVGA 4YQ2A 1K3RA 1UALA 1VHKA
chains in the Genus database with same CATH superfamily
2V3KA 4YQKA 3BBDA 2YY8A 4IOCS 2O3AA 1IPAA 3BBEA 1QRTA 4H4KA 5GAEW 4YPYA 3N4JA 3E5YA 4IG6A 1NS5A 1UAMA 2PI8A 3OINA 2EGVA 1TO0A 4KGNA 4YQ3A 1B75A 3DLLS 5GAGW 3NK6A 2HZ7A 3KTYA 4X3MA 4CNFA 1NYLA 4YQJA 2QWVA 4YPZA 2GAEA 4WF9S 4YVKA 1Z85A 4XBOA 4YQ5A 3AIIA 1ZJWA 1ZJRA 4YQOA 4YQTA 4FAKA 1V2XA 4YQQA 1O0CA 5DM7S 4YPWA 4E8BA 2EGWA 5HL7S 3AI9X 4YQLA 1GTSA 3N4KA 4YQ8A 4CNGA 4YQ1A 4YVHA 4IOAS 1VHYA 5JVGS 4PZKA 3ONPA 4YQDA 3KNUA 2RE8A 4JAKA 1EXDA 5FAIA 1DFUP 5D9FA 2I6DA 4RG1A 1O0BA 4JWHA 5IZNA 1EUYA 4IO9S 3W2VB 3IEFA 1UAJA 1VH0A 4YQRA 2HA8A 4KDZA 2G6GA 3AIAA 4JWGA 3W2WB 3CF5S 3NK7A 4CNDA 4J3CA 5GADW 5GMCA 4CNEA 4JXXA 4X3LA 4YQGA 4YVJA 3QUVA 3OIIA 4WCES 1X7PA 4YQIA 3J7ZV 2AE0X 4WFAS 4YQ6A 2PJJA 1MXIA 4MCDA 2PICA 2PNWA 4YQ9A 3CZBA 3DCMX 3L8UA 3ILKA 1GZ0A 4JALA 5GAHW 3BBHA 3OIJA 1GTRA 4YQSA 3AXZA 5CO4A 1OY5A 3IC6A 4JWFA 2RD2A 3KY7A 4H3ZA 1UDXA 5DM6S 3KW2A 3O7BA 1X7OA 4JYZA 4U67S 3GYQA 4YQCA 4MCBA 5GM8A 4YQBA 5JVHS 1FEUA 2NWAA 1UAKA 4FMWA 4MCCA 1O6DA 2ZJPS 2ZJRS 1NXZA 1QTQA 3PIPS 2QMMA 4YQAA 1V6ZA 4YPXA 4WFBS 4YQ7A 4V194 1QRUA 5BNZA 4UY88 4JXZA 4YVIA 4L69A 2V3JA 2Z0YA 4YQNA 3PIOS 4YQPA 1D6KA 3X1LB 4H3YA 2G5DA 4YQ0A 4P2BA 5GMBA 4YQ4A 4WFNS 2ZJQS 2CX8A 1P9PA 1J85A 4YVGA 4H3SA 4JWJA 4YQ2A 1K3RA 1QRSA 1UALA 1EUQA 1VHKA
chains in the Genus database with same CATH topology
2V3KA 4YQKA 3BBDA 2YY8A 2O3AA 1IPAA 3BBEA 4YPYA 3N4JA 3E5YA 4IG6A 1NS5A 1UAMA 3OINA 2EGVA 1TO0A 4KGNA 4YQ3A 3NK6A 3KTYA 4X3MA 4CNFA 4YQJA 2QWVA 4YPZA 4YVKA 1Z85A 4XBOA 4YQ5A 1ZJRA 4YQOA 4YQTA 4FAKA 1V2XA 4YQQA 4YPWA 4E8BA 2EGWA 3AI9X 4YQLA 4CNGA 3N4KA 4YQ8A 4YQ1A 4YVHA 1VHYA 4PZKA 3ONPA 4YQDA 3KNUA 4JAKA 5FAIA 5D9FA 2I6DA 4RG1A 4JWHA 3IEFA 1UAJA 1VH0A 4YQRA 2HA8A 4KDZA 3AIAA 4JWGA 3NK7A 4CNDA 4J3CA 5GMCA 4YQGA 4YVJA 4X3LA 3QUVA 3OIIA 1X7PA 4YQIA 4YQ6A 1MXIA 4MCDA 4YQ9A 3DCMX 3L8UA 3ILKA 1GZ0A 4JALA 3BBHA 3OIJA 4YQSA 3AXZA 5CO4A 1OY5A 3IC6A 4JWFA 3KY7A 4H3ZA 3KW2A 3O7BA 1X7OA 3GYQA 4YQCA 4MCBA 5GM8A 4YQBA 2NWAA 1UAKA 4FMWA 4MCCA 1O6DA 4CNEA 4YQAA 1NXZA 2QMMA 1V6ZA 4YPXA 4YQ7A 4YVIA 4L69A 2V3JA 2Z0YA 4YQNA 4YQPA 4H3YA 4YQ0A 5GMBA 4YQ4A 2CX8A 1P9PA 1J85A 4YVGA 4JWJA 4YQ2A 1K3RA 1UALA 1VHKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V3K A;  4YQK A;  3BBD A;  2YY8 A;  2O3A A;  1IPA A;  3BBE A;  4YPY A;  3N4J A;  3E5Y A;  4IG6 A;  1NS5 A;  1UAM A;  3OIN A;  2EGV A;  1TO0 A;  4KGN A;  4YQ3 A;  3NK6 A;  3KTY A;  4X3M A;  4CNF A;  4YQJ A;  2QWV A;  4YPZ A;  4YVK A;  1Z85 A;  4XBO A;  4YQ5 A;  1ZJR A;  4YQO A;  4YQT A;  4FAK A;  1V2X A;  4YQQ A;  4YPW A;  4E8B A;  2EGW A;  3AI9 X;  4YQL A;  4CNG A;  3N4K A;  4YQ8 A;  4YQ1 A;  4YVH A;  1VHY A;  4PZK A;  3ONP A;  4YQD A;  3KNU A;  4JAK A;  5FAI A;  5D9F A;  2I6D A;  4RG1 A;  3IEF A;  1UAJ A;  1VH0 A;  4YQR A;  2HA8 A;  4KDZ A;  3AIA A;  3NK7 A;  4CND A;  4J3C A;  5GMC A;  4YQG A;  4YVJ A;  4X3L A;  3QUV A;  3OII A;  1X7P A;  4YQI A;  4YQ6 A;  1MXI A;  4MCD A;  4YQ9 A;  3DCM X;  3L8U A;  3ILK A;  1GZ0 A;  4JAL A;  3BBH A;  3OIJ A;  4YQS A;  3AXZ A;  5CO4 A;  1OY5 A;  3IC6 A;  3KY7 A;  4H3Z A;  3KW2 A;  3O7B A;  1X7O A;  3GYQ A;  4YQC A;  4MCB A;  5GM8 A;  4YQB A;  2NWA A;  1UAK A;  4CNE A;  4MCC A;  1O6D A;  4YQA A;  1NXZ A;  2QMM A;  1V6Z A;  4YPX A;  4YQ7 A;  4YVI A;  4L69 A;  2V3J A;  2Z0Y A;  4YQN A;  4YQP A;  4H3Y A;  4YQ0 A;  5GMB A;  4YQ4 A;  2CX8 A;  1P9P A;  1J85 A;  4YVG A;  4YQ2 A;  1K3R A;  1UAL A;  1VHK A; 
#chains in the Genus database with same CATH topology
 2V3K A;  4YQK A;  3BBD A;  2YY8 A;  4IOC S;  2O3A A;  1IPA A;  3BBE A;  1QRT A;  4H4K A;  5GAE W;  4YPY A;  3N4J A;  3E5Y A;  4IG6 A;  1NS5 A;  1UAM A;  2PI8 A;  3OIN A;  2EGV A;  1TO0 A;  4KGN A;  4YQ3 A;  1B75 A;  3DLL S;  5GAG W;  3NK6 A;  2HZ7 A;  3KTY A;  4X3M A;  4CNF A;  1NYL A;  4YQJ A;  2QWV A;  4YPZ A;  2GAE A;  4WF9 S;  4YVK A;  1Z85 A;  4XBO A;  4YQ5 A;  3AII A;  1ZJW A;  1ZJR A;  4YQO A;  4YQT A;  4FAK A;  1V2X A;  4YQQ A;  1O0C A;  5DM7 S;  4YPW A;  4E8B A;  2EGW A;  5HL7 S;  3AI9 X;  4YQL A;  1GTS A;  3N4K A;  4YQ8 A;  4CNG A;  4YQ1 A;  4YVH A;  4IOA S;  1VHY A;  5JVG S;  4PZK A;  3ONP A;  4YQD A;  3KNU A;  2RE8 A;  4JAK A;  1EXD A;  5FAI A;  1DFU P;  5D9F A;  2I6D A;  4RG1 A;  1O0B A;  4JWH A;  5IZN A;  1EUY A;  4IO9 S;  3W2V B;  3IEF A;  1UAJ A;  1VH0 A;  4YQR A;  2HA8 A;  4KDZ A;  2G6G A;  3AIA A;  4JWG A;  3W2W B;  3CF5 S;  3NK7 A;  4CND A;  4J3C A;  5GAD W;  5GMC A;  4CNE A;  4JXX A;  4X3L A;  4YQG A;  4YVJ A;  3QUV A;  3OII A;  4WCE S;  1X7P A;  4YQI A;  3J7Z V;  2AE0 X;  4WFA S;  4YQ6 A;  2PJJ A;  1MXI A;  4MCD A;  2PIC A;  2PNW A;  4YQ9 A;  3CZB A;  3DCM X;  3L8U A;  3ILK A;  1GZ0 A;  4JAL A;  5GAH W;  3BBH A;  3OIJ A;  1GTR A;  4YQS A;  3AXZ A;  5CO4 A;  1OY5 A;  3IC6 A;  4JWF A;  2RD2 A;  3KY7 A;  4H3Z A;  1UDX A;  5DM6 S;  3KW2 A;  3O7B A;  1X7O A;  4JYZ A;  4U67 S;  3GYQ A;  4YQC A;  4MCB A;  5GM8 A;  4YQB A;  5JVH S;  1FEU A;  2NWA A;  1UAK A;  4FMW A;  4MCC A;  1O6D A;  2ZJP S;  2ZJR S;  1NXZ A;  1QTQ A;  3PIP S;  2QMM A;  4YQA A;  1V6Z A;  4YPX A;  4WFB S;  4YQ7 A;  4V19 4;  1QRU A;  5BNZ A;  4UY8 8;  4JXZ A;  4YVI A;  4L69 A;  2V3J A;  2Z0Y A;  4YQN A;  3PIO S;  4YQP A;  1D6K A;  3X1L B;  4H3Y A;  2G5D A;  4YQ0 A;  4P2B A;  5GMB A;  4YQ4 A;  4WFN S;  2ZJQ S;  2CX8 A;  1P9P A;  1J85 A;  4YVG A;  4H3S A;  4JWJ A;  4YQ2 A;  1K3R A;  1QRS A;  1UAL A;  1EUQ A;  1VHK A; 
#chains in the Genus database with same CATH homology
 2V3K A;  4YQK A;  3BBD A;  2YY8 A;  2O3A A;  1IPA A;  3BBE A;  4YPY A;  3N4J A;  3E5Y A;  4IG6 A;  1NS5 A;  1UAM A;  3OIN A;  2EGV A;  1TO0 A;  4KGN A;  4YQ3 A;  3NK6 A;  3KTY A;  4X3M A;  4CNF A;  4YQJ A;  2QWV A;  4YPZ A;  4YVK A;  1Z85 A;  4XBO A;  4YQ5 A;  1ZJR A;  4YQO A;  4YQT A;  4FAK A;  1V2X A;  4YQQ A;  4YPW A;  4E8B A;  2EGW A;  3AI9 X;  4YQL A;  4CNG A;  3N4K A;  4YQ8 A;  4YQ1 A;  4YVH A;  1VHY A;  4PZK A;  3ONP A;  4YQD A;  3KNU A;  4JAK A;  5FAI A;  5D9F A;  2I6D A;  4RG1 A;  4JWH A;  3IEF A;  1UAJ A;  1VH0 A;  4YQR A;  2HA8 A;  4KDZ A;  3AIA A;  4JWG A;  3NK7 A;  4CND A;  4J3C A;  5GMC A;  4YQG A;  4YVJ A;  4X3L A;  3QUV A;  3OII A;  1X7P A;  4YQI A;  4YQ6 A;  1MXI A;  4MCD A;  4YQ9 A;  3DCM X;  3L8U A;  3ILK A;  1GZ0 A;  4JAL A;  3BBH A;  3OIJ A;  4YQS A;  3AXZ A;  5CO4 A;  1OY5 A;  3IC6 A;  4JWF A;  3KY7 A;  4H3Z A;  3KW2 A;  3O7B A;  1X7O A;  3GYQ A;  4YQC A;  4MCB A;  5GM8 A;  4YQB A;  2NWA A;  1UAK A;  4FMW A;  4MCC A;  1O6D A;  4CNE A;  4YQA A;  1NXZ A;  2QMM A;  1V6Z A;  4YPX A;  4YQ7 A;  4YVI A;  4L69 A;  2V3J A;  2Z0Y A;  4YQN A;  4YQP A;  4H3Y A;  4YQ0 A;  5GMB A;  4YQ4 A;  2CX8 A;  1P9P A;  1J85 A;  4YVG A;  4JWJ A;  4YQ2 A;  1K3R A;  1UAL A;  1VHK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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