4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
3OIIA 2Z0YA 4JALA 4RG1A 3KY7A 1X7PA 3OINA 3L8UA 3ONPA 4YQTA 4YQRA 4X3LA 4YVKA 2EGWA 5CO4A 4CNFA 1ZJRA 1UAJA 1NXZA 3E5YA 4YQ6A 4IG6A 3O7BA 4JAKA 4MCCA 4YPYA 5GMCA 3IEFA 4YVJA 3QUVA 2NWAA 4YPZA 2I6DA 4KGNA 3OIJA 4MCBA 4YQ8A 3IC6A 4YQNA 4YQJA 3AI9X 4YPWA 1VHKA 4MCDA 4CNGA 4X3MA 3BBDA 1MXIA 4YQCA 4J3CA 4YQLA 4YQSA 4YQ7A 3NK7A 1K3RA 2QMMA 4YVGA 3AIAA 2O3AA 4YQ2A 4YQQA 4YQKA 4YQAA 4YQGA 3KNUA 4YQOA 1VHYA 4YPXA 3GYQA 4YQ9A 1GZ0A 1X7OA 4YQIA 4YQ5A 2V3KA 1UAMA 2EGVA 3NK6A 4E8BA 3N4KA 2YY8A 1J85A 2CX8A 3DCMX 1UALA 4YVHA 3KTYA 3N4JA 4YQPA 3BBHA 4CNDA 1UAKA 1VH0A 3AXZA 4YQ0A 5GM8A 1OY5A 4KDZA 1IPAA 2V3JA 3BBEA 4FAKA 4YVIA 5GMBA 4YQ4A 1NS5A 1P9PA 1V6ZA 2HA8A 3ILKA 4H3YA 1Z85A 1V2XA 1O6DA 4XBOA 1TO0A 4CNEA 4L69A 4YQ1A 5D9FA 4YQBA 4H3ZA 3KW2A 2QWVA 4PZKA 4YQDA 5FAIA 4YQ3A
chains in the Genus database with same CATH superfamily
3OIIA 4JWGA 2Z0YA 1D6KA 4JALA 4RG1A 3KY7A 1QRUA 1X7PA 3OINA 2HZ7A 3L8UA 3ONPA 4YQTA 3DLLS 4X3LA 4YQRA 4YVKA 2EGWA 2ZJRS 5IZNA 5CO4A 4CNFA 4JYZA 4H4KA 1ZJRA 1UAJA 1NXZA 2RE8A 3E5YA 4YQ6A 4WF9S 1EUYA 4IG6A 3O7BA 4JAKA 4MCCA 4YPYA 5GMCA 1EUQA 4P2BA 3IEFA 4YVJA 1NYLA 5GAEW 2NWAA 3QUVA 4YPZA 2I6DA 4KGNA 3OIJA 3X1LB 2PI8A 4MCBA 5BNZA 3IC6A 4YQ8A 3PIPS 4YQNA 4YQJA 3AI9X 4YPWA 1VHKA 4MCDA 4CNGA 5JVHS 4JWJA 4X3MA 1UDXA 3BBDA 1MXIA 4YQCA 4J3CA 4YQLA 4IOAS 4YQSA 3CZBA 4JWFA 4YQ7A 1K3RA 3NK7A 5GAHW 4V194 2QMMA 4YVGA 3AIAA 2O3AA 4YQ2A 4YQQA 4YQKA 4YQAA 5JVGS 4YQGA 5HL7S 3KNUA 4YQOA 1VHYA 2G5DA 4YPXA 3GYQA 4YQ9A 1GZ0A 1X7OA 4YQIA 5GADW 5DM6S 4YQ5A 2V3KA 4JXXA 1UAMA 1EXDA 4UY88 1QTQA 2EGVA 5DM7S 1QRTA 5GAGW 1O0CA 4U67S 3NK6A 3W2WB 1O0BA 4WFBS 4E8BA 3N4KA 2YY8A 4JXZA 1J85A 2PICA 2CX8A 3DCMX 2GAEA 1QRSA 1UALA 4YVHA 3W2VB 3KTYA 3N4JA 4YQPA 3BBHA 4CNDA 1UAKA 2G6GA 1VH0A 2ZJPS 4WFAS 2AE0X 3AXZA 4YQ0A 2ZJQS 1B75A 5GM8A 1DFUP 4FMWA 2PNWA 2PJJA 1OY5A 4IO9S 3PIOS 4KDZA 1IPAA 3J7ZV 2V3JA 3BBEA 4FAKA 4JWHA 3CF5S 1ZJWA 4YVIA 3AIIA 5GMBA 4YQ4A 1NS5A 1P9PA 1V6ZA 1GTRA 2HA8A 3ILKA 4H3YA 1Z85A 2RD2A 1GTSA 1O6DA 1V2XA 1TO0A 4XBOA 4CNEA 1FEUA 4L69A 4WCES 4YQ1A 5D9FA 4YQBA 4IOCS 4WFNS 4H3ZA 4H3SA 3KW2A 2QWVA 4PZKA 4YQDA 5FAIA 4YQ3A
chains in the Genus database with same CATH topology
3OIIA 4JWGA 2Z0YA 4JALA 4RG1A 3KY7A 1X7PA 3OINA 3L8UA 3ONPA 4YQTA 4YQRA 4X3LA 4YVKA 2EGWA 5CO4A 4CNFA 1ZJRA 1UAJA 1NXZA 3E5YA 4YQ6A 4IG6A 3O7BA 4JAKA 4MCCA 4YPYA 5GMCA 3IEFA 4YVJA 3QUVA 2NWAA 4YPZA 2I6DA 4KGNA 3OIJA 4MCBA 4YQ8A 3IC6A 4YQNA 4YQJA 3AI9X 4YPWA 1VHKA 4MCDA 4CNGA 4X3MA 4JWJA 3BBDA 1MXIA 4YQCA 4J3CA 4YQLA 4YQSA 4JWFA 4YQ7A 3NK7A 1K3RA 2QMMA 4YVGA 3AIAA 2O3AA 4YQ2A 4YQQA 4YQKA 4YQAA 4YQGA 3KNUA 4YQOA 1VHYA 4YPXA 3GYQA 4YQ9A 1GZ0A 1X7OA 4YQIA 4YQ5A 2V3KA 1UAMA 2EGVA 3NK6A 4E8BA 3N4KA 2YY8A 1J85A 2CX8A 3DCMX 1UALA 4YVHA 3KTYA 3N4JA 4YQPA 3BBHA 4CNDA 1UAKA 1VH0A 3AXZA 4YQ0A 5GM8A 4FMWA 1OY5A 4KDZA 1IPAA 2V3JA 3BBEA 4FAKA 4JWHA 4YVIA 5GMBA 4YQ4A 1NS5A 1P9PA 1V6ZA 2HA8A 3ILKA 4H3YA 1Z85A 1V2XA 1O6DA 4XBOA 1TO0A 4CNEA 4L69A 4YQ1A 5D9FA 4YQBA 4H3ZA 3KW2A 2QWVA 4PZKA 4YQDA 5FAIA 4YQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OII A;  2Z0Y A;  4JAL A;  4RG1 A;  3KY7 A;  1X7P A;  3OIN A;  3L8U A;  3ONP A;  4YQT A;  4YQR A;  4X3L A;  4YVK A;  2EGW A;  5CO4 A;  4CNF A;  1ZJR A;  1UAJ A;  1NXZ A;  3E5Y A;  4YQ6 A;  4IG6 A;  3O7B A;  4JAK A;  4MCC A;  4YPY A;  5GMC A;  3IEF A;  4YVJ A;  3QUV A;  2NWA A;  4YPZ A;  2I6D A;  4KGN A;  3OIJ A;  4MCB A;  4YQ8 A;  3IC6 A;  4YQN A;  4YQJ A;  3AI9 X;  4YPW A;  1VHK A;  4MCD A;  4CNG A;  4X3M A;  3BBD A;  1MXI A;  4YQC A;  4J3C A;  4YQL A;  4YQS A;  4YQ7 A;  3NK7 A;  1K3R A;  2QMM A;  4YVG A;  3AIA A;  2O3A A;  4YQ2 A;  4YQQ A;  4YQK A;  4YQA A;  4YQG A;  3KNU A;  4YQO A;  1VHY A;  4YPX A;  3GYQ A;  4YQ9 A;  1GZ0 A;  1X7O A;  4YQI A;  4YQ5 A;  2V3K A;  1UAM A;  2EGV A;  3NK6 A;  4E8B A;  3N4K A;  2YY8 A;  1J85 A;  2CX8 A;  3DCM X;  1UAL A;  4YVH A;  3KTY A;  3N4J A;  4YQP A;  3BBH A;  4CND A;  1UAK A;  1VH0 A;  3AXZ A;  4YQ0 A;  5GM8 A;  1OY5 A;  4KDZ A;  1IPA A;  2V3J A;  3BBE A;  4FAK A;  4YVI A;  5GMB A;  4YQ4 A;  1NS5 A;  1P9P A;  1V6Z A;  2HA8 A;  3ILK A;  4H3Y A;  1Z85 A;  1V2X A;  1O6D A;  4XBO A;  1TO0 A;  4CNE A;  4L69 A;  4YQ1 A;  5D9F A;  4YQB A;  4H3Z A;  3KW2 A;  2QWV A;  4PZK A;  4YQD A;  5FAI A;  4YQ3 A; 
#chains in the Genus database with same CATH topology
 3OII A;  4JWG A;  2Z0Y A;  1D6K A;  4JAL A;  4RG1 A;  3KY7 A;  1QRU A;  1X7P A;  3OIN A;  2HZ7 A;  3L8U A;  3ONP A;  4YQT A;  3DLL S;  4X3L A;  4YQR A;  4YVK A;  2EGW A;  2ZJR S;  5IZN A;  5CO4 A;  4CNF A;  4JYZ A;  4H4K A;  1ZJR A;  1UAJ A;  1NXZ A;  2RE8 A;  3E5Y A;  4YQ6 A;  4WF9 S;  1EUY A;  4IG6 A;  3O7B A;  4JAK A;  4MCC A;  4YPY A;  5GMC A;  1EUQ A;  4P2B A;  3IEF A;  4YVJ A;  1NYL A;  5GAE W;  2NWA A;  3QUV A;  4YPZ A;  2I6D A;  4KGN A;  3OIJ A;  3X1L B;  2PI8 A;  4MCB A;  5BNZ A;  3IC6 A;  4YQ8 A;  3PIP S;  4YQN A;  4YQJ A;  3AI9 X;  4YPW A;  1VHK A;  4MCD A;  4CNG A;  5JVH S;  4JWJ A;  4X3M A;  1UDX A;  3BBD A;  1MXI A;  4YQC A;  4J3C A;  4YQL A;  4IOA S;  4YQS A;  3CZB A;  4JWF A;  4YQ7 A;  1K3R A;  3NK7 A;  5GAH W;  4V19 4;  2QMM A;  4YVG A;  3AIA A;  2O3A A;  4YQ2 A;  4YQQ A;  4YQK A;  4YQA A;  5JVG S;  4YQG A;  5HL7 S;  3KNU A;  4YQO A;  1VHY A;  2G5D A;  4YPX A;  3GYQ A;  4YQ9 A;  1GZ0 A;  1X7O A;  4YQI A;  5GAD W;  5DM6 S;  4YQ5 A;  2V3K A;  4JXX A;  1UAM A;  1EXD A;  4UY8 8;  1QTQ A;  2EGV A;  5DM7 S;  1QRT A;  5GAG W;  1O0C A;  4U67 S;  3NK6 A;  3W2W B;  1O0B A;  4WFB S;  4E8B A;  3N4K A;  2YY8 A;  4JXZ A;  1J85 A;  2PIC A;  2CX8 A;  3DCM X;  2GAE A;  1QRS A;  1UAL A;  4YVH A;  3W2V B;  3KTY A;  3N4J A;  4YQP A;  3BBH A;  4CND A;  1UAK A;  2G6G A;  1VH0 A;  2ZJP S;  4WFA S;  2AE0 X;  3AXZ A;  4YQ0 A;  2ZJQ S;  1B75 A;  5GM8 A;  1DFU P;  4FMW A;  2PNW A;  2PJJ A;  1OY5 A;  4IO9 S;  3PIO S;  4KDZ A;  1IPA A;  3J7Z V;  2V3J A;  3BBE A;  4FAK A;  4JWH A;  3CF5 S;  1ZJW A;  4YVI A;  3AII A;  5GMB A;  4YQ4 A;  1NS5 A;  1P9P A;  1V6Z A;  1GTR A;  2HA8 A;  3ILK A;  4H3Y A;  1Z85 A;  2RD2 A;  1GTS A;  1O6D A;  1V2X A;  1TO0 A;  4XBO A;  4CNE A;  1FEU A;  4L69 A;  4WCE S;  4YQ1 A;  5D9F A;  4YQB A;  4IOC S;  4WFN S;  4H3Z A;  4H3S A;  3KW2 A;  2QWV A;  4PZK A;  4YQD A;  5FAI A;  4YQ3 A; 
#chains in the Genus database with same CATH homology
 3OII A;  4JWG A;  2Z0Y A;  4JAL A;  4RG1 A;  3KY7 A;  1X7P A;  3OIN A;  3L8U A;  3ONP A;  4YQT A;  4YQR A;  4X3L A;  4YVK A;  2EGW A;  5CO4 A;  4CNF A;  1ZJR A;  1UAJ A;  1NXZ A;  3E5Y A;  4YQ6 A;  4IG6 A;  3O7B A;  4JAK A;  4MCC A;  4YPY A;  5GMC A;  3IEF A;  4YVJ A;  3QUV A;  2NWA A;  4YPZ A;  2I6D A;  4KGN A;  3OIJ A;  4MCB A;  4YQ8 A;  3IC6 A;  4YQN A;  4YQJ A;  3AI9 X;  4YPW A;  1VHK A;  4MCD A;  4CNG A;  4X3M A;  4JWJ A;  3BBD A;  1MXI A;  4YQC A;  4J3C A;  4YQL A;  4YQS A;  4JWF A;  4YQ7 A;  3NK7 A;  1K3R A;  2QMM A;  4YVG A;  3AIA A;  2O3A A;  4YQ2 A;  4YQQ A;  4YQK A;  4YQA A;  4YQG A;  3KNU A;  4YQO A;  1VHY A;  4YPX A;  3GYQ A;  4YQ9 A;  1GZ0 A;  1X7O A;  4YQI A;  4YQ5 A;  2V3K A;  1UAM A;  2EGV A;  3NK6 A;  4E8B A;  3N4K A;  2YY8 A;  1J85 A;  2CX8 A;  3DCM X;  1UAL A;  4YVH A;  3KTY A;  3N4J A;  4YQP A;  3BBH A;  4CND A;  1UAK A;  1VH0 A;  3AXZ A;  4YQ0 A;  5GM8 A;  4FMW A;  1OY5 A;  4KDZ A;  1IPA A;  2V3J A;  3BBE A;  4FAK A;  4JWH A;  4YVI A;  5GMB A;  4YQ4 A;  1NS5 A;  1P9P A;  1V6Z A;  2HA8 A;  3ILK A;  4H3Y A;  1Z85 A;  1V2X A;  1O6D A;  4XBO A;  1TO0 A;  4CNE A;  4L69 A;  4YQ1 A;  5D9F A;  4YQB A;  4H3Z A;  3KW2 A;  2QWV A;  4PZK A;  4YQD A;  5FAI A;  4YQ3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...