4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal RNA small subunit methyltransferase E
publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
3N4KA 4YQDA 4YQ2A 2EGWA 4YQ3A 4YQGA 1V2XA 4YVKA 4YQQA 4JAKA 4YQ9A 4J3CA 5FAIA 3KTYA 1TO0A 3KW2A 3AIAA 4KGNA 1K3RA 4MCDA 4YQPA 4YVHA 1O6DA 1UAJA 4CNDA 4YQ7A 1Z85A 5D9FA 4FAKA 2QWVA 2YY8A 1X7OA 4YVGA 4YQOA 1V6ZA 2V3KA 4YQ0A 1OY5A 4XBOA 3L8UA 3KY7A 4YQ1A 4YQNA 4YPWA 1NS5A 4IG6A 3N4JA 2QMMA 1J85A 2Z0YA 4YPYA 3OINA 4KDZA 1VHKA 5GMCA 1UAMA 3IC6A 5GM8A 4YQJA 4CNGA 1UAKA 1VH0A 4YQ8A 3NK6A 4L69A 1P9PA 4YQ4A 4X3LA 4YQCA 4YQKA 3QUVA 4YPZA 3OIIA 3AXZA 3BBDA 5CO4A 1ZJRA 4CNEA 4YQBA 1GZ0A 4YPXA 1X7PA 3BBHA 2NWAA 1NXZA 1IPAA 3BBEA 4PZKA 2CX8A 2EGVA 4YVIA 4MCCA 3ONPA 4X3MA 3KNUA 2O3AA 3IEFA 4YQIA 2HA8A 2I6DA 4CNFA 4MCBA 3AI9X 4YQ5A 1VHYA 1UALA 2V3JA 1MXIA 4YQAA 4RG1A 4E8BA 4H3ZA 4H3YA 4YQLA 3O7BA 4YQTA 4YQSA 5GMBA 4YQRA 4YVJA 3GYQA 4YQ6A 3DCMX 4JALA 3E5YA 3OIJA 3NK7A 3ILKA
chains in the Genus database with same CATH superfamily
3N4KA 4YQDA 4YQ2A 2EGWA 4V194 1GTRA 4YQ3A 4YQGA 1V2XA 2PI8A 4YVKA 4YQQA 1EUYA 2PICA 4JAKA 4YQ9A 2RD2A 4J3CA 4U67S 4JXXA 5FAIA 3KTYA 2ZJQS 1TO0A 3KW2A 3AIAA 1D6KA 4KGNA 4H3SA 3ILKA 4JXZA 3X1LB 4IO9S 1K3RA 4MCDA 4YQPA 4YVHA 1O6DA 1UAJA 4CNDA 3W2WB 4JWJA 4YQ7A 1Z85A 5D9FA 5GADW 4FAKA 2QWVA 1QRSA 3PIOS 2YY8A 1X7OA 4YVGA 4YQOA 1V6ZA 1FEUA 5GAGW 2V3KA 4YQ0A 5GAEW 5DM7S 4WCES 4JWGA 1OY5A 4XBOA 3L8UA 3KY7A 5BNZA 4YQ1A 3J7ZV 4YQNA 4YPWA 1O0CA 4WFBS 3CZBA 1EXDA 1NS5A 4IG6A 3N4JA 2QMMA 1J85A 5IZNA 2HZ7A 4IOCS 2Z0YA 1QRUA 4WFAS 4YPYA 3OINA 4KDZA 1VHKA 5GMCA 1UAMA 3IC6A 5GM8A 2G5DA 4YQJA 3DLLS 4CNGA 1UAKA 1VH0A 4YQ8A 3NK6A 2GAEA 2PJJA 4L69A 1P9PA 1GTSA 4YQ4A 1QRTA 4P2BA 3PIPS 4X3LA 4YQKA 4YQCA 3QUVA 5DM6S 4YPZA 3OIIA 1B75A 3AXZA 3BBDA 5CO4A 1ZJRA 4CNEA 4YQBA 1GZ0A 4YPXA 5JVHS 3AIIA 1X7PA 3BBHA 2NWAA 3W2VB 4H4KA 1NXZA 1DFUP 4FMWA 1EUQA 4IOAS 1IPAA 3BBEA 4PZKA 2CX8A 2EGVA 4YVIA 4MCCA 2AE0X 3ONPA 4X3MA 1O0BA 3CF5S 3KNUA 2O3AA 3IEFA 1QTQA 4YQIA 2HA8A 2I6DA 4CNFA 4JYZA 4MCBA 3AI9X 4WFNS 1VHYA 4YQ5A 1UALA 2V3JA 1MXIA 5GAHW 2ZJPS 4YQAA 4RG1A 4E8BA 2ZJRS 4H3ZA 4H3YA 5HL7S 4JWHA 1UDXA 4YQLA 3O7BA 4YQTA 4YQSA 2G6GA 5GMBA 4YQRA 4JWFA 3GYQA 4YQ6A 3DCMX 4YVJA 4JALA 2RE8A 1NYLA 2PNWA 3E5YA 3OIJA 3NK7A 1ZJWA 4UY88 4WF9S 5JVGS
chains in the Genus database with same CATH topology
3N4KA 4YQDA 4YQ2A 2EGWA 4YQ3A 4YQGA 1V2XA 4YVKA 4YQQA 4JAKA 4YQ9A 4J3CA 5FAIA 3KTYA 1TO0A 3KW2A 3AIAA 4KGNA 1K3RA 4MCDA 4YQPA 4YVHA 1O6DA 1UAJA 4CNDA 4JWJA 4YQ7A 1Z85A 5D9FA 4FAKA 2QWVA 2YY8A 1X7OA 4YVGA 4YQOA 1V6ZA 2V3KA 4YQ0A 4JWGA 1OY5A 4XBOA 3L8UA 3KY7A 4YQ1A 4YQNA 4YPWA 1NS5A 4IG6A 3N4JA 2QMMA 1J85A 2Z0YA 4YPYA 3OINA 4KDZA 1VHKA 5GMCA 1UAMA 3IC6A 5GM8A 4YQJA 4CNGA 1UAKA 1VH0A 4YQ8A 3NK6A 4L69A 1P9PA 4YQ4A 4X3LA 4YQCA 4YQKA 3QUVA 4YPZA 3OIIA 3AXZA 3BBDA 5CO4A 1ZJRA 4CNEA 4YQBA 1GZ0A 4YPXA 1X7PA 3BBHA 2NWAA 1NXZA 4FMWA 1IPAA 3BBEA 4PZKA 2CX8A 2EGVA 4YVIA 4MCCA 3ONPA 4X3MA 3KNUA 2O3AA 3IEFA 4YQIA 2HA8A 2I6DA 4CNFA 4MCBA 3AI9X 4YQ5A 1VHYA 1UALA 2V3JA 1MXIA 4YQAA 4RG1A 4E8BA 4H3ZA 4H3YA 4JWHA 4YQLA 3O7BA 4YQTA 4YQSA 5GMBA 4YQRA 4JWFA 3GYQA 4YQ6A 3DCMX 4YVJA 4JALA 3E5YA 3OIJA 3NK7A 3ILKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N4K A;  4YQD A;  4YQ2 A;  2EGW A;  4YQ3 A;  4YQG A;  1V2X A;  4YVK A;  4YQQ A;  4JAK A;  4YQ9 A;  4J3C A;  5FAI A;  3KTY A;  1TO0 A;  3KW2 A;  3AIA A;  4KGN A;  1K3R A;  4MCD A;  4YQP A;  4YVH A;  1O6D A;  1UAJ A;  4CND A;  4YQ7 A;  1Z85 A;  5D9F A;  4FAK A;  2QWV A;  2YY8 A;  1X7O A;  4YVG A;  4YQO A;  1V6Z A;  2V3K A;  4YQ0 A;  1OY5 A;  4XBO A;  3L8U A;  3KY7 A;  4YQ1 A;  4YQN A;  4YPW A;  1NS5 A;  4IG6 A;  3N4J A;  2QMM A;  1J85 A;  2Z0Y A;  4YPY A;  3OIN A;  4KDZ A;  1VHK A;  5GMC A;  1UAM A;  3IC6 A;  5GM8 A;  4YQJ A;  4CNG A;  1UAK A;  1VH0 A;  4YQ8 A;  3NK6 A;  4L69 A;  1P9P A;  4YQ4 A;  4X3L A;  4YQC A;  4YQK A;  3QUV A;  4YPZ A;  3OII A;  3AXZ A;  3BBD A;  5CO4 A;  1ZJR A;  4CNE A;  4YQB A;  1GZ0 A;  4YPX A;  1X7P A;  3BBH A;  2NWA A;  1NXZ A;  1IPA A;  3BBE A;  4PZK A;  2CX8 A;  2EGV A;  4YVI A;  4MCC A;  3ONP A;  4X3M A;  3KNU A;  2O3A A;  3IEF A;  4YQI A;  2HA8 A;  2I6D A;  4CNF A;  4MCB A;  3AI9 X;  4YQ5 A;  1VHY A;  1UAL A;  2V3J A;  1MXI A;  4YQA A;  4RG1 A;  4E8B A;  4H3Z A;  4H3Y A;  4YQL A;  3O7B A;  4YQT A;  4YQS A;  5GMB A;  4YQR A;  4YVJ A;  3GYQ A;  4YQ6 A;  3DCM X;  4JAL A;  3E5Y A;  3OIJ A;  3NK7 A;  3ILK A; 
#chains in the Genus database with same CATH topology
 3N4K A;  4YQD A;  4YQ2 A;  2EGW A;  4V19 4;  1GTR A;  4YQ3 A;  4YQG A;  1V2X A;  2PI8 A;  4YVK A;  4YQQ A;  1EUY A;  2PIC A;  4JAK A;  4YQ9 A;  2RD2 A;  4J3C A;  4U67 S;  4JXX A;  5FAI A;  3KTY A;  2ZJQ S;  1TO0 A;  3KW2 A;  3AIA A;  1D6K A;  4KGN A;  4H3S A;  3ILK A;  4JXZ A;  3X1L B;  4IO9 S;  1K3R A;  4MCD A;  4YQP A;  4YVH A;  1O6D A;  1UAJ A;  4CND A;  3W2W B;  4JWJ A;  4YQ7 A;  1Z85 A;  5D9F A;  5GAD W;  4FAK A;  2QWV A;  1QRS A;  3PIO S;  2YY8 A;  1X7O A;  4YVG A;  4YQO A;  1V6Z A;  1FEU A;  5GAG W;  2V3K A;  4YQ0 A;  5GAE W;  5DM7 S;  4WCE S;  4JWG A;  1OY5 A;  4XBO A;  3L8U A;  3KY7 A;  5BNZ A;  4YQ1 A;  3J7Z V;  4YQN A;  4YPW A;  1O0C A;  4WFB S;  3CZB A;  1EXD A;  1NS5 A;  4IG6 A;  3N4J A;  2QMM A;  1J85 A;  5IZN A;  2HZ7 A;  4IOC S;  2Z0Y A;  1QRU A;  4WFA S;  4YPY A;  3OIN A;  4KDZ A;  1VHK A;  5GMC A;  1UAM A;  3IC6 A;  5GM8 A;  2G5D A;  4YQJ A;  3DLL S;  4CNG A;  1UAK A;  1VH0 A;  4YQ8 A;  3NK6 A;  2GAE A;  2PJJ A;  4L69 A;  1P9P A;  1GTS A;  4YQ4 A;  1QRT A;  4P2B A;  3PIP S;  4X3L A;  4YQK A;  4YQC A;  3QUV A;  5DM6 S;  4YPZ A;  3OII A;  1B75 A;  3AXZ A;  3BBD A;  5CO4 A;  1ZJR A;  4CNE A;  4YQB A;  1GZ0 A;  4YPX A;  5JVH S;  3AII A;  1X7P A;  3BBH A;  2NWA A;  3W2V B;  4H4K A;  1NXZ A;  1DFU P;  4FMW A;  1EUQ A;  4IOA S;  1IPA A;  3BBE A;  4PZK A;  2CX8 A;  2EGV A;  4YVI A;  4MCC A;  2AE0 X;  3ONP A;  4X3M A;  1O0B A;  3CF5 S;  3KNU A;  2O3A A;  3IEF A;  1QTQ A;  4YQI A;  2HA8 A;  2I6D A;  4CNF A;  4JYZ A;  4MCB A;  3AI9 X;  4WFN S;  1VHY A;  4YQ5 A;  1UAL A;  2V3J A;  1MXI A;  5GAH W;  2ZJP S;  4YQA A;  4RG1 A;  4E8B A;  2ZJR S;  4H3Z A;  4H3Y A;  5HL7 S;  4JWH A;  1UDX A;  4YQL A;  3O7B A;  4YQT A;  4YQS A;  2G6G A;  5GMB A;  4YQR A;  4JWF A;  3GYQ A;  4YQ6 A;  3DCM X;  4YVJ A;  4JAL A;  2RE8 A;  1NYL A;  2PNW A;  3E5Y A;  3OIJ A;  3NK7 A;  1ZJW A;  4UY8 8;  4WF9 S;  5JVG S; 
#chains in the Genus database with same CATH homology
 3N4K A;  4YQD A;  4YQ2 A;  2EGW A;  4YQ3 A;  4YQG A;  1V2X A;  4YVK A;  4YQQ A;  4JAK A;  4YQ9 A;  4J3C A;  5FAI A;  3KTY A;  1TO0 A;  3KW2 A;  3AIA A;  4KGN A;  1K3R A;  4MCD A;  4YQP A;  4YVH A;  1O6D A;  1UAJ A;  4CND A;  4JWJ A;  4YQ7 A;  1Z85 A;  5D9F A;  4FAK A;  2QWV A;  2YY8 A;  1X7O A;  4YVG A;  4YQO A;  1V6Z A;  2V3K A;  4YQ0 A;  4JWG A;  1OY5 A;  4XBO A;  3L8U A;  3KY7 A;  4YQ1 A;  4YQN A;  4YPW A;  1NS5 A;  4IG6 A;  3N4J A;  2QMM A;  1J85 A;  2Z0Y A;  4YPY A;  3OIN A;  4KDZ A;  1VHK A;  5GMC A;  1UAM A;  3IC6 A;  5GM8 A;  4YQJ A;  4CNG A;  1UAK A;  1VH0 A;  4YQ8 A;  3NK6 A;  4L69 A;  1P9P A;  4YQ4 A;  4X3L A;  4YQC A;  4YQK A;  3QUV A;  4YPZ A;  3OII A;  3AXZ A;  3BBD A;  5CO4 A;  1ZJR A;  4CNE A;  4YQB A;  1GZ0 A;  4YPX A;  1X7P A;  3BBH A;  2NWA A;  1NXZ A;  4FMW A;  1IPA A;  3BBE A;  4PZK A;  2CX8 A;  2EGV A;  4YVI A;  4MCC A;  3ONP A;  4X3M A;  3KNU A;  2O3A A;  3IEF A;  4YQI A;  2HA8 A;  2I6D A;  4CNF A;  4MCB A;  3AI9 X;  4YQ5 A;  1VHY A;  1UAL A;  2V3J A;  1MXI A;  4YQA A;  4RG1 A;  4E8B A;  4H3Z A;  4H3Y A;  4JWH A;  4YQL A;  3O7B A;  4YQT A;  4YQS A;  5GMB A;  4YQR A;  4JWF A;  3GYQ A;  4YQ6 A;  3DCM X;  4YVJ A;  4JAL A;  3E5Y A;  3OIJ A;  3NK7 A;  3ILK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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