3OINA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 1 molecule of cognate rna
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
225
structure length
217
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 66
structure length 217
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oinA01
3ONPA 1X7PA 4YQCA 2I6DA 3ILKA 4IG6A 4YQNA 4XBOA 4YQ5A 4CNGA 1ZJRA 4CNEA 3AI9X 1TO0A 5GM8A 2Z0YA 3AXZA 3KNUA 4YQSA 1VH0A 4YQGA 3OIIA 1IPAA 1UAJA 3N4JA 4YPZA 3IC6A 5D9FA 5GMCA 2V3KA 4YQLA 1O6DA 4YVIA 2EGWA 4CNFA 3L8UA 4YQTA 3OIJA 3OINA 3O7BA 1NS5A 4YQIA 3KTYA 2YY8A 4H3ZA 2CX8A 4H3YA 1NXZA 5FAIA 4E8BA 5CO4A 3NK6A 5GMBA 3BBDA 3E5YA 4YQPA 4YQAA 4RG1A 4MCBA 4FAKA 4YQ3A 1UALA 4YQDA 3AIAA 1K3RA 4YQBA 4JALA 4YQ1A 1Z85A 1UAKA 3BBHA 1GZ0A 1VHKA 4KDZA 4X3MA 4CNDA 4YQKA 4YQ6A 1MXIA 4J3CA 2QMMA 4YQ7A 4YQ0A 4MCDA 4YQ9A 1V2XA 4YQ4A 4YVKA 1P9PA 2O3AA 4YPYA 3N4KA 3KY7A 3KW2A 4YQQA 2QWVA 4YQOA 3DCMX 4MCCA 4YPWA 4KGNA 4YQRA 4L69A 1OY5A 1UAMA 3GYQA 4YVGA 2V3JA 3NK7A 1J85A 1V6ZA 4YPXA 2HA8A 4PZKA 4YQ8A 4JAKA 4YVJA 4YQ2A 1X7OA 1VHYA 4YVHA 3QUVA 4YQJA 2EGVA 3IEFA 3BBEA 4X3LA
chains in the Genus database with same CATH superfamily
3ONPA 1X7PA 4YQCA 2I6DA 3ILKA 4IG6A 4YQNA 4XBOA 4YQ5A 4CNGA 1ZJRA 4CNEA 3AI9X 1TO0A 4JWFA 5GM8A 2Z0YA 3AXZA 3KNUA 4YQSA 1VH0A 4YQGA 3OIIA 1IPAA 1UAJA 4FMWA 3N4JA 4YPZA 3IC6A 5D9FA 5GMCA 2V3KA 4YQLA 1O6DA 4YVIA 2EGWA 4CNFA 3L8UA 4YQTA 3OIJA 3OINA 3O7BA 1NS5A 4YQIA 3KTYA 2YY8A 4H3ZA 2CX8A 4H3YA 1NXZA 5FAIA 4E8BA 5CO4A 3NK6A 5GMBA 3BBDA 3E5YA 4YQPA 4YQAA 4JWGA 4RG1A 4MCBA 4FAKA 4YQ3A 1UALA 4JWJA 4YQDA 3AIAA 1K3RA 4YQBA 4JALA 4YQ1A 1Z85A 1UAKA 3BBHA 1GZ0A 1VHKA 4KDZA 4X3MA 4CNDA 4YQKA 4YQ6A 1MXIA 4J3CA 2QMMA 4YQ7A 4YQ0A 4MCDA 4YQ9A 1V2XA 4YQ4A 4YVKA 1P9PA 2O3AA 4YPYA 3N4KA 3KY7A 3KW2A 4YQQA 2QWVA 4YQOA 3DCMX 4MCCA 4YPWA 4KGNA 4YQRA 4L69A 1OY5A 1UAMA 3GYQA 4YVGA 2V3JA 3NK7A 1J85A 4JWHA 1V6ZA 4YPXA 2HA8A 4PZKA 4YQ8A 4JAKA 4YVJA 4YQ2A 1X7OA 1VHYA 4YVHA 3QUVA 4YQJA 2EGVA 3IEFA 3BBEA 4X3LA
chains in the Genus database with same CATH topology
3ONPA 1X7PA 4YQCA 2I6DA 3ILKA 4IG6A 4YQNA 4XBOA 4YQ5A 4CNGA 1ZJRA 4CNEA 3AI9X 1TO0A 4JWFA 5GM8A 2Z0YA 3AXZA 3KNUA 4YQSA 1VH0A 4YQGA 3OIIA 1IPAA 1UAJA 4FMWA 3N4JA 4YPZA 3IC6A 5D9FA 5GMCA 2V3KA 4YQLA 1O6DA 4YVIA 2EGWA 4CNFA 3L8UA 4YQTA 3OIJA 3OINA 3O7BA 1NS5A 4YQIA 3KTYA 2YY8A 4H3ZA 2CX8A 4H3YA 1NXZA 5FAIA 4E8BA 5CO4A 3NK6A 5GMBA 3BBDA 3E5YA 4YQPA 4YQAA 4JWGA 4RG1A 4MCBA 4FAKA 4YQ3A 1UALA 4JWJA 4YQDA 3AIAA 1K3RA 4YQBA 4JALA 4YQ1A 1Z85A 1UAKA 3BBHA 1GZ0A 1VHKA 4KDZA 4X3MA 4CNDA 4YQKA 4YQ6A 1MXIA 4J3CA 2QMMA 4YQ7A 4YQ0A 4MCDA 4YQ9A 1V2XA 4YQ4A 4YVKA 1P9PA 2O3AA 4YPYA 3N4KA 3KY7A 3KW2A 4YQQA 2QWVA 4YQOA 3DCMX 4MCCA 4YPWA 4KGNA 4YQRA 4L69A 1OY5A 1UAMA 3GYQA 4YVGA 2V3JA 3NK7A 1J85A 4JWHA 1V6ZA 4YPXA 2HA8A 4PZKA 4YQ8A 4JAKA 4YVJA 4YQ2A 1X7OA 1VHYA 4YVHA 3QUVA 4YQJA 2EGVA 3IEFA 3BBEA 4X3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ONP A;  1X7P A;  4YQC A;  2I6D A;  3ILK A;  4IG6 A;  4YQN A;  4XBO A;  4YQ5 A;  4CNG A;  1ZJR A;  4CNE A;  3AI9 X;  1TO0 A;  5GM8 A;  2Z0Y A;  3AXZ A;  3KNU A;  4YQS A;  1VH0 A;  4YQG A;  3OII A;  1IPA A;  1UAJ A;  3N4J A;  4YPZ A;  3IC6 A;  5D9F A;  5GMC A;  2V3K A;  4YQL A;  1O6D A;  4YVI A;  2EGW A;  4CNF A;  3L8U A;  4YQT A;  3OIJ A;  3OIN A;  3O7B A;  1NS5 A;  4YQI A;  3KTY A;  2YY8 A;  4H3Z A;  2CX8 A;  4H3Y A;  1NXZ A;  5FAI A;  4E8B A;  5CO4 A;  3NK6 A;  5GMB A;  3BBD A;  3E5Y A;  4YQP A;  4YQA A;  4RG1 A;  4MCB A;  4FAK A;  4YQ3 A;  1UAL A;  4YQD A;  3AIA A;  1K3R A;  4YQB A;  4JAL A;  4YQ1 A;  1Z85 A;  1UAK A;  3BBH A;  1GZ0 A;  1VHK A;  4KDZ A;  4X3M A;  4CND A;  4YQK A;  4YQ6 A;  1MXI A;  4J3C A;  2QMM A;  4YQ7 A;  4YQ0 A;  4MCD A;  4YQ9 A;  1V2X A;  4YQ4 A;  4YVK A;  1P9P A;  2O3A A;  4YPY A;  3N4K A;  3KY7 A;  3KW2 A;  4YQQ A;  2QWV A;  4YQO A;  3DCM X;  4MCC A;  4YPW A;  4KGN A;  4YQR A;  4L69 A;  1OY5 A;  1UAM A;  3GYQ A;  4YVG A;  2V3J A;  3NK7 A;  1J85 A;  1V6Z A;  4YPX A;  2HA8 A;  4PZK A;  4YQ8 A;  4JAK A;  4YVJ A;  4YQ2 A;  1X7O A;  1VHY A;  4YVH A;  3QUV A;  4YQJ A;  2EGV A;  3IEF A;  3BBE A;  4X3L A; 
#chains in the Genus database with same CATH topology
 3ONP A;  1X7P A;  4YQC A;  2I6D A;  3ILK A;  4IG6 A;  4YQN A;  4XBO A;  4YQ5 A;  4CNG A;  1ZJR A;  4CNE A;  3AI9 X;  1TO0 A;  4JWF A;  5GM8 A;  2Z0Y A;  3AXZ A;  3KNU A;  4YQS A;  1VH0 A;  4YQG A;  3OII A;  1IPA A;  1UAJ A;  4FMW A;  3N4J A;  4YPZ A;  3IC6 A;  5D9F A;  5GMC A;  2V3K A;  4YQL A;  1O6D A;  4YVI A;  2EGW A;  4CNF A;  3L8U A;  4YQT A;  3OIJ A;  3OIN A;  3O7B A;  1NS5 A;  4YQI A;  3KTY A;  2YY8 A;  4H3Z A;  2CX8 A;  4H3Y A;  1NXZ A;  5FAI A;  4E8B A;  5CO4 A;  3NK6 A;  5GMB A;  3BBD A;  3E5Y A;  4YQP A;  4YQA A;  4JWG A;  4RG1 A;  4MCB A;  4FAK A;  4YQ3 A;  1UAL A;  4JWJ A;  4YQD A;  3AIA A;  1K3R A;  4YQB A;  4JAL A;  4YQ1 A;  1Z85 A;  1UAK A;  3BBH A;  1GZ0 A;  1VHK A;  4KDZ A;  4X3M A;  4CND A;  4YQK A;  4YQ6 A;  1MXI A;  4J3C A;  2QMM A;  4YQ7 A;  4YQ0 A;  4MCD A;  4YQ9 A;  1V2X A;  4YQ4 A;  4YVK A;  1P9P A;  2O3A A;  4YPY A;  3N4K A;  3KY7 A;  3KW2 A;  4YQQ A;  2QWV A;  4YQO A;  3DCM X;  4MCC A;  4YPW A;  4KGN A;  4YQR A;  4L69 A;  1OY5 A;  1UAM A;  3GYQ A;  4YVG A;  2V3J A;  3NK7 A;  1J85 A;  4JWH A;  1V6Z A;  4YPX A;  2HA8 A;  4PZK A;  4YQ8 A;  4JAK A;  4YVJ A;  4YQ2 A;  1X7O A;  1VHY A;  4YVH A;  3QUV A;  4YQJ A;  2EGV A;  3IEF A;  3BBE A;  4X3L A; 
#chains in the Genus database with same CATH homology
 3ONP A;  1X7P A;  4YQC A;  2I6D A;  3ILK A;  4IG6 A;  4YQN A;  4XBO A;  4YQ5 A;  4CNG A;  1ZJR A;  4CNE A;  3AI9 X;  1TO0 A;  4JWF A;  5GM8 A;  2Z0Y A;  3AXZ A;  3KNU A;  4YQS A;  1VH0 A;  4YQG A;  3OII A;  1IPA A;  1UAJ A;  4FMW A;  3N4J A;  4YPZ A;  3IC6 A;  5D9F A;  5GMC A;  2V3K A;  4YQL A;  1O6D A;  4YVI A;  2EGW A;  4CNF A;  3L8U A;  4YQT A;  3OIJ A;  3OIN A;  3O7B A;  1NS5 A;  4YQI A;  3KTY A;  2YY8 A;  4H3Z A;  2CX8 A;  4H3Y A;  1NXZ A;  5FAI A;  4E8B A;  5CO4 A;  3NK6 A;  5GMB A;  3BBD A;  3E5Y A;  4YQP A;  4YQA A;  4JWG A;  4RG1 A;  4MCB A;  4FAK A;  4YQ3 A;  1UAL A;  4JWJ A;  4YQD A;  3AIA A;  1K3R A;  4YQB A;  4JAL A;  4YQ1 A;  1Z85 A;  1UAK A;  3BBH A;  1GZ0 A;  1VHK A;  4KDZ A;  4X3M A;  4CND A;  4YQK A;  4YQ6 A;  1MXI A;  4J3C A;  2QMM A;  4YQ7 A;  4YQ0 A;  4MCD A;  4YQ9 A;  1V2X A;  4YQ4 A;  4YVK A;  1P9P A;  2O3A A;  4YPY A;  3N4K A;  3KY7 A;  3KW2 A;  4YQQ A;  2QWV A;  4YQO A;  3DCM X;  4MCC A;  4YPW A;  4KGN A;  4YQR A;  4L69 A;  1OY5 A;  1UAM A;  3GYQ A;  4YVG A;  2V3J A;  3NK7 A;  1J85 A;  4JWH A;  1V6Z A;  4YPX A;  2HA8 A;  4PZK A;  4YQ8 A;  4JAK A;  4YVJ A;  4YQ2 A;  1X7O A;  1VHY A;  4YVH A;  3QUV A;  4YQJ A;  2EGV A;  3IEF A;  3BBE A;  4X3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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