3O7BA

Crystal structure of archaeoglobus fulgidus nep1 bound to s-adenosylhomocysteine
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
Knots found
sequence length
216
structure length
216
Chain Sequence
MGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAMKSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRLPRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREKGGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSLYVTSRVLCEYERVRAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Transferase
source organism Archaeoglobus fulgidus
molecule keywords Ribosome biogenesis Nep1 RNA methyltransferase
total genus 75
structure length 216
sequence length 216
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2010-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3o7bA00
4JALA 4MCBA 1UAMA 4RG1A 2V3KA 4YQ2A 4YVJA 4YQOA 4KDZA 3GYQA 4YPYA 3N4KA 1V6ZA 2HA8A 2EGWA 3NK6A 1MXIA 3BBEA 3BBHA 1OY5A 4MCDA 4CNFA 4YQGA 4YQSA 2QWVA 4YPWA 4YPZA 3KY7A 4YQ6A 4YQNA 4X3LA 1J85A 1UAJA 1VH0A 1UAKA 4X3MA 4YQ8A 3ONPA 1NS5A 2YY8A 3IEFA 5GM8A 4JAKA 4YQ3A 5GMCA 3QUVA 1X7OA 3N4JA 4J3CA 3ILKA 4YQRA 4YQCA 4L69A 4CNEA 4H3ZA 4YQ5A 4YQKA 5D9FA 5FAIA 4YQ1A 3KW2A 3BBDA 5GMBA 3AI9X 2EGVA 4YQAA 4YQTA 4XBOA 4YVGA 1ZJRA 3KNUA 5CO4A 1VHYA 4YQ9A 1X7PA 3IC6A 4CNDA 4YVHA 4YVIA 3O7BA 1NXZA 4CNGA 3OIJA 4PZKA 1Z85A 4KGNA 1IPAA 1O6DA 1TO0A 4IG6A 4YQLA 3AIAA 2I6DA 4H3YA 1V2XA 2QMMA 3L8UA 3AXZA 4YQDA 3NK7A 1GZ0A 4YQ0A 4YQBA 4YQPA 4E8BA 4YQJA 3OINA 3OIIA 3DCMX 3KTYA 1K3RA 2V3JA 4YQ7A 4YPXA 4YVKA 4YQ4A 3E5YA 1P9PA 1VHKA 2CX8A 1UALA 2O3AA 2Z0YA 4MCCA 4YQQA 4YQIA 4FAKA
chains in the Genus database with same CATH superfamily
4JALA 4MCBA 1UAMA 4RG1A 2V3KA 4YQ2A 4YVJA 4YQOA 4KDZA 3GYQA 4YPYA 3N4KA 1V6ZA 2HA8A 2EGWA 3NK6A 1MXIA 3BBEA 3BBHA 1OY5A 4MCDA 4CNFA 4YQGA 4YQSA 2QWVA 4YPWA 4YPZA 4FMWA 3KY7A 4YQ6A 4JWGA 4YQNA 4X3LA 1J85A 1UAJA 1VH0A 1UAKA 4X3MA 4YQ8A 3ONPA 1NS5A 2YY8A 3IEFA 5GM8A 4JAKA 4YQ3A 5GMCA 3QUVA 4JWHA 1X7OA 3N4JA 4J3CA 3ILKA 4YQRA 4YQCA 4L69A 4CNEA 4H3ZA 4YQ5A 4YQKA 5D9FA 5FAIA 4YQ1A 3KW2A 3BBDA 5GMBA 3AI9X 2EGVA 4JWFA 4YQAA 4YQTA 4XBOA 4YVGA 1ZJRA 3KNUA 5CO4A 1VHYA 4YQ9A 1X7PA 3IC6A 4CNDA 4YVHA 4YVIA 3O7BA 1NXZA 4CNGA 3OIJA 4PZKA 1Z85A 4KGNA 1IPAA 4JWJA 1O6DA 1TO0A 4IG6A 4YQLA 3AIAA 2I6DA 4H3YA 1V2XA 2QMMA 3L8UA 3AXZA 4YQDA 3NK7A 1GZ0A 4YQ0A 4YQBA 4YQPA 4E8BA 4YQJA 3OINA 3OIIA 3DCMX 3KTYA 1K3RA 2V3JA 4YQ7A 4YPXA 4YVKA 4YQ4A 3E5YA 1P9PA 1VHKA 2CX8A 1UALA 2O3AA 2Z0YA 4MCCA 4YQQA 4YQIA 4FAKA
chains in the Genus database with same CATH topology
4JALA 4MCBA 1UAMA 4RG1A 2V3KA 4YQ2A 4YVJA 4YQOA 4KDZA 3GYQA 4YPYA 3N4KA 1V6ZA 2HA8A 2EGWA 3NK6A 1MXIA 3BBEA 3BBHA 1OY5A 4MCDA 4CNFA 4YQGA 4YQSA 2QWVA 4YPWA 4YPZA 4FMWA 3KY7A 4YQ6A 4JWGA 4YQNA 4X3LA 1J85A 1UAJA 1VH0A 1UAKA 4X3MA 4YQ8A 3ONPA 1NS5A 2YY8A 3IEFA 5GM8A 4JAKA 4YQ3A 5GMCA 3QUVA 4JWHA 1X7OA 3N4JA 4J3CA 3ILKA 4YQRA 4YQCA 4L69A 4CNEA 4H3ZA 4YQ5A 4YQKA 5D9FA 5FAIA 4YQ1A 3KW2A 3BBDA 5GMBA 3AI9X 2EGVA 4JWFA 4YQAA 4YQTA 4XBOA 4YVGA 1ZJRA 3KNUA 5CO4A 1VHYA 4YQ9A 1X7PA 3IC6A 4CNDA 4YVHA 4YVIA 3O7BA 1NXZA 4CNGA 3OIJA 4PZKA 1Z85A 4KGNA 1IPAA 4JWJA 1O6DA 1TO0A 4IG6A 4YQLA 3AIAA 2I6DA 4H3YA 1V2XA 2QMMA 3L8UA 3AXZA 4YQDA 3NK7A 1GZ0A 4YQ0A 4YQBA 4YQPA 4E8BA 4YQJA 3OINA 3OIIA 3DCMX 3KTYA 1K3RA 2V3JA 4YQ7A 4YPXA 4YVKA 4YQ4A 3E5YA 1P9PA 1VHKA 2CX8A 1UALA 2O3AA 2Z0YA 4MCCA 4YQQA 4YQIA 4FAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAL A;  4MCB A;  1UAM A;  4RG1 A;  2V3K A;  4YQ2 A;  4YVJ A;  4YQO A;  4KDZ A;  3GYQ A;  4YPY A;  3N4K A;  1V6Z A;  2HA8 A;  2EGW A;  3NK6 A;  1MXI A;  3BBE A;  3BBH A;  1OY5 A;  4MCD A;  4CNF A;  4YQG A;  4YQS A;  2QWV A;  4YPW A;  4YPZ A;  3KY7 A;  4YQ6 A;  4YQN A;  4X3L A;  1J85 A;  1UAJ A;  1VH0 A;  1UAK A;  4X3M A;  4YQ8 A;  3ONP A;  1NS5 A;  2YY8 A;  3IEF A;  5GM8 A;  4JAK A;  4YQ3 A;  5GMC A;  3QUV A;  1X7O A;  3N4J A;  4J3C A;  3ILK A;  4YQR A;  4YQC A;  4L69 A;  4CNE A;  4H3Z A;  4YQ5 A;  4YQK A;  5D9F A;  5FAI A;  4YQ1 A;  3KW2 A;  3BBD A;  5GMB A;  3AI9 X;  2EGV A;  4YQA A;  4YQT A;  4XBO A;  4YVG A;  1ZJR A;  3KNU A;  5CO4 A;  1VHY A;  4YQ9 A;  1X7P A;  3IC6 A;  4CND A;  4YVH A;  4YVI A;  3O7B A;  1NXZ A;  4CNG A;  3OIJ A;  4PZK A;  1Z85 A;  4KGN A;  1IPA A;  1O6D A;  1TO0 A;  4IG6 A;  4YQL A;  3AIA A;  2I6D A;  4H3Y A;  1V2X A;  2QMM A;  3L8U A;  3AXZ A;  4YQD A;  3NK7 A;  1GZ0 A;  4YQ0 A;  4YQB A;  4YQP A;  4E8B A;  4YQJ A;  3OIN A;  3OII A;  3DCM X;  3KTY A;  1K3R A;  2V3J A;  4YQ7 A;  4YPX A;  4YVK A;  4YQ4 A;  3E5Y A;  1P9P A;  1VHK A;  2CX8 A;  1UAL A;  2O3A A;  2Z0Y A;  4MCC A;  4YQQ A;  4YQI A;  4FAK A; 
#chains in the Genus database with same CATH topology
 4JAL A;  4MCB A;  1UAM A;  4RG1 A;  2V3K A;  4YQ2 A;  4YVJ A;  4YQO A;  4KDZ A;  3GYQ A;  4YPY A;  3N4K A;  1V6Z A;  2HA8 A;  2EGW A;  3NK6 A;  1MXI A;  3BBE A;  3BBH A;  1OY5 A;  4MCD A;  4CNF A;  4YQG A;  4YQS A;  2QWV A;  4YPW A;  4YPZ A;  4FMW A;  3KY7 A;  4YQ6 A;  4JWG A;  4YQN A;  4X3L A;  1J85 A;  1UAJ A;  1VH0 A;  1UAK A;  4X3M A;  4YQ8 A;  3ONP A;  1NS5 A;  2YY8 A;  3IEF A;  5GM8 A;  4JAK A;  4YQ3 A;  5GMC A;  3QUV A;  4JWH A;  1X7O A;  3N4J A;  4J3C A;  3ILK A;  4YQR A;  4YQC A;  4L69 A;  4CNE A;  4H3Z A;  4YQ5 A;  4YQK A;  5D9F A;  5FAI A;  4YQ1 A;  3KW2 A;  3BBD A;  5GMB A;  3AI9 X;  2EGV A;  4JWF A;  4YQA A;  4YQT A;  4XBO A;  4YVG A;  1ZJR A;  3KNU A;  5CO4 A;  1VHY A;  4YQ9 A;  1X7P A;  3IC6 A;  4CND A;  4YVH A;  4YVI A;  3O7B A;  1NXZ A;  4CNG A;  3OIJ A;  4PZK A;  1Z85 A;  4KGN A;  1IPA A;  4JWJ A;  1O6D A;  1TO0 A;  4IG6 A;  4YQL A;  3AIA A;  2I6D A;  4H3Y A;  1V2X A;  2QMM A;  3L8U A;  3AXZ A;  4YQD A;  3NK7 A;  1GZ0 A;  4YQ0 A;  4YQB A;  4YQP A;  4E8B A;  4YQJ A;  3OIN A;  3OII A;  3DCM X;  3KTY A;  1K3R A;  2V3J A;  4YQ7 A;  4YPX A;  4YVK A;  4YQ4 A;  3E5Y A;  1P9P A;  1VHK A;  2CX8 A;  1UAL A;  2O3A A;  2Z0Y A;  4MCC A;  4YQQ A;  4YQI A;  4FAK A; 
#chains in the Genus database with same CATH homology
 4JAL A;  4MCB A;  1UAM A;  4RG1 A;  2V3K A;  4YQ2 A;  4YVJ A;  4YQO A;  4KDZ A;  3GYQ A;  4YPY A;  3N4K A;  1V6Z A;  2HA8 A;  2EGW A;  3NK6 A;  1MXI A;  3BBE A;  3BBH A;  1OY5 A;  4MCD A;  4CNF A;  4YQG A;  4YQS A;  2QWV A;  4YPW A;  4YPZ A;  4FMW A;  3KY7 A;  4YQ6 A;  4JWG A;  4YQN A;  4X3L A;  1J85 A;  1UAJ A;  1VH0 A;  1UAK A;  4X3M A;  4YQ8 A;  3ONP A;  1NS5 A;  2YY8 A;  3IEF A;  5GM8 A;  4JAK A;  4YQ3 A;  5GMC A;  3QUV A;  4JWH A;  1X7O A;  3N4J A;  4J3C A;  3ILK A;  4YQR A;  4YQC A;  4L69 A;  4CNE A;  4H3Z A;  4YQ5 A;  4YQK A;  5D9F A;  5FAI A;  4YQ1 A;  3KW2 A;  3BBD A;  5GMB A;  3AI9 X;  2EGV A;  4JWF A;  4YQA A;  4YQT A;  4XBO A;  4YVG A;  1ZJR A;  3KNU A;  5CO4 A;  1VHY A;  4YQ9 A;  1X7P A;  3IC6 A;  4CND A;  4YVH A;  4YVI A;  3O7B A;  1NXZ A;  4CNG A;  3OIJ A;  4PZK A;  1Z85 A;  4KGN A;  1IPA A;  4JWJ A;  1O6D A;  1TO0 A;  4IG6 A;  4YQL A;  3AIA A;  2I6D A;  4H3Y A;  1V2X A;  2QMM A;  3L8U A;  3AXZ A;  4YQD A;  3NK7 A;  1GZ0 A;  4YQ0 A;  4YQB A;  4YQP A;  4E8B A;  4YQJ A;  3OIN A;  3OII A;  3DCM X;  3KTY A;  1K3R A;  2V3J A;  4YQ7 A;  4YPX A;  4YVK A;  4YQ4 A;  3E5Y A;  1P9P A;  1VHK A;  2CX8 A;  1UAL A;  2O3A A;  2Z0Y A;  4MCC A;  4YQQ A;  4YQI A;  4FAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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