2V3KA

The yeast ribosome synthesis factor emg1 alpha beta knot fold methyltransferase
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
Knots found
sequence length
227
structure length
218
Chain Sequence
PQAPPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ESSENTIAL FOR MITOTIC GROWTH 1
publication title The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Ribosomal protein
total genus 58
structure length 218
sequence length 227
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2007-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2v3kA01
4MCDA 3NK6A 4CNGA 2QMMA 1NXZA 3KNUA 3GYQA 3BBEA 3N4KA 4YQCA 4YVKA 1MXIA 4JALA 1UAMA 1K3RA 1UALA 4YQIA 2V3JA 4YPXA 3ONPA 1OY5A 5GMCA 4YQ1A 4YPYA 1VHYA 4X3MA 2YY8A 4MCCA 3ILKA 2EGVA 4YQ4A 3OIIA 4X3LA 4YQGA 1TO0A 3L8UA 2I6DA 4CNFA 4RG1A 3BBDA 4YVGA 1P9PA 4YQ3A 4YQJA 5D9FA 3OIJA 2Z0YA 4YQKA 3O7BA 1GZ0A 4YQAA 1UAJA 4YQ5A 4YVJA 4YVIA 4YQ2A 4CNDA 3IC6A 3E5YA 4FAKA 4CNEA 3QUVA 1VH0A 4YPZA 5GMBA 4YQRA 1Z85A 3DCMX 4E8BA 4IG6A 3IEFA 1NS5A 2HA8A 4YPWA 1IPAA 1ZJRA 4KDZA 4YQ9A 1UAKA 4PZKA 4YQDA 4YQOA 4YQQA 1VHKA 4XBOA 2V3KA 2O3AA 3AI9X 2QWVA 1V6ZA 4MCBA 3AIAA 5GM8A 1J85A 4J3CA 4YQ6A 1O6DA 4YQSA 5FAIA 3NK7A 1V2XA 1X7OA 4L69A 1X7PA 3AXZA 3KW2A 4H3YA 2EGWA 4YQ0A 5CO4A 4YQBA 4YQPA 4YQLA 4H3ZA 3KY7A 3KTYA 4YVHA 4YQ8A 2CX8A 4KGNA 4YQTA 3N4JA 3BBHA 3OINA 4JAKA 4YQ7A 4YQNA
chains in the Genus database with same CATH superfamily
4MCDA 3NK6A 4CNGA 2QMMA 1NXZA 3KNUA 3GYQA 3BBEA 3N4KA 4YQCA 4YVKA 1MXIA 4JALA 1UAMA 1K3RA 1UALA 4YQIA 2V3JA 4YPXA 3ONPA 1OY5A 5GMCA 4YQ1A 4YPYA 1VHYA 4X3MA 2YY8A 4MCCA 3ILKA 2EGVA 4JWFA 4YQ4A 4FMWA 3OIIA 4X3LA 4YQGA 1TO0A 3L8UA 4JWJA 2I6DA 4CNFA 4RG1A 3BBDA 4YVGA 1P9PA 4YQ3A 4YQJA 5D9FA 3OIJA 2Z0YA 4JWGA 4YQKA 3O7BA 4JWHA 1GZ0A 4YQAA 1UAJA 4YQ5A 4YVJA 4YVIA 4YQ2A 4CNDA 3IC6A 3E5YA 4FAKA 4CNEA 3QUVA 1VH0A 4YPZA 5GMBA 4YQRA 1Z85A 3DCMX 4E8BA 4IG6A 3IEFA 1NS5A 2HA8A 4YPWA 1IPAA 1ZJRA 4KDZA 4YQ9A 1UAKA 4PZKA 4YQDA 4YQOA 4YQQA 1VHKA 4XBOA 2V3KA 2O3AA 3AI9X 2QWVA 1V6ZA 4MCBA 3AIAA 5GM8A 1J85A 4J3CA 4YQ6A 1O6DA 4YQSA 5FAIA 3NK7A 1V2XA 1X7OA 4L69A 1X7PA 3AXZA 3KW2A 4H3YA 2EGWA 4YQ0A 5CO4A 4YQBA 4YQPA 4YQLA 4H3ZA 3KY7A 3KTYA 4YVHA 4YQ8A 2CX8A 4KGNA 4YQTA 3N4JA 3BBHA 3OINA 4JAKA 4YQ7A 4YQNA
chains in the Genus database with same CATH topology
4MCDA 3NK6A 4CNGA 2QMMA 1NXZA 3KNUA 3GYQA 3BBEA 3N4KA 4YQCA 4YVKA 1MXIA 4JALA 1UAMA 1K3RA 1UALA 4YQIA 2V3JA 4YPXA 3ONPA 1OY5A 5GMCA 4YQ1A 4YPYA 1VHYA 4X3MA 2YY8A 4MCCA 3ILKA 2EGVA 4JWFA 4YQ4A 4FMWA 3OIIA 4X3LA 4YQGA 1TO0A 3L8UA 4JWJA 2I6DA 4CNFA 4RG1A 3BBDA 4YVGA 1P9PA 4YQ3A 4YQJA 5D9FA 3OIJA 2Z0YA 4JWGA 4YQKA 3O7BA 4JWHA 1GZ0A 4YQAA 1UAJA 4YQ5A 4YVJA 4YVIA 4YQ2A 4CNDA 3IC6A 3E5YA 4FAKA 4CNEA 3QUVA 1VH0A 4YPZA 5GMBA 4YQRA 1Z85A 3DCMX 4E8BA 4IG6A 3IEFA 1NS5A 2HA8A 4YPWA 1IPAA 1ZJRA 4KDZA 4YQ9A 1UAKA 4PZKA 4YQDA 4YQOA 4YQQA 1VHKA 4XBOA 2V3KA 2O3AA 3AI9X 2QWVA 1V6ZA 4MCBA 3AIAA 5GM8A 1J85A 4J3CA 4YQ6A 1O6DA 4YQSA 5FAIA 3NK7A 1V2XA 1X7OA 4L69A 1X7PA 3AXZA 3KW2A 4H3YA 2EGWA 4YQ0A 5CO4A 4YQBA 4YQPA 4YQLA 4H3ZA 3KY7A 3KTYA 4YVHA 4YQ8A 2CX8A 4KGNA 4YQTA 3N4JA 3BBHA 3OINA 4JAKA 4YQ7A 4YQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MCD A;  3NK6 A;  4CNG A;  2QMM A;  1NXZ A;  3KNU A;  3GYQ A;  3BBE A;  3N4K A;  4YQC A;  4YVK A;  1MXI A;  4JAL A;  1UAM A;  1K3R A;  1UAL A;  4YQI A;  2V3J A;  4YPX A;  3ONP A;  1OY5 A;  5GMC A;  4YQ1 A;  4YPY A;  1VHY A;  4X3M A;  2YY8 A;  4MCC A;  3ILK A;  2EGV A;  4YQ4 A;  3OII A;  4X3L A;  4YQG A;  1TO0 A;  3L8U A;  2I6D A;  4CNF A;  4RG1 A;  3BBD A;  4YVG A;  1P9P A;  4YQ3 A;  4YQJ A;  5D9F A;  3OIJ A;  2Z0Y A;  4YQK A;  3O7B A;  1GZ0 A;  4YQA A;  1UAJ A;  4YQ5 A;  4YVJ A;  4YVI A;  4YQ2 A;  4CND A;  3IC6 A;  3E5Y A;  4FAK A;  4CNE A;  3QUV A;  1VH0 A;  4YPZ A;  5GMB A;  4YQR A;  1Z85 A;  3DCM X;  4E8B A;  4IG6 A;  3IEF A;  1NS5 A;  2HA8 A;  4YPW A;  1IPA A;  1ZJR A;  4KDZ A;  4YQ9 A;  1UAK A;  4PZK A;  4YQD A;  4YQO A;  4YQQ A;  1VHK A;  4XBO A;  2V3K A;  2O3A A;  3AI9 X;  2QWV A;  1V6Z A;  4MCB A;  3AIA A;  5GM8 A;  1J85 A;  4J3C A;  4YQ6 A;  1O6D A;  4YQS A;  5FAI A;  3NK7 A;  1V2X A;  1X7O A;  4L69 A;  1X7P A;  3AXZ A;  3KW2 A;  4H3Y A;  2EGW A;  4YQ0 A;  5CO4 A;  4YQB A;  4YQP A;  4YQL A;  4H3Z A;  3KY7 A;  3KTY A;  4YVH A;  4YQ8 A;  2CX8 A;  4KGN A;  4YQT A;  3N4J A;  3BBH A;  3OIN A;  4JAK A;  4YQ7 A;  4YQN A; 
#chains in the Genus database with same CATH topology
 4MCD A;  3NK6 A;  4CNG A;  2QMM A;  1NXZ A;  3KNU A;  3GYQ A;  3BBE A;  3N4K A;  4YQC A;  4YVK A;  1MXI A;  4JAL A;  1UAM A;  1K3R A;  1UAL A;  4YQI A;  2V3J A;  4YPX A;  3ONP A;  1OY5 A;  5GMC A;  4YQ1 A;  4YPY A;  1VHY A;  4X3M A;  2YY8 A;  4MCC A;  3ILK A;  2EGV A;  4JWF A;  4YQ4 A;  4FMW A;  3OII A;  4X3L A;  4YQG A;  1TO0 A;  3L8U A;  4JWJ A;  2I6D A;  4CNF A;  4RG1 A;  3BBD A;  4YVG A;  1P9P A;  4YQ3 A;  4YQJ A;  5D9F A;  3OIJ A;  2Z0Y A;  4JWG A;  4YQK A;  3O7B A;  4JWH A;  1GZ0 A;  4YQA A;  1UAJ A;  4YQ5 A;  4YVJ A;  4YVI A;  4YQ2 A;  4CND A;  3IC6 A;  3E5Y A;  4FAK A;  4CNE A;  3QUV A;  1VH0 A;  4YPZ A;  5GMB A;  4YQR A;  1Z85 A;  3DCM X;  4E8B A;  4IG6 A;  3IEF A;  1NS5 A;  2HA8 A;  4YPW A;  1IPA A;  1ZJR A;  4KDZ A;  4YQ9 A;  1UAK A;  4PZK A;  4YQD A;  4YQO A;  4YQQ A;  1VHK A;  4XBO A;  2V3K A;  2O3A A;  3AI9 X;  2QWV A;  1V6Z A;  4MCB A;  3AIA A;  5GM8 A;  1J85 A;  4J3C A;  4YQ6 A;  1O6D A;  4YQS A;  5FAI A;  3NK7 A;  1V2X A;  1X7O A;  4L69 A;  1X7P A;  3AXZ A;  3KW2 A;  4H3Y A;  2EGW A;  4YQ0 A;  5CO4 A;  4YQB A;  4YQP A;  4YQL A;  4H3Z A;  3KY7 A;  3KTY A;  4YVH A;  4YQ8 A;  2CX8 A;  4KGN A;  4YQT A;  3N4J A;  3BBH A;  3OIN A;  4JAK A;  4YQ7 A;  4YQN A; 
#chains in the Genus database with same CATH homology
 4MCD A;  3NK6 A;  4CNG A;  2QMM A;  1NXZ A;  3KNU A;  3GYQ A;  3BBE A;  3N4K A;  4YQC A;  4YVK A;  1MXI A;  4JAL A;  1UAM A;  1K3R A;  1UAL A;  4YQI A;  2V3J A;  4YPX A;  3ONP A;  1OY5 A;  5GMC A;  4YQ1 A;  4YPY A;  1VHY A;  4X3M A;  2YY8 A;  4MCC A;  3ILK A;  2EGV A;  4JWF A;  4YQ4 A;  4FMW A;  3OII A;  4X3L A;  4YQG A;  1TO0 A;  3L8U A;  4JWJ A;  2I6D A;  4CNF A;  4RG1 A;  3BBD A;  4YVG A;  1P9P A;  4YQ3 A;  4YQJ A;  5D9F A;  3OIJ A;  2Z0Y A;  4JWG A;  4YQK A;  3O7B A;  4JWH A;  1GZ0 A;  4YQA A;  1UAJ A;  4YQ5 A;  4YVJ A;  4YVI A;  4YQ2 A;  4CND A;  3IC6 A;  3E5Y A;  4FAK A;  4CNE A;  3QUV A;  1VH0 A;  4YPZ A;  5GMB A;  4YQR A;  1Z85 A;  3DCM X;  4E8B A;  4IG6 A;  3IEF A;  1NS5 A;  2HA8 A;  4YPW A;  1IPA A;  1ZJR A;  4KDZ A;  4YQ9 A;  1UAK A;  4PZK A;  4YQD A;  4YQO A;  4YQQ A;  1VHK A;  4XBO A;  2V3K A;  2O3A A;  3AI9 X;  2QWV A;  1V6Z A;  4MCB A;  3AIA A;  5GM8 A;  1J85 A;  4J3C A;  4YQ6 A;  1O6D A;  4YQS A;  5FAI A;  3NK7 A;  1V2X A;  1X7O A;  4L69 A;  1X7P A;  3AXZ A;  3KW2 A;  4H3Y A;  2EGW A;  4YQ0 A;  5CO4 A;  4YQB A;  4YQP A;  4YQL A;  4H3Z A;  3KY7 A;  3KTY A;  4YVH A;  4YQ8 A;  2CX8 A;  4KGN A;  4YQT A;  3N4J A;  3BBH A;  3OIN A;  4JAK A;  4YQ7 A;  4YQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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