2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
b'MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4PZKA 4X3MA 2I6DA 1VH0A 2EGVA 4JALA 3OIIA 4YPWA 3O7BA 3KW2A 4RG1A 4MCCA 1GZ0A 4YQ7A 3L8UA 4YQ1A 3IEFA 4YQGA 4X3LA 4YVGA 1OY5A 3GYQA 3IC6A 4YQDA 4MCBA 3NK7A 4L69A 5GMBA 1VHYA 2O3AA 1J85A 1NXZA 4KGNA 1TO0A 3OIJA 1V2XA 3KNUA 3E5YA 5CO4A 1UAJA 1X7OA 4YQTA 4YPZA 4YQLA 4FAKA 1V6ZA 4YQ4A 4CNEA 1ZJRA 4YQ6A 3NK6A 4YQIA 3OINA 4YVHA 2V3JA 1UAMA 2HA8A 4YQRA 4YQQA 4YQPA 4YQ0A 4YQKA 3ONPA 2NWAA 2YY8A 4YVKA 1UAKA 4H3ZA 5FAIA 3N4KA 3KY7A 4YVIA 4YQ9A 2QWVA 4YQ5A 3AXZA 4J3CA 1Z85A 2V3KA 1O6DA 4H3YA 4YQBA 4YQCA 5GMCA 4CNGA 4YVJA 3BBDA 1P9PA 4YPYA 4YPXA 5GM8A 4YQ2A 4YQAA 4YQ3A 2EGWA 3QUVA 3BBHA 3AI9X 3AIAA 1K3RA 4CNFA 4XBOA 3N4JA 1NS5A 1MXIA 2CX8A 2QMMA 3ILKA 1IPAA 4CNDA 4YQSA 3DCMX 1X7PA 3BBEA 1VHKA 4YQJA 2Z0YA 4YQNA 4YQ8A 4MCDA 4IG6A 4KDZA 4YQOA 3KTYA 5D9FA 4E8BA 4JAKA 1UALA
chains in the Genus database with same CATH superfamily
4PZKA 4WF9S 3J7ZV 1FEUA 1VH0A 2EGVA 1O0CA 2I6DA 4X3MA 5GAEW 4JALA 4WCES 3OIIA 4YPWA 1EUYA 4WFAS 1GTSA 3O7BA 5GAGW 3KW2A 4RG1A 4MCCA 4H3SA 1GZ0A 4YQ7A 4H4KA 1EUQA 3CF5S 4V194 3L8UA 2AE0X 2G5DA 4YQ1A 5GAHW 3IEFA 4YQGA 4X3LA 4YVGA 1OY5A 3GYQA 4WFBS 3IC6A 1ZJWA 4YQDA 1EXDA 4MCBA 3NK7A 4L69A 2RE8A 3X1LB 5GMBA 3W2WB 1VHYA 2O3AA 1J85A 1DFUP 4P2BA 1NXZA 4KGNA 5JVHS 2GAEA 2ZJRS 1TO0A 4JWHA 4JWGA 3OIJA 1V2XA 3KNUA 3E5YA 1QRUA 4JXZA 5CO4A 3PIOS 1QRTA 1UAJA 2RD2A 5HL7S 1X7OA 4YQTA 5DM7S 5GADW 4YPZA 4YQLA 4FAKA 1O0BA 1V6ZA 2HZ7A 4CNEA 4YQ4A 2PICA 1ZJRA 4YQ6A 3NK6A 4YQIA 5IZNA 3OINA 4YVHA 4JWFA 3CZBA 2V3JA 5BNZA 2G6GA 1UAMA 2HA8A 4YQRA 1B75A 4YQQA 1QRSA 4IOCS 2PNWA 4YQPA 4YQ0A 4YQKA 3ONPA 2NWAA 2YY8A 4YVKA 2ZJPS 4UY88 1UAKA 4WFNS 4H3ZA 4FMWA 5FAIA 3N4KA 1QTQA 3KY7A 4YVIA 4YQ9A 5DM6S 2ZJQS 2QWVA 4YQ5A 3AXZA 4J3CA 4JWJA 3W2VB 1Z85A 2V3KA 4U67S 1O6DA 4H3YA 4YQBA 1D6KA 4YQCA 3PIPS 5GMCA 4IO9S 2PI8A 4CNGA 4YVJA 3BBDA 1P9PA 5JVGS 4YPYA 4YPXA 5GM8A 4YQ2A 4YQAA 4YQ3A 2EGWA 3BBHA 3QUVA 3AI9X 3AIAA 1K3RA 3AIIA 4CNFA 4JXXA 4XBOA 3N4JA 1NS5A 1MXIA 2CX8A 2QMMA 3ILKA 1IPAA 4CNDA 4JYZA 1UDXA 4YQSA 3DCMX 1X7PA 2PJJA 1NYLA 3BBEA 1VHKA 4YQJA 2Z0YA 4YQNA 4YQ8A 4MCDA 1GTRA 4IG6A 4KDZA 4IOAS 4YQOA 3KTYA 3DLLS 5D9FA 4E8BA 4JAKA 1UALA
chains in the Genus database with same CATH topology
4PZKA 4X3MA 2I6DA 1VH0A 2EGVA 4JALA 3OIIA 4YPWA 3O7BA 3KW2A 4RG1A 4MCCA 1GZ0A 4YQ7A 3L8UA 4YQ1A 3IEFA 4YQGA 4X3LA 4YVGA 1OY5A 3GYQA 3IC6A 4YQDA 4MCBA 3NK7A 4L69A 5GMBA 1VHYA 2O3AA 1J85A 1NXZA 4KGNA 1TO0A 4JWHA 4JWGA 3OIJA 1V2XA 3KNUA 3E5YA 5CO4A 1UAJA 1X7OA 4YQTA 4YPZA 4YQLA 4FAKA 1V6ZA 4YQ4A 4CNEA 1ZJRA 4YQ6A 3NK6A 4YQIA 3OINA 4YVHA 4JWFA 2V3JA 1UAMA 2HA8A 4YQRA 4YQQA 4YQPA 4YQ0A 4YQKA 3ONPA 2NWAA 2YY8A 4YVKA 1UAKA 4H3ZA 4FMWA 5FAIA 3N4KA 3KY7A 4YVIA 4YQ9A 2QWVA 4YQ5A 3AXZA 4J3CA 4JWJA 1Z85A 2V3KA 1O6DA 4H3YA 4YQBA 4YQCA 5GMCA 4CNGA 4YVJA 3BBDA 1P9PA 4YPYA 4YPXA 5GM8A 4YQ2A 4YQAA 4YQ3A 2EGWA 3QUVA 3BBHA 3AI9X 3AIAA 1K3RA 4CNFA 4XBOA 3N4JA 1NS5A 1MXIA 2CX8A 2QMMA 3ILKA 1IPAA 4CNDA 4YQSA 3DCMX 1X7PA 3BBEA 1VHKA 4YQJA 2Z0YA 4YQNA 4YQ8A 4MCDA 4IG6A 4KDZA 4YQOA 3KTYA 5D9FA 4E8BA 4JAKA 1UALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PZK A;  4X3M A;  2I6D A;  1VH0 A;  2EGV A;  4JAL A;  3OII A;  4YPW A;  3O7B A;  3KW2 A;  4RG1 A;  4MCC A;  1GZ0 A;  4YQ7 A;  3L8U A;  4YQ1 A;  3IEF A;  4YQG A;  4X3L A;  4YVG A;  1OY5 A;  3GYQ A;  3IC6 A;  4YQD A;  4MCB A;  3NK7 A;  4L69 A;  5GMB A;  1VHY A;  2O3A A;  1J85 A;  1NXZ A;  4KGN A;  1TO0 A;  3OIJ A;  1V2X A;  3KNU A;  3E5Y A;  5CO4 A;  1UAJ A;  1X7O A;  4YQT A;  4YPZ A;  4YQL A;  4FAK A;  1V6Z A;  4YQ4 A;  4CNE A;  1ZJR A;  4YQ6 A;  3NK6 A;  4YQI A;  3OIN A;  4YVH A;  2V3J A;  1UAM A;  2HA8 A;  4YQR A;  4YQQ A;  4YQP A;  4YQ0 A;  4YQK A;  3ONP A;  2NWA A;  2YY8 A;  4YVK A;  1UAK A;  4H3Z A;  5FAI A;  3N4K A;  3KY7 A;  4YVI A;  4YQ9 A;  2QWV A;  4YQ5 A;  3AXZ A;  4J3C A;  1Z85 A;  2V3K A;  1O6D A;  4H3Y A;  4YQB A;  4YQC A;  5GMC A;  4CNG A;  4YVJ A;  3BBD A;  1P9P A;  4YPY A;  4YPX A;  5GM8 A;  4YQ2 A;  4YQA A;  4YQ3 A;  2EGW A;  3QUV A;  3BBH A;  3AI9 X;  3AIA A;  1K3R A;  4CNF A;  4XBO A;  3N4J A;  1NS5 A;  1MXI A;  2CX8 A;  2QMM A;  3ILK A;  1IPA A;  4CND A;  4YQS A;  3DCM X;  1X7P A;  3BBE A;  1VHK A;  4YQJ A;  2Z0Y A;  4YQN A;  4YQ8 A;  4MCD A;  4IG6 A;  4KDZ A;  4YQO A;  3KTY A;  5D9F A;  4E8B A;  4JAK A;  1UAL A; 
#chains in the Genus database with same CATH topology
 4PZK A;  4WF9 S;  3J7Z V;  1FEU A;  1VH0 A;  2EGV A;  1O0C A;  2I6D A;  4X3M A;  5GAE W;  4JAL A;  4WCE S;  3OII A;  4YPW A;  1EUY A;  4WFA S;  1GTS A;  3O7B A;  5GAG W;  3KW2 A;  4RG1 A;  4MCC A;  4H3S A;  1GZ0 A;  4YQ7 A;  4H4K A;  1EUQ A;  3CF5 S;  4V19 4;  3L8U A;  2AE0 X;  2G5D A;  4YQ1 A;  5GAH W;  3IEF A;  4YQG A;  4X3L A;  4YVG A;  1OY5 A;  3GYQ A;  4WFB S;  3IC6 A;  1ZJW A;  4YQD A;  1EXD A;  4MCB A;  3NK7 A;  4L69 A;  2RE8 A;  3X1L B;  5GMB A;  3W2W B;  1VHY A;  2O3A A;  1J85 A;  1DFU P;  4P2B A;  1NXZ A;  4KGN A;  5JVH S;  2GAE A;  2ZJR S;  1TO0 A;  4JWH A;  4JWG A;  3OIJ A;  1V2X A;  3KNU A;  3E5Y A;  1QRU A;  4JXZ A;  5CO4 A;  3PIO S;  1QRT A;  1UAJ A;  2RD2 A;  5HL7 S;  1X7O A;  4YQT A;  5DM7 S;  5GAD W;  4YPZ A;  4YQL A;  4FAK A;  1O0B A;  1V6Z A;  2HZ7 A;  4CNE A;  4YQ4 A;  2PIC A;  1ZJR A;  4YQ6 A;  3NK6 A;  4YQI A;  5IZN A;  3OIN A;  4YVH A;  4JWF A;  3CZB A;  2V3J A;  5BNZ A;  2G6G A;  1UAM A;  2HA8 A;  4YQR A;  1B75 A;  4YQQ A;  1QRS A;  4IOC S;  2PNW A;  4YQP A;  4YQ0 A;  4YQK A;  3ONP A;  2NWA A;  2YY8 A;  4YVK A;  2ZJP S;  4UY8 8;  1UAK A;  4WFN S;  4H3Z A;  4FMW A;  5FAI A;  3N4K A;  1QTQ A;  3KY7 A;  4YVI A;  4YQ9 A;  5DM6 S;  2ZJQ S;  2QWV A;  4YQ5 A;  3AXZ A;  4J3C A;  4JWJ A;  3W2V B;  1Z85 A;  2V3K A;  4U67 S;  1O6D A;  4H3Y A;  4YQB A;  1D6K A;  4YQC A;  3PIP S;  5GMC A;  4IO9 S;  2PI8 A;  4CNG A;  4YVJ A;  3BBD A;  1P9P A;  5JVG S;  4YPY A;  4YPX A;  5GM8 A;  4YQ2 A;  4YQA A;  4YQ3 A;  2EGW A;  3BBH A;  3QUV A;  3AI9 X;  3AIA A;  1K3R A;  3AII A;  4CNF A;  4JXX A;  4XBO A;  3N4J A;  1NS5 A;  1MXI A;  2CX8 A;  2QMM A;  3ILK A;  1IPA A;  4CND A;  4JYZ A;  1UDX A;  4YQS A;  3DCM X;  1X7P A;  2PJJ A;  1NYL A;  3BBE A;  1VHK A;  4YQJ A;  2Z0Y A;  4YQN A;  4YQ8 A;  4MCD A;  1GTR A;  4IG6 A;  4KDZ A;  4IOA S;  4YQO A;  3KTY A;  3DLL S;  5D9F A;  4E8B A;  4JAK A;  1UAL A; 
#chains in the Genus database with same CATH homology
 4PZK A;  4X3M A;  2I6D A;  1VH0 A;  2EGV A;  4JAL A;  3OII A;  4YPW A;  3O7B A;  3KW2 A;  4RG1 A;  4MCC A;  1GZ0 A;  4YQ7 A;  3L8U A;  4YQ1 A;  3IEF A;  4YQG A;  4X3L A;  4YVG A;  1OY5 A;  3GYQ A;  3IC6 A;  4YQD A;  4MCB A;  3NK7 A;  4L69 A;  5GMB A;  1VHY A;  2O3A A;  1J85 A;  1NXZ A;  4KGN A;  1TO0 A;  4JWH A;  4JWG A;  3OIJ A;  1V2X A;  3KNU A;  3E5Y A;  5CO4 A;  1UAJ A;  1X7O A;  4YQT A;  4YPZ A;  4YQL A;  4FAK A;  1V6Z A;  4YQ4 A;  4CNE A;  1ZJR A;  4YQ6 A;  3NK6 A;  4YQI A;  3OIN A;  4YVH A;  4JWF A;  2V3J A;  1UAM A;  2HA8 A;  4YQR A;  4YQQ A;  4YQP A;  4YQ0 A;  4YQK A;  3ONP A;  2NWA A;  2YY8 A;  4YVK A;  1UAK A;  4H3Z A;  4FMW A;  5FAI A;  3N4K A;  3KY7 A;  4YVI A;  4YQ9 A;  2QWV A;  4YQ5 A;  3AXZ A;  4J3C A;  4JWJ A;  1Z85 A;  2V3K A;  1O6D A;  4H3Y A;  4YQB A;  4YQC A;  5GMC A;  4CNG A;  4YVJ A;  3BBD A;  1P9P A;  4YPY A;  4YPX A;  5GM8 A;  4YQ2 A;  4YQA A;  4YQ3 A;  2EGW A;  3QUV A;  3BBH A;  3AI9 X;  3AIA A;  1K3R A;  4CNF A;  4XBO A;  3N4J A;  1NS5 A;  1MXI A;  2CX8 A;  2QMM A;  3ILK A;  1IPA A;  4CND A;  4YQS A;  3DCM X;  1X7P A;  3BBE A;  1VHK A;  4YQJ A;  2Z0Y A;  4YQN A;  4YQ8 A;  4MCD A;  4IG6 A;  4KDZ A;  4YQO A;  3KTY A;  5D9F A;  4E8B A;  4JAK A;  1UAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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