2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
molecule keywords UPF0088 protein aq_165
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
2I6DA 4J3CA 1IPAA 3DCMX 1V6ZA 4X3LA 3NK6A 5FAIA 3N4KA 4YQTA 1VH0A 4YQ3A 3OINA 1ZJRA 3ONPA 4KDZA 4L69A 1UALA 1X7PA 1NS5A 1J85A 4YQSA 4YVJA 4FAKA 4YQBA 3QUVA 4YVHA 4JAKA 4YQQA 4YVIA 4XBOA 3GYQA 3OIIA 1NXZA 3E5YA 4CNGA 4MCCA 4X3MA 1VHKA 4YPZA 2Z0YA 1P9PA 4YQOA 4YQNA 4YPYA 4YQDA 3BBHA 4CNEA 3IC6A 4IG6A 2QWVA 4YQCA 4YQAA 4E8BA 2YY8A 5GMCA 3OIJA 5GMBA 5CO4A 3ILKA 2EGVA 4YQ8A 4YQGA 4YQ0A 4YQ5A 3AI9X 1X7OA 3BBDA 4MCDA 4PZKA 1V2XA 3AIAA 3O7BA 4YQJA 3KW2A 3AXZA 1GZ0A 4YQ6A 3L8UA 4YQ1A 1UAMA 1Z85A 2V3KA 3NK7A 4MCBA 4KGNA 4CNFA 4YQ2A 2O3AA 3IEFA 4YQRA 2HA8A 4YQPA 2EGWA 1UAKA 4H3YA 4H3ZA 4RG1A 4JALA 4YQKA 4YVKA 1VHYA 2CX8A 5GM8A 4YVGA 3KNUA 4CNDA 4YQ4A 5D9FA 4YPWA 2QMMA 2NWAA 3N4JA 1O6DA 4YQIA 3KTYA 4YQ9A 1TO0A 1OY5A 4YQLA 1MXIA 3KY7A 4YQ7A 1K3RA 4YPXA 3BBEA 2V3JA 1UAJA
chains in the Genus database with same CATH superfamily
2I6DA 4J3CA 1IPAA 1FEUA 3DCMX 1V6ZA 4X3LA 3NK6A 5FAIA 3N4KA 4YQTA 4IOCS 2PNWA 1VH0A 4YQ3A 3OINA 1ZJRA 5BNZA 3ONPA 4KDZA 1UDXA 4IO9S 4JYZA 1O0BA 5HL7S 4L69A 1UALA 1QRUA 1ZJWA 1NS5A 1X7PA 4FMWA 4H3SA 1J85A 4YQSA 4YVJA 4JXXA 1O0CA 4WFNS 4WFBS 5GADW 4YQBA 4FAKA 2PI8A 3QUVA 4JAKA 4YVHA 4YQQA 4YVIA 4XBOA 2PJJA 5JVHS 3GYQA 3OIIA 3W2VB 1NXZA 4WCES 3E5YA 1QRTA 4H4KA 4CNGA 4MCCA 4X3MA 1VHKA 4YPZA 2ZJRS 2Z0YA 1P9PA 4YQOA 1EUQA 4YPYA 4YQDA 4YQNA 4JWJA 3BBHA 1NYLA 4CNEA 3IC6A 5GAHW 4IG6A 2QWVA 4YQCA 1GTRA 4YQAA 4IOAS 4E8BA 2V3JA 2YY8A 2RD2A 5GMCA 1QTQA 1DFUP 5GMBA 3OIJA 5CO4A 3ILKA 2EGVA 4YQ8A 4YQGA 4YQ0A 5DM7S 4YQ5A 3AI9X 1X7OA 3PIOS 3DLLS 5IZNA 2HZ7A 3BBDA 4MCDA 4PZKA 2G6GA 1V2XA 2PICA 2ZJPS 3AIAA 2RE8A 3O7BA 4YQJA 3KW2A 2GAEA 3AXZA 1GZ0A 5GAGW 4YQ6A 3L8UA 5GAEW 4YQ1A 1UAMA 1B75A 1QRSA 1Z85A 3X1LB 4U67S 4JWHA 2V3KA 3NK7A 4MCBA 4KGNA 4UY88 4CNFA 4YQ2A 2O3AA 3IEFA 4YQRA 1EUYA 2HA8A 4YQPA 2G5DA 3CF5S 4JWGA 2EGWA 1UAKA 3PIPS 4H3YA 4JWFA 2AE0X 4H3ZA 4WF9S 4RG1A 1EXDA 3CZBA 3J7ZV 4JALA 4YQKA 4YVKA 1VHYA 2CX8A 4JXZA 5GM8A 4WFAS 4YVGA 4V194 3KNUA 4CNDA 4YQ4A 5D9FA 4YPWA 2QMMA 2NWAA 3N4JA 1O6DA 4YQIA 5DM6S 3KTYA 4YQ9A 1D6KA 1GTSA 1TO0A 1OY5A 5JVGS 4YQLA 1MXIA 3KY7A 4YQ7A 1K3RA 4P2BA 3AIIA 2ZJQS 4YPXA 3BBEA 3W2WB 1UAJA
chains in the Genus database with same CATH topology
2I6DA 4J3CA 1IPAA 3DCMX 1V6ZA 4X3LA 3NK6A 5FAIA 3N4KA 4YQTA 1VH0A 4YQ3A 3OINA 1ZJRA 3ONPA 4KDZA 4L69A 1UALA 1X7PA 1NS5A 4FMWA 1J85A 4YQSA 4YVJA 4FAKA 4YQBA 3QUVA 4YVHA 4JAKA 4YQQA 4YVIA 4XBOA 3GYQA 3OIIA 1NXZA 3E5YA 4CNGA 4MCCA 4X3MA 1VHKA 4YPZA 2Z0YA 1P9PA 4YQOA 4YQNA 4YPYA 4YQDA 4JWJA 3BBHA 4CNEA 3IC6A 4IG6A 2QWVA 4YQCA 4YQAA 4E8BA 2YY8A 5GMCA 3OIJA 5GMBA 5CO4A 3ILKA 2EGVA 4YQ8A 4YQGA 4YQ0A 4YQ5A 3AI9X 1X7OA 3BBDA 4MCDA 4PZKA 1V2XA 3AIAA 3O7BA 4YQJA 3KW2A 3AXZA 1GZ0A 4YQ6A 3L8UA 4YQ1A 1UAMA 1Z85A 4JWHA 2V3KA 3NK7A 4MCBA 4KGNA 4CNFA 4YQ2A 2O3AA 3IEFA 4YQRA 2HA8A 4YQPA 4JWGA 2EGWA 1UAKA 4H3YA 4JWFA 4H3ZA 4RG1A 4JALA 4YQKA 4YVKA 1VHYA 2CX8A 5GM8A 4YVGA 3KNUA 4CNDA 4YQ4A 5D9FA 4YPWA 2QMMA 2NWAA 3N4JA 1O6DA 4YQIA 3KTYA 4YQ9A 1TO0A 1OY5A 4YQLA 1MXIA 3KY7A 4YQ7A 1K3RA 4YPXA 3BBEA 2V3JA 1UAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I6D A;  4J3C A;  1IPA A;  3DCM X;  1V6Z A;  4X3L A;  3NK6 A;  5FAI A;  3N4K A;  4YQT A;  1VH0 A;  4YQ3 A;  3OIN A;  1ZJR A;  3ONP A;  4KDZ A;  4L69 A;  1UAL A;  1X7P A;  1NS5 A;  1J85 A;  4YQS A;  4YVJ A;  4FAK A;  4YQB A;  3QUV A;  4YVH A;  4JAK A;  4YQQ A;  4YVI A;  4XBO A;  3GYQ A;  3OII A;  1NXZ A;  3E5Y A;  4CNG A;  4MCC A;  4X3M A;  1VHK A;  4YPZ A;  2Z0Y A;  1P9P A;  4YQO A;  4YQN A;  4YPY A;  4YQD A;  3BBH A;  4CNE A;  3IC6 A;  4IG6 A;  2QWV A;  4YQC A;  4YQA A;  4E8B A;  2YY8 A;  5GMC A;  3OIJ A;  5GMB A;  5CO4 A;  3ILK A;  2EGV A;  4YQ8 A;  4YQG A;  4YQ0 A;  4YQ5 A;  3AI9 X;  1X7O A;  3BBD A;  4MCD A;  4PZK A;  1V2X A;  3AIA A;  3O7B A;  4YQJ A;  3KW2 A;  3AXZ A;  1GZ0 A;  4YQ6 A;  3L8U A;  4YQ1 A;  1UAM A;  1Z85 A;  2V3K A;  3NK7 A;  4MCB A;  4KGN A;  4CNF A;  4YQ2 A;  2O3A A;  3IEF A;  4YQR A;  2HA8 A;  4YQP A;  2EGW A;  1UAK A;  4H3Y A;  4H3Z A;  4RG1 A;  4JAL A;  4YQK A;  4YVK A;  1VHY A;  2CX8 A;  5GM8 A;  4YVG A;  3KNU A;  4CND A;  4YQ4 A;  5D9F A;  4YPW A;  2QMM A;  2NWA A;  3N4J A;  1O6D A;  4YQI A;  3KTY A;  4YQ9 A;  1TO0 A;  1OY5 A;  4YQL A;  1MXI A;  3KY7 A;  4YQ7 A;  1K3R A;  4YPX A;  3BBE A;  2V3J A;  1UAJ A; 
#chains in the Genus database with same CATH topology
 2I6D A;  4J3C A;  1IPA A;  1FEU A;  3DCM X;  1V6Z A;  4X3L A;  3NK6 A;  5FAI A;  3N4K A;  4YQT A;  4IOC S;  2PNW A;  1VH0 A;  4YQ3 A;  3OIN A;  1ZJR A;  5BNZ A;  3ONP A;  4KDZ A;  1UDX A;  4IO9 S;  4JYZ A;  1O0B A;  5HL7 S;  4L69 A;  1UAL A;  1QRU A;  1ZJW A;  1NS5 A;  1X7P A;  4FMW A;  4H3S A;  1J85 A;  4YQS A;  4YVJ A;  4JXX A;  1O0C A;  4WFN S;  4WFB S;  5GAD W;  4YQB A;  4FAK A;  2PI8 A;  3QUV A;  4JAK A;  4YVH A;  4YQQ A;  4YVI A;  4XBO A;  2PJJ A;  5JVH S;  3GYQ A;  3OII A;  3W2V B;  1NXZ A;  4WCE S;  3E5Y A;  1QRT A;  4H4K A;  4CNG A;  4MCC A;  4X3M A;  1VHK A;  4YPZ A;  2ZJR S;  2Z0Y A;  1P9P A;  4YQO A;  1EUQ A;  4YPY A;  4YQD A;  4YQN A;  4JWJ A;  3BBH A;  1NYL A;  4CNE A;  3IC6 A;  5GAH W;  4IG6 A;  2QWV A;  4YQC A;  1GTR A;  4YQA A;  4IOA S;  4E8B A;  2V3J A;  2YY8 A;  2RD2 A;  5GMC A;  1QTQ A;  1DFU P;  5GMB A;  3OIJ A;  5CO4 A;  3ILK A;  2EGV A;  4YQ8 A;  4YQG A;  4YQ0 A;  5DM7 S;  4YQ5 A;  3AI9 X;  1X7O A;  3PIO S;  3DLL S;  5IZN A;  2HZ7 A;  3BBD A;  4MCD A;  4PZK A;  2G6G A;  1V2X A;  2PIC A;  2ZJP S;  3AIA A;  2RE8 A;  3O7B A;  4YQJ A;  3KW2 A;  2GAE A;  3AXZ A;  1GZ0 A;  5GAG W;  4YQ6 A;  3L8U A;  5GAE W;  4YQ1 A;  1UAM A;  1B75 A;  1QRS A;  1Z85 A;  3X1L B;  4U67 S;  4JWH A;  2V3K A;  3NK7 A;  4MCB A;  4KGN A;  4UY8 8;  4CNF A;  4YQ2 A;  2O3A A;  3IEF A;  4YQR A;  1EUY A;  2HA8 A;  4YQP A;  2G5D A;  3CF5 S;  4JWG A;  2EGW A;  1UAK A;  3PIP S;  4H3Y A;  4JWF A;  2AE0 X;  4H3Z A;  4WF9 S;  4RG1 A;  1EXD A;  3CZB A;  3J7Z V;  4JAL A;  4YQK A;  4YVK A;  1VHY A;  2CX8 A;  4JXZ A;  5GM8 A;  4WFA S;  4YVG A;  4V19 4;  3KNU A;  4CND A;  4YQ4 A;  5D9F A;  4YPW A;  2QMM A;  2NWA A;  3N4J A;  1O6D A;  4YQI A;  5DM6 S;  3KTY A;  4YQ9 A;  1D6K A;  1GTS A;  1TO0 A;  1OY5 A;  5JVG S;  4YQL A;  1MXI A;  3KY7 A;  4YQ7 A;  1K3R A;  4P2B A;  3AII A;  2ZJQ S;  4YPX A;  3BBE A;  3W2W B;  1UAJ A; 
#chains in the Genus database with same CATH homology
 2I6D A;  4J3C A;  1IPA A;  3DCM X;  1V6Z A;  4X3L A;  3NK6 A;  5FAI A;  3N4K A;  4YQT A;  1VH0 A;  4YQ3 A;  3OIN A;  1ZJR A;  3ONP A;  4KDZ A;  4L69 A;  1UAL A;  1X7P A;  1NS5 A;  4FMW A;  1J85 A;  4YQS A;  4YVJ A;  4FAK A;  4YQB A;  3QUV A;  4YVH A;  4JAK A;  4YQQ A;  4YVI A;  4XBO A;  3GYQ A;  3OII A;  1NXZ A;  3E5Y A;  4CNG A;  4MCC A;  4X3M A;  1VHK A;  4YPZ A;  2Z0Y A;  1P9P A;  4YQO A;  4YQN A;  4YPY A;  4YQD A;  4JWJ A;  3BBH A;  4CNE A;  3IC6 A;  4IG6 A;  2QWV A;  4YQC A;  4YQA A;  4E8B A;  2YY8 A;  5GMC A;  3OIJ A;  5GMB A;  5CO4 A;  3ILK A;  2EGV A;  4YQ8 A;  4YQG A;  4YQ0 A;  4YQ5 A;  3AI9 X;  1X7O A;  3BBD A;  4MCD A;  4PZK A;  1V2X A;  3AIA A;  3O7B A;  4YQJ A;  3KW2 A;  3AXZ A;  1GZ0 A;  4YQ6 A;  3L8U A;  4YQ1 A;  1UAM A;  1Z85 A;  4JWH A;  2V3K A;  3NK7 A;  4MCB A;  4KGN A;  4CNF A;  4YQ2 A;  2O3A A;  3IEF A;  4YQR A;  2HA8 A;  4YQP A;  4JWG A;  2EGW A;  1UAK A;  4H3Y A;  4JWF A;  4H3Z A;  4RG1 A;  4JAL A;  4YQK A;  4YVK A;  1VHY A;  2CX8 A;  5GM8 A;  4YVG A;  3KNU A;  4CND A;  4YQ4 A;  5D9F A;  4YPW A;  2QMM A;  2NWA A;  3N4J A;  1O6D A;  4YQI A;  3KTY A;  4YQ9 A;  1TO0 A;  1OY5 A;  4YQL A;  1MXI A;  3KY7 A;  4YQ7 A;  1K3R A;  4YPX A;  3BBE A;  2V3J A;  1UAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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