2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Rna methyltransferase
molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
source organism Aquifex aeolicus
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4YQ4A 4YQCA 2Z0YA 3GYQA 5GMCA 4YQQA 4X3LA 3BBHA 1UALA 4YQ6A 3N4KA 4YQ9A 1GZ0A 2V3KA 4YQPA 1ZJRA 4MCCA 3ONPA 3NK6A 1MXIA 2EGWA 1NS5A 5D9FA 5FAIA 4YVHA 4YQNA 1VHYA 4JALA 2EGVA 3AIAA 4YQBA 4CNDA 4CNGA 4YPZA 3KNUA 4YQ7A 2O3AA 5GM8A 2HA8A 5CO4A 4CNEA 4YVKA 3OINA 4H3YA 1X7OA 4H3ZA 4KDZA 4YQOA 3KW2A 2CX8A 4YQDA 3E5YA 1UAKA 4YQ0A 3ILKA 1V6ZA 3KY7A 4IG6A 4XBOA 4YQJA 1O6DA 3DCMX 4YPXA 4JAKA 4YQ3A 4PZKA 4YQKA 3KTYA 4YPYA 4E8BA 2NWAA 1Z85A 3L8UA 4YQIA 4J3CA 2QMMA 2I6DA 4YQ5A 4MCDA 4YQTA 4YVJA 3AI9X 4X3MA 1V2XA 4RG1A 4YQLA 4YQ1A 4MCBA 1IPAA 3BBDA 1UAJA 4YQSA 3O7BA 4YQRA 1VHKA 3AXZA 3N4JA 3OIIA 1J85A 4YQAA 3NK7A 4CNFA 1UAMA 4YQ2A 5GMBA 1X7PA 4YQ8A 3IEFA 1TO0A 3QUVA 4FAKA 4YVIA 1P9PA 1OY5A 1K3RA 4YVGA 3OIJA 1VH0A 1NXZA 4YQGA 2V3JA 4L69A 3BBEA 4KGNA 4YPWA 3IC6A 2YY8A 2QWVA
chains in the Genus database with same CATH superfamily
4YQ4A 4YQCA 2Z0YA 4WFBS 4WCES 3GYQA 5GMCA 4YQQA 4U67S 3BBHA 4X3LA 5JVHS 1UALA 2PICA 3X1LB 4YQ6A 3N4KA 4YQ9A 1GZ0A 2V3KA 4YQPA 5JVGS 1EUYA 1ZJRA 3ONPA 3NK6A 1D6KA 4MCCA 5DM6S 1MXIA 2EGWA 1NS5A 5D9FA 5FAIA 5BNZA 4YVHA 4FMWA 4YQNA 1O0CA 4IOCS 1VHYA 1QRSA 2EGVA 2YY8A 3AIAA 4JALA 4YQBA 4CNDA 4JWHA 4CNGA 4YPZA 3KNUA 4JYZA 4YQ7A 2O3AA 4H4KA 5GM8A 5GAGW 2HA8A 3CZBA 5CO4A 4CNEA 4YVKA 3OINA 4H3YA 1X7OA 3CF5S 4H3ZA 4KDZA 4P2BA 4YQOA 3KW2A 4H3SA 2G6GA 3PIPS 2CX8A 4IOAS 4YQDA 3E5YA 1UAKA 2ZJQS 4YQ0A 3ILKA 2HZ7A 1V6ZA 3KY7A 4JWGA 4IG6A 4XBOA 4YQJA 1GTSA 5HL7S 1O6DA 3DCMX 4YPXA 4JAKA 2RD2A 1GTRA 4YQ3A 1QTQA 4PZKA 1UDXA 4YQKA 5GAHW 3KTYA 4YPYA 4E8BA 4V194 1Z85A 2NWAA 3L8UA 4YQIA 4JWJA 4J3CA 2QMMA 2I6DA 4YQ5A 3J7ZV 1EXDA 1NYLA 4MCDA 4YQTA 3PIOS 4YVJA 1O0BA 3AI9X 4X3MA 1FEUA 1V2XA 5GAEW 4RG1A 4YQLA 4YQ1A 3W2VB 4MCBA 1IPAA 3BBDA 1UAJA 2RE8A 4YQSA 3O7BA 4YQRA 1VHKA 2PJJA 3AIIA 4JXXA 3AXZA 3N4JA 3OIIA 1J85A 4JXZA 4YQAA 1DFUP 3NK7A 4IO9S 2QWVA 4WFNS 4CNFA 1UAMA 4YQ2A 5GADW 1QRTA 5GMBA 2G5DA 1X7PA 5DM7S 2ZJRS 4WF9S 3IEFA 4YQ8A 1TO0A 4WFAS 3QUVA 2PI8A 2AE0X 2PNWA 4UY88 4FAKA 4YVIA 1P9PA 5IZNA 1QRUA 1OY5A 4JWFA 1K3RA 4YVGA 1B75A 3OIJA 2GAEA 1ZJWA 1VH0A 1NXZA 4YQGA 2V3JA 4L69A 3BBEA 4KGNA 3DLLS 3W2WB 4YPWA 3IC6A 1EUQA 2ZJPS
chains in the Genus database with same CATH topology
4YQ4A 4YQCA 2Z0YA 3GYQA 5GMCA 4YQQA 4X3LA 3BBHA 1UALA 4YQ6A 3N4KA 4YQ9A 1GZ0A 2V3KA 4YQPA 1ZJRA 4MCCA 3ONPA 3NK6A 1MXIA 2EGWA 1NS5A 5D9FA 5FAIA 4YVHA 4FMWA 4YQNA 1VHYA 4JALA 2EGVA 3AIAA 4YQBA 4CNDA 4JWHA 4CNGA 4YPZA 3KNUA 4YQ7A 2O3AA 5GM8A 2HA8A 5CO4A 4CNEA 4YVKA 3OINA 4H3YA 1X7OA 4H3ZA 4KDZA 4YQOA 3KW2A 2CX8A 4YQDA 3E5YA 1UAKA 4YQ0A 3ILKA 1V6ZA 3KY7A 4JWGA 4IG6A 4XBOA 4YQJA 1O6DA 3DCMX 4YPXA 4JAKA 4YQ3A 4PZKA 4YQKA 3KTYA 4YPYA 4E8BA 2NWAA 1Z85A 3L8UA 4YQIA 4JWJA 4J3CA 2QMMA 2I6DA 4YQ5A 4MCDA 4YQTA 4YVJA 3AI9X 4X3MA 1V2XA 4RG1A 4YQLA 4YQ1A 4MCBA 1IPAA 3BBDA 1UAJA 4YQSA 3O7BA 4YQRA 1VHKA 3AXZA 3N4JA 3OIIA 1J85A 4YQAA 3NK7A 4CNFA 1UAMA 4YQ2A 5GMBA 1X7PA 4YQ8A 3IEFA 1TO0A 3QUVA 4FAKA 4YVIA 1P9PA 1OY5A 4JWFA 1K3RA 4YVGA 3OIJA 1VH0A 1NXZA 4YQGA 2V3JA 4L69A 3BBEA 4KGNA 4YPWA 3IC6A 2YY8A 2QWVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ4 A;  4YQC A;  2Z0Y A;  3GYQ A;  5GMC A;  4YQQ A;  4X3L A;  3BBH A;  1UAL A;  4YQ6 A;  3N4K A;  4YQ9 A;  1GZ0 A;  2V3K A;  4YQP A;  1ZJR A;  4MCC A;  3ONP A;  3NK6 A;  1MXI A;  2EGW A;  1NS5 A;  5D9F A;  5FAI A;  4YVH A;  4YQN A;  1VHY A;  4JAL A;  2EGV A;  3AIA A;  4YQB A;  4CND A;  4CNG A;  4YPZ A;  3KNU A;  4YQ7 A;  2O3A A;  5GM8 A;  2HA8 A;  5CO4 A;  4CNE A;  4YVK A;  3OIN A;  4H3Y A;  1X7O A;  4H3Z A;  4KDZ A;  4YQO A;  3KW2 A;  2CX8 A;  4YQD A;  3E5Y A;  1UAK A;  4YQ0 A;  3ILK A;  1V6Z A;  3KY7 A;  4IG6 A;  4XBO A;  4YQJ A;  1O6D A;  3DCM X;  4YPX A;  4JAK A;  4YQ3 A;  4PZK A;  4YQK A;  3KTY A;  4YPY A;  4E8B A;  2NWA A;  1Z85 A;  3L8U A;  4YQI A;  4J3C A;  2QMM A;  2I6D A;  4YQ5 A;  4MCD A;  4YQT A;  4YVJ A;  3AI9 X;  4X3M A;  1V2X A;  4RG1 A;  4YQL A;  4YQ1 A;  4MCB A;  1IPA A;  3BBD A;  1UAJ A;  4YQS A;  3O7B A;  4YQR A;  1VHK A;  3AXZ A;  3N4J A;  3OII A;  1J85 A;  4YQA A;  3NK7 A;  4CNF A;  1UAM A;  4YQ2 A;  5GMB A;  1X7P A;  4YQ8 A;  3IEF A;  1TO0 A;  3QUV A;  4FAK A;  4YVI A;  1P9P A;  1OY5 A;  1K3R A;  4YVG A;  3OIJ A;  1VH0 A;  1NXZ A;  4YQG A;  2V3J A;  4L69 A;  3BBE A;  4KGN A;  4YPW A;  3IC6 A;  2YY8 A;  2QWV A; 
#chains in the Genus database with same CATH topology
 4YQ4 A;  4YQC A;  2Z0Y A;  4WFB S;  4WCE S;  3GYQ A;  5GMC A;  4YQQ A;  4U67 S;  3BBH A;  4X3L A;  5JVH S;  1UAL A;  2PIC A;  3X1L B;  4YQ6 A;  3N4K A;  4YQ9 A;  1GZ0 A;  2V3K A;  4YQP A;  5JVG S;  1EUY A;  1ZJR A;  3ONP A;  3NK6 A;  1D6K A;  4MCC A;  5DM6 S;  1MXI A;  2EGW A;  1NS5 A;  5D9F A;  5FAI A;  5BNZ A;  4YVH A;  4FMW A;  4YQN A;  1O0C A;  4IOC S;  1VHY A;  1QRS A;  2EGV A;  2YY8 A;  3AIA A;  4JAL A;  4YQB A;  4CND A;  4JWH A;  4CNG A;  4YPZ A;  3KNU A;  4JYZ A;  4YQ7 A;  2O3A A;  4H4K A;  5GM8 A;  5GAG W;  2HA8 A;  3CZB A;  5CO4 A;  4CNE A;  4YVK A;  3OIN A;  4H3Y A;  1X7O A;  3CF5 S;  4H3Z A;  4KDZ A;  4P2B A;  4YQO A;  3KW2 A;  4H3S A;  2G6G A;  3PIP S;  2CX8 A;  4IOA S;  4YQD A;  3E5Y A;  1UAK A;  2ZJQ S;  4YQ0 A;  3ILK A;  2HZ7 A;  1V6Z A;  3KY7 A;  4JWG A;  4IG6 A;  4XBO A;  4YQJ A;  1GTS A;  5HL7 S;  1O6D A;  3DCM X;  4YPX A;  4JAK A;  2RD2 A;  1GTR A;  4YQ3 A;  1QTQ A;  4PZK A;  1UDX A;  4YQK A;  5GAH W;  3KTY A;  4YPY A;  4E8B A;  4V19 4;  1Z85 A;  2NWA A;  3L8U A;  4YQI A;  4JWJ A;  4J3C A;  2QMM A;  2I6D A;  4YQ5 A;  3J7Z V;  1EXD A;  1NYL A;  4MCD A;  4YQT A;  3PIO S;  4YVJ A;  1O0B A;  3AI9 X;  4X3M A;  1FEU A;  1V2X A;  5GAE W;  4RG1 A;  4YQL A;  4YQ1 A;  3W2V B;  4MCB A;  1IPA A;  3BBD A;  1UAJ A;  2RE8 A;  4YQS A;  3O7B A;  4YQR A;  1VHK A;  2PJJ A;  3AII A;  4JXX A;  3AXZ A;  3N4J A;  3OII A;  1J85 A;  4JXZ A;  4YQA A;  1DFU P;  3NK7 A;  4IO9 S;  2QWV A;  4WFN S;  4CNF A;  1UAM A;  4YQ2 A;  5GAD W;  1QRT A;  5GMB A;  2G5D A;  1X7P A;  5DM7 S;  2ZJR S;  4WF9 S;  3IEF A;  4YQ8 A;  1TO0 A;  4WFA S;  3QUV A;  2PI8 A;  2AE0 X;  2PNW A;  4UY8 8;  4FAK A;  4YVI A;  1P9P A;  5IZN A;  1QRU A;  1OY5 A;  4JWF A;  1K3R A;  4YVG A;  1B75 A;  3OIJ A;  2GAE A;  1ZJW A;  1VH0 A;  1NXZ A;  4YQG A;  2V3J A;  4L69 A;  3BBE A;  4KGN A;  3DLL S;  3W2W B;  4YPW A;  3IC6 A;  1EUQ A;  2ZJP S; 
#chains in the Genus database with same CATH homology
 4YQ4 A;  4YQC A;  2Z0Y A;  3GYQ A;  5GMC A;  4YQQ A;  4X3L A;  3BBH A;  1UAL A;  4YQ6 A;  3N4K A;  4YQ9 A;  1GZ0 A;  2V3K A;  4YQP A;  1ZJR A;  4MCC A;  3ONP A;  3NK6 A;  1MXI A;  2EGW A;  1NS5 A;  5D9F A;  5FAI A;  4YVH A;  4FMW A;  4YQN A;  1VHY A;  4JAL A;  2EGV A;  3AIA A;  4YQB A;  4CND A;  4JWH A;  4CNG A;  4YPZ A;  3KNU A;  4YQ7 A;  2O3A A;  5GM8 A;  2HA8 A;  5CO4 A;  4CNE A;  4YVK A;  3OIN A;  4H3Y A;  1X7O A;  4H3Z A;  4KDZ A;  4YQO A;  3KW2 A;  2CX8 A;  4YQD A;  3E5Y A;  1UAK A;  4YQ0 A;  3ILK A;  1V6Z A;  3KY7 A;  4JWG A;  4IG6 A;  4XBO A;  4YQJ A;  1O6D A;  3DCM X;  4YPX A;  4JAK A;  4YQ3 A;  4PZK A;  4YQK A;  3KTY A;  4YPY A;  4E8B A;  2NWA A;  1Z85 A;  3L8U A;  4YQI A;  4JWJ A;  4J3C A;  2QMM A;  2I6D A;  4YQ5 A;  4MCD A;  4YQT A;  4YVJ A;  3AI9 X;  4X3M A;  1V2X A;  4RG1 A;  4YQL A;  4YQ1 A;  4MCB A;  1IPA A;  3BBD A;  1UAJ A;  4YQS A;  3O7B A;  4YQR A;  1VHK A;  3AXZ A;  3N4J A;  3OII A;  1J85 A;  4YQA A;  3NK7 A;  4CNF A;  1UAM A;  4YQ2 A;  5GMB A;  1X7P A;  4YQ8 A;  3IEF A;  1TO0 A;  3QUV A;  4FAK A;  4YVI A;  1P9P A;  1OY5 A;  4JWF A;  1K3R A;  4YVG A;  3OIJ A;  1VH0 A;  1NXZ A;  4YQG A;  2V3J A;  4L69 A;  3BBE A;  4KGN A;  4YPW A;  3IC6 A;  2YY8 A;  2QWV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...