2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
2QWVA 4YVGA 4YQKA 5GM8A 2QMMA 3IC6A 3O7BA 4YQRA 4PZKA 4J3CA 1K3RA 2V3JA 4MCDA 2YY8A 4XBOA 1X7PA 5GMCA 4YVJA 4MCBA 4YQOA 3ONPA 3L8UA 3OIIA 3KNUA 4YPWA 4YQ7A 4YQJA 1UALA 3AIAA 1VH0A 3BBHA 1UAKA 2EGWA 2EGVA 3OINA 4YQSA 2O3AA 4JAKA 1O6DA 2HA8A 2NWAA 4L69A 4X3LA 4CNDA 4YQ0A 4JALA 3KW2A 4YQIA 3E5YA 4YQNA 4IG6A 2Z0YA 1OY5A 1J85A 4YPZA 4YQTA 1UAMA 4CNGA 1Z85A 4YPXA 4YVIA 3AXZA 1IPAA 4YQ1A 1NS5A 1VHYA 4YQPA 3GYQA 1GZ0A 2I6DA 4YVKA 4YQ3A 3N4JA 4YQ5A 2CX8A 3IEFA 1ZJRA 4RG1A 3AI9X 4YQ6A 4H3ZA 3NK6A 4YPYA 5FAIA 4YQGA 4YQBA 2V3KA 5CO4A 3QUVA 3ILKA 3NK7A 4YQLA 4X3MA 4KGNA 4E8BA 1NXZA 1V6ZA 3KTYA 1UAJA 4YQQA 4YQ8A 1TO0A 4MCCA 4CNEA 4KDZA 1X7OA 1VHKA 4YQ4A 3DCMX 4YQDA 4YQAA 3OIJA 4FAKA 4YQ9A 3N4KA 3KY7A 5GMBA 4YVHA 1MXIA 4H3YA 5D9FA 4CNFA 3BBEA 1V2XA 4YQ2A 3BBDA 4YQCA 1P9PA
chains in the Genus database with same CATH superfamily
2QWVA 4YVGA 4YQKA 4WFNS 5GM8A 2QMMA 3IC6A 3O7BA 4YQRA 4WFAS 4PZKA 1GTSA 5HL7S 4J3CA 3W2WB 1K3RA 2V3JA 3W2VB 4MCDA 1GTRA 2YY8A 1X7PA 4XBOA 5GMCA 4YVJA 4MCBA 2ZJQS 4YQOA 3ONPA 3L8UA 4WF9S 1EXDA 3OIIA 1D6KA 3KNUA 5GADW 4YPWA 4JXZA 4YQ7A 4YQJA 1UALA 5GAHW 3AIAA 1QTQA 1VH0A 3BBHA 1UAKA 2EGWA 2EGVA 3OINA 4YQSA 2O3AA 4JAKA 1O6DA 2HA8A 2NWAA 2RD2A 5DM7S 2PJJA 4L69A 4X3LA 4CNDA 4JYZA 4YQ0A 5GAEW 3X1LB 4JALA 3KW2A 4U67S 4IOCS 2GAEA 4YQIA 3E5YA 1QRSA 4FMWA 4YQNA 4UY88 2HZ7A 4IG6A 2Z0YA 1OY5A 1J85A 4YPZA 4YQTA 1UAMA 4CNGA 1ZJWA 1Z85A 4YPXA 4YVIA 3PIPS 3AXZA 4JWHA 1IPAA 4H3SA 4YQ1A 1NS5A 1VHYA 4YQPA 1O0BA 4JWGA 1QRUA 1UDXA 3GYQA 1EUQA 4H4KA 1GZ0A 2I6DA 4YVKA 2PI8A 2G5DA 1EUYA 4YQ3A 3N4JA 1QRTA 4YQ5A 2CX8A 1B75A 1O0CA 3IEFA 5JVGS 1ZJRA 4RG1A 3AI9X 4YQ6A 2PNWA 4WCES 3NK6A 4H3ZA 4YPYA 5FAIA 4YQGA 2G6GA 4YQBA 2V3KA 4V194 5JVHS 5CO4A 3PIOS 4JXXA 1FEUA 5DM6S 3ILKA 3QUVA 3NK7A 4YQLA 4X3MA 4IOAS 4KGNA 4WFBS 4E8BA 1NXZA 3J7ZV 1V6ZA 3KTYA 1UAJA 4JWJA 4YQQA 4YQ8A 3AIIA 1NYLA 1TO0A 4MCCA 4CNEA 4KDZA 1X7OA 1VHKA 2ZJRS 3DCMX 4YQ4A 4YQDA 4YQAA 5BNZA 3CF5S 3OIJA 3DLLS 4FAKA 4IO9S 4YQ9A 2ZJPS 3CZBA 3N4KA 4JWFA 3KY7A 5GMBA 4YVHA 1MXIA 4P2BA 5IZNA 2RE8A 4H3YA 5D9FA 4CNFA 2PICA 3BBEA 1V2XA 4YQ2A 5GAGW 3BBDA 1DFUP 4YQCA 1P9PA 2AE0X
chains in the Genus database with same CATH topology
2QWVA 4YVGA 4YQKA 5GM8A 2QMMA 3IC6A 3O7BA 4YQRA 4PZKA 4J3CA 1K3RA 2V3JA 4MCDA 2YY8A 4XBOA 1X7PA 5GMCA 4YVJA 4MCBA 4YQOA 3ONPA 3L8UA 3OIIA 3KNUA 4YPWA 4YQ7A 4YQJA 1UALA 3AIAA 1VH0A 3BBHA 1UAKA 2EGWA 2EGVA 3OINA 4YQSA 2O3AA 4JAKA 1O6DA 2HA8A 2NWAA 4L69A 4X3LA 4CNDA 4YQ0A 4JALA 3KW2A 4YQIA 3E5YA 4FMWA 4YQNA 4IG6A 2Z0YA 1OY5A 1J85A 4YPZA 4YQTA 1UAMA 4CNGA 1Z85A 4YPXA 4YVIA 3AXZA 4JWHA 1IPAA 4YQ1A 1NS5A 1VHYA 4YQPA 4JWGA 3GYQA 1GZ0A 2I6DA 4YVKA 4YQ3A 3N4JA 4YQ5A 2CX8A 3IEFA 1ZJRA 4RG1A 3AI9X 4YQ6A 4H3ZA 3NK6A 4YPYA 5FAIA 4YQGA 4YQBA 2V3KA 5CO4A 3QUVA 3ILKA 3NK7A 4YQLA 4X3MA 4KGNA 4E8BA 1NXZA 1V6ZA 3KTYA 1UAJA 4JWJA 4YQQA 4YQ8A 1TO0A 4MCCA 4CNEA 4KDZA 1X7OA 1VHKA 4YQ4A 3DCMX 4YQDA 4YQAA 3OIJA 4FAKA 4YQ9A 3N4KA 4JWFA 3KY7A 5GMBA 4YVHA 1MXIA 4H3YA 5D9FA 4CNFA 3BBEA 1V2XA 4YQ2A 3BBDA 4YQCA 1P9PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QWV A;  4YVG A;  4YQK A;  5GM8 A;  2QMM A;  3IC6 A;  3O7B A;  4YQR A;  4PZK A;  4J3C A;  1K3R A;  2V3J A;  4MCD A;  2YY8 A;  4XBO A;  1X7P A;  5GMC A;  4YVJ A;  4MCB A;  4YQO A;  3ONP A;  3L8U A;  3OII A;  3KNU A;  4YPW A;  4YQ7 A;  4YQJ A;  1UAL A;  3AIA A;  1VH0 A;  3BBH A;  1UAK A;  2EGW A;  2EGV A;  3OIN A;  4YQS A;  2O3A A;  4JAK A;  1O6D A;  2HA8 A;  2NWA A;  4L69 A;  4X3L A;  4CND A;  4YQ0 A;  4JAL A;  3KW2 A;  4YQI A;  3E5Y A;  4YQN A;  4IG6 A;  2Z0Y A;  1OY5 A;  1J85 A;  4YPZ A;  4YQT A;  1UAM A;  4CNG A;  1Z85 A;  4YPX A;  4YVI A;  3AXZ A;  1IPA A;  4YQ1 A;  1NS5 A;  1VHY A;  4YQP A;  3GYQ A;  1GZ0 A;  2I6D A;  4YVK A;  4YQ3 A;  3N4J A;  4YQ5 A;  2CX8 A;  3IEF A;  1ZJR A;  4RG1 A;  3AI9 X;  4YQ6 A;  4H3Z A;  3NK6 A;  4YPY A;  5FAI A;  4YQG A;  4YQB A;  2V3K A;  5CO4 A;  3QUV A;  3ILK A;  3NK7 A;  4YQL A;  4X3M A;  4KGN A;  4E8B A;  1NXZ A;  1V6Z A;  3KTY A;  1UAJ A;  4YQQ A;  4YQ8 A;  1TO0 A;  4MCC A;  4CNE A;  4KDZ A;  1X7O A;  1VHK A;  4YQ4 A;  3DCM X;  4YQD A;  4YQA A;  3OIJ A;  4FAK A;  4YQ9 A;  3N4K A;  3KY7 A;  5GMB A;  4YVH A;  1MXI A;  4H3Y A;  5D9F A;  4CNF A;  3BBE A;  1V2X A;  4YQ2 A;  3BBD A;  4YQC A;  1P9P A; 
#chains in the Genus database with same CATH topology
 2QWV A;  4YVG A;  4YQK A;  4WFN S;  5GM8 A;  2QMM A;  3IC6 A;  3O7B A;  4YQR A;  4WFA S;  4PZK A;  1GTS A;  5HL7 S;  4J3C A;  3W2W B;  1K3R A;  2V3J A;  3W2V B;  4MCD A;  1GTR A;  2YY8 A;  1X7P A;  4XBO A;  5GMC A;  4YVJ A;  4MCB A;  2ZJQ S;  4YQO A;  3ONP A;  3L8U A;  4WF9 S;  1EXD A;  3OII A;  1D6K A;  3KNU A;  5GAD W;  4YPW A;  4JXZ A;  4YQ7 A;  4YQJ A;  1UAL A;  5GAH W;  3AIA A;  1QTQ A;  1VH0 A;  3BBH A;  1UAK A;  2EGW A;  2EGV A;  3OIN A;  4YQS A;  2O3A A;  4JAK A;  1O6D A;  2HA8 A;  2NWA A;  2RD2 A;  5DM7 S;  2PJJ A;  4L69 A;  4X3L A;  4CND A;  4JYZ A;  4YQ0 A;  5GAE W;  3X1L B;  4JAL A;  3KW2 A;  4U67 S;  4IOC S;  2GAE A;  4YQI A;  3E5Y A;  1QRS A;  4FMW A;  4YQN A;  4UY8 8;  2HZ7 A;  4IG6 A;  2Z0Y A;  1OY5 A;  1J85 A;  4YPZ A;  4YQT A;  1UAM A;  4CNG A;  1ZJW A;  1Z85 A;  4YPX A;  4YVI A;  3PIP S;  3AXZ A;  4JWH A;  1IPA A;  4H3S A;  4YQ1 A;  1NS5 A;  1VHY A;  4YQP A;  1O0B A;  4JWG A;  1QRU A;  1UDX A;  3GYQ A;  1EUQ A;  4H4K A;  1GZ0 A;  2I6D A;  4YVK A;  2PI8 A;  2G5D A;  1EUY A;  4YQ3 A;  3N4J A;  1QRT A;  4YQ5 A;  2CX8 A;  1B75 A;  1O0C A;  3IEF A;  5JVG S;  1ZJR A;  4RG1 A;  3AI9 X;  4YQ6 A;  2PNW A;  4WCE S;  3NK6 A;  4H3Z A;  4YPY A;  5FAI A;  4YQG A;  2G6G A;  4YQB A;  2V3K A;  4V19 4;  5JVH S;  5CO4 A;  3PIO S;  4JXX A;  1FEU A;  5DM6 S;  3ILK A;  3QUV A;  3NK7 A;  4YQL A;  4X3M A;  4IOA S;  4KGN A;  4WFB S;  4E8B A;  1NXZ A;  3J7Z V;  1V6Z A;  3KTY A;  1UAJ A;  4JWJ A;  4YQQ A;  4YQ8 A;  3AII A;  1NYL A;  1TO0 A;  4MCC A;  4CNE A;  4KDZ A;  1X7O A;  1VHK A;  2ZJR S;  3DCM X;  4YQ4 A;  4YQD A;  4YQA A;  5BNZ A;  3CF5 S;  3OIJ A;  3DLL S;  4FAK A;  4IO9 S;  4YQ9 A;  2ZJP S;  3CZB A;  3N4K A;  4JWF A;  3KY7 A;  5GMB A;  4YVH A;  1MXI A;  4P2B A;  5IZN A;  2RE8 A;  4H3Y A;  5D9F A;  4CNF A;  2PIC A;  3BBE A;  1V2X A;  4YQ2 A;  5GAG W;  3BBD A;  1DFU P;  4YQC A;  1P9P A;  2AE0 X; 
#chains in the Genus database with same CATH homology
 2QWV A;  4YVG A;  4YQK A;  5GM8 A;  2QMM A;  3IC6 A;  3O7B A;  4YQR A;  4PZK A;  4J3C A;  1K3R A;  2V3J A;  4MCD A;  2YY8 A;  4XBO A;  1X7P A;  5GMC A;  4YVJ A;  4MCB A;  4YQO A;  3ONP A;  3L8U A;  3OII A;  3KNU A;  4YPW A;  4YQ7 A;  4YQJ A;  1UAL A;  3AIA A;  1VH0 A;  3BBH A;  1UAK A;  2EGW A;  2EGV A;  3OIN A;  4YQS A;  2O3A A;  4JAK A;  1O6D A;  2HA8 A;  2NWA A;  4L69 A;  4X3L A;  4CND A;  4YQ0 A;  4JAL A;  3KW2 A;  4YQI A;  3E5Y A;  4FMW A;  4YQN A;  4IG6 A;  2Z0Y A;  1OY5 A;  1J85 A;  4YPZ A;  4YQT A;  1UAM A;  4CNG A;  1Z85 A;  4YPX A;  4YVI A;  3AXZ A;  4JWH A;  1IPA A;  4YQ1 A;  1NS5 A;  1VHY A;  4YQP A;  4JWG A;  3GYQ A;  1GZ0 A;  2I6D A;  4YVK A;  4YQ3 A;  3N4J A;  4YQ5 A;  2CX8 A;  3IEF A;  1ZJR A;  4RG1 A;  3AI9 X;  4YQ6 A;  4H3Z A;  3NK6 A;  4YPY A;  5FAI A;  4YQG A;  4YQB A;  2V3K A;  5CO4 A;  3QUV A;  3ILK A;  3NK7 A;  4YQL A;  4X3M A;  4KGN A;  4E8B A;  1NXZ A;  1V6Z A;  3KTY A;  1UAJ A;  4JWJ A;  4YQQ A;  4YQ8 A;  1TO0 A;  4MCC A;  4CNE A;  4KDZ A;  1X7O A;  1VHK A;  4YQ4 A;  3DCM X;  4YQD A;  4YQA A;  3OIJ A;  4FAK A;  4YQ9 A;  3N4K A;  4JWF A;  3KY7 A;  5GMB A;  4YVH A;  1MXI A;  4H3Y A;  5D9F A;  4CNF A;  3BBE A;  1V2X A;  4YQ2 A;  3BBD A;  4YQC A;  1P9P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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