2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
molecule keywords UPF0088 protein aq_165
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4H3ZA 2EGVA 4YQRA 1NS5A 4FAKA 4RG1A 1VHYA 4L69A 3OIIA 1J85A 2YY8A 3AI9X 4YQTA 4YQQA 4YVHA 3ONPA 2V3KA 1TO0A 1MXIA 4YQPA 5FAIA 3KTYA 3KY7A 5GMBA 3OINA 2Z0YA 4H3YA 3QUVA 1UAKA 3OIJA 4E8BA 3N4JA 3N4KA 4CNGA 4JAKA 4X3MA 5CO4A 2QWVA 4CNFA 1Z85A 4YVKA 4YQGA 2CX8A 4MCBA 2I6DA 3L8UA 4YQ2A 1VH0A 3NK6A 4YVIA 3GYQA 5GM8A 2NWAA 4YQIA 4JALA 4YQ1A 1UAJA 4J3CA 2EGWA 4X3LA 1IPAA 2QMMA 1X7OA 1UALA 4YQ9A 3IC6A 4CNEA 4YQ8A 1UAMA 4IG6A 4KGNA 3BBHA 4YQCA 4YQDA 1OY5A 1O6DA 3KNUA 3KW2A 4MCCA 3AXZA 4CNDA 4YPXA 3BBEA 4YQ7A 4YPZA 4YQBA 4YQ3A 4YQOA 1ZJRA 4YQ6A 4KDZA 3BBDA 1V2XA 4YVGA 4YQAA 4YQJA 1VHKA 4MCDA 4PZKA 1NXZA 2V3JA 4YQ5A 4YPWA 4YQ0A 1P9PA 2HA8A 5GMCA 1GZ0A 4YQKA 4YQNA 3E5YA 3AIAA 3O7BA 3DCMX 2O3AA 5D9FA 4YVJA 3NK7A 1K3RA 4XBOA 1X7PA 4YQ4A 4YQSA 3IEFA 1V6ZA 4YPYA 3ILKA 4YQLA
chains in the Genus database with same CATH superfamily
4H3ZA 3J7ZV 2EGVA 2GAEA 4YQRA 1NS5A 4FAKA 4RG1A 1VHYA 4L69A 2G6GA 5GAHW 3X1LB 4WFAS 3DLLS 3OIIA 1J85A 2YY8A 3AI9X 4JYZA 4YQTA 1B75A 4YQQA 4YVHA 1D6KA 3ONPA 1GTSA 2V3KA 2PI8A 1TO0A 1MXIA 5BNZA 4WF9S 4YQPA 5FAIA 5HL7S 4H3SA 3KTYA 3KY7A 5GMBA 4P2BA 5GADW 3OINA 1EUYA 2Z0YA 5DM6S 3W2VB 3QUVA 1UAKA 4H3YA 4E8BA 5GAGW 3OIJA 3N4JA 5DM7S 3N4KA 4CNGA 4JAKA 3AIIA 4X3MA 4JWFA 5CO4A 2QWVA 4CNFA 4WCES 1Z85A 4JWGA 4YQGA 4YVKA 2CX8A 4MCBA 2PJJA 2I6DA 4WFNS 4U67S 4JWHA 3L8UA 1QRUA 1QRSA 4YQ2A 1VH0A 2PNWA 3PIOS 3NK6A 4YVIA 3GYQA 5GM8A 2G5DA 2NWAA 4YQIA 4JALA 4JWJA 4FMWA 4YQ1A 1UAJA 2RE8A 4J3CA 2EGWA 4X3LA 5JVGS 2RD2A 1IPAA 2QMMA 1X7OA 1UALA 4YQ9A 3IC6A 1ZJWA 4IO9S 4JXXA 4CNEA 4YQ8A 1UAMA 4IG6A 4KGNA 3BBHA 4YQCA 4YQDA 4H4KA 1NYLA 1OY5A 4V194 1QTQA 2ZJQS 1O6DA 3KNUA 3KW2A 4MCCA 3AXZA 4CNDA 4YPXA 1O0BA 1UDXA 5IZNA 2ZJPS 2AE0X 2ZJRS 3BBEA 4YQNA 4IOCS 4YQ7A 4YPZA 4YQBA 4IOAS 4YQ3A 4YQOA 1ZJRA 3PIPS 2HZ7A 4KDZA 1GTRA 3BBDA 1V2XA 4YQ6A 3W2WB 1EUQA 4YVGA 1DFUP 4YQAA 4YQJA 1VHKA 4MCDA 4PZKA 1NXZA 3CF5S 2V3JA 4YQ5A 4YPWA 4YQ0A 5GAEW 1P9PA 2HA8A 1EXDA 5GMCA 2PICA 1QRTA 1O0CA 1GZ0A 4YQKA 1FEUA 3E5YA 3AIAA 3O7BA 3DCMX 2O3AA 5D9FA 4YVJA 3CZBA 4JXZA 3NK7A 1K3RA 4XBOA 1X7PA 4YQ4A 5JVHS 4YQSA 3IEFA 1V6ZA 4YPYA 3ILKA 4UY88 4WFBS 4YQLA
chains in the Genus database with same CATH topology
4H3ZA 2EGVA 4YQRA 1NS5A 4FAKA 4RG1A 1VHYA 4L69A 3OIIA 1J85A 2YY8A 3AI9X 4YQTA 4YQQA 4YVHA 3ONPA 2V3KA 1TO0A 1MXIA 4YQPA 5FAIA 3KTYA 3KY7A 5GMBA 3OINA 2Z0YA 4H3YA 3QUVA 1UAKA 3OIJA 4E8BA 3N4JA 3N4KA 4CNGA 4JAKA 4X3MA 5CO4A 2QWVA 4CNFA 4JWGA 1Z85A 4YVKA 4YQGA 2CX8A 4MCBA 2I6DA 4JWHA 3L8UA 4YQ2A 1VH0A 3NK6A 4YVIA 3GYQA 5GM8A 2NWAA 4YQIA 4JALA 4JWJA 4FMWA 4YQ1A 1UAJA 4J3CA 2EGWA 4X3LA 1IPAA 2QMMA 1X7OA 1UALA 4YQ9A 3IC6A 4CNEA 4YQ8A 1UAMA 4IG6A 4KGNA 3BBHA 4YQCA 4YQDA 1OY5A 1O6DA 3KNUA 3KW2A 4MCCA 3AXZA 4CNDA 4YPXA 3BBEA 4YQ7A 4YPZA 4YQBA 4YQ3A 4YQOA 1ZJRA 4YQ6A 4KDZA 3BBDA 1V2XA 4YVGA 4YQAA 4YQJA 1VHKA 4MCDA 4PZKA 1NXZA 2V3JA 4YQ5A 4YPWA 4YQ0A 1P9PA 2HA8A 5GMCA 1GZ0A 4YQKA 4YQNA 3E5YA 3AIAA 3O7BA 3DCMX 2O3AA 5D9FA 4YVJA 3NK7A 1K3RA 4XBOA 1X7PA 4YQ4A 4YQSA 3IEFA 1V6ZA 4YPYA 3ILKA 4JWFA 4YQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H3Z A;  2EGV A;  4YQR A;  1NS5 A;  4FAK A;  4RG1 A;  1VHY A;  4L69 A;  3OII A;  1J85 A;  2YY8 A;  3AI9 X;  4YQT A;  4YQQ A;  4YVH A;  3ONP A;  2V3K A;  1TO0 A;  1MXI A;  4YQP A;  5FAI A;  3KTY A;  3KY7 A;  5GMB A;  3OIN A;  2Z0Y A;  4H3Y A;  3QUV A;  1UAK A;  3OIJ A;  4E8B A;  3N4J A;  3N4K A;  4CNG A;  4JAK A;  4X3M A;  5CO4 A;  2QWV A;  4CNF A;  1Z85 A;  4YVK A;  4YQG A;  2CX8 A;  4MCB A;  2I6D A;  3L8U A;  4YQ2 A;  1VH0 A;  3NK6 A;  4YVI A;  3GYQ A;  5GM8 A;  2NWA A;  4YQI A;  4JAL A;  4YQ1 A;  1UAJ A;  4J3C A;  2EGW A;  4X3L A;  1IPA A;  2QMM A;  1X7O A;  1UAL A;  4YQ9 A;  3IC6 A;  4CNE A;  4YQ8 A;  1UAM A;  4IG6 A;  4KGN A;  3BBH A;  4YQC A;  4YQD A;  1OY5 A;  1O6D A;  3KNU A;  3KW2 A;  4MCC A;  3AXZ A;  4CND A;  4YPX A;  3BBE A;  4YQ7 A;  4YPZ A;  4YQB A;  4YQ3 A;  4YQO A;  1ZJR A;  4YQ6 A;  4KDZ A;  3BBD A;  1V2X A;  4YVG A;  4YQA A;  4YQJ A;  1VHK A;  4MCD A;  4PZK A;  1NXZ A;  2V3J A;  4YQ5 A;  4YPW A;  4YQ0 A;  1P9P A;  2HA8 A;  5GMC A;  1GZ0 A;  4YQK A;  4YQN A;  3E5Y A;  3AIA A;  3O7B A;  3DCM X;  2O3A A;  5D9F A;  4YVJ A;  3NK7 A;  1K3R A;  4XBO A;  1X7P A;  4YQ4 A;  4YQS A;  3IEF A;  1V6Z A;  4YPY A;  3ILK A;  4YQL A; 
#chains in the Genus database with same CATH topology
 4H3Z A;  3J7Z V;  2EGV A;  2GAE A;  4YQR A;  1NS5 A;  4FAK A;  4RG1 A;  1VHY A;  4L69 A;  2G6G A;  5GAH W;  3X1L B;  4WFA S;  3DLL S;  3OII A;  1J85 A;  2YY8 A;  3AI9 X;  4JYZ A;  4YQT A;  1B75 A;  4YQQ A;  4YVH A;  1D6K A;  3ONP A;  1GTS A;  2V3K A;  2PI8 A;  1TO0 A;  1MXI A;  5BNZ A;  4WF9 S;  4YQP A;  5FAI A;  5HL7 S;  4H3S A;  3KTY A;  3KY7 A;  5GMB A;  4P2B A;  5GAD W;  3OIN A;  1EUY A;  2Z0Y A;  5DM6 S;  3W2V B;  3QUV A;  1UAK A;  4H3Y A;  4E8B A;  5GAG W;  3OIJ A;  3N4J A;  5DM7 S;  3N4K A;  4CNG A;  4JAK A;  3AII A;  4X3M A;  4JWF A;  5CO4 A;  2QWV A;  4CNF A;  4WCE S;  1Z85 A;  4JWG A;  4YQG A;  4YVK A;  2CX8 A;  4MCB A;  2PJJ A;  2I6D A;  4WFN S;  4U67 S;  4JWH A;  3L8U A;  1QRU A;  1QRS A;  4YQ2 A;  1VH0 A;  2PNW A;  3PIO S;  3NK6 A;  4YVI A;  3GYQ A;  5GM8 A;  2G5D A;  2NWA A;  4YQI A;  4JAL A;  4JWJ A;  4FMW A;  4YQ1 A;  1UAJ A;  2RE8 A;  4J3C A;  2EGW A;  4X3L A;  5JVG S;  2RD2 A;  1IPA A;  2QMM A;  1X7O A;  1UAL A;  4YQ9 A;  3IC6 A;  1ZJW A;  4IO9 S;  4JXX A;  4CNE A;  4YQ8 A;  1UAM A;  4IG6 A;  4KGN A;  3BBH A;  4YQC A;  4YQD A;  4H4K A;  1NYL A;  1OY5 A;  4V19 4;  1QTQ A;  2ZJQ S;  1O6D A;  3KNU A;  3KW2 A;  4MCC A;  3AXZ A;  4CND A;  4YPX A;  1O0B A;  1UDX A;  5IZN A;  2ZJP S;  2AE0 X;  2ZJR S;  3BBE A;  4YQN A;  4IOC S;  4YQ7 A;  4YPZ A;  4YQB A;  4IOA S;  4YQ3 A;  4YQO A;  1ZJR A;  3PIP S;  2HZ7 A;  4KDZ A;  1GTR A;  3BBD A;  1V2X A;  4YQ6 A;  3W2W B;  1EUQ A;  4YVG A;  1DFU P;  4YQA A;  4YQJ A;  1VHK A;  4MCD A;  4PZK A;  1NXZ A;  3CF5 S;  2V3J A;  4YQ5 A;  4YPW A;  4YQ0 A;  5GAE W;  1P9P A;  2HA8 A;  1EXD A;  5GMC A;  2PIC A;  1QRT A;  1O0C A;  1GZ0 A;  4YQK A;  1FEU A;  3E5Y A;  3AIA A;  3O7B A;  3DCM X;  2O3A A;  5D9F A;  4YVJ A;  3CZB A;  4JXZ A;  3NK7 A;  1K3R A;  4XBO A;  1X7P A;  4YQ4 A;  5JVH S;  4YQS A;  3IEF A;  1V6Z A;  4YPY A;  3ILK A;  4UY8 8;  4WFB S;  4YQL A; 
#chains in the Genus database with same CATH homology
 4H3Z A;  2EGV A;  4YQR A;  1NS5 A;  4FAK A;  4RG1 A;  1VHY A;  4L69 A;  3OII A;  1J85 A;  2YY8 A;  3AI9 X;  4YQT A;  4YQQ A;  4YVH A;  3ONP A;  2V3K A;  1TO0 A;  1MXI A;  4YQP A;  5FAI A;  3KTY A;  3KY7 A;  5GMB A;  3OIN A;  2Z0Y A;  4H3Y A;  3QUV A;  1UAK A;  3OIJ A;  4E8B A;  3N4J A;  3N4K A;  4CNG A;  4JAK A;  4X3M A;  5CO4 A;  2QWV A;  4CNF A;  4JWG A;  1Z85 A;  4YVK A;  4YQG A;  2CX8 A;  4MCB A;  2I6D A;  4JWH A;  3L8U A;  4YQ2 A;  1VH0 A;  3NK6 A;  4YVI A;  3GYQ A;  5GM8 A;  2NWA A;  4YQI A;  4JAL A;  4JWJ A;  4FMW A;  4YQ1 A;  1UAJ A;  4J3C A;  2EGW A;  4X3L A;  1IPA A;  2QMM A;  1X7O A;  1UAL A;  4YQ9 A;  3IC6 A;  4CNE A;  4YQ8 A;  1UAM A;  4IG6 A;  4KGN A;  3BBH A;  4YQC A;  4YQD A;  1OY5 A;  1O6D A;  3KNU A;  3KW2 A;  4MCC A;  3AXZ A;  4CND A;  4YPX A;  3BBE A;  4YQ7 A;  4YPZ A;  4YQB A;  4YQ3 A;  4YQO A;  1ZJR A;  4YQ6 A;  4KDZ A;  3BBD A;  1V2X A;  4YVG A;  4YQA A;  4YQJ A;  1VHK A;  4MCD A;  4PZK A;  1NXZ A;  2V3J A;  4YQ5 A;  4YPW A;  4YQ0 A;  1P9P A;  2HA8 A;  5GMC A;  1GZ0 A;  4YQK A;  4YQN A;  3E5Y A;  3AIA A;  3O7B A;  3DCM X;  2O3A A;  5D9F A;  4YVJ A;  3NK7 A;  1K3R A;  4XBO A;  1X7P A;  4YQ4 A;  4YQS A;  3IEF A;  1V6Z A;  4YPY A;  3ILK A;  4JWF A;  4YQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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