2HA8A

Methyltransferase domain of human tar (hiv-1) rna binding protein 1
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
Knots found
sequence length
159
structure length
159
Chain Sequence
LGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWLPLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 in complex with S-adenosyl-L-homocystein.
rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords TAR (HIV-1) RNA loop binding protein
total genus 57
structure length 159
sequence length 159
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2006-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2ha8A01
3KW2A 4J3CA 1UALA 1ZJRA 4YQGA 2Z0YA 3IEFA 1UAJA 4YQ8A 4YQPA 4YQ5A 1NXZA 4YQ7A 4YQ6A 2EGWA 4CNGA 4KDZA 5GMBA 5CO4A 4YQKA 4IG6A 4YQAA 4JAKA 4YQNA 1VH0A 3DCMX 3BBDA 4YQQA 3BBEA 4YPYA 4YPXA 4YQ2A 4YQRA 3NK6A 5FAIA 5GM8A 4RG1A 4YQ4A 4YQ3A 4XBOA 3KNUA 1IPAA 4YQDA 3N4JA 3AXZA 4YVJA 3ILKA 3OIIA 1UAMA 4X3MA 4YQBA 4E8BA 4YVGA 1O6DA 1TO0A 1V6ZA 2EGVA 4YQLA 2QWVA 4YQCA 3OIJA 4X3LA 4L69A 4MCDA 2YY8A 2V3KA 3O7BA 1VHYA 4YQTA 1OY5A 4H3ZA 1MXIA 3GYQA 3N4KA 4YQIA 4YPWA 4YQ0A 4MCBA 4KGNA 3BBHA 1P9PA 1Z85A 2V3JA 5GMCA 4CNEA 3IC6A 2HA8A 5D9FA 3QUVA 3AI9X 4YQOA 1NS5A 4YQSA 4FAKA 4YVIA 3ONPA 1X7OA 2QMMA 4CNFA 1V2XA 4YQ9A 1J85A 3L8UA 4YVHA 1UAKA 4CNDA 4YQJA 1VHKA 3KY7A 4JALA 3OINA 4MCCA 1GZ0A 4YPZA 3AIAA 4PZKA 3E5YA 4YQ1A 2I6DA 1K3RA 3KTYA 4H3YA 3NK7A 2CX8A 1X7PA 4YVKA 2O3AA
chains in the Genus database with same CATH superfamily
3KW2A 4J3CA 1UALA 1ZJRA 4YQGA 2Z0YA 3IEFA 1UAJA 4YQ8A 4YQPA 4YQ5A 1NXZA 4YQ7A 4YQ6A 2EGWA 4CNGA 4KDZA 5GMBA 5CO4A 4YQKA 4IG6A 4YQAA 4JAKA 4YQNA 1VH0A 3DCMX 3BBDA 4YQQA 3BBEA 4YPYA 4YPXA 4YQ2A 4YQRA 3NK6A 5FAIA 5GM8A 4RG1A 4YQ4A 4YQ3A 4XBOA 3KNUA 1IPAA 4YQDA 3N4JA 3AXZA 4YVJA 3ILKA 3OIIA 1UAMA 4X3MA 4YQBA 4E8BA 4FMWA 4YVGA 1O6DA 1TO0A 1V6ZA 2EGVA 4YQLA 2QWVA 4YQCA 3OIJA 4X3LA 4L69A 4MCDA 2YY8A 2V3KA 3O7BA 1VHYA 4JWJA 4YQTA 1OY5A 4H3ZA 1MXIA 3GYQA 3N4KA 4YQIA 4YPWA 4YQ0A 4MCBA 4KGNA 3BBHA 1P9PA 1Z85A 2V3JA 4JWFA 5GMCA 4CNEA 3IC6A 2HA8A 5D9FA 3QUVA 3AI9X 4YQOA 1NS5A 4YQSA 4FAKA 4YVIA 3ONPA 1X7OA 2QMMA 4CNFA 1V2XA 4YQ9A 1J85A 3L8UA 4JWGA 1UAKA 4YVHA 4CNDA 4YQJA 1VHKA 3KY7A 4JALA 3OINA 4MCCA 1GZ0A 4JWHA 4YPZA 3AIAA 4PZKA 3E5YA 4YQ1A 2I6DA 1K3RA 3KTYA 4H3YA 3NK7A 2CX8A 1X7PA 4YVKA 2O3AA
chains in the Genus database with same CATH topology
3KW2A 4J3CA 1UALA 1ZJRA 4YQGA 2Z0YA 3IEFA 1UAJA 4YQ8A 4YQPA 4YQ5A 1NXZA 4YQ7A 4YQ6A 2EGWA 4CNGA 4KDZA 5GMBA 5CO4A 4YQKA 4IG6A 4YQAA 4JAKA 4YQNA 1VH0A 3DCMX 3BBDA 4YQQA 3BBEA 4YPYA 4YPXA 4YQ2A 4YQRA 3NK6A 5FAIA 5GM8A 4RG1A 4YQ4A 4YQ3A 4XBOA 3KNUA 1IPAA 4YQDA 3N4JA 3AXZA 4YVJA 3ILKA 3OIIA 1UAMA 4X3MA 4YQBA 4E8BA 4FMWA 4YVGA 1O6DA 1TO0A 1V6ZA 2EGVA 4YQLA 2QWVA 4YQCA 3OIJA 4X3LA 4L69A 4MCDA 2YY8A 2V3KA 3O7BA 1VHYA 4JWJA 4YQTA 1OY5A 4H3ZA 1MXIA 3GYQA 3N4KA 4YQIA 4YPWA 4YQ0A 4MCBA 4KGNA 3BBHA 1P9PA 1Z85A 2V3JA 4JWFA 5GMCA 4CNEA 3IC6A 2HA8A 5D9FA 3QUVA 3AI9X 4YQOA 1NS5A 4YQSA 4FAKA 4YVIA 3ONPA 1X7OA 2QMMA 4CNFA 1V2XA 4YQ9A 1J85A 3L8UA 4JWGA 1UAKA 4YVHA 4CNDA 4YQJA 1VHKA 3KY7A 4JALA 3OINA 4MCCA 1GZ0A 4JWHA 4YPZA 3AIAA 4PZKA 3E5YA 4YQ1A 2I6DA 1K3RA 3KTYA 4H3YA 3NK7A 2CX8A 1X7PA 4YVKA 2O3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KW2 A;  4J3C A;  1UAL A;  1ZJR A;  4YQG A;  2Z0Y A;  3IEF A;  1UAJ A;  4YQ8 A;  4YQP A;  4YQ5 A;  1NXZ A;  4YQ7 A;  4YQ6 A;  2EGW A;  4CNG A;  4KDZ A;  5GMB A;  5CO4 A;  4YQK A;  4IG6 A;  4YQA A;  4JAK A;  4YQN A;  1VH0 A;  3DCM X;  3BBD A;  4YQQ A;  3BBE A;  4YPY A;  4YPX A;  4YQ2 A;  4YQR A;  3NK6 A;  5FAI A;  5GM8 A;  4RG1 A;  4YQ4 A;  4YQ3 A;  4XBO A;  3KNU A;  1IPA A;  4YQD A;  3N4J A;  3AXZ A;  4YVJ A;  3ILK A;  3OII A;  1UAM A;  4X3M A;  4YQB A;  4E8B A;  4YVG A;  1O6D A;  1TO0 A;  1V6Z A;  2EGV A;  4YQL A;  2QWV A;  4YQC A;  3OIJ A;  4X3L A;  4L69 A;  4MCD A;  2YY8 A;  2V3K A;  3O7B A;  1VHY A;  4YQT A;  1OY5 A;  4H3Z A;  1MXI A;  3GYQ A;  3N4K A;  4YQI A;  4YPW A;  4YQ0 A;  4MCB A;  4KGN A;  3BBH A;  1P9P A;  1Z85 A;  2V3J A;  5GMC A;  4CNE A;  3IC6 A;  2HA8 A;  5D9F A;  3QUV A;  3AI9 X;  4YQO A;  1NS5 A;  4YQS A;  4FAK A;  4YVI A;  3ONP A;  1X7O A;  2QMM A;  4CNF A;  1V2X A;  4YQ9 A;  1J85 A;  3L8U A;  4YVH A;  1UAK A;  4CND A;  4YQJ A;  1VHK A;  3KY7 A;  4JAL A;  3OIN A;  4MCC A;  1GZ0 A;  4YPZ A;  3AIA A;  4PZK A;  3E5Y A;  4YQ1 A;  2I6D A;  1K3R A;  3KTY A;  4H3Y A;  3NK7 A;  2CX8 A;  1X7P A;  4YVK A;  2O3A A; 
#chains in the Genus database with same CATH topology
 3KW2 A;  4J3C A;  1UAL A;  1ZJR A;  4YQG A;  2Z0Y A;  3IEF A;  1UAJ A;  4YQ8 A;  4YQP A;  4YQ5 A;  1NXZ A;  4YQ7 A;  4YQ6 A;  2EGW A;  4CNG A;  4KDZ A;  5GMB A;  5CO4 A;  4YQK A;  4IG6 A;  4YQA A;  4JAK A;  4YQN A;  1VH0 A;  3DCM X;  3BBD A;  4YQQ A;  3BBE A;  4YPY A;  4YPX A;  4YQ2 A;  4YQR A;  3NK6 A;  5FAI A;  5GM8 A;  4RG1 A;  4YQ4 A;  4YQ3 A;  4XBO A;  3KNU A;  1IPA A;  4YQD A;  3N4J A;  3AXZ A;  4YVJ A;  3ILK A;  3OII A;  1UAM A;  4X3M A;  4YQB A;  4E8B A;  4FMW A;  4YVG A;  1O6D A;  1TO0 A;  1V6Z A;  2EGV A;  4YQL A;  2QWV A;  4YQC A;  3OIJ A;  4X3L A;  4L69 A;  4MCD A;  2YY8 A;  2V3K A;  3O7B A;  1VHY A;  4JWJ A;  4YQT A;  1OY5 A;  4H3Z A;  1MXI A;  3GYQ A;  3N4K A;  4YQI A;  4YPW A;  4YQ0 A;  4MCB A;  4KGN A;  3BBH A;  1P9P A;  1Z85 A;  2V3J A;  4JWF A;  5GMC A;  4CNE A;  3IC6 A;  2HA8 A;  5D9F A;  3QUV A;  3AI9 X;  4YQO A;  1NS5 A;  4YQS A;  4FAK A;  4YVI A;  3ONP A;  1X7O A;  2QMM A;  4CNF A;  1V2X A;  4YQ9 A;  1J85 A;  3L8U A;  4JWG A;  1UAK A;  4YVH A;  4CND A;  4YQJ A;  1VHK A;  3KY7 A;  4JAL A;  3OIN A;  4MCC A;  1GZ0 A;  4JWH A;  4YPZ A;  3AIA A;  4PZK A;  3E5Y A;  4YQ1 A;  2I6D A;  1K3R A;  3KTY A;  4H3Y A;  3NK7 A;  2CX8 A;  1X7P A;  4YVK A;  2O3A A; 
#chains in the Genus database with same CATH homology
 3KW2 A;  4J3C A;  1UAL A;  1ZJR A;  4YQG A;  2Z0Y A;  3IEF A;  1UAJ A;  4YQ8 A;  4YQP A;  4YQ5 A;  1NXZ A;  4YQ7 A;  4YQ6 A;  2EGW A;  4CNG A;  4KDZ A;  5GMB A;  5CO4 A;  4YQK A;  4IG6 A;  4YQA A;  4JAK A;  4YQN A;  1VH0 A;  3DCM X;  3BBD A;  4YQQ A;  3BBE A;  4YPY A;  4YPX A;  4YQ2 A;  4YQR A;  3NK6 A;  5FAI A;  5GM8 A;  4RG1 A;  4YQ4 A;  4YQ3 A;  4XBO A;  3KNU A;  1IPA A;  4YQD A;  3N4J A;  3AXZ A;  4YVJ A;  3ILK A;  3OII A;  1UAM A;  4X3M A;  4YQB A;  4E8B A;  4FMW A;  4YVG A;  1O6D A;  1TO0 A;  1V6Z A;  2EGV A;  4YQL A;  2QWV A;  4YQC A;  3OIJ A;  4X3L A;  4L69 A;  4MCD A;  2YY8 A;  2V3K A;  3O7B A;  1VHY A;  4JWJ A;  4YQT A;  1OY5 A;  4H3Z A;  1MXI A;  3GYQ A;  3N4K A;  4YQI A;  4YPW A;  4YQ0 A;  4MCB A;  4KGN A;  3BBH A;  1P9P A;  1Z85 A;  2V3J A;  4JWF A;  5GMC A;  4CNE A;  3IC6 A;  2HA8 A;  5D9F A;  3QUV A;  3AI9 X;  4YQO A;  1NS5 A;  4YQS A;  4FAK A;  4YVI A;  3ONP A;  1X7O A;  2QMM A;  4CNF A;  1V2X A;  4YQ9 A;  1J85 A;  3L8U A;  4JWG A;  1UAK A;  4YVH A;  4CND A;  4YQJ A;  1VHK A;  3KY7 A;  4JAL A;  3OIN A;  4MCC A;  1GZ0 A;  4JWH A;  4YPZ A;  3AIA A;  4PZK A;  3E5Y A;  4YQ1 A;  2I6D A;  1K3R A;  3KTY A;  4H3Y A;  3NK7 A;  2CX8 A;  1X7P A;  4YVK A;  2O3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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