3BBHA

M. jannaschii nep1 complexed with sinefungin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
204
structure length
204
Chain Sequence
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Ribosome biogenesis protein NEP1-like
total genus 69
structure length 204
sequence length 204
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3bbhA00
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4MCBA 4YQJA 4JALA 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4XBOA 1VHKA 4YPWA 4YQLA 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 3OIIA 4MCCA 3KW2A 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 3IEFA 5GMCA 4IG6A 1MXIA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 2V3JA 4YQ9A 4X3LA 1V2XA 4H3YA 3ILKA 4YQOA 4YQBA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1NS5A 3AXZA 2HA8A 4YQ3A 1NXZA 4FAKA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 1V6ZA 3L8UA 4YQPA 1TO0A 3BBEA 3DCMX 4YQ0A 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH superfamily
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4JWJA 4MCBA 4YQJA 4JALA 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4XBOA 1VHKA 4YPWA 4YQLA 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 3OIIA 4MCCA 3KW2A 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 3IEFA 5GMCA 4IG6A 1MXIA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 2V3JA 4YQ9A 4X3LA 1V2XA 4H3YA 3ILKA 4YQOA 4YQBA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1NS5A 4JWFA 3AXZA 2HA8A 4JWGA 4YQ3A 1NXZA 4FAKA 4FMWA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 1V6ZA 3L8UA 4YQPA 1TO0A 3BBEA 3DCMX 4YQ0A 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4JWHA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH topology
1O6DA 4YQ8A 4YVKA 4YPXA 3AI9X 3OIJA 4YPZA 3KY7A 4JWJA 4MCBA 4YQJA 4JALA 4RG1A 4YQ4A 1P9PA 2EGWA 4YQGA 4YQSA 4JAKA 2O3AA 2QWVA 1X7OA 3IC6A 4YQTA 4YQNA 3ONPA 5CO4A 4CNGA 5D9FA 4XBOA 1VHKA 4YPWA 4YQLA 4J3CA 4L69A 2I6DA 4YVIA 4YQ5A 3E5YA 3NK7A 1OY5A 4KDZA 2YY8A 2QMMA 4YQDA 3BBDA 4YQRA 3KTYA 2V3KA 4YQ2A 4YQ1A 3OIIA 4MCCA 3KW2A 1UAKA 3O7BA 1Z85A 1J85A 4CNDA 1K3RA 3IEFA 5GMCA 4IG6A 1MXIA 4YQIA 4KGNA 1ZJRA 4YVHA 4YQKA 2Z0YA 1X7PA 3QUVA 2V3JA 4YQ9A 4X3LA 1V2XA 4H3YA 3ILKA 4YQOA 4YQBA 3AIAA 4CNEA 1UAMA 3NK6A 4YQCA 2EGVA 5GM8A 2CX8A 4MCDA 4X3MA 4YQQA 1NS5A 4JWFA 3AXZA 2HA8A 4JWGA 4YQ3A 1NXZA 4FAKA 4FMWA 4YVGA 3N4JA 1IPAA 3BBHA 1UAJA 1V6ZA 3L8UA 4YQPA 1TO0A 3BBEA 3DCMX 4YQ0A 4YQ6A 1GZ0A 4H3ZA 3KNUA 4YPYA 4E8BA 1VHYA 1VH0A 4YVJA 4JWHA 4CNFA 5FAIA 4YQ7A 4PZKA 5GMBA 1UALA 3N4KA 3OINA 3GYQA 4YQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4MCB A;  4YQJ A;  4JAL A;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4XBO A;  1VHK A;  4YPW A;  4YQL A;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  3OII A;  4MCC A;  3KW2 A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  2V3J A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3ILK A;  4YQO A;  4YQB A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1NS5 A;  3AXZ A;  2HA8 A;  4YQ3 A;  1NXZ A;  4FAK A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  1V6Z A;  3L8U A;  4YQP A;  1TO0 A;  3BBE A;  3DCM X;  4YQ0 A;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
#chains in the Genus database with same CATH topology
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4JWJ A;  4MCB A;  4YQJ A;  4JAL A;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4XBO A;  1VHK A;  4YPW A;  4YQL A;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  3OII A;  4MCC A;  3KW2 A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  2V3J A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3ILK A;  4YQO A;  4YQB A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1NS5 A;  4JWF A;  3AXZ A;  2HA8 A;  4JWG A;  4YQ3 A;  1NXZ A;  4FAK A;  4FMW A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  1V6Z A;  3L8U A;  4YQP A;  1TO0 A;  3BBE A;  3DCM X;  4YQ0 A;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4JWH A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
#chains in the Genus database with same CATH homology
 1O6D A;  4YQ8 A;  4YVK A;  4YPX A;  3AI9 X;  3OIJ A;  4YPZ A;  3KY7 A;  4JWJ A;  4MCB A;  4YQJ A;  4JAL A;  4RG1 A;  4YQ4 A;  1P9P A;  2EGW A;  4YQG A;  4YQS A;  4JAK A;  2O3A A;  2QWV A;  1X7O A;  3IC6 A;  4YQT A;  4YQN A;  3ONP A;  5CO4 A;  4CNG A;  5D9F A;  4XBO A;  1VHK A;  4YPW A;  4YQL A;  4J3C A;  4L69 A;  2I6D A;  4YVI A;  4YQ5 A;  3E5Y A;  3NK7 A;  1OY5 A;  4KDZ A;  2YY8 A;  2QMM A;  4YQD A;  3BBD A;  4YQR A;  3KTY A;  2V3K A;  4YQ2 A;  4YQ1 A;  3OII A;  4MCC A;  3KW2 A;  1UAK A;  3O7B A;  1Z85 A;  1J85 A;  4CND A;  1K3R A;  3IEF A;  5GMC A;  4IG6 A;  1MXI A;  4YQI A;  4KGN A;  1ZJR A;  4YVH A;  4YQK A;  2Z0Y A;  1X7P A;  3QUV A;  2V3J A;  4YQ9 A;  4X3L A;  1V2X A;  4H3Y A;  3ILK A;  4YQO A;  4YQB A;  3AIA A;  4CNE A;  1UAM A;  3NK6 A;  4YQC A;  2EGV A;  5GM8 A;  2CX8 A;  4MCD A;  4X3M A;  4YQQ A;  1NS5 A;  4JWF A;  3AXZ A;  2HA8 A;  4JWG A;  4YQ3 A;  1NXZ A;  4FAK A;  4FMW A;  4YVG A;  3N4J A;  1IPA A;  3BBH A;  1UAJ A;  1V6Z A;  3L8U A;  4YQP A;  1TO0 A;  3BBE A;  3DCM X;  4YQ0 A;  4YQ6 A;  1GZ0 A;  4H3Z A;  3KNU A;  4YPY A;  4E8B A;  1VHY A;  1VH0 A;  4YVJ A;  4JWH A;  4CNF A;  5FAI A;  4YQ7 A;  4PZK A;  5GMB A;  1UAL A;  3N4K A;  3OIN A;  3GYQ A;  4YQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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