3BBHA

M. jannaschii nep1 complexed with sinefungin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
204
structure length
204
Chain Sequence
TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Ribosome biogenesis protein NEP1-like
total genus 69
structure length 204
sequence length 204
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3bbhA00
3BBDA 4YQ4A 3OIIA 4YPXA 2EGVA 1VHYA 1GZ0A 3IEFA 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 2I6DA 4YQ0A 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 1V2XA 4CNDA 4YVKA 3KY7A 4YQBA 1NXZA 1UAMA 4YQDA 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 3KNUA 5CO4A 4CNFA 4KDZA 2QWVA 4YQPA 1UAKA 4YPZA 4YQAA 4L69A 4YPYA 4YQ9A 4YVHA 3L8UA 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 2QMMA 4YQJA 3NK7A 4X3MA 4YVJA 2O3AA 4H3YA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 2CX8A 3OINA 4YQOA 4YQ6A 4YVIA 1MXIA 1J85A 3IC6A 3O7BA 1P9PA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 1X7PA 4YQ8A 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH superfamily
3BBDA 4YQ4A 3OIIA 4YPXA 2EGVA 4JWGA 1VHYA 1GZ0A 3IEFA 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 2I6DA 4YQ0A 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 1V2XA 4CNDA 4YVKA 3KY7A 4YQBA 1NXZA 1UAMA 4YQDA 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 3KNUA 5CO4A 4CNFA 4KDZA 2QWVA 4YQPA 1UAKA 4YPZA 4YQAA 4JWHA 4L69A 4YPYA 4YQ9A 4YVHA 3L8UA 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 2QMMA 4YQJA 3NK7A 4X3MA 4YVJA 2O3AA 4H3YA 4FMWA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 2CX8A 3OINA 4YQOA 4YQ6A 4YVIA 1MXIA 1J85A 3IC6A 3O7BA 4JWJA 1P9PA 4JWFA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 1X7PA 4YQ8A 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH topology
3BBDA 4YQ4A 3OIIA 4YPXA 2EGVA 4JWGA 1VHYA 1GZ0A 3IEFA 1TO0A 3BBEA 3KW2A 4CNEA 4YQ2A 1VHKA 1V6ZA 1ZJRA 2YY8A 4MCBA 4E8BA 4KGNA 3N4KA 3BBHA 4YQKA 4YQQA 3N4JA 1VH0A 2V3KA 4J3CA 2EGWA 4XBOA 3AXZA 3ILKA 2I6DA 4YQ0A 2Z0YA 4YPWA 1K3RA 4YQGA 4YQTA 1X7OA 2HA8A 4RG1A 4MCCA 4YQCA 4YQIA 4JALA 1V2XA 4CNDA 4YVKA 3KY7A 4YQBA 1NXZA 1UAMA 4YQDA 3DCMX 1OY5A 3KTYA 5GMCA 5GM8A 4YVGA 4YQNA 3KNUA 5CO4A 4CNFA 4KDZA 2QWVA 4YQPA 1UAKA 4YPZA 4YQAA 4JWHA 4L69A 4YPYA 4YQ9A 4YVHA 3L8UA 3AIAA 4CNGA 4YQ3A 3OIJA 4H3ZA 1IPAA 2QMMA 4YQJA 3NK7A 4X3MA 4YVJA 2O3AA 4H3YA 4FMWA 3E5YA 3ONPA 4MCDA 3NK6A 4YQ5A 2V3JA 4IG6A 4X3LA 1Z85A 4YQ1A 4YQRA 4YQ7A 1O6DA 4YQLA 2CX8A 3OINA 4YQOA 4YQ6A 4YVIA 1MXIA 1J85A 3IC6A 3O7BA 4JWJA 1P9PA 4JWFA 3AI9X 4JAKA 3GYQA 5GMBA 4FAKA 1X7PA 4YQ8A 4YQSA 5FAIA 3QUVA 1UALA 5D9FA 4PZKA 1NS5A 1UAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BBD A;  4YQ4 A;  3OII A;  4YPX A;  2EGV A;  1VHY A;  1GZ0 A;  3IEF A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  2I6D A;  4YQ0 A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  1V2X A;  4CND A;  4YVK A;  3KY7 A;  4YQB A;  1NXZ A;  1UAM A;  4YQD A;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  2QWV A;  4YQP A;  1UAK A;  4YPZ A;  4YQA A;  4L69 A;  4YPY A;  4YQ9 A;  4YVH A;  3L8U A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  2QMM A;  4YQJ A;  3NK7 A;  4X3M A;  4YVJ A;  2O3A A;  4H3Y A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  2CX8 A;  3OIN A;  4YQO A;  4YQ6 A;  4YVI A;  1MXI A;  1J85 A;  3IC6 A;  3O7B A;  1P9P A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  1X7P A;  4YQ8 A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  4PZK A;  1NS5 A;  1UAJ A; 
#chains in the Genus database with same CATH topology
 3BBD A;  4YQ4 A;  3OII A;  4YPX A;  2EGV A;  4JWG A;  1VHY A;  1GZ0 A;  3IEF A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  2I6D A;  4YQ0 A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  1V2X A;  4CND A;  4YVK A;  3KY7 A;  4YQB A;  1NXZ A;  1UAM A;  4YQD A;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  2QWV A;  4YQP A;  1UAK A;  4YPZ A;  4YQA A;  4JWH A;  4L69 A;  4YPY A;  4YQ9 A;  4YVH A;  3L8U A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  2QMM A;  4YQJ A;  3NK7 A;  4X3M A;  4YVJ A;  2O3A A;  4H3Y A;  4FMW A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  2CX8 A;  3OIN A;  4YQO A;  4YQ6 A;  4YVI A;  1MXI A;  1J85 A;  3IC6 A;  3O7B A;  4JWJ A;  1P9P A;  4JWF A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  1X7P A;  4YQ8 A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  4PZK A;  1NS5 A;  1UAJ A; 
#chains in the Genus database with same CATH homology
 3BBD A;  4YQ4 A;  3OII A;  4YPX A;  2EGV A;  4JWG A;  1VHY A;  1GZ0 A;  3IEF A;  1TO0 A;  3BBE A;  3KW2 A;  4CNE A;  4YQ2 A;  1VHK A;  1V6Z A;  1ZJR A;  2YY8 A;  4MCB A;  4E8B A;  4KGN A;  3N4K A;  3BBH A;  4YQK A;  4YQQ A;  3N4J A;  1VH0 A;  2V3K A;  4J3C A;  2EGW A;  4XBO A;  3AXZ A;  3ILK A;  2I6D A;  4YQ0 A;  2Z0Y A;  4YPW A;  1K3R A;  4YQG A;  4YQT A;  1X7O A;  2HA8 A;  4RG1 A;  4MCC A;  4YQC A;  4YQI A;  4JAL A;  1V2X A;  4CND A;  4YVK A;  3KY7 A;  4YQB A;  1NXZ A;  1UAM A;  4YQD A;  3DCM X;  1OY5 A;  3KTY A;  5GMC A;  5GM8 A;  4YVG A;  4YQN A;  3KNU A;  5CO4 A;  4CNF A;  4KDZ A;  2QWV A;  4YQP A;  1UAK A;  4YPZ A;  4YQA A;  4JWH A;  4L69 A;  4YPY A;  4YQ9 A;  4YVH A;  3L8U A;  3AIA A;  4CNG A;  4YQ3 A;  3OIJ A;  4H3Z A;  1IPA A;  2QMM A;  4YQJ A;  3NK7 A;  4X3M A;  4YVJ A;  2O3A A;  4H3Y A;  4FMW A;  3E5Y A;  3ONP A;  4MCD A;  3NK6 A;  4YQ5 A;  2V3J A;  4IG6 A;  4X3L A;  1Z85 A;  4YQ1 A;  4YQR A;  4YQ7 A;  1O6D A;  4YQL A;  2CX8 A;  3OIN A;  4YQO A;  4YQ6 A;  4YVI A;  1MXI A;  1J85 A;  3IC6 A;  3O7B A;  4JWJ A;  1P9P A;  4JWF A;  3AI9 X;  4JAK A;  3GYQ A;  5GMB A;  4FAK A;  1X7P A;  4YQ8 A;  4YQS A;  5FAI A;  3QUV A;  1UAL A;  5D9F A;  4PZK A;  1NS5 A;  1UAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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