3O7BA

Crystal structure of archaeoglobus fulgidus nep1 bound to s-adenosylhomocysteine
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
Knots found
sequence length
216
structure length
216
Chain Sequence
MGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAMKSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRLPRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREKGGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSLYVTSRVLCEYERVRAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Transferase
source organism Archaeoglobus fulgidus
molecule keywords Ribosome biogenesis Nep1 RNA methyltransferase
total genus 75
structure length 216
sequence length 216
other databases KnotProt 2.0: K +31
ec nomenclature
pdb deposition date 2010-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3o7bA00
4YQIA 4YQTA 4YQ0A 4YQGA 1UAKA 1NXZA 3KW2A 4E8BA 1UAMA 1ZJRA 4YPZA 4YQ8A 4YQDA 4YQ5A 2EGWA 4MCDA 4JALA 4CNFA 5GM8A 1V2XA 4J3CA 2I6DA 4CNDA 4YPWA 2CX8A 2QMMA 3IC6A 3OIJA 4YQNA 4RG1A 1V6ZA 3NK7A 4YQJA 4MCCA 3N4JA 1UALA 1O6DA 4YQ9A 3IEFA 4YQ7A 4FAKA 4YQCA 1X7OA 3QUVA 1VH0A 1TO0A 2YY8A 3DCMX 3E5YA 1IPAA 1K3RA 5D9FA 3L8UA 4YQ3A 2O3AA 4YPYA 5GMBA 5FAIA 4YQ1A 3KTYA 3BBDA 3BBEA 4YQ2A 4YVJA 3KY7A 4KDZA 4YQLA 4YQBA 4YQSA 1P9PA 4H3YA 2HA8A 3OINA 3ILKA 3N4KA 4YQ6A 3GYQA 4YVIA 4YQPA 5CO4A 3NK6A 4XBOA 4YVHA 4YQQA 3OIIA 3ONPA 1GZ0A 4CNGA 3KNUA 4KGNA 4YQOA 1OY5A 4X3LA 4YVGA 1NS5A 4YVKA 3AXZA 3AIAA 1MXIA 4YQAA 2Z0YA 4CNEA 3O7BA 1VHKA 4YQKA 4YQRA 2V3KA 4YQ4A 4MCBA 3BBHA 1X7PA 4JAKA 4L69A 1Z85A 2QWVA 3AI9X 4IG6A 4X3MA 2EGVA 4YPXA 4PZKA 4H3ZA 1UAJA 5GMCA 1VHYA 2V3JA 1J85A
chains in the Genus database with same CATH superfamily
4YQIA 4YQTA 4YQ0A 4YQGA 1UAKA 1NXZA 3KW2A 4E8BA 1UAMA 1ZJRA 4YPZA 4YQ8A 4YQDA 4YQ5A 2EGWA 4MCDA 4JALA 4CNFA 5GM8A 1V2XA 4J3CA 2I6DA 4CNDA 4YPWA 2CX8A 2QMMA 3IC6A 3OIJA 4YQNA 4RG1A 1V6ZA 3NK7A 4YQJA 4MCCA 3N4JA 1UALA 1O6DA 4YQ9A 3IEFA 4YQ7A 4FAKA 4YQCA 1X7OA 3QUVA 1VH0A 1TO0A 2YY8A 3DCMX 3E5YA 1IPAA 1K3RA 5D9FA 3L8UA 4YQ3A 2O3AA 4YPYA 5GMBA 5FAIA 4YQ1A 3KTYA 3BBDA 3BBEA 4YQ2A 4YVJA 3KY7A 4KDZA 4YQLA 4YQBA 4YQSA 1P9PA 4H3YA 2HA8A 3OINA 3ILKA 3N4KA 4YQ6A 3GYQA 4YVIA 4JWGA 4YQPA 5CO4A 3NK6A 4XBOA 4YVHA 4YQQA 3OIIA 3ONPA 1GZ0A 4CNGA 3KNUA 4KGNA 4YQOA 1OY5A 4X3LA 4YVGA 4JWJA 1NS5A 4YVKA 3AXZA 3AIAA 1MXIA 4YQAA 2Z0YA 4CNEA 3O7BA 1VHKA 4YQKA 4YQRA 2V3KA 4YQ4A 4MCBA 3BBHA 1X7PA 4JAKA 4L69A 1Z85A 2QWVA 3AI9X 4IG6A 4X3MA 4FMWA 2EGVA 4YPXA 4PZKA 4H3ZA 1UAJA 4JWHA 5GMCA 1VHYA 4JWFA 2V3JA 1J85A
chains in the Genus database with same CATH topology
4YQIA 4YQTA 4YQ0A 4YQGA 1UAKA 1NXZA 3KW2A 4E8BA 1UAMA 1ZJRA 4YPZA 4YQ8A 4YQDA 4YQ5A 2EGWA 4MCDA 4JALA 4CNFA 5GM8A 1V2XA 4J3CA 2I6DA 4CNDA 4YPWA 2CX8A 2QMMA 3IC6A 3OIJA 4YQNA 4RG1A 1V6ZA 3NK7A 4YQJA 4MCCA 3N4JA 1UALA 1O6DA 4YQ9A 3IEFA 4YQ7A 4FAKA 4YQCA 1X7OA 3QUVA 1VH0A 1TO0A 2YY8A 3DCMX 3E5YA 1IPAA 1K3RA 5D9FA 3L8UA 4YQ3A 2O3AA 4YPYA 5GMBA 5FAIA 4YQ1A 3KTYA 3BBDA 3BBEA 4YQ2A 4YVJA 3KY7A 4KDZA 4YQLA 4YQBA 4YQSA 1P9PA 4H3YA 2HA8A 3OINA 3ILKA 3N4KA 4YQ6A 3GYQA 4YVIA 4JWGA 4YQPA 5CO4A 3NK6A 4XBOA 4YVHA 4YQQA 3OIIA 3ONPA 1GZ0A 4CNGA 3KNUA 4KGNA 4YQOA 1OY5A 4X3LA 4YVGA 4JWJA 1NS5A 4YVKA 3AXZA 3AIAA 1MXIA 4YQAA 2Z0YA 4CNEA 3O7BA 1VHKA 4YQKA 4YQRA 2V3KA 4YQ4A 4MCBA 3BBHA 1X7PA 4JAKA 4L69A 1Z85A 2QWVA 3AI9X 4IG6A 4X3MA 4FMWA 2EGVA 4YPXA 4PZKA 4H3ZA 1UAJA 4JWHA 5GMCA 1VHYA 4JWFA 2V3JA 1J85A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQI A;  4YQT A;  4YQ0 A;  4YQG A;  1UAK A;  1NXZ A;  3KW2 A;  4E8B A;  1UAM A;  1ZJR A;  4YPZ A;  4YQ8 A;  4YQD A;  4YQ5 A;  2EGW A;  4MCD A;  4JAL A;  4CNF A;  5GM8 A;  1V2X A;  4J3C A;  2I6D A;  4CND A;  4YPW A;  2CX8 A;  2QMM A;  3IC6 A;  3OIJ A;  4YQN A;  4RG1 A;  1V6Z A;  3NK7 A;  4YQJ A;  4MCC A;  3N4J A;  1UAL A;  1O6D A;  4YQ9 A;  3IEF A;  4YQ7 A;  4FAK A;  4YQC A;  1X7O A;  3QUV A;  1VH0 A;  1TO0 A;  2YY8 A;  3DCM X;  3E5Y A;  1IPA A;  1K3R A;  5D9F A;  3L8U A;  4YQ3 A;  2O3A A;  4YPY A;  5GMB A;  5FAI A;  4YQ1 A;  3KTY A;  3BBD A;  3BBE A;  4YQ2 A;  4YVJ A;  3KY7 A;  4KDZ A;  4YQL A;  4YQB A;  4YQS A;  1P9P A;  4H3Y A;  2HA8 A;  3OIN A;  3ILK A;  3N4K A;  4YQ6 A;  3GYQ A;  4YVI A;  4YQP A;  5CO4 A;  3NK6 A;  4XBO A;  4YVH A;  4YQQ A;  3OII A;  3ONP A;  1GZ0 A;  4CNG A;  3KNU A;  4KGN A;  4YQO A;  1OY5 A;  4X3L A;  4YVG A;  1NS5 A;  4YVK A;  3AXZ A;  3AIA A;  1MXI A;  4YQA A;  2Z0Y A;  4CNE A;  3O7B A;  1VHK A;  4YQK A;  4YQR A;  2V3K A;  4YQ4 A;  4MCB A;  3BBH A;  1X7P A;  4JAK A;  4L69 A;  1Z85 A;  2QWV A;  3AI9 X;  4IG6 A;  4X3M A;  2EGV A;  4YPX A;  4PZK A;  4H3Z A;  1UAJ A;  5GMC A;  1VHY A;  2V3J A;  1J85 A; 
#chains in the Genus database with same CATH topology
 4YQI A;  4YQT A;  4YQ0 A;  4YQG A;  1UAK A;  1NXZ A;  3KW2 A;  4E8B A;  1UAM A;  1ZJR A;  4YPZ A;  4YQ8 A;  4YQD A;  4YQ5 A;  2EGW A;  4MCD A;  4JAL A;  4CNF A;  5GM8 A;  1V2X A;  4J3C A;  2I6D A;  4CND A;  4YPW A;  2CX8 A;  2QMM A;  3IC6 A;  3OIJ A;  4YQN A;  4RG1 A;  1V6Z A;  3NK7 A;  4YQJ A;  4MCC A;  3N4J A;  1UAL A;  1O6D A;  4YQ9 A;  3IEF A;  4YQ7 A;  4FAK A;  4YQC A;  1X7O A;  3QUV A;  1VH0 A;  1TO0 A;  2YY8 A;  3DCM X;  3E5Y A;  1IPA A;  1K3R A;  5D9F A;  3L8U A;  4YQ3 A;  2O3A A;  4YPY A;  5GMB A;  5FAI A;  4YQ1 A;  3KTY A;  3BBD A;  3BBE A;  4YQ2 A;  4YVJ A;  3KY7 A;  4KDZ A;  4YQL A;  4YQB A;  4YQS A;  1P9P A;  4H3Y A;  2HA8 A;  3OIN A;  3ILK A;  3N4K A;  4YQ6 A;  3GYQ A;  4YVI A;  4JWG A;  4YQP A;  5CO4 A;  3NK6 A;  4XBO A;  4YVH A;  4YQQ A;  3OII A;  3ONP A;  1GZ0 A;  4CNG A;  3KNU A;  4KGN A;  4YQO A;  1OY5 A;  4X3L A;  4YVG A;  4JWJ A;  1NS5 A;  4YVK A;  3AXZ A;  3AIA A;  1MXI A;  4YQA A;  2Z0Y A;  4CNE A;  3O7B A;  1VHK A;  4YQK A;  4YQR A;  2V3K A;  4YQ4 A;  4MCB A;  3BBH A;  1X7P A;  4JAK A;  4L69 A;  1Z85 A;  2QWV A;  3AI9 X;  4IG6 A;  4X3M A;  4FMW A;  2EGV A;  4YPX A;  4PZK A;  4H3Z A;  1UAJ A;  4JWH A;  5GMC A;  1VHY A;  4JWF A;  2V3J A;  1J85 A; 
#chains in the Genus database with same CATH homology
 4YQI A;  4YQT A;  4YQ0 A;  4YQG A;  1UAK A;  1NXZ A;  3KW2 A;  4E8B A;  1UAM A;  1ZJR A;  4YPZ A;  4YQ8 A;  4YQD A;  4YQ5 A;  2EGW A;  4MCD A;  4JAL A;  4CNF A;  5GM8 A;  1V2X A;  4J3C A;  2I6D A;  4CND A;  4YPW A;  2CX8 A;  2QMM A;  3IC6 A;  3OIJ A;  4YQN A;  4RG1 A;  1V6Z A;  3NK7 A;  4YQJ A;  4MCC A;  3N4J A;  1UAL A;  1O6D A;  4YQ9 A;  3IEF A;  4YQ7 A;  4FAK A;  4YQC A;  1X7O A;  3QUV A;  1VH0 A;  1TO0 A;  2YY8 A;  3DCM X;  3E5Y A;  1IPA A;  1K3R A;  5D9F A;  3L8U A;  4YQ3 A;  2O3A A;  4YPY A;  5GMB A;  5FAI A;  4YQ1 A;  3KTY A;  3BBD A;  3BBE A;  4YQ2 A;  4YVJ A;  3KY7 A;  4KDZ A;  4YQL A;  4YQB A;  4YQS A;  1P9P A;  4H3Y A;  2HA8 A;  3OIN A;  3ILK A;  3N4K A;  4YQ6 A;  3GYQ A;  4YVI A;  4JWG A;  4YQP A;  5CO4 A;  3NK6 A;  4XBO A;  4YVH A;  4YQQ A;  3OII A;  3ONP A;  1GZ0 A;  4CNG A;  3KNU A;  4KGN A;  4YQO A;  1OY5 A;  4X3L A;  4YVG A;  4JWJ A;  1NS5 A;  4YVK A;  3AXZ A;  3AIA A;  1MXI A;  4YQA A;  2Z0Y A;  4CNE A;  3O7B A;  1VHK A;  4YQK A;  4YQR A;  2V3K A;  4YQ4 A;  4MCB A;  3BBH A;  1X7P A;  4JAK A;  4L69 A;  1Z85 A;  2QWV A;  3AI9 X;  4IG6 A;  4X3M A;  4FMW A;  2EGV A;  4YPX A;  4PZK A;  4H3Z A;  1UAJ A;  4JWH A;  5GMC A;  1VHY A;  4JWF A;  2V3J A;  1J85 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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