3OIIA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
Knots found
sequence length
225
structure length
216
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 67
structure length 216
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oiiA01
4YQNA 1P9PA 3ONPA 4CNDA 5GM8A 4YQ1A 4YQBA 4FAKA 3AI9X 4L69A 4CNEA 4YQ3A 4YQKA 4JAKA 4YQ7A 4YQCA 4YPXA 3N4KA 4YPZA 4YQAA 1J85A 4YQ8A 4PZKA 5CO4A 4YQ6A 3BBEA 4J3CA 3O7BA 4YQSA 3GYQA 3ILKA 4X3MA 1UALA 4YVGA 4YQPA 4YQ9A 1MXIA 3N4JA 1X7OA 4YPWA 1GZ0A 1Z85A 3DCMX 4YQLA 1UAKA 5D9FA 4E8BA 2Z0YA 3NK6A 3QUVA 4YVJA 4JALA 2QWVA 1OY5A 1UAMA 4XBOA 4YQIA 1NXZA 4MCDA 2EGVA 1O6DA 3KTYA 4CNFA 3NK7A 4YQQA 1ZJRA 3OIIA 2O3AA 3BBDA 1V6ZA 1VHKA 3L8UA 5GMCA 4X3LA 4IG6A 4MCCA 1TO0A 4YQ4A 2I6DA 4YQGA 4KDZA 2V3JA 4YQOA 4YVKA 1NS5A 4YQDA 3AXZA 4YQTA 4H3ZA 1V2XA 3AIAA 4YPYA 4CNGA 2EGWA 3OINA 4KGNA 4RG1A 4MCBA 3OIJA 3E5YA 2QMMA 1VH0A 4YQ0A 3KW2A 1VHYA 4YVIA 2YY8A 4H3YA 4YQ5A 1X7PA 4YQJA 5FAIA 5GMBA 1UAJA 2CX8A 4YQ2A 4YVHA 3BBHA 2HA8A 3IEFA 4YQRA 3KY7A 1K3RA 1IPAA 3IC6A 3KNUA 2V3KA
chains in the Genus database with same CATH superfamily
4YQNA 1P9PA 3ONPA 4CNDA 5GM8A 4YQ1A 4YQBA 4FAKA 3AI9X 4L69A 4CNEA 4YQ3A 4YQKA 4JAKA 4YQ7A 4YQCA 4YPXA 3N4KA 4YPZA 4YQAA 1J85A 4YQ8A 4PZKA 5CO4A 4YQ6A 3BBEA 4J3CA 3O7BA 4YQSA 3GYQA 3ILKA 4X3MA 1UALA 4YVGA 4YQPA 4JWGA 4YQ9A 4JWHA 1MXIA 3N4JA 1X7OA 4YPWA 1GZ0A 1Z85A 3DCMX 4YQLA 1UAKA 5D9FA 4E8BA 2Z0YA 3NK6A 3QUVA 4YVJA 4JALA 2QWVA 1OY5A 4JWJA 1UAMA 4XBOA 4YQIA 1NXZA 4MCDA 2EGVA 4FMWA 1O6DA 3KTYA 4JWFA 4CNFA 3NK7A 4YQQA 1ZJRA 3OIIA 2O3AA 3BBDA 1V6ZA 1VHKA 3L8UA 5GMCA 4X3LA 4IG6A 4MCCA 1TO0A 4YQ4A 2I6DA 4YQGA 4KDZA 2V3JA 4YQOA 4YVKA 1NS5A 4YQDA 3AXZA 4YQTA 4H3ZA 1V2XA 3AIAA 4YPYA 4CNGA 2EGWA 3OINA 4KGNA 4RG1A 4MCBA 3OIJA 3E5YA 2QMMA 1VH0A 4YQ0A 3KW2A 1VHYA 4YVIA 2YY8A 4H3YA 4YQ5A 1X7PA 4YQJA 5FAIA 5GMBA 1UAJA 2CX8A 4YQ2A 4YVHA 3BBHA 2HA8A 3IEFA 4YQRA 3KY7A 1K3RA 1IPAA 3IC6A 3KNUA 2V3KA
chains in the Genus database with same CATH topology
4YQNA 1P9PA 3ONPA 4CNDA 5GM8A 4YQ1A 4YQBA 4FAKA 3AI9X 4L69A 4CNEA 4YQ3A 4YQKA 4JAKA 4YQ7A 4YQCA 4YPXA 3N4KA 4YPZA 4YQAA 1J85A 4YQ8A 4PZKA 5CO4A 4YQ6A 3BBEA 4J3CA 3O7BA 4YQSA 3GYQA 3ILKA 4X3MA 1UALA 4YVGA 4YQPA 4JWGA 4YQ9A 4JWHA 1MXIA 3N4JA 1X7OA 4YPWA 1GZ0A 1Z85A 3DCMX 4YQLA 1UAKA 5D9FA 4E8BA 2Z0YA 3NK6A 3QUVA 4YVJA 4JALA 2QWVA 1OY5A 4JWJA 1UAMA 4XBOA 4YQIA 1NXZA 4MCDA 2EGVA 4FMWA 1O6DA 3KTYA 4JWFA 4CNFA 3NK7A 4YQQA 1ZJRA 3OIIA 2O3AA 3BBDA 1V6ZA 1VHKA 3L8UA 5GMCA 4X3LA 4IG6A 4MCCA 1TO0A 4YQ4A 2I6DA 4YQGA 4KDZA 2V3JA 4YQOA 4YVKA 1NS5A 4YQDA 3AXZA 4YQTA 4H3ZA 1V2XA 3AIAA 4YPYA 4CNGA 2EGWA 3OINA 4KGNA 4RG1A 4MCBA 3OIJA 3E5YA 2QMMA 1VH0A 4YQ0A 3KW2A 1VHYA 4YVIA 2YY8A 4H3YA 4YQ5A 1X7PA 4YQJA 5FAIA 5GMBA 1UAJA 2CX8A 4YQ2A 4YVHA 3BBHA 2HA8A 3IEFA 4YQRA 3KY7A 1K3RA 1IPAA 3IC6A 3KNUA 2V3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQN A;  1P9P A;  3ONP A;  4CND A;  5GM8 A;  4YQ1 A;  4YQB A;  4FAK A;  3AI9 X;  4L69 A;  4CNE A;  4YQ3 A;  4YQK A;  4JAK A;  4YQ7 A;  4YQC A;  4YPX A;  3N4K A;  4YPZ A;  4YQA A;  1J85 A;  4YQ8 A;  4PZK A;  5CO4 A;  4YQ6 A;  3BBE A;  4J3C A;  3O7B A;  4YQS A;  3GYQ A;  3ILK A;  4X3M A;  1UAL A;  4YVG A;  4YQP A;  4YQ9 A;  1MXI A;  3N4J A;  1X7O A;  4YPW A;  1GZ0 A;  1Z85 A;  3DCM X;  4YQL A;  1UAK A;  5D9F A;  4E8B A;  2Z0Y A;  3NK6 A;  3QUV A;  4YVJ A;  4JAL A;  2QWV A;  1OY5 A;  1UAM A;  4XBO A;  4YQI A;  1NXZ A;  4MCD A;  2EGV A;  1O6D A;  3KTY A;  4CNF A;  3NK7 A;  4YQQ A;  1ZJR A;  3OII A;  2O3A A;  3BBD A;  1V6Z A;  1VHK A;  3L8U A;  5GMC A;  4X3L A;  4IG6 A;  4MCC A;  1TO0 A;  4YQ4 A;  2I6D A;  4YQG A;  4KDZ A;  2V3J A;  4YQO A;  4YVK A;  1NS5 A;  4YQD A;  3AXZ A;  4YQT A;  4H3Z A;  1V2X A;  3AIA A;  4YPY A;  4CNG A;  2EGW A;  3OIN A;  4KGN A;  4RG1 A;  4MCB A;  3OIJ A;  3E5Y A;  2QMM A;  1VH0 A;  4YQ0 A;  3KW2 A;  1VHY A;  4YVI A;  2YY8 A;  4H3Y A;  4YQ5 A;  1X7P A;  4YQJ A;  5FAI A;  5GMB A;  1UAJ A;  2CX8 A;  4YQ2 A;  4YVH A;  3BBH A;  2HA8 A;  3IEF A;  4YQR A;  3KY7 A;  1K3R A;  1IPA A;  3IC6 A;  3KNU A;  2V3K A; 
#chains in the Genus database with same CATH topology
 4YQN A;  1P9P A;  3ONP A;  4CND A;  5GM8 A;  4YQ1 A;  4YQB A;  4FAK A;  3AI9 X;  4L69 A;  4CNE A;  4YQ3 A;  4YQK A;  4JAK A;  4YQ7 A;  4YQC A;  4YPX A;  3N4K A;  4YPZ A;  4YQA A;  1J85 A;  4YQ8 A;  4PZK A;  5CO4 A;  4YQ6 A;  3BBE A;  4J3C A;  3O7B A;  4YQS A;  3GYQ A;  3ILK A;  4X3M A;  1UAL A;  4YVG A;  4YQP A;  4JWG A;  4YQ9 A;  4JWH A;  1MXI A;  3N4J A;  1X7O A;  4YPW A;  1GZ0 A;  1Z85 A;  3DCM X;  4YQL A;  1UAK A;  5D9F A;  4E8B A;  2Z0Y A;  3NK6 A;  3QUV A;  4YVJ A;  4JAL A;  2QWV A;  1OY5 A;  4JWJ A;  1UAM A;  4XBO A;  4YQI A;  1NXZ A;  4MCD A;  2EGV A;  4FMW A;  1O6D A;  3KTY A;  4JWF A;  4CNF A;  3NK7 A;  4YQQ A;  1ZJR A;  3OII A;  2O3A A;  3BBD A;  1V6Z A;  1VHK A;  3L8U A;  5GMC A;  4X3L A;  4IG6 A;  4MCC A;  1TO0 A;  4YQ4 A;  2I6D A;  4YQG A;  4KDZ A;  2V3J A;  4YQO A;  4YVK A;  1NS5 A;  4YQD A;  3AXZ A;  4YQT A;  4H3Z A;  1V2X A;  3AIA A;  4YPY A;  4CNG A;  2EGW A;  3OIN A;  4KGN A;  4RG1 A;  4MCB A;  3OIJ A;  3E5Y A;  2QMM A;  1VH0 A;  4YQ0 A;  3KW2 A;  1VHY A;  4YVI A;  2YY8 A;  4H3Y A;  4YQ5 A;  1X7P A;  4YQJ A;  5FAI A;  5GMB A;  1UAJ A;  2CX8 A;  4YQ2 A;  4YVH A;  3BBH A;  2HA8 A;  3IEF A;  4YQR A;  3KY7 A;  1K3R A;  1IPA A;  3IC6 A;  3KNU A;  2V3K A; 
#chains in the Genus database with same CATH homology
 4YQN A;  1P9P A;  3ONP A;  4CND A;  5GM8 A;  4YQ1 A;  4YQB A;  4FAK A;  3AI9 X;  4L69 A;  4CNE A;  4YQ3 A;  4YQK A;  4JAK A;  4YQ7 A;  4YQC A;  4YPX A;  3N4K A;  4YPZ A;  4YQA A;  1J85 A;  4YQ8 A;  4PZK A;  5CO4 A;  4YQ6 A;  3BBE A;  4J3C A;  3O7B A;  4YQS A;  3GYQ A;  3ILK A;  4X3M A;  1UAL A;  4YVG A;  4YQP A;  4JWG A;  4YQ9 A;  4JWH A;  1MXI A;  3N4J A;  1X7O A;  4YPW A;  1GZ0 A;  1Z85 A;  3DCM X;  4YQL A;  1UAK A;  5D9F A;  4E8B A;  2Z0Y A;  3NK6 A;  3QUV A;  4YVJ A;  4JAL A;  2QWV A;  1OY5 A;  4JWJ A;  1UAM A;  4XBO A;  4YQI A;  1NXZ A;  4MCD A;  2EGV A;  4FMW A;  1O6D A;  3KTY A;  4JWF A;  4CNF A;  3NK7 A;  4YQQ A;  1ZJR A;  3OII A;  2O3A A;  3BBD A;  1V6Z A;  1VHK A;  3L8U A;  5GMC A;  4X3L A;  4IG6 A;  4MCC A;  1TO0 A;  4YQ4 A;  2I6D A;  4YQG A;  4KDZ A;  2V3J A;  4YQO A;  4YVK A;  1NS5 A;  4YQD A;  3AXZ A;  4YQT A;  4H3Z A;  1V2X A;  3AIA A;  4YPY A;  4CNG A;  2EGW A;  3OIN A;  4KGN A;  4RG1 A;  4MCB A;  3OIJ A;  3E5Y A;  2QMM A;  1VH0 A;  4YQ0 A;  3KW2 A;  1VHY A;  4YVI A;  2YY8 A;  4H3Y A;  4YQ5 A;  1X7P A;  4YQJ A;  5FAI A;  5GMB A;  1UAJ A;  2CX8 A;  4YQ2 A;  4YVH A;  3BBH A;  2HA8 A;  3IEF A;  4YQR A;  3KY7 A;  1K3R A;  1IPA A;  3IC6 A;  3KNU A;  2V3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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