3OIJA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 2 molecules of cognate rna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
Knots found
sequence length
225
structure length
211
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule keywords Essential for mitotic growth 1
total genus 62
structure length 211
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oijA01
4H3ZA 4YQ4A 3KY7A 2V3JA 4MCCA 4YVKA 4YQAA 4YPYA 1UAKA 3GYQA 1K3RA 1NS5A 4YQIA 4YPZA 3DCMX 4YQQA 3L8UA 3AIAA 2Z0YA 4YQ6A 4MCBA 4YQ9A 4RG1A 3IC6A 4YVIA 2QWVA 4YPWA 4YQNA 4YQ2A 1GZ0A 1VHYA 3KNUA 4J3CA 4PZKA 2EGWA 1TO0A 1O6DA 4JALA 4YQ3A 3KTYA 3OIIA 1UAMA 4X3LA 3OIJA 4YQCA 4YQTA 3OINA 4YPXA 4KGNA 4YQGA 1MXIA 4XBOA 4YQ8A 5GM8A 4YQRA 1V2XA 4YQLA 1X7OA 3BBEA 2HA8A 4YVJA 3AI9X 4YQDA 4FAKA 4YQ5A 5FAIA 1VHKA 3E5YA 4YVGA 4YQ0A 1P9PA 1X7PA 3BBDA 4KDZA 1UAJA 4JAKA 3N4KA 4YQKA 1VH0A 3ILKA 4YQJA 1J85A 3QUVA 4CNFA 4E8BA 1IPAA 2QMMA 1Z85A 2EGVA 4H3YA 5D9FA 1ZJRA 3AXZA 3IEFA 4YQSA 4CNGA 4YQ1A 3NK7A 4YQ7A 5GMBA 4X3MA 2I6DA 4IG6A 4CNEA 2CX8A 1OY5A 5CO4A 1UALA 3NK6A 3KW2A 4CNDA 3BBHA 4YVHA 3ONPA 2YY8A 1V6ZA 5GMCA 1NXZA 4L69A 4MCDA 3O7BA 3N4JA 2O3AA 2V3KA 4YQPA 4YQBA 4YQOA
chains in the Genus database with same CATH superfamily
4H3ZA 4YQ4A 3KY7A 2V3JA 4MCCA 4YVKA 4YQAA 4YPYA 1UAKA 3GYQA 1K3RA 1NS5A 4YQIA 4YPZA 3DCMX 4YQQA 3L8UA 3AIAA 2Z0YA 4YQ6A 4MCBA 4YQ9A 4RG1A 3IC6A 4YVIA 2QWVA 4YPWA 4YQNA 4YQ2A 1GZ0A 1VHYA 3KNUA 4JWHA 4J3CA 4PZKA 2EGWA 1TO0A 1O6DA 4JALA 4YQ3A 3KTYA 3OIIA 1UAMA 4JWJA 4X3LA 3OIJA 4YQCA 4YQTA 3OINA 4YPXA 4KGNA 4YQGA 1MXIA 4XBOA 4YQ8A 5GM8A 4YQRA 4JWFA 1V2XA 4YQLA 1X7OA 3BBEA 2HA8A 4YVJA 3AI9X 4YQDA 4FAKA 4YQ5A 5FAIA 1VHKA 3E5YA 4YVGA 4YQ0A 4FMWA 1P9PA 1X7PA 3BBDA 4KDZA 1UAJA 4JAKA 3N4KA 4YQKA 1VH0A 3ILKA 4YQJA 1J85A 3QUVA 4CNFA 4E8BA 1IPAA 2QMMA 1Z85A 2EGVA 4H3YA 5D9FA 1ZJRA 3AXZA 3IEFA 4YQSA 4CNGA 4YQ1A 3NK7A 4YQ7A 5GMBA 4X3MA 2I6DA 4IG6A 4CNEA 2CX8A 1OY5A 5CO4A 4JWGA 1UALA 3NK6A 3KW2A 4CNDA 3BBHA 4YVHA 3ONPA 2YY8A 1V6ZA 5GMCA 1NXZA 4L69A 4MCDA 3O7BA 3N4JA 2O3AA 2V3KA 4YQPA 4YQBA 4YQOA
chains in the Genus database with same CATH topology
4H3ZA 4YQ4A 3KY7A 2V3JA 4MCCA 4YVKA 4YQAA 4YPYA 1UAKA 3GYQA 1K3RA 1NS5A 4YQIA 4YPZA 3DCMX 4YQQA 3L8UA 3AIAA 2Z0YA 4YQ6A 4MCBA 4YQ9A 4RG1A 3IC6A 4YVIA 2QWVA 4YPWA 4YQNA 4YQ2A 1GZ0A 1VHYA 3KNUA 4JWHA 4J3CA 4PZKA 2EGWA 1TO0A 1O6DA 4JALA 4YQ3A 3KTYA 3OIIA 1UAMA 4JWJA 4X3LA 3OIJA 4YQCA 4YQTA 3OINA 4YPXA 4KGNA 4YQGA 1MXIA 4XBOA 4YQ8A 5GM8A 4YQRA 4JWFA 1V2XA 4YQLA 1X7OA 3BBEA 2HA8A 4YVJA 3AI9X 4YQDA 4FAKA 4YQ5A 5FAIA 1VHKA 3E5YA 4YVGA 4YQ0A 4FMWA 1P9PA 1X7PA 3BBDA 4KDZA 1UAJA 4JAKA 3N4KA 4YQKA 1VH0A 3ILKA 4YQJA 1J85A 3QUVA 4CNFA 4E8BA 1IPAA 2QMMA 1Z85A 2EGVA 4H3YA 5D9FA 1ZJRA 3AXZA 3IEFA 4YQSA 4CNGA 4YQ1A 3NK7A 4YQ7A 5GMBA 4X3MA 2I6DA 4IG6A 4CNEA 2CX8A 1OY5A 5CO4A 4JWGA 1UALA 3NK6A 3KW2A 4CNDA 3BBHA 4YVHA 3ONPA 2YY8A 1V6ZA 5GMCA 1NXZA 4L69A 4MCDA 3O7BA 3N4JA 2O3AA 2V3KA 4YQPA 4YQBA 4YQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H3Z A;  4YQ4 A;  3KY7 A;  2V3J A;  4MCC A;  4YVK A;  4YQA A;  4YPY A;  1UAK A;  3GYQ A;  1K3R A;  1NS5 A;  4YQI A;  4YPZ A;  3DCM X;  4YQQ A;  3L8U A;  3AIA A;  2Z0Y A;  4YQ6 A;  4MCB A;  4YQ9 A;  4RG1 A;  3IC6 A;  4YVI A;  2QWV A;  4YPW A;  4YQN A;  4YQ2 A;  1GZ0 A;  1VHY A;  3KNU A;  4J3C A;  4PZK A;  2EGW A;  1TO0 A;  1O6D A;  4JAL A;  4YQ3 A;  3KTY A;  3OII A;  1UAM A;  4X3L A;  3OIJ A;  4YQC A;  4YQT A;  3OIN A;  4YPX A;  4KGN A;  4YQG A;  1MXI A;  4XBO A;  4YQ8 A;  5GM8 A;  4YQR A;  1V2X A;  4YQL A;  1X7O A;  3BBE A;  2HA8 A;  4YVJ A;  3AI9 X;  4YQD A;  4FAK A;  4YQ5 A;  5FAI A;  1VHK A;  3E5Y A;  4YVG A;  4YQ0 A;  1P9P A;  1X7P A;  3BBD A;  4KDZ A;  1UAJ A;  4JAK A;  3N4K A;  4YQK A;  1VH0 A;  3ILK A;  4YQJ A;  1J85 A;  3QUV A;  4CNF A;  4E8B A;  1IPA A;  2QMM A;  1Z85 A;  2EGV A;  4H3Y A;  5D9F A;  1ZJR A;  3AXZ A;  3IEF A;  4YQS A;  4CNG A;  4YQ1 A;  3NK7 A;  4YQ7 A;  5GMB A;  4X3M A;  2I6D A;  4IG6 A;  4CNE A;  2CX8 A;  1OY5 A;  5CO4 A;  1UAL A;  3NK6 A;  3KW2 A;  4CND A;  3BBH A;  4YVH A;  3ONP A;  2YY8 A;  1V6Z A;  5GMC A;  1NXZ A;  4L69 A;  4MCD A;  3O7B A;  3N4J A;  2O3A A;  2V3K A;  4YQP A;  4YQB A;  4YQO A; 
#chains in the Genus database with same CATH topology
 4H3Z A;  4YQ4 A;  3KY7 A;  2V3J A;  4MCC A;  4YVK A;  4YQA A;  4YPY A;  1UAK A;  3GYQ A;  1K3R A;  1NS5 A;  4YQI A;  4YPZ A;  3DCM X;  4YQQ A;  3L8U A;  3AIA A;  2Z0Y A;  4YQ6 A;  4MCB A;  4YQ9 A;  4RG1 A;  3IC6 A;  4YVI A;  2QWV A;  4YPW A;  4YQN A;  4YQ2 A;  1GZ0 A;  1VHY A;  3KNU A;  4JWH A;  4J3C A;  4PZK A;  2EGW A;  1TO0 A;  1O6D A;  4JAL A;  4YQ3 A;  3KTY A;  3OII A;  1UAM A;  4JWJ A;  4X3L A;  3OIJ A;  4YQC A;  4YQT A;  3OIN A;  4YPX A;  4KGN A;  4YQG A;  1MXI A;  4XBO A;  4YQ8 A;  5GM8 A;  4YQR A;  4JWF A;  1V2X A;  4YQL A;  1X7O A;  3BBE A;  2HA8 A;  4YVJ A;  3AI9 X;  4YQD A;  4FAK A;  4YQ5 A;  5FAI A;  1VHK A;  3E5Y A;  4YVG A;  4YQ0 A;  4FMW A;  1P9P A;  1X7P A;  3BBD A;  4KDZ A;  1UAJ A;  4JAK A;  3N4K A;  4YQK A;  1VH0 A;  3ILK A;  4YQJ A;  1J85 A;  3QUV A;  4CNF A;  4E8B A;  1IPA A;  2QMM A;  1Z85 A;  2EGV A;  4H3Y A;  5D9F A;  1ZJR A;  3AXZ A;  3IEF A;  4YQS A;  4CNG A;  4YQ1 A;  3NK7 A;  4YQ7 A;  5GMB A;  4X3M A;  2I6D A;  4IG6 A;  4CNE A;  2CX8 A;  1OY5 A;  5CO4 A;  4JWG A;  1UAL A;  3NK6 A;  3KW2 A;  4CND A;  3BBH A;  4YVH A;  3ONP A;  2YY8 A;  1V6Z A;  5GMC A;  1NXZ A;  4L69 A;  4MCD A;  3O7B A;  3N4J A;  2O3A A;  2V3K A;  4YQP A;  4YQB A;  4YQO A; 
#chains in the Genus database with same CATH homology
 4H3Z A;  4YQ4 A;  3KY7 A;  2V3J A;  4MCC A;  4YVK A;  4YQA A;  4YPY A;  1UAK A;  3GYQ A;  1K3R A;  1NS5 A;  4YQI A;  4YPZ A;  3DCM X;  4YQQ A;  3L8U A;  3AIA A;  2Z0Y A;  4YQ6 A;  4MCB A;  4YQ9 A;  4RG1 A;  3IC6 A;  4YVI A;  2QWV A;  4YPW A;  4YQN A;  4YQ2 A;  1GZ0 A;  1VHY A;  3KNU A;  4JWH A;  4J3C A;  4PZK A;  2EGW A;  1TO0 A;  1O6D A;  4JAL A;  4YQ3 A;  3KTY A;  3OII A;  1UAM A;  4JWJ A;  4X3L A;  3OIJ A;  4YQC A;  4YQT A;  3OIN A;  4YPX A;  4KGN A;  4YQG A;  1MXI A;  4XBO A;  4YQ8 A;  5GM8 A;  4YQR A;  4JWF A;  1V2X A;  4YQL A;  1X7O A;  3BBE A;  2HA8 A;  4YVJ A;  3AI9 X;  4YQD A;  4FAK A;  4YQ5 A;  5FAI A;  1VHK A;  3E5Y A;  4YVG A;  4YQ0 A;  4FMW A;  1P9P A;  1X7P A;  3BBD A;  4KDZ A;  1UAJ A;  4JAK A;  3N4K A;  4YQK A;  1VH0 A;  3ILK A;  4YQJ A;  1J85 A;  3QUV A;  4CNF A;  4E8B A;  1IPA A;  2QMM A;  1Z85 A;  2EGV A;  4H3Y A;  5D9F A;  1ZJR A;  3AXZ A;  3IEF A;  4YQS A;  4CNG A;  4YQ1 A;  3NK7 A;  4YQ7 A;  5GMB A;  4X3M A;  2I6D A;  4IG6 A;  4CNE A;  2CX8 A;  1OY5 A;  5CO4 A;  4JWG A;  1UAL A;  3NK6 A;  3KW2 A;  4CND A;  3BBH A;  4YVH A;  3ONP A;  2YY8 A;  1V6Z A;  5GMC A;  1NXZ A;  4L69 A;  4MCD A;  3O7B A;  3N4J A;  2O3A A;  2V3K A;  4YQP A;  4YQB A;  4YQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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