3OIJA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 2 molecules of cognate rna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
Knots found
sequence length
225
structure length
211
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 62
structure length 211
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oijA01
4YVGA 1UAKA 3AIAA 1P9PA 1ZJRA 1GZ0A 2O3AA 2QMMA 3N4JA 4MCBA 4YQQA 2Z0YA 5D9FA 4YQCA 2V3KA 4YQ1A 4YQ6A 4YPXA 1V2XA 4MCCA 1UALA 3KW2A 3OIIA 4YQ8A 1V6ZA 4YQSA 1OY5A 4YVIA 2V3JA 3E5YA 4J3CA 1J85A 5CO4A 4YPYA 4YQGA 4YQ0A 4MCDA 4JALA 5GMCA 1VHYA 4YVJA 4YVHA 1Z85A 4H3YA 5FAIA 3ONPA 4FAKA 3DCMX 4YQOA 4YQDA 3NK7A 4YQPA 3IEFA 4JAKA 4YQ7A 4YQIA 4CNEA 2I6DA 1UAJA 4YQKA 4PZKA 1MXIA 4YQLA 4E8BA 4YQNA 1TO0A 1VHKA 2QWVA 3KNUA 1NXZA 4X3MA 4YQ5A 2EGVA 4YPZA 3AXZA 1IPAA 3KY7A 4CNGA 3L8UA 1O6DA 4YQAA 4CNFA 3O7BA 1UAMA 4KDZA 4YQTA 3BBDA 4YQJA 4YQBA 4YPWA 2HA8A 3OINA 4H3ZA 3AI9X 4YQ9A 3GYQA 5GM8A 3BBEA 4XBOA 4CNDA 3QUVA 2YY8A 1K3RA 1VH0A 4RG1A 1X7PA 4X3LA 3NK6A 4YQ4A 4IG6A 3IC6A 4YVKA 2CX8A 4YQRA 3OIJA 5GMBA 4YQ2A 2EGWA 3N4KA 4KGNA 3ILKA 3BBHA 3KTYA 4L69A 1NS5A 1X7OA 4YQ3A
chains in the Genus database with same CATH superfamily
4YVGA 1UAKA 3AIAA 1P9PA 1ZJRA 1GZ0A 2O3AA 2QMMA 3N4JA 4MCBA 4YQQA 2Z0YA 5D9FA 4YQCA 4FMWA 2V3KA 4YQ1A 4YQ6A 4YPXA 1V2XA 4MCCA 1UALA 3KW2A 3OIIA 4YQ8A 1V6ZA 4YQSA 1OY5A 4YVIA 2V3JA 3E5YA 4J3CA 1J85A 5CO4A 4YPYA 4YQGA 4YQ0A 4MCDA 4JALA 5GMCA 1VHYA 4YVJA 4YVHA 1Z85A 4H3YA 5FAIA 3ONPA 4FAKA 3DCMX 4YQOA 4YQDA 3NK7A 4YQPA 3IEFA 4JAKA 4JWFA 4YQ7A 4YQIA 4CNEA 2I6DA 1UAJA 4YQKA 4PZKA 1MXIA 4YQLA 4E8BA 4YQNA 1TO0A 1VHKA 2QWVA 3KNUA 1NXZA 4X3MA 4YQ5A 2EGVA 4YPZA 3AXZA 1IPAA 3KY7A 4CNGA 3L8UA 1O6DA 4YQAA 4CNFA 3O7BA 1UAMA 4KDZA 4JWJA 4YQTA 3BBDA 4YQJA 4YQBA 4YPWA 2HA8A 3OINA 4H3ZA 3AI9X 4YQ9A 3GYQA 5GM8A 3BBEA 4XBOA 4CNDA 3QUVA 2YY8A 1K3RA 4JWHA 1VH0A 4RG1A 1X7PA 4X3LA 3NK6A 4YQ4A 4IG6A 3IC6A 4YVKA 2CX8A 4YQRA 3OIJA 5GMBA 4YQ2A 2EGWA 3N4KA 4KGNA 3ILKA 3BBHA 3KTYA 4L69A 1NS5A 4JWGA 1X7OA 4YQ3A
chains in the Genus database with same CATH topology
4YVGA 1UAKA 3AIAA 1P9PA 1ZJRA 1GZ0A 2O3AA 2QMMA 3N4JA 4MCBA 4YQQA 2Z0YA 5D9FA 4YQCA 4FMWA 2V3KA 4YQ1A 4YQ6A 4YPXA 1V2XA 4MCCA 1UALA 3KW2A 3OIIA 4YQ8A 1V6ZA 4YQSA 1OY5A 4YVIA 2V3JA 3E5YA 4J3CA 1J85A 5CO4A 4YPYA 4YQGA 4YQ0A 4MCDA 4JALA 5GMCA 1VHYA 4YVJA 4YVHA 1Z85A 4H3YA 5FAIA 3ONPA 4FAKA 3DCMX 4YQOA 4YQDA 3NK7A 4YQPA 3IEFA 4JAKA 4JWFA 4YQ7A 4YQIA 4CNEA 2I6DA 1UAJA 4YQKA 4PZKA 1MXIA 4YQLA 4E8BA 4YQNA 1TO0A 1VHKA 2QWVA 3KNUA 1NXZA 4X3MA 4YQ5A 2EGVA 4YPZA 3AXZA 1IPAA 3KY7A 4CNGA 3L8UA 1O6DA 4YQAA 4CNFA 3O7BA 1UAMA 4KDZA 4JWJA 4YQTA 3BBDA 4YQJA 4YQBA 4YPWA 2HA8A 3OINA 4H3ZA 3AI9X 4YQ9A 3GYQA 5GM8A 3BBEA 4XBOA 4CNDA 3QUVA 2YY8A 1K3RA 4JWHA 1VH0A 4RG1A 1X7PA 4X3LA 3NK6A 4YQ4A 4IG6A 3IC6A 4YVKA 2CX8A 4YQRA 3OIJA 5GMBA 4YQ2A 2EGWA 3N4KA 4KGNA 3ILKA 3BBHA 3KTYA 4L69A 1NS5A 4JWGA 1X7OA 4YQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVG A;  1UAK A;  3AIA A;  1P9P A;  1ZJR A;  1GZ0 A;  2O3A A;  2QMM A;  3N4J A;  4MCB A;  4YQQ A;  2Z0Y A;  5D9F A;  4YQC A;  2V3K A;  4YQ1 A;  4YQ6 A;  4YPX A;  1V2X A;  4MCC A;  1UAL A;  3KW2 A;  3OII A;  4YQ8 A;  1V6Z A;  4YQS A;  1OY5 A;  4YVI A;  2V3J A;  3E5Y A;  4J3C A;  1J85 A;  5CO4 A;  4YPY A;  4YQG A;  4YQ0 A;  4MCD A;  4JAL A;  5GMC A;  1VHY A;  4YVJ A;  4YVH A;  1Z85 A;  4H3Y A;  5FAI A;  3ONP A;  4FAK A;  3DCM X;  4YQO A;  4YQD A;  3NK7 A;  4YQP A;  3IEF A;  4JAK A;  4YQ7 A;  4YQI A;  4CNE A;  2I6D A;  1UAJ A;  4YQK A;  4PZK A;  1MXI A;  4YQL A;  4E8B A;  4YQN A;  1TO0 A;  1VHK A;  2QWV A;  3KNU A;  1NXZ A;  4X3M A;  4YQ5 A;  2EGV A;  4YPZ A;  3AXZ A;  1IPA A;  3KY7 A;  4CNG A;  3L8U A;  1O6D A;  4YQA A;  4CNF A;  3O7B A;  1UAM A;  4KDZ A;  4YQT A;  3BBD A;  4YQJ A;  4YQB A;  4YPW A;  2HA8 A;  3OIN A;  4H3Z A;  3AI9 X;  4YQ9 A;  3GYQ A;  5GM8 A;  3BBE A;  4XBO A;  4CND A;  3QUV A;  2YY8 A;  1K3R A;  1VH0 A;  4RG1 A;  1X7P A;  4X3L A;  3NK6 A;  4YQ4 A;  4IG6 A;  3IC6 A;  4YVK A;  2CX8 A;  4YQR A;  3OIJ A;  5GMB A;  4YQ2 A;  2EGW A;  3N4K A;  4KGN A;  3ILK A;  3BBH A;  3KTY A;  4L69 A;  1NS5 A;  1X7O A;  4YQ3 A; 
#chains in the Genus database with same CATH topology
 4YVG A;  1UAK A;  3AIA A;  1P9P A;  1ZJR A;  1GZ0 A;  2O3A A;  2QMM A;  3N4J A;  4MCB A;  4YQQ A;  2Z0Y A;  5D9F A;  4YQC A;  4FMW A;  2V3K A;  4YQ1 A;  4YQ6 A;  4YPX A;  1V2X A;  4MCC A;  1UAL A;  3KW2 A;  3OII A;  4YQ8 A;  1V6Z A;  4YQS A;  1OY5 A;  4YVI A;  2V3J A;  3E5Y A;  4J3C A;  1J85 A;  5CO4 A;  4YPY A;  4YQG A;  4YQ0 A;  4MCD A;  4JAL A;  5GMC A;  1VHY A;  4YVJ A;  4YVH A;  1Z85 A;  4H3Y A;  5FAI A;  3ONP A;  4FAK A;  3DCM X;  4YQO A;  4YQD A;  3NK7 A;  4YQP A;  3IEF A;  4JAK A;  4JWF A;  4YQ7 A;  4YQI A;  4CNE A;  2I6D A;  1UAJ A;  4YQK A;  4PZK A;  1MXI A;  4YQL A;  4E8B A;  4YQN A;  1TO0 A;  1VHK A;  2QWV A;  3KNU A;  1NXZ A;  4X3M A;  4YQ5 A;  2EGV A;  4YPZ A;  3AXZ A;  1IPA A;  3KY7 A;  4CNG A;  3L8U A;  1O6D A;  4YQA A;  4CNF A;  3O7B A;  1UAM A;  4KDZ A;  4JWJ A;  4YQT A;  3BBD A;  4YQJ A;  4YQB A;  4YPW A;  2HA8 A;  3OIN A;  4H3Z A;  3AI9 X;  4YQ9 A;  3GYQ A;  5GM8 A;  3BBE A;  4XBO A;  4CND A;  3QUV A;  2YY8 A;  1K3R A;  4JWH A;  1VH0 A;  4RG1 A;  1X7P A;  4X3L A;  3NK6 A;  4YQ4 A;  4IG6 A;  3IC6 A;  4YVK A;  2CX8 A;  4YQR A;  3OIJ A;  5GMB A;  4YQ2 A;  2EGW A;  3N4K A;  4KGN A;  3ILK A;  3BBH A;  3KTY A;  4L69 A;  1NS5 A;  4JWG A;  1X7O A;  4YQ3 A; 
#chains in the Genus database with same CATH homology
 4YVG A;  1UAK A;  3AIA A;  1P9P A;  1ZJR A;  1GZ0 A;  2O3A A;  2QMM A;  3N4J A;  4MCB A;  4YQQ A;  2Z0Y A;  5D9F A;  4YQC A;  4FMW A;  2V3K A;  4YQ1 A;  4YQ6 A;  4YPX A;  1V2X A;  4MCC A;  1UAL A;  3KW2 A;  3OII A;  4YQ8 A;  1V6Z A;  4YQS A;  1OY5 A;  4YVI A;  2V3J A;  3E5Y A;  4J3C A;  1J85 A;  5CO4 A;  4YPY A;  4YQG A;  4YQ0 A;  4MCD A;  4JAL A;  5GMC A;  1VHY A;  4YVJ A;  4YVH A;  1Z85 A;  4H3Y A;  5FAI A;  3ONP A;  4FAK A;  3DCM X;  4YQO A;  4YQD A;  3NK7 A;  4YQP A;  3IEF A;  4JAK A;  4JWF A;  4YQ7 A;  4YQI A;  4CNE A;  2I6D A;  1UAJ A;  4YQK A;  4PZK A;  1MXI A;  4YQL A;  4E8B A;  4YQN A;  1TO0 A;  1VHK A;  2QWV A;  3KNU A;  1NXZ A;  4X3M A;  4YQ5 A;  2EGV A;  4YPZ A;  3AXZ A;  1IPA A;  3KY7 A;  4CNG A;  3L8U A;  1O6D A;  4YQA A;  4CNF A;  3O7B A;  1UAM A;  4KDZ A;  4JWJ A;  4YQT A;  3BBD A;  4YQJ A;  4YQB A;  4YPW A;  2HA8 A;  3OIN A;  4H3Z A;  3AI9 X;  4YQ9 A;  3GYQ A;  5GM8 A;  3BBE A;  4XBO A;  4CND A;  3QUV A;  2YY8 A;  1K3R A;  4JWH A;  1VH0 A;  4RG1 A;  1X7P A;  4X3L A;  3NK6 A;  4YQ4 A;  4IG6 A;  3IC6 A;  4YVK A;  2CX8 A;  4YQR A;  3OIJ A;  5GMB A;  4YQ2 A;  2EGW A;  3N4K A;  4KGN A;  3ILK A;  3BBH A;  3KTY A;  4L69 A;  1NS5 A;  4JWG A;  1X7O A;  4YQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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