3OINA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 1 molecule of cognate rna
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
225
structure length
217
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 66
structure length 217
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oinA01
1VHYA 4YQQA 4X3LA 4YPZA 2Z0YA 4YQOA 2EGWA 1V6ZA 4YQDA 1V2XA 5CO4A 1IPAA 4KGNA 4YQ6A 4YQ7A 1P9PA 1NXZA 1GZ0A 3OIJA 4YQ8A 1UAKA 3KTYA 4RG1A 4YQ5A 2CX8A 4YQIA 1OY5A 4YQTA 3KW2A 4YQJA 4YQ0A 1VH0A 4JAKA 1UALA 4YQRA 4CNGA 4JALA 5GMCA 4YQ4A 3ILKA 2O3AA 4YQAA 4YQGA 4CNEA 3NK7A 1K3RA 4PZKA 3IEFA 4CNDA 2YY8A 4MCBA 1VHKA 3N4KA 2HA8A 3AIAA 3AI9X 5GMBA 1X7OA 4YQLA 4H3ZA 4KDZA 4YQCA 4YVJA 4J3CA 4YQSA 5D9FA 3O7BA 4E8BA 4L69A 4YPYA 2QMMA 3BBDA 4YVHA 4YQ3A 4MCCA 4YVKA 5FAIA 4YQ2A 4YQ1A 3N4JA 3E5YA 4X3MA 1O6DA 4YPWA 1NS5A 3DCMX 4YVGA 3KY7A 3QUVA 1UAMA 3NK6A 3BBHA 4YQBA 1ZJRA 2V3JA 3KNUA 4CNFA 2I6DA 3BBEA 4YQNA 4YPXA 4H3YA 1TO0A 3L8UA 3OIIA 5GM8A 4MCDA 4FAKA 3ONPA 3OINA 4IG6A 4YQKA 2V3KA 3AXZA 3IC6A 4YQPA 1UAJA 4YQ9A 4YVIA 1J85A 1X7PA 1Z85A 4XBOA 1MXIA 2QWVA 3GYQA 2EGVA
chains in the Genus database with same CATH superfamily
1VHYA 4YQQA 4X3LA 4YPZA 2Z0YA 4YQOA 2EGWA 1V6ZA 4YQDA 1V2XA 5CO4A 1IPAA 4KGNA 4YQ6A 4YQ7A 1P9PA 1NXZA 1GZ0A 3OIJA 4JWHA 4FMWA 4YQ8A 1UAKA 3KTYA 4RG1A 4YQ5A 2CX8A 4YQIA 1OY5A 4YQTA 3KW2A 4YQJA 4YQ0A 1VH0A 4JAKA 1UALA 4YQRA 4CNGA 4JALA 4JWJA 5GMCA 4YQ4A 3ILKA 2O3AA 4YQAA 4YQGA 4CNEA 3NK7A 1K3RA 4PZKA 3IEFA 4CNDA 2YY8A 4MCBA 1VHKA 3N4KA 2HA8A 3AIAA 3AI9X 5GMBA 1X7OA 4YQLA 4H3ZA 4KDZA 4YQCA 4YVJA 4J3CA 4YQSA 5D9FA 3O7BA 4E8BA 4L69A 4YPYA 2QMMA 3BBDA 4YVHA 4YQ3A 4MCCA 4YVKA 5FAIA 4YQ2A 4YQ1A 3N4JA 3E5YA 4X3MA 1O6DA 4YPWA 1NS5A 3DCMX 4YVGA 3KY7A 3QUVA 1UAMA 3NK6A 3BBHA 4YQBA 1ZJRA 2V3JA 3KNUA 4CNFA 2I6DA 3BBEA 4YQNA 4YPXA 4H3YA 1TO0A 3L8UA 3OIIA 5GM8A 4MCDA 4FAKA 3ONPA 3OINA 4IG6A 4YQKA 2V3KA 3AXZA 3IC6A 4YQPA 1UAJA 4JWGA 4YQ9A 4YVIA 1J85A 1X7PA 1Z85A 4XBOA 1MXIA 2QWVA 3GYQA 4JWFA 2EGVA
chains in the Genus database with same CATH topology
1VHYA 4YQQA 4X3LA 4YPZA 2Z0YA 4YQOA 2EGWA 1V6ZA 4YQDA 1V2XA 5CO4A 1IPAA 4KGNA 4YQ6A 4YQ7A 1P9PA 1NXZA 1GZ0A 3OIJA 4JWHA 4FMWA 4YQ8A 1UAKA 3KTYA 4RG1A 4YQ5A 2CX8A 4YQIA 1OY5A 4YQTA 3KW2A 4YQJA 4YQ0A 1VH0A 4JAKA 1UALA 4YQRA 4CNGA 4JALA 4JWJA 5GMCA 4YQ4A 3ILKA 2O3AA 4YQAA 4YQGA 4CNEA 3NK7A 1K3RA 4PZKA 3IEFA 4CNDA 2YY8A 4MCBA 1VHKA 3N4KA 2HA8A 3AIAA 3AI9X 5GMBA 1X7OA 4YQLA 4H3ZA 4KDZA 4YQCA 4YVJA 4J3CA 4YQSA 5D9FA 3O7BA 4E8BA 4L69A 4YPYA 2QMMA 3BBDA 4YVHA 4YQ3A 4MCCA 4YVKA 5FAIA 4YQ2A 4YQ1A 3N4JA 3E5YA 4X3MA 1O6DA 4YPWA 1NS5A 3DCMX 4YVGA 3KY7A 3QUVA 1UAMA 3NK6A 3BBHA 4YQBA 1ZJRA 2V3JA 3KNUA 4CNFA 2I6DA 3BBEA 4YQNA 4YPXA 4H3YA 1TO0A 3L8UA 3OIIA 5GM8A 4MCDA 4FAKA 3ONPA 3OINA 4IG6A 4YQKA 2V3KA 3AXZA 3IC6A 4YQPA 1UAJA 4JWGA 4YQ9A 4YVIA 1J85A 1X7PA 1Z85A 4XBOA 1MXIA 2QWVA 3GYQA 4JWFA 2EGVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VHY A;  4YQQ A;  4X3L A;  4YPZ A;  2Z0Y A;  4YQO A;  2EGW A;  1V6Z A;  4YQD A;  1V2X A;  5CO4 A;  1IPA A;  4KGN A;  4YQ6 A;  4YQ7 A;  1P9P A;  1NXZ A;  1GZ0 A;  3OIJ A;  4YQ8 A;  1UAK A;  3KTY A;  4RG1 A;  4YQ5 A;  2CX8 A;  4YQI A;  1OY5 A;  4YQT A;  3KW2 A;  4YQJ A;  4YQ0 A;  1VH0 A;  4JAK A;  1UAL A;  4YQR A;  4CNG A;  4JAL A;  5GMC A;  4YQ4 A;  3ILK A;  2O3A A;  4YQA A;  4YQG A;  4CNE A;  3NK7 A;  1K3R A;  4PZK A;  3IEF A;  4CND A;  2YY8 A;  4MCB A;  1VHK A;  3N4K A;  2HA8 A;  3AIA A;  3AI9 X;  5GMB A;  1X7O A;  4YQL A;  4H3Z A;  4KDZ A;  4YQC A;  4YVJ A;  4J3C A;  4YQS A;  5D9F A;  3O7B A;  4E8B A;  4L69 A;  4YPY A;  2QMM A;  3BBD A;  4YVH A;  4YQ3 A;  4MCC A;  4YVK A;  5FAI A;  4YQ2 A;  4YQ1 A;  3N4J A;  3E5Y A;  4X3M A;  1O6D A;  4YPW A;  1NS5 A;  3DCM X;  4YVG A;  3KY7 A;  3QUV A;  1UAM A;  3NK6 A;  3BBH A;  4YQB A;  1ZJR A;  2V3J A;  3KNU A;  4CNF A;  2I6D A;  3BBE A;  4YQN A;  4YPX A;  4H3Y A;  1TO0 A;  3L8U A;  3OII A;  5GM8 A;  4MCD A;  4FAK A;  3ONP A;  3OIN A;  4IG6 A;  4YQK A;  2V3K A;  3AXZ A;  3IC6 A;  4YQP A;  1UAJ A;  4YQ9 A;  4YVI A;  1J85 A;  1X7P A;  1Z85 A;  4XBO A;  1MXI A;  2QWV A;  3GYQ A;  2EGV A; 
#chains in the Genus database with same CATH topology
 1VHY A;  4YQQ A;  4X3L A;  4YPZ A;  2Z0Y A;  4YQO A;  2EGW A;  1V6Z A;  4YQD A;  1V2X A;  5CO4 A;  1IPA A;  4KGN A;  4YQ6 A;  4YQ7 A;  1P9P A;  1NXZ A;  1GZ0 A;  3OIJ A;  4JWH A;  4FMW A;  4YQ8 A;  1UAK A;  3KTY A;  4RG1 A;  4YQ5 A;  2CX8 A;  4YQI A;  1OY5 A;  4YQT A;  3KW2 A;  4YQJ A;  4YQ0 A;  1VH0 A;  4JAK A;  1UAL A;  4YQR A;  4CNG A;  4JAL A;  4JWJ A;  5GMC A;  4YQ4 A;  3ILK A;  2O3A A;  4YQA A;  4YQG A;  4CNE A;  3NK7 A;  1K3R A;  4PZK A;  3IEF A;  4CND A;  2YY8 A;  4MCB A;  1VHK A;  3N4K A;  2HA8 A;  3AIA A;  3AI9 X;  5GMB A;  1X7O A;  4YQL A;  4H3Z A;  4KDZ A;  4YQC A;  4YVJ A;  4J3C A;  4YQS A;  5D9F A;  3O7B A;  4E8B A;  4L69 A;  4YPY A;  2QMM A;  3BBD A;  4YVH A;  4YQ3 A;  4MCC A;  4YVK A;  5FAI A;  4YQ2 A;  4YQ1 A;  3N4J A;  3E5Y A;  4X3M A;  1O6D A;  4YPW A;  1NS5 A;  3DCM X;  4YVG A;  3KY7 A;  3QUV A;  1UAM A;  3NK6 A;  3BBH A;  4YQB A;  1ZJR A;  2V3J A;  3KNU A;  4CNF A;  2I6D A;  3BBE A;  4YQN A;  4YPX A;  4H3Y A;  1TO0 A;  3L8U A;  3OII A;  5GM8 A;  4MCD A;  4FAK A;  3ONP A;  3OIN A;  4IG6 A;  4YQK A;  2V3K A;  3AXZ A;  3IC6 A;  4YQP A;  1UAJ A;  4JWG A;  4YQ9 A;  4YVI A;  1J85 A;  1X7P A;  1Z85 A;  4XBO A;  1MXI A;  2QWV A;  3GYQ A;  4JWF A;  2EGV A; 
#chains in the Genus database with same CATH homology
 1VHY A;  4YQQ A;  4X3L A;  4YPZ A;  2Z0Y A;  4YQO A;  2EGW A;  1V6Z A;  4YQD A;  1V2X A;  5CO4 A;  1IPA A;  4KGN A;  4YQ6 A;  4YQ7 A;  1P9P A;  1NXZ A;  1GZ0 A;  3OIJ A;  4JWH A;  4FMW A;  4YQ8 A;  1UAK A;  3KTY A;  4RG1 A;  4YQ5 A;  2CX8 A;  4YQI A;  1OY5 A;  4YQT A;  3KW2 A;  4YQJ A;  4YQ0 A;  1VH0 A;  4JAK A;  1UAL A;  4YQR A;  4CNG A;  4JAL A;  4JWJ A;  5GMC A;  4YQ4 A;  3ILK A;  2O3A A;  4YQA A;  4YQG A;  4CNE A;  3NK7 A;  1K3R A;  4PZK A;  3IEF A;  4CND A;  2YY8 A;  4MCB A;  1VHK A;  3N4K A;  2HA8 A;  3AIA A;  3AI9 X;  5GMB A;  1X7O A;  4YQL A;  4H3Z A;  4KDZ A;  4YQC A;  4YVJ A;  4J3C A;  4YQS A;  5D9F A;  3O7B A;  4E8B A;  4L69 A;  4YPY A;  2QMM A;  3BBD A;  4YVH A;  4YQ3 A;  4MCC A;  4YVK A;  5FAI A;  4YQ2 A;  4YQ1 A;  3N4J A;  3E5Y A;  4X3M A;  1O6D A;  4YPW A;  1NS5 A;  3DCM X;  4YVG A;  3KY7 A;  3QUV A;  1UAM A;  3NK6 A;  3BBH A;  4YQB A;  1ZJR A;  2V3J A;  3KNU A;  4CNF A;  2I6D A;  3BBE A;  4YQN A;  4YPX A;  4H3Y A;  1TO0 A;  3L8U A;  3OII A;  5GM8 A;  4MCD A;  4FAK A;  3ONP A;  3OIN A;  4IG6 A;  4YQK A;  2V3K A;  3AXZ A;  3IC6 A;  4YQP A;  1UAJ A;  4JWG A;  4YQ9 A;  4YVI A;  1J85 A;  1X7P A;  1Z85 A;  4XBO A;  1MXI A;  2QWV A;  3GYQ A;  4JWF A;  2EGV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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