4CNGA

Crystal structure of sulfolobus acidocaldarius trmj in complex with s-adenosyl-l-homocysteine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
Knots found
sequence length
156
structure length
156
Chain Sequence
MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKGSEVIEKMMKITNNFDDAIRDVDLKIATSSIADIKGDLLRKSIRPIDLERLIKDKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus acidocaldarius
molecule keywords SPOU RRNA METHYLASE
total genus 51
structure length 156
sequence length 156
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cngA00
1VHYA 3OIJA 5D9FA 2HA8A 3KTYA 4J3CA 3AIAA 4YQNA 4YVJA 1V6ZA 4XBOA 2YY8A 5FAIA 3GYQA 3N4JA 3QUVA 4X3MA 4YQ9A 4YQ4A 2V3JA 4YPWA 4YQRA 4CNDA 2EGVA 4E8BA 4CNGA 4H3YA 4YQCA 3BBDA 3AI9X 4YQDA 1X7PA 2I6DA 4JAKA 1NS5A 1UAMA 3O7BA 4YVHA 3NK6A 4KGNA 1Z85A 3BBHA 3OIIA 4YQQA 5CO4A 1K3RA 2EGWA 4L69A 1V2XA 3BBEA 4YQOA 4YQBA 1X7OA 4PZKA 4YQIA 1O6DA 4YQPA 1NXZA 5GM8A 4YQ2A 3KY7A 3KW2A 3N4KA 4RG1A 3ILKA 1UALA 4MCBA 2V3KA 1OY5A 4YQ3A 4YVGA 1MXIA 2Z0YA 4YQSA 3NK7A 3L8UA 2CX8A 4H3ZA 3IEFA 4MCDA 4YPYA 4YQ8A 4YQGA 1VHKA 4IG6A 4YQ6A 4YQAA 4YQ7A 4YQLA 3OINA 3KNUA 3AXZA 3IC6A 4YPZA 4YVIA 1UAKA 4MCCA 4YQ1A 2QWVA 4JALA 2QMMA 4YVKA 1J85A 1UAJA 4KDZA 1P9PA 4YQTA 4CNFA 4X3LA 2O3AA 3E5YA 4YQ0A 4YPXA 1VH0A 3ONPA 5GMBA 4YQJA 1IPAA 4CNEA 1GZ0A 5GMCA 1ZJRA 3DCMX 4YQKA 1TO0A 4YQ5A 4FAKA
chains in the Genus database with same CATH superfamily
1VHYA 3OIJA 5D9FA 4FMWA 2HA8A 3KTYA 4J3CA 3AIAA 4YQNA 4YVJA 1V6ZA 4XBOA 2YY8A 5FAIA 3GYQA 3N4JA 3QUVA 4X3MA 4YQ9A 4YQ4A 2V3JA 4YPWA 4YQRA 4CNDA 2EGVA 4E8BA 4CNGA 4H3YA 4YQCA 3BBDA 3AI9X 4YQDA 1X7PA 2I6DA 4JAKA 1NS5A 1UAMA 3O7BA 4YVHA 3NK6A 4KGNA 1Z85A 3BBHA 3OIIA 4YQQA 5CO4A 1K3RA 2EGWA 4L69A 1V2XA 3BBEA 4YQOA 4YQBA 1X7OA 4PZKA 4YQIA 1O6DA 4YQPA 1NXZA 5GM8A 4YQ2A 3KY7A 3KW2A 3N4KA 4RG1A 3ILKA 1UALA 4MCBA 2V3KA 1OY5A 4YQ3A 4YVGA 4JWJA 1MXIA 2Z0YA 4YQSA 3NK7A 3L8UA 2CX8A 4H3ZA 3IEFA 4MCDA 4YPYA 4YQ8A 4YQGA 1VHKA 4IG6A 4YQ6A 4YQAA 4YQ7A 4YQLA 3OINA 3KNUA 3AXZA 3IC6A 4YPZA 4YVIA 1UAKA 4MCCA 4YQ1A 2QWVA 4JALA 2QMMA 4YVKA 1J85A 1UAJA 4KDZA 4JWGA 1P9PA 4YQTA 4CNFA 4X3LA 2O3AA 3E5YA 4YQ0A 4YPXA 1VH0A 3ONPA 5GMBA 4YQJA 4JWHA 1IPAA 4CNEA 1GZ0A 5GMCA 1ZJRA 3DCMX 4YQKA 1TO0A 4JWFA 4YQ5A 4FAKA
chains in the Genus database with same CATH topology
1VHYA 3OIJA 5D9FA 4FMWA 2HA8A 3KTYA 4J3CA 3AIAA 4YQNA 4YVJA 1V6ZA 4XBOA 2YY8A 5FAIA 3GYQA 3N4JA 3QUVA 4X3MA 4YQ9A 4YQ4A 2V3JA 4YPWA 4YQRA 4CNDA 2EGVA 4E8BA 4CNGA 4H3YA 4YQCA 3BBDA 3AI9X 4YQDA 1X7PA 2I6DA 4JAKA 1NS5A 1UAMA 3O7BA 4YVHA 3NK6A 4KGNA 1Z85A 3BBHA 3OIIA 4YQQA 5CO4A 1K3RA 2EGWA 4L69A 1V2XA 3BBEA 4YQOA 4YQBA 1X7OA 4PZKA 4YQIA 1O6DA 4YQPA 1NXZA 5GM8A 4YQ2A 3KY7A 3KW2A 3N4KA 4RG1A 3ILKA 1UALA 4MCBA 2V3KA 1OY5A 4YQ3A 4YVGA 4JWJA 1MXIA 2Z0YA 4YQSA 3NK7A 3L8UA 2CX8A 4H3ZA 3IEFA 4MCDA 4YPYA 4YQ8A 4YQGA 1VHKA 4IG6A 4YQ6A 4YQAA 4YQ7A 4YQLA 3OINA 3KNUA 3AXZA 3IC6A 4YPZA 4YVIA 1UAKA 4MCCA 4YQ1A 2QWVA 4JALA 2QMMA 4YVKA 1J85A 1UAJA 4KDZA 4JWGA 1P9PA 4YQTA 4CNFA 4X3LA 2O3AA 3E5YA 4YQ0A 4YPXA 1VH0A 3ONPA 5GMBA 4YQJA 4JWHA 1IPAA 4CNEA 1GZ0A 5GMCA 1ZJRA 3DCMX 4YQKA 1TO0A 4JWFA 4YQ5A 4FAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VHY A;  3OIJ A;  5D9F A;  2HA8 A;  3KTY A;  4J3C A;  3AIA A;  4YQN A;  4YVJ A;  1V6Z A;  4XBO A;  2YY8 A;  5FAI A;  3GYQ A;  3N4J A;  3QUV A;  4X3M A;  4YQ9 A;  4YQ4 A;  2V3J A;  4YPW A;  4YQR A;  4CND A;  2EGV A;  4E8B A;  4CNG A;  4H3Y A;  4YQC A;  3BBD A;  3AI9 X;  4YQD A;  1X7P A;  2I6D A;  4JAK A;  1NS5 A;  1UAM A;  3O7B A;  4YVH A;  3NK6 A;  4KGN A;  1Z85 A;  3BBH A;  3OII A;  4YQQ A;  5CO4 A;  1K3R A;  2EGW A;  4L69 A;  1V2X A;  3BBE A;  4YQO A;  4YQB A;  1X7O A;  4PZK A;  4YQI A;  1O6D A;  4YQP A;  1NXZ A;  5GM8 A;  4YQ2 A;  3KY7 A;  3KW2 A;  3N4K A;  4RG1 A;  3ILK A;  1UAL A;  4MCB A;  2V3K A;  1OY5 A;  4YQ3 A;  4YVG A;  1MXI A;  2Z0Y A;  4YQS A;  3NK7 A;  3L8U A;  2CX8 A;  4H3Z A;  3IEF A;  4MCD A;  4YPY A;  4YQ8 A;  4YQG A;  1VHK A;  4IG6 A;  4YQ6 A;  4YQA A;  4YQ7 A;  4YQL A;  3OIN A;  3KNU A;  3AXZ A;  3IC6 A;  4YPZ A;  4YVI A;  1UAK A;  4MCC A;  4YQ1 A;  2QWV A;  4JAL A;  2QMM A;  4YVK A;  1J85 A;  1UAJ A;  4KDZ A;  1P9P A;  4YQT A;  4CNF A;  4X3L A;  2O3A A;  3E5Y A;  4YQ0 A;  4YPX A;  1VH0 A;  3ONP A;  5GMB A;  4YQJ A;  1IPA A;  4CNE A;  1GZ0 A;  5GMC A;  1ZJR A;  3DCM X;  4YQK A;  1TO0 A;  4YQ5 A;  4FAK A; 
#chains in the Genus database with same CATH topology
 1VHY A;  3OIJ A;  5D9F A;  4FMW A;  2HA8 A;  3KTY A;  4J3C A;  3AIA A;  4YQN A;  4YVJ A;  1V6Z A;  4XBO A;  2YY8 A;  5FAI A;  3GYQ A;  3N4J A;  3QUV A;  4X3M A;  4YQ9 A;  4YQ4 A;  2V3J A;  4YPW A;  4YQR A;  4CND A;  2EGV A;  4E8B A;  4CNG A;  4H3Y A;  4YQC A;  3BBD A;  3AI9 X;  4YQD A;  1X7P A;  2I6D A;  4JAK A;  1NS5 A;  1UAM A;  3O7B A;  4YVH A;  3NK6 A;  4KGN A;  1Z85 A;  3BBH A;  3OII A;  4YQQ A;  5CO4 A;  1K3R A;  2EGW A;  4L69 A;  1V2X A;  3BBE A;  4YQO A;  4YQB A;  1X7O A;  4PZK A;  4YQI A;  1O6D A;  4YQP A;  1NXZ A;  5GM8 A;  4YQ2 A;  3KY7 A;  3KW2 A;  3N4K A;  4RG1 A;  3ILK A;  1UAL A;  4MCB A;  2V3K A;  1OY5 A;  4YQ3 A;  4YVG A;  4JWJ A;  1MXI A;  2Z0Y A;  4YQS A;  3NK7 A;  3L8U A;  2CX8 A;  4H3Z A;  3IEF A;  4MCD A;  4YPY A;  4YQ8 A;  4YQG A;  1VHK A;  4IG6 A;  4YQ6 A;  4YQA A;  4YQ7 A;  4YQL A;  3OIN A;  3KNU A;  3AXZ A;  3IC6 A;  4YPZ A;  4YVI A;  1UAK A;  4MCC A;  4YQ1 A;  2QWV A;  4JAL A;  2QMM A;  4YVK A;  1J85 A;  1UAJ A;  4KDZ A;  4JWG A;  1P9P A;  4YQT A;  4CNF A;  4X3L A;  2O3A A;  3E5Y A;  4YQ0 A;  4YPX A;  1VH0 A;  3ONP A;  5GMB A;  4YQJ A;  4JWH A;  1IPA A;  4CNE A;  1GZ0 A;  5GMC A;  1ZJR A;  3DCM X;  4YQK A;  1TO0 A;  4JWF A;  4YQ5 A;  4FAK A; 
#chains in the Genus database with same CATH homology
 1VHY A;  3OIJ A;  5D9F A;  4FMW A;  2HA8 A;  3KTY A;  4J3C A;  3AIA A;  4YQN A;  4YVJ A;  1V6Z A;  4XBO A;  2YY8 A;  5FAI A;  3GYQ A;  3N4J A;  3QUV A;  4X3M A;  4YQ9 A;  4YQ4 A;  2V3J A;  4YPW A;  4YQR A;  4CND A;  2EGV A;  4E8B A;  4CNG A;  4H3Y A;  4YQC A;  3BBD A;  3AI9 X;  4YQD A;  1X7P A;  2I6D A;  4JAK A;  1NS5 A;  1UAM A;  3O7B A;  4YVH A;  3NK6 A;  4KGN A;  1Z85 A;  3BBH A;  3OII A;  4YQQ A;  5CO4 A;  1K3R A;  2EGW A;  4L69 A;  1V2X A;  3BBE A;  4YQO A;  4YQB A;  1X7O A;  4PZK A;  4YQI A;  1O6D A;  4YQP A;  1NXZ A;  5GM8 A;  4YQ2 A;  3KY7 A;  3KW2 A;  3N4K A;  4RG1 A;  3ILK A;  1UAL A;  4MCB A;  2V3K A;  1OY5 A;  4YQ3 A;  4YVG A;  4JWJ A;  1MXI A;  2Z0Y A;  4YQS A;  3NK7 A;  3L8U A;  2CX8 A;  4H3Z A;  3IEF A;  4MCD A;  4YPY A;  4YQ8 A;  4YQG A;  1VHK A;  4IG6 A;  4YQ6 A;  4YQA A;  4YQ7 A;  4YQL A;  3OIN A;  3KNU A;  3AXZ A;  3IC6 A;  4YPZ A;  4YVI A;  1UAK A;  4MCC A;  4YQ1 A;  2QWV A;  4JAL A;  2QMM A;  4YVK A;  1J85 A;  1UAJ A;  4KDZ A;  4JWG A;  1P9P A;  4YQT A;  4CNF A;  4X3L A;  2O3A A;  3E5Y A;  4YQ0 A;  4YPX A;  1VH0 A;  3ONP A;  5GMB A;  4YQJ A;  4JWH A;  1IPA A;  4CNE A;  1GZ0 A;  5GMC A;  1ZJR A;  3DCM X;  4YQK A;  1TO0 A;  4JWF A;  4YQ5 A;  4FAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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