4FAKA

Crystal structure of orfx in complex with s-adenosylmethionine
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
Knots found
sequence length
163
structure length
163
Chain Sequence
AAEFMKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site.
pubmed doi rcsb
molecule tags Transferase, ribosomal protein
source organism Staphylococcus aureus
molecule keywords Ribosomal RNA large subunit methyltransferase H
total genus 53
structure length 163
sequence length 163
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.177: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
pdb deposition date 2012-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02590 SPOUT_MTase Predicted SPOUT methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4fakA00
4YPXA 2Z0YA 4YQCA 3DCMX 3IEFA 1P9PA 3AI9X 4YPYA 1IPAA 4IG6A 4YQ4A 3KY7A 1O6DA 3AIAA 1UALA 4YQ9A 3IC6A 4MCBA 4YPZA 1J85A 1OY5A 4YQKA 1NS5A 4YVJA 4YQ2A 1V2XA 3KTYA 4YQNA 3ILKA 4YPWA 3BBHA 2V3KA 3NK6A 4KDZA 3AXZA 4YQJA 5GMCA 4YQ5A 4YVIA 1UAKA 4YQRA 4XBOA 4E8BA 4YQ3A 4YQ7A 1Z85A 3O7BA 4CNGA 1V6ZA 4YQ6A 4YVGA 3ONPA 5FAIA 1ZJRA 4MCDA 1GZ0A 4X3LA 2EGVA 4YQGA 4H3YA 3NK7A 5D9FA 4YQ8A 2CX8A 4YQ1A 3OIJA 3BBDA 1UAJA 3N4JA 4YVHA 5GMBA 3OIIA 1NXZA 4PZKA 3L8UA 4YQOA 4YQ0A 1VHKA 2QMMA 1X7PA 3OINA 3QUVA 4YQAA 4JAKA 4YQIA 4YQBA 1VHYA 4YQLA 4FAKA 1UAMA 4X3MA 1VH0A 4CNEA 3BBEA 2O3AA 2YY8A 4YQPA 3GYQA 4H3ZA 1MXIA 1TO0A 2EGWA 2V3JA 4CNFA 4CNDA 3KNUA 2HA8A 3N4KA 4MCCA 1K3RA 5CO4A 4YQQA 4RG1A 3KW2A 4J3CA 1X7OA 4YVKA 4L69A 3E5YA 4YQSA 4JALA 2I6DA 4KGNA 4YQTA 4YQDA 5GM8A 2QWVA
chains in the Genus database with same CATH superfamily
4YPXA 2Z0YA 4YQCA 3DCMX 3IEFA 1P9PA 3AI9X 4YPYA 1IPAA 4IG6A 4YQ4A 3KY7A 1O6DA 3AIAA 1UALA 4YQ9A 3IC6A 4MCBA 4YPZA 1J85A 1OY5A 4YQKA 1NS5A 4YVJA 4YQ2A 1V2XA 3KTYA 4YQNA 3ILKA 4YPWA 3BBHA 4JWFA 2V3KA 3NK6A 4KDZA 3AXZA 4YQJA 5GMCA 4YQ5A 4YVIA 1UAKA 4YQRA 4XBOA 4E8BA 4YQ3A 4YQ7A 1Z85A 3O7BA 4CNGA 1V6ZA 4YQ6A 4YVGA 3ONPA 5FAIA 1ZJRA 4MCDA 1GZ0A 4X3LA 2EGVA 4YQGA 4H3YA 4JWGA 3NK7A 5D9FA 4YQ8A 2CX8A 4YQ1A 3OIJA 3BBDA 1UAJA 3N4JA 4YVHA 5GMBA 3OIIA 1NXZA 4PZKA 3L8UA 4YQOA 4YQ0A 4JWJA 1VHKA 2QMMA 1X7PA 3OINA 3QUVA 4FMWA 4YQAA 4JAKA 4YQIA 4YQBA 1VHYA 4YQLA 4FAKA 1UAMA 4X3MA 1VH0A 4CNEA 3BBEA 2O3AA 2YY8A 4YQPA 4JWHA 3GYQA 4H3ZA 1MXIA 1TO0A 2EGWA 2V3JA 4CNFA 4CNDA 3KNUA 2HA8A 3N4KA 4MCCA 1K3RA 5CO4A 4YQQA 4RG1A 3KW2A 4J3CA 1X7OA 4YVKA 4L69A 3E5YA 4YQSA 4JALA 2I6DA 4KGNA 4YQTA 4YQDA 5GM8A 2QWVA
chains in the Genus database with same CATH topology
4YPXA 2Z0YA 4YQCA 3DCMX 3IEFA 1P9PA 3AI9X 4YPYA 1IPAA 4IG6A 4YQ4A 3KY7A 1O6DA 3AIAA 1UALA 4YQ9A 3IC6A 4MCBA 4YPZA 1J85A 1OY5A 4YQKA 1NS5A 4YVJA 4YQ2A 1V2XA 3KTYA 4YQNA 3ILKA 4YPWA 3BBHA 4JWFA 2V3KA 3NK6A 4KDZA 3AXZA 4YQJA 5GMCA 4YQ5A 4YVIA 1UAKA 4YQRA 4XBOA 4E8BA 4YQ3A 4YQ7A 1Z85A 3O7BA 4CNGA 1V6ZA 4YQ6A 4YVGA 3ONPA 5FAIA 1ZJRA 4MCDA 1GZ0A 4X3LA 2EGVA 4YQGA 4H3YA 4JWGA 3NK7A 5D9FA 4YQ8A 2CX8A 4YQ1A 3OIJA 3BBDA 1UAJA 3N4JA 4YVHA 5GMBA 3OIIA 1NXZA 4PZKA 3L8UA 4YQOA 4YQ0A 4JWJA 1VHKA 2QMMA 1X7PA 3OINA 3QUVA 4FMWA 4YQAA 4JAKA 4YQIA 4YQBA 1VHYA 4YQLA 4FAKA 1UAMA 4X3MA 1VH0A 4CNEA 3BBEA 2O3AA 2YY8A 4YQPA 4JWHA 3GYQA 4H3ZA 1MXIA 1TO0A 2EGWA 2V3JA 4CNFA 4CNDA 3KNUA 2HA8A 3N4KA 4MCCA 1K3RA 5CO4A 4YQQA 4RG1A 3KW2A 4J3CA 1X7OA 4YVKA 4L69A 3E5YA 4YQSA 4JALA 2I6DA 4KGNA 4YQTA 4YQDA 5GM8A 2QWVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPX A;  2Z0Y A;  4YQC A;  3DCM X;  3IEF A;  1P9P A;  3AI9 X;  4YPY A;  1IPA A;  4IG6 A;  4YQ4 A;  3KY7 A;  1O6D A;  3AIA A;  1UAL A;  4YQ9 A;  3IC6 A;  4MCB A;  4YPZ A;  1J85 A;  1OY5 A;  4YQK A;  1NS5 A;  4YVJ A;  4YQ2 A;  1V2X A;  3KTY A;  4YQN A;  3ILK A;  4YPW A;  3BBH A;  2V3K A;  3NK6 A;  4KDZ A;  3AXZ A;  4YQJ A;  5GMC A;  4YQ5 A;  4YVI A;  1UAK A;  4YQR A;  4XBO A;  4E8B A;  4YQ3 A;  4YQ7 A;  1Z85 A;  3O7B A;  4CNG A;  1V6Z A;  4YQ6 A;  4YVG A;  3ONP A;  5FAI A;  1ZJR A;  4MCD A;  1GZ0 A;  4X3L A;  2EGV A;  4YQG A;  4H3Y A;  3NK7 A;  5D9F A;  4YQ8 A;  2CX8 A;  4YQ1 A;  3OIJ A;  3BBD A;  1UAJ A;  3N4J A;  4YVH A;  5GMB A;  3OII A;  1NXZ A;  4PZK A;  3L8U A;  4YQO A;  4YQ0 A;  1VHK A;  2QMM A;  1X7P A;  3OIN A;  3QUV A;  4YQA A;  4JAK A;  4YQI A;  4YQB A;  1VHY A;  4YQL A;  4FAK A;  1UAM A;  4X3M A;  1VH0 A;  4CNE A;  3BBE A;  2O3A A;  2YY8 A;  4YQP A;  3GYQ A;  4H3Z A;  1MXI A;  1TO0 A;  2EGW A;  2V3J A;  4CNF A;  4CND A;  3KNU A;  2HA8 A;  3N4K A;  4MCC A;  1K3R A;  5CO4 A;  4YQQ A;  4RG1 A;  3KW2 A;  4J3C A;  1X7O A;  4YVK A;  4L69 A;  3E5Y A;  4YQS A;  4JAL A;  2I6D A;  4KGN A;  4YQT A;  4YQD A;  5GM8 A;  2QWV A; 
#chains in the Genus database with same CATH topology
 4YPX A;  2Z0Y A;  4YQC A;  3DCM X;  3IEF A;  1P9P A;  3AI9 X;  4YPY A;  1IPA A;  4IG6 A;  4YQ4 A;  3KY7 A;  1O6D A;  3AIA A;  1UAL A;  4YQ9 A;  3IC6 A;  4MCB A;  4YPZ A;  1J85 A;  1OY5 A;  4YQK A;  1NS5 A;  4YVJ A;  4YQ2 A;  1V2X A;  3KTY A;  4YQN A;  3ILK A;  4YPW A;  3BBH A;  4JWF A;  2V3K A;  3NK6 A;  4KDZ A;  3AXZ A;  4YQJ A;  5GMC A;  4YQ5 A;  4YVI A;  1UAK A;  4YQR A;  4XBO A;  4E8B A;  4YQ3 A;  4YQ7 A;  1Z85 A;  3O7B A;  4CNG A;  1V6Z A;  4YQ6 A;  4YVG A;  3ONP A;  5FAI A;  1ZJR A;  4MCD A;  1GZ0 A;  4X3L A;  2EGV A;  4YQG A;  4H3Y A;  4JWG A;  3NK7 A;  5D9F A;  4YQ8 A;  2CX8 A;  4YQ1 A;  3OIJ A;  3BBD A;  1UAJ A;  3N4J A;  4YVH A;  5GMB A;  3OII A;  1NXZ A;  4PZK A;  3L8U A;  4YQO A;  4YQ0 A;  4JWJ A;  1VHK A;  2QMM A;  1X7P A;  3OIN A;  3QUV A;  4FMW A;  4YQA A;  4JAK A;  4YQI A;  4YQB A;  1VHY A;  4YQL A;  4FAK A;  1UAM A;  4X3M A;  1VH0 A;  4CNE A;  3BBE A;  2O3A A;  2YY8 A;  4YQP A;  4JWH A;  3GYQ A;  4H3Z A;  1MXI A;  1TO0 A;  2EGW A;  2V3J A;  4CNF A;  4CND A;  3KNU A;  2HA8 A;  3N4K A;  4MCC A;  1K3R A;  5CO4 A;  4YQQ A;  4RG1 A;  3KW2 A;  4J3C A;  1X7O A;  4YVK A;  4L69 A;  3E5Y A;  4YQS A;  4JAL A;  2I6D A;  4KGN A;  4YQT A;  4YQD A;  5GM8 A;  2QWV A; 
#chains in the Genus database with same CATH homology
 4YPX A;  2Z0Y A;  4YQC A;  3DCM X;  3IEF A;  1P9P A;  3AI9 X;  4YPY A;  1IPA A;  4IG6 A;  4YQ4 A;  3KY7 A;  1O6D A;  3AIA A;  1UAL A;  4YQ9 A;  3IC6 A;  4MCB A;  4YPZ A;  1J85 A;  1OY5 A;  4YQK A;  1NS5 A;  4YVJ A;  4YQ2 A;  1V2X A;  3KTY A;  4YQN A;  3ILK A;  4YPW A;  3BBH A;  4JWF A;  2V3K A;  3NK6 A;  4KDZ A;  3AXZ A;  4YQJ A;  5GMC A;  4YQ5 A;  4YVI A;  1UAK A;  4YQR A;  4XBO A;  4E8B A;  4YQ3 A;  4YQ7 A;  1Z85 A;  3O7B A;  4CNG A;  1V6Z A;  4YQ6 A;  4YVG A;  3ONP A;  5FAI A;  1ZJR A;  4MCD A;  1GZ0 A;  4X3L A;  2EGV A;  4YQG A;  4H3Y A;  4JWG A;  3NK7 A;  5D9F A;  4YQ8 A;  2CX8 A;  4YQ1 A;  3OIJ A;  3BBD A;  1UAJ A;  3N4J A;  4YVH A;  5GMB A;  3OII A;  1NXZ A;  4PZK A;  3L8U A;  4YQO A;  4YQ0 A;  4JWJ A;  1VHK A;  2QMM A;  1X7P A;  3OIN A;  3QUV A;  4FMW A;  4YQA A;  4JAK A;  4YQI A;  4YQB A;  1VHY A;  4YQL A;  4FAK A;  1UAM A;  4X3M A;  1VH0 A;  4CNE A;  3BBE A;  2O3A A;  2YY8 A;  4YQP A;  4JWH A;  3GYQ A;  4H3Z A;  1MXI A;  1TO0 A;  2EGW A;  2V3J A;  4CNF A;  4CND A;  3KNU A;  2HA8 A;  3N4K A;  4MCC A;  1K3R A;  5CO4 A;  4YQQ A;  4RG1 A;  3KW2 A;  4J3C A;  1X7O A;  4YVK A;  4L69 A;  3E5Y A;  4YQS A;  4JAL A;  2I6D A;  4KGN A;  4YQT A;  4YQD A;  5GM8 A;  2QWV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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