4FMWA

Crystal structure of methyltransferase domain of human rna (guanine-9-) methyltransferase domain containing protein 2
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
Knots found
sequence length
182
structure length
178
Chain Sequence
RDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVRKVLAVNHVFEIILEYLETRDWQEAFFTILPQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords RNA (guanine-9-)-methyltransferase domain-containing protein
total genus 58
structure length 178
sequence length 182
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.221: tRNA (guanine(9)-N(1))-methyltransferase.
pdb deposition date 2012-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.30 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4fmwA00
4JWHA 4JWGA 4FMWA 4JWJA 4JWFA
chains in the Genus database with same CATH superfamily
4KGNA 3IC6A 3KW2A 4RG1A 3N4KA 3AXZA 4YVKA 3ILKA 4JAKA 4YVGA 1TO0A 1VHYA 3IEFA 4YQJA 4XBOA 2V3KA 4YQ6A 4YPZA 4JALA 2Z0YA 4YQNA 2I6DA 1P9PA 2QMMA 4YQ5A 1ZJRA 3N4JA 1OY5A 4H3YA 4YQSA 4YQAA 3DCMX 4H3ZA 4YQCA 4L69A 4PZKA 4E8BA 1X7OA 4FAKA 4YQTA 4YQ1A 4YVHA 3ONPA 4YQPA 5FAIA 4YQ7A 2EGWA 4YQDA 5GM8A 3BBEA 1NXZA 1K3RA 4YQKA 4YQIA 1V2XA 3KTYA 3AI9X 1UALA 4YQGA 1VHKA 4X3MA 1IPAA 1VH0A 5D9FA 4FMWA 1X7PA 1NS5A 4YQ2A 4YQRA 1UAJA 3OIIA 4YPWA 4CNGA 3BBDA 1O6DA 4YQOA 1GZ0A 4IG6A 4YQ3A 5GMBA 4J3CA 3AIAA 4YQ0A 4YQQA 4YVJA 4YQ4A 4YQ8A 4YQ9A 4YPXA 4JWGA 4MCCA 1MXIA 4YQBA 2V3JA 4JWFA 4JWHA 1Z85A 2O3AA 3BBHA 2QWVA 3E5YA 3NK7A 4YQLA 3KNUA 3O7BA 4CNFA 3L8UA 1V6ZA 4CNEA 3KY7A 4MCBA 3QUVA 4KDZA 5CO4A 2YY8A 5GMCA 3OINA 4MCDA 4X3LA 4YVIA 3OIJA 2EGVA 1J85A 1UAMA 4JWJA 2HA8A 3GYQA 3NK6A 1UAKA 4CNDA 4YPYA 2CX8A
chains in the Genus database with same CATH topology
4KGNA 3IC6A 3KW2A 4RG1A 3N4KA 3AXZA 4YVKA 3ILKA 4JAKA 4YVGA 1TO0A 1VHYA 3IEFA 4YQJA 4XBOA 2V3KA 4YQ6A 4YPZA 4JALA 2Z0YA 4YQNA 2I6DA 1P9PA 2QMMA 4YQ5A 1ZJRA 3N4JA 1OY5A 4H3YA 4YQSA 4YQAA 3DCMX 4H3ZA 4YQCA 4L69A 4PZKA 4E8BA 1X7OA 4FAKA 4YQTA 4YQ1A 4YVHA 3ONPA 4YQPA 5FAIA 4YQ7A 2EGWA 4YQDA 5GM8A 3BBEA 1NXZA 1K3RA 4YQKA 4YQIA 1V2XA 3KTYA 3AI9X 1UALA 4YQGA 1VHKA 4X3MA 1IPAA 1VH0A 5D9FA 4FMWA 1X7PA 1NS5A 4YQ2A 4YQRA 1UAJA 3OIIA 4YPWA 4CNGA 3BBDA 1O6DA 4YQOA 1GZ0A 4IG6A 4YQ3A 5GMBA 4J3CA 3AIAA 4YQ0A 4YQQA 4YVJA 4YQ4A 4YQ8A 4YQ9A 4YPXA 4JWGA 4MCCA 1MXIA 4YQBA 2V3JA 4JWFA 4JWHA 1Z85A 2O3AA 3BBHA 2QWVA 3E5YA 3NK7A 4YQLA 3KNUA 3O7BA 4CNFA 3L8UA 1V6ZA 4CNEA 3KY7A 4MCBA 3QUVA 4KDZA 5CO4A 2YY8A 5GMCA 3OINA 4MCDA 4X3LA 4YVIA 3OIJA 2EGVA 1J85A 1UAMA 4JWJA 2HA8A 3GYQA 3NK6A 1UAKA 4CNDA 4YPYA 2CX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JWH A;  4JWG A;  4FMW A;  4JWJ A;  4JWF A; 
#chains in the Genus database with same CATH topology
 4KGN A;  3IC6 A;  3KW2 A;  4RG1 A;  3N4K A;  3AXZ A;  4YVK A;  3ILK A;  4JAK A;  4YVG A;  1TO0 A;  1VHY A;  3IEF A;  4YQJ A;  4XBO A;  2V3K A;  4YQ6 A;  4YPZ A;  4JAL A;  2Z0Y A;  4YQN A;  2I6D A;  1P9P A;  2QMM A;  4YQ5 A;  1ZJR A;  3N4J A;  1OY5 A;  4H3Y A;  4YQS A;  4YQA A;  3DCM X;  4H3Z A;  4YQC A;  4L69 A;  4PZK A;  4E8B A;  1X7O A;  4FAK A;  4YQT A;  4YQ1 A;  4YVH A;  3ONP A;  4YQP A;  5FAI A;  4YQ7 A;  2EGW A;  4YQD A;  5GM8 A;  3BBE A;  1NXZ A;  1K3R A;  4YQK A;  4YQI A;  1V2X A;  3KTY A;  3AI9 X;  1UAL A;  4YQG A;  1VHK A;  4X3M A;  1IPA A;  1VH0 A;  5D9F A;  4FMW A;  1X7P A;  1NS5 A;  4YQ2 A;  4YQR A;  1UAJ A;  3OII A;  4YPW A;  4CNG A;  3BBD A;  1O6D A;  4YQO A;  1GZ0 A;  4IG6 A;  4YQ3 A;  5GMB A;  4J3C A;  3AIA A;  4YQ0 A;  4YQQ A;  4YVJ A;  4YQ4 A;  4YQ8 A;  4YQ9 A;  4YPX A;  4JWG A;  4MCC A;  1MXI A;  4YQB A;  2V3J A;  4JWF A;  4JWH A;  1Z85 A;  2O3A A;  3BBH A;  2QWV A;  3E5Y A;  3NK7 A;  4YQL A;  3KNU A;  3O7B A;  4CNF A;  3L8U A;  1V6Z A;  4CNE A;  3KY7 A;  4MCB A;  3QUV A;  4KDZ A;  5CO4 A;  2YY8 A;  5GMC A;  3OIN A;  4MCD A;  4X3L A;  4YVI A;  3OIJ A;  2EGV A;  1J85 A;  1UAM A;  4JWJ A;  2HA8 A;  3GYQ A;  3NK6 A;  1UAK A;  4CND A;  4YPY A;  2CX8 A; 
#chains in the Genus database with same CATH homology
 4KGN A;  3IC6 A;  3KW2 A;  4RG1 A;  3N4K A;  3AXZ A;  4YVK A;  3ILK A;  4JAK A;  4YVG A;  1TO0 A;  1VHY A;  3IEF A;  4YQJ A;  4XBO A;  2V3K A;  4YQ6 A;  4YPZ A;  4JAL A;  2Z0Y A;  4YQN A;  2I6D A;  1P9P A;  2QMM A;  4YQ5 A;  1ZJR A;  3N4J A;  1OY5 A;  4H3Y A;  4YQS A;  4YQA A;  3DCM X;  4H3Z A;  4YQC A;  4L69 A;  4PZK A;  4E8B A;  1X7O A;  4FAK A;  4YQT A;  4YQ1 A;  4YVH A;  3ONP A;  4YQP A;  5FAI A;  4YQ7 A;  2EGW A;  4YQD A;  5GM8 A;  3BBE A;  1NXZ A;  1K3R A;  4YQK A;  4YQI A;  1V2X A;  3KTY A;  3AI9 X;  1UAL A;  4YQG A;  1VHK A;  4X3M A;  1IPA A;  1VH0 A;  5D9F A;  4FMW A;  1X7P A;  1NS5 A;  4YQ2 A;  4YQR A;  1UAJ A;  3OII A;  4YPW A;  4CNG A;  3BBD A;  1O6D A;  4YQO A;  1GZ0 A;  4IG6 A;  4YQ3 A;  5GMB A;  4J3C A;  3AIA A;  4YQ0 A;  4YQQ A;  4YVJ A;  4YQ4 A;  4YQ8 A;  4YQ9 A;  4YPX A;  4JWG A;  4MCC A;  1MXI A;  4YQB A;  2V3J A;  4JWF A;  4JWH A;  1Z85 A;  2O3A A;  3BBH A;  2QWV A;  3E5Y A;  3NK7 A;  4YQL A;  3KNU A;  3O7B A;  4CNF A;  3L8U A;  1V6Z A;  4CNE A;  3KY7 A;  4MCB A;  3QUV A;  4KDZ A;  5CO4 A;  2YY8 A;  5GMC A;  3OIN A;  4MCD A;  4X3L A;  4YVI A;  3OIJ A;  2EGV A;  1J85 A;  1UAM A;  4JWJ A;  2HA8 A;  3GYQ A;  3NK6 A;  1UAK A;  4CND A;  4YPY A;  2CX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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