1DDFA

Fas death domain, nmr, minimized average structure
Total Genus 24
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
127
structure length
127
Chain Sequence
METVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLVLEHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain.
pubmed doi rcsb
molecule tags Death domain
source organism Homo sapiens
molecule keywords FAS
total genus 24
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 1996-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1ddfA00
4QOBA 2O71A 4O6XA 1YGOA 4JQWA 1Z6TA 2B1WA 4IZ5E 2N83A 1C15A 2MN4A 4NQKA 2N80A 4E9MA 2HM2Q 4FH0A 4ZBWA 2A5YB 4O9LA 3QF2A 2DBDA 2D96A 2KN6A 3CRDA 1A1ZA 3YGSP 1PN5A 3MOPK 1UCPA 4D8OA 2VGQA 2MB9A 1CY5A 3YGSC 3CL3A 2N00A 4DWNA 2IB1A 3KATA 4UZ0A 4EWIA 3MOPA 2N97A 2YU0A 3T6PA 2DBHA 3EZQA 4M9XA 1D2ZB 4LWDA 3J63A 1WXPA 2MS8A 2LS7A 4F42A 1N3KA 2BBRA 2DBFA 4I16A 4A2QA 4RHWA 1FADA 4N1KA 4N1JA 3LQQA 1E41A 2YVIA 1NGRA 1WMGA 4IZAB 2OF5A 3J6JA 1D2ZA 2NZ7A 2DO9A 4O9FA 2L6AA 2N1FA 1ICHA 2KM6A 2YGSA 4M9ZA 2BBZA 4A2WA 1DGNA 1CWWA 3LQRA 2A9IA 4M9SA 2OF5H 2N7ZA 2DBGA 4N1LA 2G7RA 4IZ7B 1E3YA 4RHWE 4F44A 2GF5A 2LWEA 2NSNA 4P4HI 2L9MA 2MS7A 1DDFA 1WH4A 4O7QA 3MOPG 2MPCA 1A1WA 2M5VA 4P4HA 2F1SA 2LWDA 2YQFA 2NAQA 2P1HA 4JUPA 3EZQB
chains in the Genus database with same CATH superfamily
4QOBA 2O71A 4O6XA 1YGOA 4JQWA 1Z6TA 2B1WA 4IZ5E 2N83A 1C15A 2MN4A 2MJMA 4NQKA 2N80A 4E9MA 2HM2Q 4FH0A 4ZBWA 2A5YB 4O9LA 2DBDA 2D96A 3QF2A 2KN6A 3CRDA 1A1ZA 3YGSP 1PN5A 3MOPK 1UCPA 4D8OA 2VGQA 2MB9A 1CY5A 3YGSC 3CL3A 2N00A 4DWNA 2IB1A 3KATA 4UZ0A 4EWIA 3MOPA 2N97A 2YU0A 3T6PA 2DBHA 3EZQA 4M9XA 1D2ZB 4LWDA 3J63A 1WXPA 2MS8A 2LS7A 4F42A 1N3KA 2BBRA 2DBFA 4I16A 4A2QA 4RHWA 1FADA 4N1KA 4N1JA 3LQQA 1E41A 2YVIA 1NGRA 1WMGA 4IZAB 2OF5A 3J6JA 1D2ZA 2NZ7A 2DO9A 4O9FA 2L6AA 2N1FA 1ICHA 2KM6A 2YGSA 4M9ZA 2BBZA 4A2WA 1DGNA 1CWWA 3LQRA 2A9IA 4M9SA 2OF5H 2N7ZA 2DBGA 4N1LA 2G7RA 4IZ7B 1E3YA 4RHWE 4F44A 2GF5A 2LWEA 2NSNA 4P4HI 2L9MA 2MS7A 1DDFA 1WH4A 4O7QA 3MOPG 2MPCA 1A1WA 2M5VA 4P4HA 2F1SA 2LWDA 2YQFA 2NAQA 2P1HA 4JUPA 2XV9A 3EZQB
chains in the Genus database with same CATH topology
4QOBA 2O71A 4O6XA 1YGOA 4JQWA 1Z6TA 2B1WA 4IZ5E 2N83A 1C15A 2MN4A 2MJMA 4NQKA 2N80A 4E9MA 2HM2Q 4FH0A 4ZBWA 2A5YB 4O9LA 2DBDA 2D96A 3QF2A 2KN6A 3CRDA 1A1ZA 3YGSP 1PN5A 3MOPK 1UCPA 4D8OA 2VGQA 2MB9A 1CY5A 3YGSC 3CL3A 2N00A 4DWNA 2IB1A 3KATA 4UZ0A 4EWIA 3MOPA 2N97A 2YU0A 3T6PA 2DBHA 3EZQA 4M9XA 1D2ZB 4LWDA 3J63A 1WXPA 2MS8A 2LS7A 4F42A 1N3KA 2BBRA 2DBFA 4I16A 4A2QA 4RHWA 1FADA 4N1KA 4N1JA 3LQQA 1E41A 2YVIA 1NGRA 1WMGA 4IZAB 2OF5A 3J6JA 1D2ZA 2NZ7A 2DO9A 4O9FA 2L6AA 2N1FA 1ICHA 2KM6A 2YGSA 4M9ZA 2BBZA 4A2WA 1DGNA 1CWWA 3LQRA 2A9IA 4M9SA 2OF5H 2N7ZA 2DBGA 4N1LA 2G7RA 4IZ7B 1E3YA 4RHWE 4F44A 2GF5A 2LWEA 2NSNA 4P4HI 2L9MA 2MS7A 1DDFA 1WH4A 4O7QA 3MOPG 2MPCA 1A1WA 2M5VA 4P4HA 2F1SA 2LWDA 2YQFA 2NAQA 2P1HA 4JUPA 2XV9A 3EZQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QOB A;  2O71 A;  4O6X A;  1YGO A;  4JQW A;  1Z6T A;  2B1W A;  4IZ5 E;  2N83 A;  1C15 A;  2MN4 A;  4NQK A;  2N80 A;  4E9M A;  2HM2 Q;  4FH0 A;  4ZBW A;  2A5Y B;  4O9L A;  3QF2 A;  2DBD A;  2D96 A;  2KN6 A;  3CRD A;  1A1Z A;  3YGS P;  1PN5 A;  3MOP K;  1UCP A;  4D8O A;  2VGQ A;  2MB9 A;  1CY5 A;  3YGS C;  3CL3 A;  2N00 A;  4DWN A;  2IB1 A;  3KAT A;  4UZ0 A;  4EWI A;  3MOP A;  2N97 A;  2YU0 A;  3T6P A;  2DBH A;  3EZQ A;  4M9X A;  1D2Z B;  4LWD A;  3J63 A;  1WXP A;  2MS8 A;  2LS7 A;  4F42 A;  1N3K A;  2BBR A;  2DBF A;  4I16 A;  4A2Q A;  4RHW A;  1FAD A;  4N1K A;  4N1J A;  3LQQ A;  1E41 A;  2YVI A;  1NGR A;  1WMG A;  4IZA B;  2OF5 A;  3J6J A;  1D2Z A;  2NZ7 A;  2DO9 A;  4O9F A;  2L6A A;  2N1F A;  1ICH A;  2KM6 A;  2YGS A;  4M9Z A;  2BBZ A;  4A2W A;  1DGN A;  1CWW A;  3LQR A;  2A9I A;  4M9S A;  2OF5 H;  2N7Z A;  2DBG A;  4N1L A;  2G7R A;  4IZ7 B;  1E3Y A;  4RHW E;  4F44 A;  2GF5 A;  2LWE A;  2NSN A;  4P4H I;  2L9M A;  2MS7 A;  1DDF A;  1WH4 A;  4O7Q A;  3MOP G;  2MPC A;  1A1W A;  2M5V A;  4P4H A;  2F1S A;  2LWD A;  2YQF A;  2NAQ A;  2P1H A;  4JUP A;  3EZQ B; 
#chains in the Genus database with same CATH topology
 4QOB A;  2O71 A;  4O6X A;  1YGO A;  4JQW A;  1Z6T A;  2B1W A;  4IZ5 E;  2N83 A;  1C15 A;  2MN4 A;  2MJM A;  4NQK A;  2N80 A;  4E9M A;  2HM2 Q;  4FH0 A;  4ZBW A;  2A5Y B;  4O9L A;  2DBD A;  2D96 A;  3QF2 A;  2KN6 A;  3CRD A;  1A1Z A;  3YGS P;  1PN5 A;  3MOP K;  1UCP A;  4D8O A;  2VGQ A;  2MB9 A;  1CY5 A;  3YGS C;  3CL3 A;  2N00 A;  4DWN A;  2IB1 A;  3KAT A;  4UZ0 A;  4EWI A;  3MOP A;  2N97 A;  2YU0 A;  3T6P A;  2DBH A;  3EZQ A;  4M9X A;  1D2Z B;  4LWD A;  3J63 A;  1WXP A;  2MS8 A;  2LS7 A;  4F42 A;  1N3K A;  2BBR A;  2DBF A;  4I16 A;  4A2Q A;  4RHW A;  1FAD A;  4N1K A;  4N1J A;  3LQQ A;  1E41 A;  2YVI A;  1NGR A;  1WMG A;  4IZA B;  2OF5 A;  3J6J A;  1D2Z A;  2NZ7 A;  2DO9 A;  4O9F A;  2L6A A;  2N1F A;  1ICH A;  2KM6 A;  2YGS A;  4M9Z A;  2BBZ A;  4A2W A;  1DGN A;  1CWW A;  3LQR A;  2A9I A;  4M9S A;  2OF5 H;  2N7Z A;  2DBG A;  4N1L A;  2G7R A;  4IZ7 B;  1E3Y A;  4RHW E;  4F44 A;  2GF5 A;  2LWE A;  2NSN A;  4P4H I;  2L9M A;  2MS7 A;  1DDF A;  1WH4 A;  4O7Q A;  3MOP G;  2MPC A;  1A1W A;  2M5V A;  4P4H A;  2F1S A;  2LWD A;  2YQF A;  2NAQ A;  2P1H A;  4JUP A;  2XV9 A;  3EZQ B; 
#chains in the Genus database with same CATH homology
 4QOB A;  2O71 A;  4O6X A;  1YGO A;  4JQW A;  1Z6T A;  2B1W A;  4IZ5 E;  2N83 A;  1C15 A;  2MN4 A;  2MJM A;  4NQK A;  2N80 A;  4E9M A;  2HM2 Q;  4FH0 A;  4ZBW A;  2A5Y B;  4O9L A;  2DBD A;  2D96 A;  3QF2 A;  2KN6 A;  3CRD A;  1A1Z A;  3YGS P;  1PN5 A;  3MOP K;  1UCP A;  4D8O A;  2VGQ A;  2MB9 A;  1CY5 A;  3YGS C;  3CL3 A;  2N00 A;  4DWN A;  2IB1 A;  3KAT A;  4UZ0 A;  4EWI A;  3MOP A;  2N97 A;  2YU0 A;  3T6P A;  2DBH A;  3EZQ A;  4M9X A;  1D2Z B;  4LWD A;  3J63 A;  1WXP A;  2MS8 A;  2LS7 A;  4F42 A;  1N3K A;  2BBR A;  2DBF A;  4I16 A;  4A2Q A;  4RHW A;  1FAD A;  4N1K A;  4N1J A;  3LQQ A;  1E41 A;  2YVI A;  1NGR A;  1WMG A;  4IZA B;  2OF5 A;  3J6J A;  1D2Z A;  2NZ7 A;  2DO9 A;  4O9F A;  2L6A A;  2N1F A;  1ICH A;  2KM6 A;  2YGS A;  4M9Z A;  2BBZ A;  4A2W A;  1DGN A;  1CWW A;  3LQR A;  2A9I A;  4M9S A;  2OF5 H;  2N7Z A;  2DBG A;  4N1L A;  2G7R A;  4IZ7 B;  1E3Y A;  4RHW E;  4F44 A;  2GF5 A;  2LWE A;  2NSN A;  4P4H I;  2L9M A;  2MS7 A;  1DDF A;  1WH4 A;  4O7Q A;  3MOP G;  2MPC A;  1A1W A;  2M5V A;  4P4H A;  2F1S A;  2LWD A;  2YQF A;  2NAQ A;  2P1H A;  4JUP A;  2XV9 A;  3EZQ B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...