2F1SA

Crystal structure of a viral flip mc159
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
177
structure length
177
Chain Sequence
VPSLPFLRHLLEELDSHEDSLLLFLCHDAAPGCTTVTQALCSLSQQRKLTLAALVEMLYVLQRMDLLKSRFGLSKEGAEQLLGTSFLTRYRKLMVCVGEELDSSELRALRLFACNLNPSLSTALSESSRFVELVLALENVGLVSPSSVSVLADMLRTLRRLDLCQQLVEYEQQEQAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Viral FLIP: INSIGHTS INTO FLIP-MEDIATED INHIBITION OF DEATH RECEPTOR SIGNALING.
pubmed doi rcsb
molecule tags Apoptosis
source organism Molluscum contagiosum virus subtype 1
molecule keywords Viral CASP8 and FADD-like apoptosis regulator
total genus 71
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01335 DED Death effector domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2f1sA02
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2f1sA01
2HM2Q 3QF2A 3CRDA 2NAQA 1CWWA 2N97A 2A9IA 1N3KA 3T6PA 1E3YA 2LWEA 3J6JA 4F42A 4P4HI 4A2WA 4IZ5E 1ICHA 4D8OA 1DGNA 2OF5H 4I16A 1YGOA 2A5YB 2DBHA 4LWDA 4O9LA 3LQQA 1WH4A 2L9MA 4M9XA 4M9SA 2LS7A 2N7ZA 4FH0A 2YGSA 4N1LA 2YQFA 4EWIA 1WMGA 2L6AA 1CY5A 3EZQB 2YU0A 2MS7A 4N1KA 2GF5A 3J63A 2DO9A 2NSNA 1E41A 1NGRA 2B1WA 3MOPG 4ZBWA 2D96A 2VGQA 2O71A 2YVIA 1DDFA 2IB1A 3YGSP 3YGSC 3CL3A 3MOPK 4QOBA 2N83A 2DBGA 4E9MA 4DWNA 1C15A 1A1WA 2LWDA 2BBZA 4UZ0A 1A1ZA 1WXPA 2KN6A 3EZQA 2N1FA 3KATA 2DBDA 2BBRA 1D2ZB 2NZ7A 2MN4A 1UCPA 4O9FA 2MPCA 2N00A 4M9ZA 3LQRA 2N80A 4O6XA 2MB9A 2P1HA 2DBFA 2MS8A 2OF5A 4N1JA 4IZ7B 4IZAB 4A2QA 4JQWA 3MOPA 2G7RA 4RHWA 1FADA 4JUPA 4NQKA 1D2ZA 2F1SA 2M5VA 1Z6TA 4F44A 1PN5A 4RHWE 2KM6A 4P4HA 4O7QA
chains in the Genus database with same CATH superfamily
2HM2Q 3QF2A 3CRDA 2NAQA 1CWWA 2N97A 2A9IA 1N3KA 3T6PA 1E3YA 2LWEA 3J6JA 4F42A 4P4HI 4A2WA 4IZ5E 1ICHA 4D8OA 1DGNA 2OF5H 4I16A 2MJMA 1YGOA 2A5YB 2DBHA 4LWDA 4O9LA 3LQQA 1WH4A 2L9MA 4M9XA 4M9SA 2LS7A 2N7ZA 4FH0A 2YGSA 4N1LA 2YQFA 4EWIA 1WMGA 2L6AA 1CY5A 3EZQB 2YU0A 2MS7A 4N1KA 2GF5A 3J63A 2DO9A 2NSNA 1E41A 1NGRA 2B1WA 3MOPG 4ZBWA 2XV9A 2D96A 2VGQA 2O71A 2YVIA 1DDFA 2IB1A 3YGSP 3YGSC 3CL3A 3MOPK 4QOBA 2N83A 2DBGA 4E9MA 4DWNA 1C15A 1A1WA 2LWDA 2BBZA 4UZ0A 1A1ZA 1WXPA 2KN6A 3EZQA 2N1FA 3KATA 2DBDA 2BBRA 1D2ZB 2NZ7A 2MN4A 1UCPA 4O9FA 2MPCA 2N00A 4M9ZA 3LQRA 2N80A 4O6XA 2MB9A 2P1HA 2DBFA 2MS8A 2OF5A 4N1JA 4IZ7B 4IZAB 4A2QA 4JQWA 3MOPA 2G7RA 4RHWA 1FADA 4JUPA 4NQKA 1D2ZA 2F1SA 2M5VA 1Z6TA 4F44A 1PN5A 4RHWE 2KM6A 4P4HA 4O7QA
chains in the Genus database with same CATH topology
2HM2Q 3QF2A 3CRDA 2NAQA 1CWWA 2N97A 2A9IA 1N3KA 3T6PA 1E3YA 2LWEA 3J6JA 4F42A 4P4HI 4A2WA 4IZ5E 1ICHA 4D8OA 1DGNA 2OF5H 4I16A 2MJMA 1YGOA 2A5YB 2DBHA 4LWDA 4O9LA 3LQQA 1WH4A 2L9MA 4M9XA 4M9SA 2LS7A 2N7ZA 4FH0A 2YGSA 4N1LA 2YQFA 4EWIA 1WMGA 2L6AA 1CY5A 3EZQB 2YU0A 2MS7A 4N1KA 2GF5A 3J63A 2DO9A 2NSNA 1E41A 1NGRA 2B1WA 3MOPG 4ZBWA 2XV9A 2D96A 2VGQA 2O71A 2YVIA 1DDFA 2IB1A 3YGSP 3YGSC 3CL3A 3MOPK 4QOBA 2N83A 2DBGA 4E9MA 4DWNA 1C15A 1A1WA 2LWDA 2BBZA 4UZ0A 1A1ZA 1WXPA 2KN6A 3EZQA 2N1FA 3KATA 2DBDA 2BBRA 1D2ZB 2NZ7A 2MN4A 1UCPA 4O9FA 2MPCA 2N00A 4M9ZA 3LQRA 2N80A 4O6XA 2MB9A 2P1HA 2DBFA 2MS8A 2OF5A 4N1JA 4IZ7B 4IZAB 4A2QA 4JQWA 3MOPA 2G7RA 4RHWA 1FADA 4JUPA 4NQKA 1D2ZA 2F1SA 2M5VA 1Z6TA 4F44A 1PN5A 4RHWE 2KM6A 4P4HA 4O7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HM2 Q;  3QF2 A;  3CRD A;  2NAQ A;  1CWW A;  2N97 A;  2A9I A;  1N3K A;  3T6P A;  1E3Y A;  2LWE A;  3J6J A;  4F42 A;  4P4H I;  4A2W A;  4IZ5 E;  1ICH A;  4D8O A;  1DGN A;  2OF5 H;  4I16 A;  1YGO A;  2A5Y B;  2DBH A;  4LWD A;  4O9L A;  3LQQ A;  1WH4 A;  2L9M A;  4M9X A;  4M9S A;  2LS7 A;  2N7Z A;  4FH0 A;  2YGS A;  4N1L A;  2YQF A;  4EWI A;  1WMG A;  2L6A A;  1CY5 A;  3EZQ B;  2YU0 A;  2MS7 A;  4N1K A;  2GF5 A;  3J63 A;  2DO9 A;  2NSN A;  1E41 A;  1NGR A;  2B1W A;  3MOP G;  4ZBW A;  2D96 A;  2VGQ A;  2O71 A;  2YVI A;  1DDF A;  2IB1 A;  3YGS P;  3YGS C;  3CL3 A;  3MOP K;  4QOB A;  2N83 A;  2DBG A;  4E9M A;  4DWN A;  1C15 A;  1A1W A;  2LWD A;  2BBZ A;  4UZ0 A;  1A1Z A;  1WXP A;  2KN6 A;  3EZQ A;  2N1F A;  3KAT A;  2DBD A;  2BBR A;  1D2Z B;  2NZ7 A;  2MN4 A;  1UCP A;  4O9F A;  2MPC A;  2N00 A;  4M9Z A;  3LQR A;  2N80 A;  4O6X A;  2MB9 A;  2P1H A;  2DBF A;  2MS8 A;  2OF5 A;  4N1J A;  4IZ7 B;  4IZA B;  4A2Q A;  4JQW A;  3MOP A;  2G7R A;  4RHW A;  1FAD A;  4JUP A;  4NQK A;  1D2Z A;  2F1S A;  2M5V A;  1Z6T A;  4F44 A;  1PN5 A;  4RHW E;  2KM6 A;  4P4H A;  4O7Q A; 
#chains in the Genus database with same CATH topology
 2HM2 Q;  3QF2 A;  3CRD A;  2NAQ A;  1CWW A;  2N97 A;  2A9I A;  1N3K A;  3T6P A;  1E3Y A;  2LWE A;  3J6J A;  4F42 A;  4P4H I;  4A2W A;  4IZ5 E;  1ICH A;  4D8O A;  1DGN A;  2OF5 H;  4I16 A;  2MJM A;  1YGO A;  2A5Y B;  2DBH A;  4LWD A;  4O9L A;  3LQQ A;  1WH4 A;  2L9M A;  4M9X A;  4M9S A;  2LS7 A;  2N7Z A;  4FH0 A;  2YGS A;  4N1L A;  2YQF A;  4EWI A;  1WMG A;  2L6A A;  1CY5 A;  3EZQ B;  2YU0 A;  2MS7 A;  4N1K A;  2GF5 A;  3J63 A;  2DO9 A;  2NSN A;  1E41 A;  1NGR A;  2B1W A;  3MOP G;  4ZBW A;  2XV9 A;  2D96 A;  2VGQ A;  2O71 A;  2YVI A;  1DDF A;  2IB1 A;  3YGS P;  3YGS C;  3CL3 A;  3MOP K;  4QOB A;  2N83 A;  2DBG A;  4E9M A;  4DWN A;  1C15 A;  1A1W A;  2LWD A;  2BBZ A;  4UZ0 A;  1A1Z A;  1WXP A;  2KN6 A;  3EZQ A;  2N1F A;  3KAT A;  2DBD A;  2BBR A;  1D2Z B;  2NZ7 A;  2MN4 A;  1UCP A;  4O9F A;  2MPC A;  2N00 A;  4M9Z A;  3LQR A;  2N80 A;  4O6X A;  2MB9 A;  2P1H A;  2DBF A;  2MS8 A;  2OF5 A;  4N1J A;  4IZ7 B;  4IZA B;  4A2Q A;  4JQW A;  3MOP A;  2G7R A;  4RHW A;  1FAD A;  4JUP A;  4NQK A;  1D2Z A;  2F1S A;  2M5V A;  1Z6T A;  4F44 A;  1PN5 A;  4RHW E;  2KM6 A;  4P4H A;  4O7Q A; 
#chains in the Genus database with same CATH homology
 2HM2 Q;  3QF2 A;  3CRD A;  2NAQ A;  1CWW A;  2N97 A;  2A9I A;  1N3K A;  3T6P A;  1E3Y A;  2LWE A;  3J6J A;  4F42 A;  4P4H I;  4A2W A;  4IZ5 E;  1ICH A;  4D8O A;  1DGN A;  2OF5 H;  4I16 A;  2MJM A;  1YGO A;  2A5Y B;  2DBH A;  4LWD A;  4O9L A;  3LQQ A;  1WH4 A;  2L9M A;  4M9X A;  4M9S A;  2LS7 A;  2N7Z A;  4FH0 A;  2YGS A;  4N1L A;  2YQF A;  4EWI A;  1WMG A;  2L6A A;  1CY5 A;  3EZQ B;  2YU0 A;  2MS7 A;  4N1K A;  2GF5 A;  3J63 A;  2DO9 A;  2NSN A;  1E41 A;  1NGR A;  2B1W A;  3MOP G;  4ZBW A;  2XV9 A;  2D96 A;  2VGQ A;  2O71 A;  2YVI A;  1DDF A;  2IB1 A;  3YGS P;  3YGS C;  3CL3 A;  3MOP K;  4QOB A;  2N83 A;  2DBG A;  4E9M A;  4DWN A;  1C15 A;  1A1W A;  2LWD A;  2BBZ A;  4UZ0 A;  1A1Z A;  1WXP A;  2KN6 A;  3EZQ A;  2N1F A;  3KAT A;  2DBD A;  2BBR A;  1D2Z B;  2NZ7 A;  2MN4 A;  1UCP A;  4O9F A;  2MPC A;  2N00 A;  4M9Z A;  3LQR A;  2N80 A;  4O6X A;  2MB9 A;  2P1H A;  2DBF A;  2MS8 A;  2OF5 A;  4N1J A;  4IZ7 B;  4IZA B;  4A2Q A;  4JQW A;  3MOP A;  2G7R A;  4RHW A;  1FAD A;  4JUP A;  4NQK A;  1D2Z A;  2F1S A;  2M5V A;  1Z6T A;  4F44 A;  1PN5 A;  4RHW E;  2KM6 A;  4P4H A;  4O7Q A; 
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