3YGSC

Apaf-1 card in complex with prodomain of procaspase-9
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
95
structure length
95
Chain Sequence
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords APOPTOTIC PROTEASE ACTIVATING FACTOR 1
total genus 35
structure length 95
sequence length 95
ec nomenclature
pdb deposition date 1999-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ygsC00
4F44A 3YGSC 4P4HI 4M9SA 1A1WA 2KM6A 1C15A 2YQFA 4N1JA 2DBHA 4JUPA 1NGRA 1WXPA 2DBDA 1FADA 4M9ZA 2A5YB 2O71A 4P4HA 4IZAB 1UCPA 4I16A 3CL3A 4A2WA 3EZQB 1D2ZA 2OF5H 2NAQA 3YGSP 2M5VA 1E41A 2BBRA 3MOPG 3LQQA 4O6XA 2MS7A 2YGSA 4N1LA 2BBZA 2D96A 4O9LA 1E3YA 2LWDA 2HM2Q 2N97A 2LWEA 1A1ZA 4FH0A 4M9XA 2F1SA 2N80A 3J6JA 4D8OA 2L6AA 2NZ7A 1D2ZB 1ICHA 4UZ0A 4ZBWA 2L9MA 2IB1A 4RHWA 4E9MA 2P1HA 1CWWA 1WH4A 4A2QA 1N3KA 2DO9A 2YU0A 1YGOA 4DWNA 3LQRA 1CY5A 4IZ5E 2N1FA 2A9IA 3T6PA 2B1WA 2MS8A 4F42A 4QOBA 3CRDA 2KN6A 1WMGA 3KATA 3MOPA 4N1KA 2N00A 2MN4A 2OF5A 2N7ZA 3J63A 4RHWE 2NSNA 4IZ7B 3QF2A 4EWIA 2MB9A 2DBFA 1Z6TA 1DDFA 3MOPK 2N83A 1PN5A 2VGQA 4O9FA 2DBGA 2GF5A 4NQKA 2G7RA 4LWDA 1DGNA 2LS7A 4JQWA 2YVIA 2MPCA 3EZQA 4O7QA
chains in the Genus database with same CATH superfamily
4F44A 3YGSC 4P4HI 4M9SA 1A1WA 2KM6A 1C15A 2YQFA 4N1JA 2DBHA 4JUPA 1NGRA 1WXPA 2DBDA 1FADA 4M9ZA 2A5YB 2O71A 2XV9A 4P4HA 4IZAB 1UCPA 4I16A 3CL3A 4A2WA 3EZQB 1D2ZA 2OF5H 2NAQA 3YGSP 2M5VA 1E41A 2MJMA 2BBRA 3MOPG 3LQQA 4O6XA 2MS7A 2YGSA 4N1LA 2BBZA 2D96A 4O9LA 1E3YA 2LWDA 2HM2Q 2N97A 2LWEA 1A1ZA 4FH0A 4M9XA 2F1SA 2N80A 3J6JA 4D8OA 2L6AA 2NZ7A 1D2ZB 1ICHA 4UZ0A 4ZBWA 2L9MA 2IB1A 4RHWA 4E9MA 2P1HA 1CWWA 1WH4A 4A2QA 1N3KA 2DO9A 2YU0A 1YGOA 4DWNA 3LQRA 1CY5A 4IZ5E 2N1FA 2A9IA 3T6PA 2B1WA 2MS8A 4F42A 4QOBA 3CRDA 2KN6A 1WMGA 3KATA 3MOPA 4N1KA 2N00A 2MN4A 2OF5A 2N7ZA 3J63A 4RHWE 2NSNA 4IZ7B 3QF2A 4EWIA 2MB9A 2DBFA 1Z6TA 1DDFA 3MOPK 2N83A 1PN5A 2VGQA 4O9FA 2DBGA 2GF5A 4NQKA 2G7RA 4LWDA 1DGNA 2LS7A 4JQWA 2YVIA 2MPCA 3EZQA 4O7QA
chains in the Genus database with same CATH topology
4F44A 3YGSC 4P4HI 4M9SA 1A1WA 2KM6A 1C15A 2YQFA 4N1JA 2DBHA 4JUPA 1NGRA 1WXPA 2DBDA 1FADA 4M9ZA 2A5YB 2O71A 2XV9A 4P4HA 4IZAB 1UCPA 4I16A 3CL3A 4A2WA 3EZQB 1D2ZA 2OF5H 2NAQA 3YGSP 2M5VA 1E41A 2MJMA 2BBRA 3MOPG 3LQQA 4O6XA 2MS7A 2YGSA 4N1LA 2BBZA 2D96A 4O9LA 1E3YA 2LWDA 2HM2Q 2N97A 2LWEA 1A1ZA 4FH0A 4M9XA 2F1SA 2N80A 3J6JA 4D8OA 2L6AA 2NZ7A 1D2ZB 1ICHA 4UZ0A 4ZBWA 2L9MA 2IB1A 4RHWA 4E9MA 2P1HA 1CWWA 1WH4A 4A2QA 1N3KA 2DO9A 2YU0A 1YGOA 4DWNA 3LQRA 1CY5A 4IZ5E 2N1FA 2A9IA 3T6PA 2B1WA 2MS8A 4F42A 4QOBA 3CRDA 2KN6A 1WMGA 3KATA 3MOPA 4N1KA 2N00A 2MN4A 2OF5A 2N7ZA 3J63A 4RHWE 2NSNA 4IZ7B 3QF2A 4EWIA 2MB9A 2DBFA 1Z6TA 1DDFA 3MOPK 2N83A 1PN5A 2VGQA 4O9FA 2DBGA 2GF5A 4NQKA 2G7RA 4LWDA 1DGNA 2LS7A 4JQWA 2YVIA 2MPCA 3EZQA 4O7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F44 A;  3YGS C;  4P4H I;  4M9S A;  1A1W A;  2KM6 A;  1C15 A;  2YQF A;  4N1J A;  2DBH A;  4JUP A;  1NGR A;  1WXP A;  2DBD A;  1FAD A;  4M9Z A;  2A5Y B;  2O71 A;  4P4H A;  4IZA B;  1UCP A;  4I16 A;  3CL3 A;  4A2W A;  3EZQ B;  1D2Z A;  2OF5 H;  2NAQ A;  3YGS P;  2M5V A;  1E41 A;  2BBR A;  3MOP G;  3LQQ A;  4O6X A;  2MS7 A;  2YGS A;  4N1L A;  2BBZ A;  2D96 A;  4O9L A;  1E3Y A;  2LWD A;  2HM2 Q;  2N97 A;  2LWE A;  1A1Z A;  4FH0 A;  4M9X A;  2F1S A;  2N80 A;  3J6J A;  4D8O A;  2L6A A;  2NZ7 A;  1D2Z B;  1ICH A;  4UZ0 A;  4ZBW A;  2L9M A;  2IB1 A;  4RHW A;  4E9M A;  2P1H A;  1CWW A;  1WH4 A;  4A2Q A;  1N3K A;  2DO9 A;  2YU0 A;  1YGO A;  4DWN A;  3LQR A;  1CY5 A;  4IZ5 E;  2N1F A;  2A9I A;  3T6P A;  2B1W A;  2MS8 A;  4F42 A;  4QOB A;  3CRD A;  2KN6 A;  1WMG A;  3KAT A;  3MOP A;  4N1K A;  2N00 A;  2MN4 A;  2OF5 A;  2N7Z A;  3J63 A;  4RHW E;  2NSN A;  4IZ7 B;  3QF2 A;  4EWI A;  2MB9 A;  2DBF A;  1Z6T A;  1DDF A;  3MOP K;  2N83 A;  1PN5 A;  2VGQ A;  4O9F A;  2DBG A;  2GF5 A;  4NQK A;  2G7R A;  4LWD A;  1DGN A;  2LS7 A;  4JQW A;  2YVI A;  2MPC A;  3EZQ A;  4O7Q A; 
#chains in the Genus database with same CATH topology
 4F44 A;  3YGS C;  4P4H I;  4M9S A;  1A1W A;  2KM6 A;  1C15 A;  2YQF A;  4N1J A;  2DBH A;  4JUP A;  1NGR A;  1WXP A;  2DBD A;  1FAD A;  4M9Z A;  2A5Y B;  2O71 A;  2XV9 A;  4P4H A;  4IZA B;  1UCP A;  4I16 A;  3CL3 A;  4A2W A;  3EZQ B;  1D2Z A;  2OF5 H;  2NAQ A;  3YGS P;  2M5V A;  1E41 A;  2MJM A;  2BBR A;  3MOP G;  3LQQ A;  4O6X A;  2MS7 A;  2YGS A;  4N1L A;  2BBZ A;  2D96 A;  4O9L A;  1E3Y A;  2LWD A;  2HM2 Q;  2N97 A;  2LWE A;  1A1Z A;  4FH0 A;  4M9X A;  2F1S A;  2N80 A;  3J6J A;  4D8O A;  2L6A A;  2NZ7 A;  1D2Z B;  1ICH A;  4UZ0 A;  4ZBW A;  2L9M A;  2IB1 A;  4RHW A;  4E9M A;  2P1H A;  1CWW A;  1WH4 A;  4A2Q A;  1N3K A;  2DO9 A;  2YU0 A;  1YGO A;  4DWN A;  3LQR A;  1CY5 A;  4IZ5 E;  2N1F A;  2A9I A;  3T6P A;  2B1W A;  2MS8 A;  4F42 A;  4QOB A;  3CRD A;  2KN6 A;  1WMG A;  3KAT A;  3MOP A;  4N1K A;  2N00 A;  2MN4 A;  2OF5 A;  2N7Z A;  3J63 A;  4RHW E;  2NSN A;  4IZ7 B;  3QF2 A;  4EWI A;  2MB9 A;  2DBF A;  1Z6T A;  1DDF A;  3MOP K;  2N83 A;  1PN5 A;  2VGQ A;  4O9F A;  2DBG A;  2GF5 A;  4NQK A;  2G7R A;  4LWD A;  1DGN A;  2LS7 A;  4JQW A;  2YVI A;  2MPC A;  3EZQ A;  4O7Q A; 
#chains in the Genus database with same CATH homology
 4F44 A;  3YGS C;  4P4H I;  4M9S A;  1A1W A;  2KM6 A;  1C15 A;  2YQF A;  4N1J A;  2DBH A;  4JUP A;  1NGR A;  1WXP A;  2DBD A;  1FAD A;  4M9Z A;  2A5Y B;  2O71 A;  2XV9 A;  4P4H A;  4IZA B;  1UCP A;  4I16 A;  3CL3 A;  4A2W A;  3EZQ B;  1D2Z A;  2OF5 H;  2NAQ A;  3YGS P;  2M5V A;  1E41 A;  2MJM A;  2BBR A;  3MOP G;  3LQQ A;  4O6X A;  2MS7 A;  2YGS A;  4N1L A;  2BBZ A;  2D96 A;  4O9L A;  1E3Y A;  2LWD A;  2HM2 Q;  2N97 A;  2LWE A;  1A1Z A;  4FH0 A;  4M9X A;  2F1S A;  2N80 A;  3J6J A;  4D8O A;  2L6A A;  2NZ7 A;  1D2Z B;  1ICH A;  4UZ0 A;  4ZBW A;  2L9M A;  2IB1 A;  4RHW A;  4E9M A;  2P1H A;  1CWW A;  1WH4 A;  4A2Q A;  1N3K A;  2DO9 A;  2YU0 A;  1YGO A;  4DWN A;  3LQR A;  1CY5 A;  4IZ5 E;  2N1F A;  2A9I A;  3T6P A;  2B1W A;  2MS8 A;  4F42 A;  4QOB A;  3CRD A;  2KN6 A;  1WMG A;  3KAT A;  3MOP A;  4N1K A;  2N00 A;  2MN4 A;  2OF5 A;  2N7Z A;  3J63 A;  4RHW E;  2NSN A;  4IZ7 B;  3QF2 A;  4EWI A;  2MB9 A;  2DBF A;  1Z6T A;  1DDF A;  3MOP K;  2N83 A;  1PN5 A;  2VGQ A;  4O9F A;  2DBG A;  2GF5 A;  4NQK A;  2G7R A;  4LWD A;  1DGN A;  2LS7 A;  4JQW A;  2YVI A;  2MPC A;  3EZQ A;  4O7Q A; 
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similar chains in the pdb database (?% sequence similarity)

 
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