3YGSC

Apaf-1 card in complex with prodomain of procaspase-9
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
95
structure length
95
Chain Sequence
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Apoptosis
molecule keywords APOPTOTIC PROTEASE ACTIVATING FACTOR 1
total genus 35
structure length 95
sequence length 95
ec nomenclature
pdb deposition date 1999-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ygsC00
2OF5H 4IZ5E 4IZ7B 4N1JA 4A2QA 2IB1A 2DBGA 2LWDA 1D2ZA 2A9IA 1A1WA 2M5VA 2DO9A 2BBRA 2LWEA 3YGSP 2NAQA 2MS8A 4A2WA 3KATA 2KN6A 2VGQA 3MOPK 2MN4A 3CRDA 3EZQA 3LQQA 1C15A 2NZ7A 4LWDA 2B1WA 4UZ0A 2BBZA 4O9FA 4F42A 2N83A 4P4HA 3LQRA 3J6JA 1WMGA 2N80A 4RHWA 4F44A 2KM6A 1Z6TA 4NQKA 2N1FA 1N3KA 2NSNA 4JUPA 2N00A 3T6PA 1WXPA 4IZAB 3EZQB 2MB9A 2YU0A 3MOPA 4I16A 2DBFA 2D96A 2G7RA 3QF2A 4ZBWA 2HM2Q 4E9MA 1PN5A 2DBHA 2MPCA 1CY5A 2YGSA 4M9ZA 2GF5A 3YGSC 1WH4A 2YVIA 3J63A 4RHWE 1FADA 2L6AA 2N7ZA 1ICHA 4P4HI 2DBDA 1A1ZA 4FH0A 4O6XA 3MOPG 1YGOA 4N1LA 4M9SA 2A5YB 1E3YA 1NGRA 2LS7A 2O71A 4EWIA 1CWWA 1DGNA 4JQWA 4M9XA 4N1KA 2L9MA 3CL3A 2MS7A 1UCPA 2N97A 2P1HA 1D2ZB 4QOBA 4O9LA 1DDFA 4D8OA 2F1SA 2OF5A 1E41A 4O7QA 2YQFA 4DWNA
chains in the Genus database with same CATH superfamily
2OF5H 4IZ5E 4IZ7B 4N1JA 4A2QA 2IB1A 2DBGA 2LWDA 1D2ZA 2A9IA 1A1WA 2M5VA 2DO9A 2BBRA 2LWEA 3YGSP 2NAQA 2MS8A 4A2WA 3KATA 2KN6A 2VGQA 3MOPK 2MN4A 3CRDA 3EZQA 3LQQA 1C15A 2NZ7A 4LWDA 2B1WA 4UZ0A 2BBZA 4O9FA 4F42A 2N83A 4P4HA 3LQRA 3J6JA 1WMGA 2N80A 4RHWA 4F44A 2KM6A 1Z6TA 4NQKA 2N1FA 1N3KA 2NSNA 4JUPA 2N00A 3T6PA 1WXPA 4IZAB 3EZQB 2MB9A 2YU0A 2XV9A 3MOPA 4I16A 2DBFA 2D96A 2G7RA 3QF2A 4ZBWA 2HM2Q 2MJMA 4E9MA 1PN5A 2DBHA 2MPCA 1CY5A 2YGSA 4M9ZA 2GF5A 3YGSC 1WH4A 2YVIA 3J63A 4RHWE 1FADA 2L6AA 2N7ZA 1ICHA 4P4HI 2DBDA 1A1ZA 4FH0A 4O6XA 3MOPG 1YGOA 4N1LA 4M9SA 2A5YB 1E3YA 1NGRA 2LS7A 2O71A 4EWIA 1CWWA 1DGNA 4JQWA 4M9XA 4N1KA 2L9MA 3CL3A 2MS7A 1UCPA 2N97A 2P1HA 1D2ZB 4QOBA 4O9LA 1DDFA 4D8OA 2F1SA 2OF5A 1E41A 4O7QA 2YQFA 4DWNA
chains in the Genus database with same CATH topology
2OF5H 4IZ5E 4IZ7B 4N1JA 4A2QA 2IB1A 2DBGA 2LWDA 1D2ZA 2A9IA 1A1WA 2M5VA 2DO9A 2BBRA 2LWEA 3YGSP 2NAQA 2MS8A 4A2WA 3KATA 2KN6A 2VGQA 3MOPK 2MN4A 3CRDA 3EZQA 3LQQA 1C15A 2NZ7A 4LWDA 2B1WA 4UZ0A 2BBZA 4O9FA 4F42A 2N83A 4P4HA 3LQRA 3J6JA 1WMGA 2N80A 4RHWA 4F44A 2KM6A 1Z6TA 4NQKA 2N1FA 1N3KA 2NSNA 4JUPA 2N00A 3T6PA 1WXPA 4IZAB 3EZQB 2MB9A 2YU0A 2XV9A 3MOPA 4I16A 2DBFA 2D96A 2G7RA 3QF2A 4ZBWA 2HM2Q 2MJMA 4E9MA 1PN5A 2DBHA 2MPCA 1CY5A 2YGSA 4M9ZA 2GF5A 3YGSC 1WH4A 2YVIA 3J63A 4RHWE 1FADA 2L6AA 2N7ZA 1ICHA 4P4HI 2DBDA 1A1ZA 4FH0A 4O6XA 3MOPG 1YGOA 4N1LA 4M9SA 2A5YB 1E3YA 1NGRA 2LS7A 2O71A 4EWIA 1CWWA 1DGNA 4JQWA 4M9XA 4N1KA 2L9MA 3CL3A 2MS7A 1UCPA 2N97A 2P1HA 1D2ZB 4QOBA 4O9LA 1DDFA 4D8OA 2F1SA 2OF5A 1E41A 4O7QA 2YQFA 4DWNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OF5 H;  4IZ5 E;  4IZ7 B;  4N1J A;  4A2Q A;  2IB1 A;  2DBG A;  2LWD A;  1D2Z A;  2A9I A;  1A1W A;  2M5V A;  2DO9 A;  2BBR A;  2LWE A;  3YGS P;  2NAQ A;  2MS8 A;  4A2W A;  3KAT A;  2KN6 A;  2VGQ A;  3MOP K;  2MN4 A;  3CRD A;  3EZQ A;  3LQQ A;  1C15 A;  2NZ7 A;  4LWD A;  2B1W A;  4UZ0 A;  2BBZ A;  4O9F A;  4F42 A;  2N83 A;  4P4H A;  3LQR A;  3J6J A;  1WMG A;  2N80 A;  4RHW A;  4F44 A;  2KM6 A;  1Z6T A;  4NQK A;  2N1F A;  1N3K A;  2NSN A;  4JUP A;  2N00 A;  3T6P A;  1WXP A;  4IZA B;  3EZQ B;  2MB9 A;  2YU0 A;  3MOP A;  4I16 A;  2DBF A;  2D96 A;  2G7R A;  3QF2 A;  4ZBW A;  2HM2 Q;  4E9M A;  1PN5 A;  2DBH A;  2MPC A;  1CY5 A;  2YGS A;  4M9Z A;  2GF5 A;  3YGS C;  1WH4 A;  2YVI A;  3J63 A;  4RHW E;  1FAD A;  2L6A A;  2N7Z A;  1ICH A;  4P4H I;  2DBD A;  1A1Z A;  4FH0 A;  4O6X A;  3MOP G;  1YGO A;  4N1L A;  4M9S A;  2A5Y B;  1E3Y A;  1NGR A;  2LS7 A;  2O71 A;  4EWI A;  1CWW A;  1DGN A;  4JQW A;  4M9X A;  4N1K A;  2L9M A;  3CL3 A;  2MS7 A;  1UCP A;  2N97 A;  2P1H A;  1D2Z B;  4QOB A;  4O9L A;  1DDF A;  4D8O A;  2F1S A;  2OF5 A;  1E41 A;  4O7Q A;  2YQF A;  4DWN A; 
#chains in the Genus database with same CATH topology
 2OF5 H;  4IZ5 E;  4IZ7 B;  4N1J A;  4A2Q A;  2IB1 A;  2DBG A;  2LWD A;  1D2Z A;  2A9I A;  1A1W A;  2M5V A;  2DO9 A;  2BBR A;  2LWE A;  3YGS P;  2NAQ A;  2MS8 A;  4A2W A;  3KAT A;  2KN6 A;  2VGQ A;  3MOP K;  2MN4 A;  3CRD A;  3EZQ A;  3LQQ A;  1C15 A;  2NZ7 A;  4LWD A;  2B1W A;  4UZ0 A;  2BBZ A;  4O9F A;  4F42 A;  2N83 A;  4P4H A;  3LQR A;  3J6J A;  1WMG A;  2N80 A;  4RHW A;  4F44 A;  2KM6 A;  1Z6T A;  4NQK A;  2N1F A;  1N3K A;  2NSN A;  4JUP A;  2N00 A;  3T6P A;  1WXP A;  4IZA B;  3EZQ B;  2MB9 A;  2YU0 A;  2XV9 A;  3MOP A;  4I16 A;  2DBF A;  2D96 A;  2G7R A;  3QF2 A;  4ZBW A;  2HM2 Q;  2MJM A;  4E9M A;  1PN5 A;  2DBH A;  2MPC A;  1CY5 A;  2YGS A;  4M9Z A;  2GF5 A;  3YGS C;  1WH4 A;  2YVI A;  3J63 A;  4RHW E;  1FAD A;  2L6A A;  2N7Z A;  1ICH A;  4P4H I;  2DBD A;  1A1Z A;  4FH0 A;  4O6X A;  3MOP G;  1YGO A;  4N1L A;  4M9S A;  2A5Y B;  1E3Y A;  1NGR A;  2LS7 A;  2O71 A;  4EWI A;  1CWW A;  1DGN A;  4JQW A;  4M9X A;  4N1K A;  2L9M A;  3CL3 A;  2MS7 A;  1UCP A;  2N97 A;  2P1H A;  1D2Z B;  4QOB A;  4O9L A;  1DDF A;  4D8O A;  2F1S A;  2OF5 A;  1E41 A;  4O7Q A;  2YQF A;  4DWN A; 
#chains in the Genus database with same CATH homology
 2OF5 H;  4IZ5 E;  4IZ7 B;  4N1J A;  4A2Q A;  2IB1 A;  2DBG A;  2LWD A;  1D2Z A;  2A9I A;  1A1W A;  2M5V A;  2DO9 A;  2BBR A;  2LWE A;  3YGS P;  2NAQ A;  2MS8 A;  4A2W A;  3KAT A;  2KN6 A;  2VGQ A;  3MOP K;  2MN4 A;  3CRD A;  3EZQ A;  3LQQ A;  1C15 A;  2NZ7 A;  4LWD A;  2B1W A;  4UZ0 A;  2BBZ A;  4O9F A;  4F42 A;  2N83 A;  4P4H A;  3LQR A;  3J6J A;  1WMG A;  2N80 A;  4RHW A;  4F44 A;  2KM6 A;  1Z6T A;  4NQK A;  2N1F A;  1N3K A;  2NSN A;  4JUP A;  2N00 A;  3T6P A;  1WXP A;  4IZA B;  3EZQ B;  2MB9 A;  2YU0 A;  2XV9 A;  3MOP A;  4I16 A;  2DBF A;  2D96 A;  2G7R A;  3QF2 A;  4ZBW A;  2HM2 Q;  2MJM A;  4E9M A;  1PN5 A;  2DBH A;  2MPC A;  1CY5 A;  2YGS A;  4M9Z A;  2GF5 A;  3YGS C;  1WH4 A;  2YVI A;  3J63 A;  4RHW E;  1FAD A;  2L6A A;  2N7Z A;  1ICH A;  4P4H I;  2DBD A;  1A1Z A;  4FH0 A;  4O6X A;  3MOP G;  1YGO A;  4N1L A;  4M9S A;  2A5Y B;  1E3Y A;  1NGR A;  2LS7 A;  2O71 A;  4EWI A;  1CWW A;  1DGN A;  4JQW A;  4M9X A;  4N1K A;  2L9M A;  3CL3 A;  2MS7 A;  1UCP A;  2N97 A;  2P1H A;  1D2Z B;  4QOB A;  4O9L A;  1DDF A;  4D8O A;  2F1S A;  2OF5 A;  1E41 A;  4O7Q A;  2YQF A;  4DWN A; 
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similar chains in the pdb database (?% sequence similarity)

 
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