3YGSP

Apaf-1 card in complex with prodomain of procaspase-9
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
SMDEADRRLLRRCRLRLVEELQVDQLWDVLLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords APOPTOTIC PROTEASE ACTIVATING FACTOR 1
total genus 38
structure length 97
sequence length 97
ec nomenclature ec 3.4.22.62: Caspase-9.
pdb deposition date 1999-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ygsP00
2KM6A 4UZ0A 2B1WA 1CY5A 4A2WA 1Z6TA 2VGQA 3LQRA 3MOPA 4M9XA 2LS7A 3KATA 2A5YB 4O9FA 4IZAB 4DWNA 2BBZA 1WH4A 3CRDA 1YGOA 2N1FA 4O6XA 2KN6A 2P1HA 3MOPK 2GF5A 3MOPG 2MPCA 2MS7A 2L9MA 2LWDA 2DBHA 2IB1A 2DBDA 4QOBA 1A1ZA 2G7RA 4EWIA 3QF2A 3YGSC 1WMGA 4LWDA 4D8OA 4RHWA 1NGRA 2M5VA 2L6AA 4O7QA 3LQQA 4RHWE 3CL3A 4JQWA 4O9LA 2NSNA 4NQKA 2D96A 1E3YA 4E9MA 2MB9A 1N3KA 3J6JA 2F1SA 2BBRA 4N1LA 4M9ZA 2YQFA 4P4HI 3EZQB 2N00A 4IZ7B 2YVIA 2MN4A 2DBFA 2O71A 1PN5A 3T6PA 2NZ7A 1UCPA 3J63A 2NAQA 2N97A 1DGNA 2LWEA 4M9SA 1FADA 4F44A 1CWWA 4N1JA 4JUPA 2N80A 3EZQA 2YGSA 4FH0A 1A1WA 2OF5A 2HM2Q 1D2ZB 4I16A 2MS8A 3YGSP 1WXPA 4IZ5E 2N7ZA 1C15A 4F42A 2DO9A 4N1KA 2N83A 1ICHA 2A9IA 4ZBWA 1DDFA 2DBGA 4A2QA 2OF5H 4P4HA 2YU0A 1D2ZA 1E41A
chains in the Genus database with same CATH superfamily
2KM6A 4UZ0A 2B1WA 1CY5A 4A2WA 1Z6TA 2VGQA 3LQRA 3MOPA 4M9XA 2LS7A 3KATA 2A5YB 4O9FA 4IZAB 4DWNA 2BBZA 1WH4A 3CRDA 1YGOA 2N1FA 4O6XA 2KN6A 2P1HA 3MOPK 2GF5A 3MOPG 2MPCA 2MS7A 2L9MA 2LWDA 2DBHA 2IB1A 2DBDA 4QOBA 1A1ZA 2G7RA 4EWIA 3QF2A 3YGSC 1WMGA 4LWDA 4D8OA 4RHWA 1NGRA 2M5VA 2L6AA 4O7QA 3LQQA 4RHWE 3CL3A 4JQWA 4O9LA 2NSNA 4NQKA 2D96A 1E3YA 4E9MA 2MB9A 1N3KA 3J6JA 2F1SA 2BBRA 4N1LA 4M9ZA 2YQFA 4P4HI 3EZQB 2N00A 4IZ7B 2YVIA 2MN4A 2DBFA 2O71A 1PN5A 3T6PA 2NZ7A 1UCPA 3J63A 2NAQA 2N97A 1DGNA 2LWEA 4M9SA 1FADA 4F44A 1CWWA 4N1JA 4JUPA 2N80A 3EZQA 2YGSA 4FH0A 1A1WA 2OF5A 2HM2Q 1D2ZB 4I16A 2MS8A 3YGSP 1WXPA 2XV9A 4IZ5E 2N7ZA 1C15A 2MJMA 4F42A 2DO9A 4N1KA 2N83A 1ICHA 2A9IA 4ZBWA 1DDFA 2DBGA 4A2QA 2OF5H 4P4HA 2YU0A 1D2ZA 1E41A
chains in the Genus database with same CATH topology
2KM6A 4UZ0A 2B1WA 1CY5A 4A2WA 1Z6TA 2VGQA 3LQRA 3MOPA 4M9XA 2LS7A 3KATA 2A5YB 4O9FA 4IZAB 4DWNA 2BBZA 1WH4A 3CRDA 1YGOA 2N1FA 4O6XA 2KN6A 2P1HA 3MOPK 2GF5A 3MOPG 2MPCA 2MS7A 2L9MA 2LWDA 2DBHA 2IB1A 2DBDA 4QOBA 1A1ZA 2G7RA 4EWIA 3QF2A 3YGSC 1WMGA 4LWDA 4D8OA 4RHWA 1NGRA 2M5VA 2L6AA 4O7QA 3LQQA 4RHWE 3CL3A 4JQWA 4O9LA 2NSNA 4NQKA 2D96A 1E3YA 4E9MA 2MB9A 1N3KA 3J6JA 2F1SA 2BBRA 4N1LA 4M9ZA 2YQFA 4P4HI 3EZQB 2N00A 4IZ7B 2YVIA 2MN4A 2DBFA 2O71A 1PN5A 3T6PA 2NZ7A 1UCPA 3J63A 2NAQA 2N97A 1DGNA 2LWEA 4M9SA 1FADA 4F44A 1CWWA 4N1JA 4JUPA 2N80A 3EZQA 2YGSA 4FH0A 1A1WA 2OF5A 2HM2Q 1D2ZB 4I16A 2MS8A 3YGSP 1WXPA 2XV9A 4IZ5E 2N7ZA 1C15A 2MJMA 4F42A 2DO9A 4N1KA 2N83A 1ICHA 2A9IA 4ZBWA 1DDFA 2DBGA 4A2QA 2OF5H 4P4HA 2YU0A 1D2ZA 1E41A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2KM6 A;  4UZ0 A;  2B1W A;  1CY5 A;  4A2W A;  1Z6T A;  2VGQ A;  3LQR A;  3MOP A;  4M9X A;  2LS7 A;  3KAT A;  2A5Y B;  4O9F A;  4IZA B;  4DWN A;  2BBZ A;  1WH4 A;  3CRD A;  1YGO A;  2N1F A;  4O6X A;  2KN6 A;  2P1H A;  3MOP K;  2GF5 A;  3MOP G;  2MPC A;  2MS7 A;  2L9M A;  2LWD A;  2DBH A;  2IB1 A;  2DBD A;  4QOB A;  1A1Z A;  2G7R A;  4EWI A;  3QF2 A;  3YGS C;  1WMG A;  4LWD A;  4D8O A;  4RHW A;  1NGR A;  2M5V A;  2L6A A;  4O7Q A;  3LQQ A;  4RHW E;  3CL3 A;  4JQW A;  4O9L A;  2NSN A;  4NQK A;  2D96 A;  1E3Y A;  4E9M A;  2MB9 A;  1N3K A;  3J6J A;  2F1S A;  2BBR A;  4N1L A;  4M9Z A;  2YQF A;  4P4H I;  3EZQ B;  2N00 A;  4IZ7 B;  2YVI A;  2MN4 A;  2DBF A;  2O71 A;  1PN5 A;  3T6P A;  2NZ7 A;  1UCP A;  3J63 A;  2NAQ A;  2N97 A;  1DGN A;  2LWE A;  4M9S A;  1FAD A;  4F44 A;  1CWW A;  4N1J A;  4JUP A;  2N80 A;  3EZQ A;  2YGS A;  4FH0 A;  1A1W A;  2OF5 A;  2HM2 Q;  1D2Z B;  4I16 A;  2MS8 A;  3YGS P;  1WXP A;  4IZ5 E;  2N7Z A;  1C15 A;  4F42 A;  2DO9 A;  4N1K A;  2N83 A;  1ICH A;  2A9I A;  4ZBW A;  1DDF A;  2DBG A;  4A2Q A;  2OF5 H;  4P4H A;  2YU0 A;  1D2Z A;  1E41 A; 
#chains in the Genus database with same CATH topology
 2KM6 A;  4UZ0 A;  2B1W A;  1CY5 A;  4A2W A;  1Z6T A;  2VGQ A;  3LQR A;  3MOP A;  4M9X A;  2LS7 A;  3KAT A;  2A5Y B;  4O9F A;  4IZA B;  4DWN A;  2BBZ A;  1WH4 A;  3CRD A;  1YGO A;  2N1F A;  4O6X A;  2KN6 A;  2P1H A;  3MOP K;  2GF5 A;  3MOP G;  2MPC A;  2MS7 A;  2L9M A;  2LWD A;  2DBH A;  2IB1 A;  2DBD A;  4QOB A;  1A1Z A;  2G7R A;  4EWI A;  3QF2 A;  3YGS C;  1WMG A;  4LWD A;  4D8O A;  4RHW A;  1NGR A;  2M5V A;  2L6A A;  4O7Q A;  3LQQ A;  4RHW E;  3CL3 A;  4JQW A;  4O9L A;  2NSN A;  4NQK A;  2D96 A;  1E3Y A;  4E9M A;  2MB9 A;  1N3K A;  3J6J A;  2F1S A;  2BBR A;  4N1L A;  4M9Z A;  2YQF A;  4P4H I;  3EZQ B;  2N00 A;  4IZ7 B;  2YVI A;  2MN4 A;  2DBF A;  2O71 A;  1PN5 A;  3T6P A;  2NZ7 A;  1UCP A;  3J63 A;  2NAQ A;  2N97 A;  1DGN A;  2LWE A;  4M9S A;  1FAD A;  4F44 A;  1CWW A;  4N1J A;  4JUP A;  2N80 A;  3EZQ A;  2YGS A;  4FH0 A;  1A1W A;  2OF5 A;  2HM2 Q;  1D2Z B;  4I16 A;  2MS8 A;  3YGS P;  1WXP A;  2XV9 A;  4IZ5 E;  2N7Z A;  1C15 A;  2MJM A;  4F42 A;  2DO9 A;  4N1K A;  2N83 A;  1ICH A;  2A9I A;  4ZBW A;  1DDF A;  2DBG A;  4A2Q A;  2OF5 H;  4P4H A;  2YU0 A;  1D2Z A;  1E41 A; 
#chains in the Genus database with same CATH homology
 2KM6 A;  4UZ0 A;  2B1W A;  1CY5 A;  4A2W A;  1Z6T A;  2VGQ A;  3LQR A;  3MOP A;  4M9X A;  2LS7 A;  3KAT A;  2A5Y B;  4O9F A;  4IZA B;  4DWN A;  2BBZ A;  1WH4 A;  3CRD A;  1YGO A;  2N1F A;  4O6X A;  2KN6 A;  2P1H A;  3MOP K;  2GF5 A;  3MOP G;  2MPC A;  2MS7 A;  2L9M A;  2LWD A;  2DBH A;  2IB1 A;  2DBD A;  4QOB A;  1A1Z A;  2G7R A;  4EWI A;  3QF2 A;  3YGS C;  1WMG A;  4LWD A;  4D8O A;  4RHW A;  1NGR A;  2M5V A;  2L6A A;  4O7Q A;  3LQQ A;  4RHW E;  3CL3 A;  4JQW A;  4O9L A;  2NSN A;  4NQK A;  2D96 A;  1E3Y A;  4E9M A;  2MB9 A;  1N3K A;  3J6J A;  2F1S A;  2BBR A;  4N1L A;  4M9Z A;  2YQF A;  4P4H I;  3EZQ B;  2N00 A;  4IZ7 B;  2YVI A;  2MN4 A;  2DBF A;  2O71 A;  1PN5 A;  3T6P A;  2NZ7 A;  1UCP A;  3J63 A;  2NAQ A;  2N97 A;  1DGN A;  2LWE A;  4M9S A;  1FAD A;  4F44 A;  1CWW A;  4N1J A;  4JUP A;  2N80 A;  3EZQ A;  2YGS A;  4FH0 A;  1A1W A;  2OF5 A;  2HM2 Q;  1D2Z B;  4I16 A;  2MS8 A;  3YGS P;  1WXP A;  2XV9 A;  4IZ5 E;  2N7Z A;  1C15 A;  2MJM A;  4F42 A;  2DO9 A;  4N1K A;  2N83 A;  1ICH A;  2A9I A;  4ZBW A;  1DDF A;  2DBG A;  4A2Q A;  2OF5 H;  4P4H A;  2YU0 A;  1D2Z A;  1E41 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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