3EZQA

Crystal structure of the fas/fadd death domain complex
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
115
structure length
115
Chain Sequence
NLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSLVLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Fas-FADD death domain complex structure unravels signalling by receptor clustering
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 6
total genus 43
structure length 115
sequence length 115
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2008-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ezqA00
4RHWA 4F44A 2M5VA 4IZ5E 4N1KA 2KN6A 2G7RA 4D8OA 3EZQB 2MN4A 4QOBA 3J63A 4FH0A 4P4HI 2DBHA 1WH4A 4O7QA 3T6PA 2LS7A 2MB9A 1Z6TA 2OF5A 4DWNA 4ZBWA 2F1SA 1UCPA 2NSNA 2N7ZA 1CY5A 3YGSP 1FADA 2A9IA 2L9MA 1NGRA 4NQKA 3CL3A 2L6AA 1A1ZA 3MOPG 4UZ0A 2LWDA 1DDFA 4RHWE 2HM2Q 2MPCA 4M9SA 4JQWA 4LWDA 4N1LA 2MS8A 4F42A 3QF2A 2VGQA 4JUPA 1WMGA 3MOPA 1WXPA 4P4HA 2OF5H 3J6JA 2DBDA 3YGSC 1E41A 1C15A 3LQQA 4IZ7B 2N80A 2IB1A 1A1WA 2DBGA 1ICHA 1N3KA 2YGSA 2N83A 2A5YB 1YGOA 4O9FA 4O6XA 2BBZA 2B1WA 3KATA 4A2WA 4A2QA 3LQRA 1D2ZB 2LWEA 4N1JA 3MOPK 2O71A 4O9LA 4EWIA 2YQFA 2GF5A 2NZ7A 1PN5A 2YU0A 1CWWA 2D96A 2MS7A 2DO9A 1D2ZA 1DGNA 2N97A 2N00A 4I16A 4M9XA 2P1HA 2KM6A 3EZQA 4IZAB 2YVIA 2BBRA 4M9ZA 2DBFA 3CRDA 2N1FA 2NAQA 1E3YA 4E9MA
chains in the Genus database with same CATH superfamily
4RHWA 4F44A 2M5VA 4IZ5E 4N1KA 2KN6A 2G7RA 4D8OA 3EZQB 2MN4A 4QOBA 3J63A 4FH0A 4P4HI 2DBHA 1WH4A 4O7QA 3T6PA 2MJMA 2LS7A 2MB9A 1Z6TA 2OF5A 4DWNA 4ZBWA 2F1SA 1UCPA 2NSNA 2N7ZA 1CY5A 3YGSP 1FADA 2A9IA 2L9MA 1NGRA 4NQKA 3CL3A 2L6AA 1A1ZA 3MOPG 4UZ0A 2LWDA 1DDFA 4RHWE 2HM2Q 2MPCA 4M9SA 4JQWA 4LWDA 4N1LA 2MS8A 4F42A 3QF2A 2VGQA 4JUPA 1WMGA 3MOPA 1WXPA 4P4HA 2OF5H 3J6JA 2DBDA 3YGSC 1E41A 1C15A 3LQQA 4IZ7B 2N80A 2IB1A 1A1WA 2DBGA 1ICHA 1N3KA 2YGSA 2N83A 2A5YB 1YGOA 4O9FA 4O6XA 2BBZA 2B1WA 3KATA 4A2WA 4A2QA 3LQRA 2XV9A 1D2ZB 2LWEA 4N1JA 3MOPK 2O71A 4O9LA 4EWIA 2YQFA 2GF5A 2NZ7A 1PN5A 2YU0A 1CWWA 2D96A 2MS7A 2DO9A 1D2ZA 1DGNA 2N97A 2N00A 4I16A 4M9XA 2P1HA 2KM6A 3EZQA 4IZAB 2YVIA 2BBRA 4M9ZA 2DBFA 3CRDA 2N1FA 2NAQA 1E3YA 4E9MA
chains in the Genus database with same CATH topology
4RHWA 4F44A 2M5VA 4IZ5E 4N1KA 2KN6A 2G7RA 4D8OA 3EZQB 2MN4A 4QOBA 3J63A 4FH0A 4P4HI 2DBHA 1WH4A 4O7QA 3T6PA 2MJMA 2LS7A 2MB9A 1Z6TA 2OF5A 4DWNA 4ZBWA 2F1SA 1UCPA 2NSNA 2N7ZA 1CY5A 3YGSP 1FADA 2A9IA 2L9MA 1NGRA 4NQKA 3CL3A 2L6AA 1A1ZA 3MOPG 4UZ0A 2LWDA 1DDFA 4RHWE 2HM2Q 2MPCA 4M9SA 4JQWA 4LWDA 4N1LA 2MS8A 4F42A 3QF2A 2VGQA 4JUPA 1WMGA 3MOPA 1WXPA 4P4HA 2OF5H 3J6JA 2DBDA 3YGSC 1E41A 1C15A 3LQQA 4IZ7B 2N80A 2IB1A 1A1WA 2DBGA 1ICHA 1N3KA 2YGSA 2N83A 2A5YB 1YGOA 4O9FA 4O6XA 2BBZA 2B1WA 3KATA 4A2WA 4A2QA 3LQRA 2XV9A 1D2ZB 2LWEA 4N1JA 3MOPK 2O71A 4O9LA 4EWIA 2YQFA 2GF5A 2NZ7A 1PN5A 2YU0A 1CWWA 2D96A 2MS7A 2DO9A 1D2ZA 1DGNA 2N97A 2N00A 4I16A 4M9XA 2P1HA 2KM6A 3EZQA 4IZAB 2YVIA 2BBRA 4M9ZA 2DBFA 3CRDA 2N1FA 2NAQA 1E3YA 4E9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RHW A;  4F44 A;  2M5V A;  4IZ5 E;  4N1K A;  2KN6 A;  2G7R A;  4D8O A;  3EZQ B;  2MN4 A;  4QOB A;  3J63 A;  4FH0 A;  4P4H I;  2DBH A;  1WH4 A;  4O7Q A;  3T6P A;  2LS7 A;  2MB9 A;  1Z6T A;  2OF5 A;  4DWN A;  4ZBW A;  2F1S A;  1UCP A;  2NSN A;  2N7Z A;  1CY5 A;  3YGS P;  1FAD A;  2A9I A;  2L9M A;  1NGR A;  4NQK A;  3CL3 A;  2L6A A;  1A1Z A;  3MOP G;  4UZ0 A;  2LWD A;  1DDF A;  4RHW E;  2HM2 Q;  2MPC A;  4M9S A;  4JQW A;  4LWD A;  4N1L A;  2MS8 A;  4F42 A;  3QF2 A;  2VGQ A;  4JUP A;  1WMG A;  3MOP A;  1WXP A;  4P4H A;  2OF5 H;  3J6J A;  2DBD A;  3YGS C;  1E41 A;  1C15 A;  3LQQ A;  4IZ7 B;  2N80 A;  2IB1 A;  1A1W A;  2DBG A;  1ICH A;  1N3K A;  2YGS A;  2N83 A;  2A5Y B;  1YGO A;  4O9F A;  4O6X A;  2BBZ A;  2B1W A;  3KAT A;  4A2W A;  4A2Q A;  3LQR A;  1D2Z B;  2LWE A;  4N1J A;  3MOP K;  2O71 A;  4O9L A;  4EWI A;  2YQF A;  2GF5 A;  2NZ7 A;  1PN5 A;  2YU0 A;  1CWW A;  2D96 A;  2MS7 A;  2DO9 A;  1D2Z A;  1DGN A;  2N97 A;  2N00 A;  4I16 A;  4M9X A;  2P1H A;  2KM6 A;  3EZQ A;  4IZA B;  2YVI A;  2BBR A;  4M9Z A;  2DBF A;  3CRD A;  2N1F A;  2NAQ A;  1E3Y A;  4E9M A; 
#chains in the Genus database with same CATH topology
 4RHW A;  4F44 A;  2M5V A;  4IZ5 E;  4N1K A;  2KN6 A;  2G7R A;  4D8O A;  3EZQ B;  2MN4 A;  4QOB A;  3J63 A;  4FH0 A;  4P4H I;  2DBH A;  1WH4 A;  4O7Q A;  3T6P A;  2MJM A;  2LS7 A;  2MB9 A;  1Z6T A;  2OF5 A;  4DWN A;  4ZBW A;  2F1S A;  1UCP A;  2NSN A;  2N7Z A;  1CY5 A;  3YGS P;  1FAD A;  2A9I A;  2L9M A;  1NGR A;  4NQK A;  3CL3 A;  2L6A A;  1A1Z A;  3MOP G;  4UZ0 A;  2LWD A;  1DDF A;  4RHW E;  2HM2 Q;  2MPC A;  4M9S A;  4JQW A;  4LWD A;  4N1L A;  2MS8 A;  4F42 A;  3QF2 A;  2VGQ A;  4JUP A;  1WMG A;  3MOP A;  1WXP A;  4P4H A;  2OF5 H;  3J6J A;  2DBD A;  3YGS C;  1E41 A;  1C15 A;  3LQQ A;  4IZ7 B;  2N80 A;  2IB1 A;  1A1W A;  2DBG A;  1ICH A;  1N3K A;  2YGS A;  2N83 A;  2A5Y B;  1YGO A;  4O9F A;  4O6X A;  2BBZ A;  2B1W A;  3KAT A;  4A2W A;  4A2Q A;  3LQR A;  2XV9 A;  1D2Z B;  2LWE A;  4N1J A;  3MOP K;  2O71 A;  4O9L A;  4EWI A;  2YQF A;  2GF5 A;  2NZ7 A;  1PN5 A;  2YU0 A;  1CWW A;  2D96 A;  2MS7 A;  2DO9 A;  1D2Z A;  1DGN A;  2N97 A;  2N00 A;  4I16 A;  4M9X A;  2P1H A;  2KM6 A;  3EZQ A;  4IZA B;  2YVI A;  2BBR A;  4M9Z A;  2DBF A;  3CRD A;  2N1F A;  2NAQ A;  1E3Y A;  4E9M A; 
#chains in the Genus database with same CATH homology
 4RHW A;  4F44 A;  2M5V A;  4IZ5 E;  4N1K A;  2KN6 A;  2G7R A;  4D8O A;  3EZQ B;  2MN4 A;  4QOB A;  3J63 A;  4FH0 A;  4P4H I;  2DBH A;  1WH4 A;  4O7Q A;  3T6P A;  2MJM A;  2LS7 A;  2MB9 A;  1Z6T A;  2OF5 A;  4DWN A;  4ZBW A;  2F1S A;  1UCP A;  2NSN A;  2N7Z A;  1CY5 A;  3YGS P;  1FAD A;  2A9I A;  2L9M A;  1NGR A;  4NQK A;  3CL3 A;  2L6A A;  1A1Z A;  3MOP G;  4UZ0 A;  2LWD A;  1DDF A;  4RHW E;  2HM2 Q;  2MPC A;  4M9S A;  4JQW A;  4LWD A;  4N1L A;  2MS8 A;  4F42 A;  3QF2 A;  2VGQ A;  4JUP A;  1WMG A;  3MOP A;  1WXP A;  4P4H A;  2OF5 H;  3J6J A;  2DBD A;  3YGS C;  1E41 A;  1C15 A;  3LQQ A;  4IZ7 B;  2N80 A;  2IB1 A;  1A1W A;  2DBG A;  1ICH A;  1N3K A;  2YGS A;  2N83 A;  2A5Y B;  1YGO A;  4O9F A;  4O6X A;  2BBZ A;  2B1W A;  3KAT A;  4A2W A;  4A2Q A;  3LQR A;  2XV9 A;  1D2Z B;  2LWE A;  4N1J A;  3MOP K;  2O71 A;  4O9L A;  4EWI A;  2YQF A;  2GF5 A;  2NZ7 A;  1PN5 A;  2YU0 A;  1CWW A;  2D96 A;  2MS7 A;  2DO9 A;  1D2Z A;  1DGN A;  2N97 A;  2N00 A;  4I16 A;  4M9X A;  2P1H A;  2KM6 A;  3EZQ A;  4IZA B;  2YVI A;  2BBR A;  4M9Z A;  2DBF A;  3CRD A;  2N1F A;  2NAQ A;  1E3Y A;  4E9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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