1E3YA

Death domain from human fadd/mort1
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
104
structure length
104
Chain Sequence
GSHMGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title The Three-Dimensional Solution Structure and Dynamic Properties of the Human Fadd Death Domain
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords FADD PROTEIN
total genus 29
structure length 104
sequence length 104
ec nomenclature
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1e3yA00
2N80A 1N3KA 2O71A 2YGSA 4O6XA 1DDFA 3MOPK 2LWEA 1D2ZA 2IB1A 2DO9A 4IZ5E 2NSNA 4QOBA 4JQWA 2B1WA 4RHWA 4A2WA 2GF5A 3EZQB 4N1JA 4M9SA 4O7QA 2MB9A 4DWNA 2BBZA 1NGRA 2DBGA 4O9FA 2N83A 2M5VA 2D96A 2F1SA 4LWDA 2YQFA 3MOPG 1PN5A 4D8OA 1UCPA 2YVIA 2L6AA 1CWWA 3J63A 2A9IA 1CY5A 4P4HA 2KN6A 2LS7A 2N1FA 2MN4A 4P4HI 1A1WA 2KM6A 3YGSP 2A5YB 4RHWE 1A1ZA 2YU0A 4O9LA 4UZ0A 4E9MA 4IZAB 1YGOA 4N1KA 2VGQA 1D2ZB 3KATA 1WMGA 2NZ7A 2HM2Q 2L9MA 4F42A 2N97A 1DGNA 4JUPA 3LQQA 3J6JA 3EZQA 1ICHA 2MS7A 2N7ZA 2P1HA 3MOPA 3YGSC 2DBFA 1E3YA 2DBHA 4ZBWA 4M9ZA 3QF2A 4F44A 3CRDA 2G7RA 1FADA 4N1LA 2N00A 1WXPA 2DBDA 2MPCA 4A2QA 2OF5H 1E41A 2BBRA 4M9XA 2NAQA 1C15A 3T6PA 1Z6TA 4IZ7B 3LQRA 4FH0A 4EWIA 1WH4A 2OF5A 4I16A 4NQKA 2LWDA 3CL3A 2MS8A
chains in the Genus database with same CATH superfamily
2N80A 1N3KA 2O71A 2YGSA 4O6XA 1DDFA 3MOPK 2LWEA 1D2ZA 2IB1A 2DO9A 4IZ5E 2NSNA 2XV9A 4QOBA 4JQWA 2B1WA 4RHWA 4A2WA 2GF5A 3EZQB 4N1JA 4M9SA 4O7QA 2MB9A 4DWNA 2BBZA 1NGRA 2DBGA 4O9FA 2N83A 2M5VA 2D96A 2F1SA 4LWDA 2YQFA 3MOPG 1PN5A 4D8OA 1UCPA 2YVIA 2L6AA 1CWWA 3J63A 2A9IA 1CY5A 4P4HA 2KN6A 2LS7A 2N1FA 2MN4A 4P4HI 1A1WA 2KM6A 3YGSP 2A5YB 4RHWE 1A1ZA 2YU0A 4O9LA 4UZ0A 4E9MA 4IZAB 1YGOA 4N1KA 2VGQA 1D2ZB 3KATA 1WMGA 2NZ7A 2HM2Q 2L9MA 4F42A 2N97A 1DGNA 4JUPA 2MJMA 3LQQA 3J6JA 3EZQA 1ICHA 2MS7A 2N7ZA 2P1HA 3MOPA 3YGSC 2DBFA 1E3YA 2DBHA 4ZBWA 4M9ZA 3QF2A 4F44A 3CRDA 2G7RA 1FADA 4N1LA 2N00A 1WXPA 2DBDA 2MPCA 4A2QA 2OF5H 1E41A 2BBRA 4M9XA 2NAQA 1C15A 3T6PA 1Z6TA 4IZ7B 3LQRA 4FH0A 4EWIA 1WH4A 2OF5A 4I16A 4NQKA 2LWDA 3CL3A 2MS8A
chains in the Genus database with same CATH topology
2N80A 1N3KA 2O71A 2YGSA 4O6XA 1DDFA 3MOPK 2LWEA 1D2ZA 2IB1A 2DO9A 4IZ5E 2NSNA 2XV9A 4QOBA 4JQWA 2B1WA 4RHWA 4A2WA 2GF5A 3EZQB 4N1JA 4M9SA 4O7QA 2MB9A 4DWNA 2BBZA 1NGRA 2DBGA 4O9FA 2N83A 2M5VA 2D96A 2F1SA 4LWDA 2YQFA 3MOPG 1PN5A 4D8OA 1UCPA 2YVIA 2L6AA 1CWWA 3J63A 2A9IA 1CY5A 4P4HA 2KN6A 2LS7A 2N1FA 2MN4A 4P4HI 1A1WA 2KM6A 3YGSP 2A5YB 4RHWE 1A1ZA 2YU0A 4O9LA 4UZ0A 4E9MA 4IZAB 1YGOA 4N1KA 2VGQA 1D2ZB 3KATA 1WMGA 2NZ7A 2HM2Q 2L9MA 4F42A 2N97A 1DGNA 4JUPA 2MJMA 3LQQA 3J6JA 3EZQA 1ICHA 2MS7A 2N7ZA 2P1HA 3MOPA 3YGSC 2DBFA 1E3YA 2DBHA 4ZBWA 4M9ZA 3QF2A 4F44A 3CRDA 2G7RA 1FADA 4N1LA 2N00A 1WXPA 2DBDA 2MPCA 4A2QA 2OF5H 1E41A 2BBRA 4M9XA 2NAQA 1C15A 3T6PA 1Z6TA 4IZ7B 3LQRA 4FH0A 4EWIA 1WH4A 2OF5A 4I16A 4NQKA 2LWDA 3CL3A 2MS8A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2N80 A;  1N3K A;  2O71 A;  2YGS A;  4O6X A;  1DDF A;  3MOP K;  2LWE A;  1D2Z A;  2IB1 A;  2DO9 A;  4IZ5 E;  2NSN A;  4QOB A;  4JQW A;  2B1W A;  4RHW A;  4A2W A;  2GF5 A;  3EZQ B;  4N1J A;  4M9S A;  4O7Q A;  2MB9 A;  4DWN A;  2BBZ A;  1NGR A;  2DBG A;  4O9F A;  2N83 A;  2M5V A;  2D96 A;  2F1S A;  4LWD A;  2YQF A;  3MOP G;  1PN5 A;  4D8O A;  1UCP A;  2YVI A;  2L6A A;  1CWW A;  3J63 A;  2A9I A;  1CY5 A;  4P4H A;  2KN6 A;  2LS7 A;  2N1F A;  2MN4 A;  4P4H I;  1A1W A;  2KM6 A;  3YGS P;  2A5Y B;  4RHW E;  1A1Z A;  2YU0 A;  4O9L A;  4UZ0 A;  4E9M A;  4IZA B;  1YGO A;  4N1K A;  2VGQ A;  1D2Z B;  3KAT A;  1WMG A;  2NZ7 A;  2HM2 Q;  2L9M A;  4F42 A;  2N97 A;  1DGN A;  4JUP A;  3LQQ A;  3J6J A;  3EZQ A;  1ICH A;  2MS7 A;  2N7Z A;  2P1H A;  3MOP A;  3YGS C;  2DBF A;  1E3Y A;  2DBH A;  4ZBW A;  4M9Z A;  3QF2 A;  4F44 A;  3CRD A;  2G7R A;  1FAD A;  4N1L A;  2N00 A;  1WXP A;  2DBD A;  2MPC A;  4A2Q A;  2OF5 H;  1E41 A;  2BBR A;  4M9X A;  2NAQ A;  1C15 A;  3T6P A;  1Z6T A;  4IZ7 B;  3LQR A;  4FH0 A;  4EWI A;  1WH4 A;  2OF5 A;  4I16 A;  4NQK A;  2LWD A;  3CL3 A;  2MS8 A; 
#chains in the Genus database with same CATH topology
 2N80 A;  1N3K A;  2O71 A;  2YGS A;  4O6X A;  1DDF A;  3MOP K;  2LWE A;  1D2Z A;  2IB1 A;  2DO9 A;  4IZ5 E;  2NSN A;  2XV9 A;  4QOB A;  4JQW A;  2B1W A;  4RHW A;  4A2W A;  2GF5 A;  3EZQ B;  4N1J A;  4M9S A;  4O7Q A;  2MB9 A;  4DWN A;  2BBZ A;  1NGR A;  2DBG A;  4O9F A;  2N83 A;  2M5V A;  2D96 A;  2F1S A;  4LWD A;  2YQF A;  3MOP G;  1PN5 A;  4D8O A;  1UCP A;  2YVI A;  2L6A A;  1CWW A;  3J63 A;  2A9I A;  1CY5 A;  4P4H A;  2KN6 A;  2LS7 A;  2N1F A;  2MN4 A;  4P4H I;  1A1W A;  2KM6 A;  3YGS P;  2A5Y B;  4RHW E;  1A1Z A;  2YU0 A;  4O9L A;  4UZ0 A;  4E9M A;  4IZA B;  1YGO A;  4N1K A;  2VGQ A;  1D2Z B;  3KAT A;  1WMG A;  2NZ7 A;  2HM2 Q;  2L9M A;  4F42 A;  2N97 A;  1DGN A;  4JUP A;  2MJM A;  3LQQ A;  3J6J A;  3EZQ A;  1ICH A;  2MS7 A;  2N7Z A;  2P1H A;  3MOP A;  3YGS C;  2DBF A;  1E3Y A;  2DBH A;  4ZBW A;  4M9Z A;  3QF2 A;  4F44 A;  3CRD A;  2G7R A;  1FAD A;  4N1L A;  2N00 A;  1WXP A;  2DBD A;  2MPC A;  4A2Q A;  2OF5 H;  1E41 A;  2BBR A;  4M9X A;  2NAQ A;  1C15 A;  3T6P A;  1Z6T A;  4IZ7 B;  3LQR A;  4FH0 A;  4EWI A;  1WH4 A;  2OF5 A;  4I16 A;  4NQK A;  2LWD A;  3CL3 A;  2MS8 A; 
#chains in the Genus database with same CATH homology
 2N80 A;  1N3K A;  2O71 A;  2YGS A;  4O6X A;  1DDF A;  3MOP K;  2LWE A;  1D2Z A;  2IB1 A;  2DO9 A;  4IZ5 E;  2NSN A;  2XV9 A;  4QOB A;  4JQW A;  2B1W A;  4RHW A;  4A2W A;  2GF5 A;  3EZQ B;  4N1J A;  4M9S A;  4O7Q A;  2MB9 A;  4DWN A;  2BBZ A;  1NGR A;  2DBG A;  4O9F A;  2N83 A;  2M5V A;  2D96 A;  2F1S A;  4LWD A;  2YQF A;  3MOP G;  1PN5 A;  4D8O A;  1UCP A;  2YVI A;  2L6A A;  1CWW A;  3J63 A;  2A9I A;  1CY5 A;  4P4H A;  2KN6 A;  2LS7 A;  2N1F A;  2MN4 A;  4P4H I;  1A1W A;  2KM6 A;  3YGS P;  2A5Y B;  4RHW E;  1A1Z A;  2YU0 A;  4O9L A;  4UZ0 A;  4E9M A;  4IZA B;  1YGO A;  4N1K A;  2VGQ A;  1D2Z B;  3KAT A;  1WMG A;  2NZ7 A;  2HM2 Q;  2L9M A;  4F42 A;  2N97 A;  1DGN A;  4JUP A;  2MJM A;  3LQQ A;  3J6J A;  3EZQ A;  1ICH A;  2MS7 A;  2N7Z A;  2P1H A;  3MOP A;  3YGS C;  2DBF A;  1E3Y A;  2DBH A;  4ZBW A;  4M9Z A;  3QF2 A;  4F44 A;  3CRD A;  2G7R A;  1FAD A;  4N1L A;  2N00 A;  1WXP A;  2DBD A;  2MPC A;  4A2Q A;  2OF5 H;  1E41 A;  2BBR A;  4M9X A;  2NAQ A;  1C15 A;  3T6P A;  1Z6T A;  4IZ7 B;  3LQR A;  4FH0 A;  4EWI A;  1WH4 A;  2OF5 A;  4I16 A;  4NQK A;  2LWD A;  3CL3 A;  2MS8 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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