2MJMA

The solution nmr structure of the nlrc5 caspase recruitment domain (card)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
101
structure length
101
Chain Sequence
GPLGSMDAESIRLNNENLWAWLVRLLSKNPEWLSAKLRSFLPTMDLDCSYEPSNPEVIHRQLNRLFAQGMATWKSFINDLCFELDVPLDMEIPLVSIWGPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase recruitment domain.
pubmed doi rcsb
source organism Mus musculus
molecule tags Signaling protein, protein binding
molecule keywords Protein NLRC5
total genus 33
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2014-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18461 Atypical_Card Atypical caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.20 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2mjmA00
2MJMA
chains in the Genus database with same CATH superfamily
4P4HI 4E9MA 1A1WA 2L6AA 2NZ7A 1DGNA 1N3KA 2OF5A 2HM2Q 4IZ7B 2BBZA 2B1WA 2N83A 4QOBA 1E41A 2DBHA 2N97A 2LWEA 2MS8A 2YQFA 3EZQA 4O6XA 3QF2A 1UCPA 2GF5A 2M5VA 3CL3A 4RHWA 2MB9A 4NQKA 2MS7A 2A5YB 1CY5A 4UZ0A 2P1HA 4M9SA 2YGSA 2MN4A 4LWDA 4I16A 4JUPA 1WXPA 1A1ZA 1NGRA 2LWDA 4N1JA 2DBFA 2KN6A 3MOPK 2XV9A 3EZQB 2A9IA 3MOPA 2YU0A 4A2WA 2KM6A 1FADA 4RHWE 2MPCA 4FH0A 4M9XA 1ICHA 3LQRA 1WMGA 2DBDA 4IZ5E 2N7ZA 1YGOA 3YGSC 1C15A 1E3YA 2D96A 2F1SA 4F42A 2N1FA 4O7QA 2L9MA 2OF5H 2DO9A 2N00A 2O71A 4N1LA 3T6PA 1PN5A 3MOPG 2NSNA 4O9LA 1D2ZB 2MJMA 3KATA 2DBGA 4F44A 4P4HA 4M9ZA 2YVIA 2BBRA 3J6JA 2NAQA 1WH4A 4N1KA 2VGQA 4IZAB 2IB1A 1DDFA 2LS7A 4ZBWA 3YGSP 1Z6TA 3CRDA 2G7RA 4A2QA 2N80A 1D2ZA 4DWNA 4JQWA 4EWIA 4O9FA 3LQQA 4D8OA 3J63A 1CWWA
chains in the Genus database with same CATH topology
4P4HI 4E9MA 1A1WA 2L6AA 2NZ7A 1DGNA 1N3KA 2OF5A 2HM2Q 4IZ7B 2BBZA 2B1WA 2N83A 4QOBA 1E41A 2DBHA 2N97A 2LWEA 2MS8A 2YQFA 3EZQA 4O6XA 3QF2A 1UCPA 2GF5A 2M5VA 3CL3A 4RHWA 2MB9A 4NQKA 2MS7A 2A5YB 1CY5A 4UZ0A 2P1HA 4M9SA 2YGSA 2MN4A 4LWDA 4I16A 4JUPA 1WXPA 1A1ZA 1NGRA 2LWDA 4N1JA 2DBFA 2KN6A 3MOPK 2XV9A 3EZQB 2A9IA 3MOPA 2YU0A 4A2WA 2KM6A 1FADA 4RHWE 2MPCA 4FH0A 4M9XA 1ICHA 3LQRA 1WMGA 2DBDA 4IZ5E 2N7ZA 1YGOA 3YGSC 1C15A 1E3YA 2D96A 2F1SA 4F42A 2N1FA 4O7QA 2L9MA 2OF5H 2DO9A 2N00A 2O71A 4N1LA 3T6PA 1PN5A 3MOPG 2NSNA 4O9LA 1D2ZB 2MJMA 3KATA 2DBGA 4F44A 4P4HA 4M9ZA 2YVIA 2BBRA 3J6JA 2NAQA 1WH4A 4N1KA 2VGQA 4IZAB 2IB1A 1DDFA 2LS7A 4ZBWA 3YGSP 1Z6TA 3CRDA 2G7RA 4A2QA 2N80A 1D2ZA 4DWNA 4JQWA 4EWIA 4O9FA 3LQQA 4D8OA 3J63A 1CWWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MJM A; 
#chains in the Genus database with same CATH topology
 4P4H I;  4E9M A;  1A1W A;  2L6A A;  2NZ7 A;  1DGN A;  1N3K A;  2OF5 A;  2HM2 Q;  4IZ7 B;  2BBZ A;  2B1W A;  2N83 A;  4QOB A;  1E41 A;  2DBH A;  2N97 A;  2LWE A;  2MS8 A;  2YQF A;  3EZQ A;  4O6X A;  3QF2 A;  1UCP A;  2GF5 A;  2M5V A;  3CL3 A;  4RHW A;  2MB9 A;  4NQK A;  2MS7 A;  2A5Y B;  1CY5 A;  4UZ0 A;  2P1H A;  4M9S A;  2YGS A;  2MN4 A;  4LWD A;  4I16 A;  4JUP A;  1WXP A;  1A1Z A;  1NGR A;  2LWD A;  4N1J A;  2DBF A;  2KN6 A;  3MOP K;  2XV9 A;  3EZQ B;  2A9I A;  3MOP A;  2YU0 A;  4A2W A;  2KM6 A;  1FAD A;  4RHW E;  2MPC A;  4FH0 A;  4M9X A;  1ICH A;  3LQR A;  1WMG A;  2DBD A;  4IZ5 E;  2N7Z A;  1YGO A;  3YGS C;  1C15 A;  1E3Y A;  2D96 A;  2F1S A;  4F42 A;  2N1F A;  4O7Q A;  2L9M A;  2OF5 H;  2DO9 A;  2N00 A;  2O71 A;  4N1L A;  3T6P A;  1PN5 A;  3MOP G;  2NSN A;  4O9L A;  1D2Z B;  2MJM A;  3KAT A;  2DBG A;  4F44 A;  4P4H A;  4M9Z A;  2YVI A;  2BBR A;  3J6J A;  2NAQ A;  1WH4 A;  4N1K A;  2VGQ A;  4IZA B;  2IB1 A;  1DDF A;  2LS7 A;  4ZBW A;  3YGS P;  1Z6T A;  3CRD A;  2G7R A;  4A2Q A;  2N80 A;  1D2Z A;  4DWN A;  4JQW A;  4EWI A;  4O9F A;  3LQQ A;  4D8O A;  3J63 A;  1CWW A; 
#chains in the Genus database with same CATH homology
 4P4H I;  4E9M A;  1A1W A;  2L6A A;  2NZ7 A;  1DGN A;  1N3K A;  2OF5 A;  2HM2 Q;  4IZ7 B;  2BBZ A;  2B1W A;  2N83 A;  4QOB A;  1E41 A;  2DBH A;  2N97 A;  2LWE A;  2MS8 A;  2YQF A;  3EZQ A;  4O6X A;  3QF2 A;  1UCP A;  2GF5 A;  2M5V A;  3CL3 A;  4RHW A;  2MB9 A;  4NQK A;  2MS7 A;  2A5Y B;  1CY5 A;  4UZ0 A;  2P1H A;  4M9S A;  2YGS A;  2MN4 A;  4LWD A;  4I16 A;  4JUP A;  1WXP A;  1A1Z A;  1NGR A;  2LWD A;  4N1J A;  2DBF A;  2KN6 A;  3MOP K;  2XV9 A;  3EZQ B;  2A9I A;  3MOP A;  2YU0 A;  4A2W A;  2KM6 A;  1FAD A;  4RHW E;  2MPC A;  4FH0 A;  4M9X A;  1ICH A;  3LQR A;  1WMG A;  2DBD A;  4IZ5 E;  2N7Z A;  1YGO A;  3YGS C;  1C15 A;  1E3Y A;  2D96 A;  2F1S A;  4F42 A;  2N1F A;  4O7Q A;  2L9M A;  2OF5 H;  2DO9 A;  2N00 A;  2O71 A;  4N1L A;  3T6P A;  1PN5 A;  3MOP G;  2NSN A;  4O9L A;  1D2Z B;  2MJM A;  3KAT A;  2DBG A;  4F44 A;  4P4H A;  4M9Z A;  2YVI A;  2BBR A;  3J6J A;  2NAQ A;  1WH4 A;  4N1K A;  2VGQ A;  4IZA B;  2IB1 A;  1DDF A;  2LS7 A;  4ZBW A;  3YGS P;  1Z6T A;  3CRD A;  2G7R A;  4A2Q A;  2N80 A;  1D2Z A;  4DWN A;  4JQW A;  4EWI A;  4O9F A;  3LQQ A;  4D8O A;  3J63 A;  1CWW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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