1E41A

Death domain from human fadd/mort1
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
104
structure length
104
Chain Sequence
GSHMGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title The Three-Dimensional Solution Structure and Dynamic Properties of the Human Fadd Death Domain
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords FADD PROTEIN
total genus 29
structure length 104
sequence length 104
ec nomenclature
pdb deposition date 2000-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1e41A00
1N3KA 2B1WA 2MS7A 2NAQA 1E3YA 2KM6A 4E9MA 3T6PA 2M5VA 2N7ZA 2N00A 2N80A 4JUPA 4DWNA 4P4HI 1A1ZA 4RHWA 1Z6TA 4LWDA 3MOPA 3CRDA 2D96A 2HM2Q 2BBRA 1CY5A 2G7RA 1YGOA 3MOPK 4ZBWA 1WXPA 4IZ5E 3YGSP 4IZ7B 4QOBA 4F44A 4F42A 2NSNA 4JQWA 1DGNA 2YGSA 2MN4A 4O6XA 1A1WA 2YU0A 4A2QA 2DBDA 2N97A 3EZQA 4UZ0A 3QF2A 2MB9A 2MPCA 2NZ7A 1FADA 4D8OA 4M9XA 4N1LA 2DO9A 3YGSC 2OF5A 4P4HA 2YQFA 2DBGA 4N1JA 4IZAB 2KN6A 1DDFA 3CL3A 3EZQB 3LQQA 2N1FA 2GF5A 2IB1A 1WMGA 1D2ZA 1CWWA 3KATA 3MOPG 2MS8A 4EWIA 2A9IA 1E41A 4M9SA 3J6JA 2LWEA 4O7QA 2DBFA 4A2WA 2P1HA 1WH4A 2BBZA 2YVIA 4I16A 2OF5H 2N83A 4M9ZA 2O71A 4N1KA 3J63A 2L6AA 2A5YB 1UCPA 1D2ZB 1ICHA 1NGRA 1C15A 4O9FA 4RHWE 4O9LA 2F1SA 4NQKA 1PN5A 4FH0A 2LWDA 2L9MA 2DBHA 2LS7A 2VGQA 3LQRA
chains in the Genus database with same CATH superfamily
1N3KA 2B1WA 2MS7A 2NAQA 1E3YA 2KM6A 4E9MA 3T6PA 2M5VA 2N7ZA 2N00A 2N80A 4JUPA 2MJMA 4P4HI 4DWNA 1A1ZA 4RHWA 1Z6TA 4LWDA 3MOPA 3CRDA 2D96A 2HM2Q 2BBRA 1CY5A 2G7RA 1YGOA 3MOPK 4ZBWA 2XV9A 1WXPA 4IZ5E 3YGSP 4IZ7B 4QOBA 4F44A 4F42A 2NSNA 4JQWA 1DGNA 2YGSA 2MN4A 4O6XA 1A1WA 2YU0A 4A2QA 2DBDA 2N97A 3EZQA 4UZ0A 3QF2A 2MB9A 2MPCA 2NZ7A 1FADA 4D8OA 4M9XA 4N1LA 2DO9A 3YGSC 2OF5A 4P4HA 2YQFA 2DBGA 4N1JA 4IZAB 2KN6A 1DDFA 3CL3A 3EZQB 3LQQA 2N1FA 2GF5A 2IB1A 1WMGA 1D2ZA 1CWWA 3KATA 3MOPG 2MS8A 4EWIA 2A9IA 1E41A 4M9SA 3J6JA 2LWEA 4O7QA 2DBFA 4A2WA 2P1HA 1WH4A 2BBZA 2YVIA 4I16A 2OF5H 2N83A 4M9ZA 2O71A 4N1KA 3J63A 2L6AA 2A5YB 1UCPA 1D2ZB 1ICHA 1NGRA 1C15A 4O9FA 4RHWE 4O9LA 2F1SA 4NQKA 1PN5A 4FH0A 2LWDA 2L9MA 2DBHA 2LS7A 2VGQA 3LQRA
chains in the Genus database with same CATH topology
1N3KA 2B1WA 2MS7A 2NAQA 1E3YA 2KM6A 4E9MA 3T6PA 2M5VA 2N7ZA 2N00A 2N80A 4JUPA 2MJMA 4P4HI 4DWNA 1A1ZA 4RHWA 1Z6TA 4LWDA 3MOPA 3CRDA 2D96A 2HM2Q 2BBRA 1CY5A 2G7RA 1YGOA 3MOPK 4ZBWA 2XV9A 1WXPA 4IZ5E 3YGSP 4IZ7B 4QOBA 4F44A 4F42A 2NSNA 4JQWA 1DGNA 2YGSA 2MN4A 4O6XA 1A1WA 2YU0A 4A2QA 2DBDA 2N97A 3EZQA 4UZ0A 3QF2A 2MB9A 2MPCA 2NZ7A 1FADA 4D8OA 4M9XA 4N1LA 2DO9A 3YGSC 2OF5A 4P4HA 2YQFA 2DBGA 4N1JA 4IZAB 2KN6A 1DDFA 3CL3A 3EZQB 3LQQA 2N1FA 2GF5A 2IB1A 1WMGA 1D2ZA 1CWWA 3KATA 3MOPG 2MS8A 4EWIA 2A9IA 1E41A 4M9SA 3J6JA 2LWEA 4O7QA 2DBFA 4A2WA 2P1HA 1WH4A 2BBZA 2YVIA 4I16A 2OF5H 2N83A 4M9ZA 2O71A 4N1KA 3J63A 2L6AA 2A5YB 1UCPA 1D2ZB 1ICHA 1NGRA 1C15A 4O9FA 4RHWE 4O9LA 2F1SA 4NQKA 1PN5A 4FH0A 2LWDA 2L9MA 2DBHA 2LS7A 2VGQA 3LQRA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1N3K A;  2B1W A;  2MS7 A;  2NAQ A;  1E3Y A;  2KM6 A;  4E9M A;  3T6P A;  2M5V A;  2N7Z A;  2N00 A;  2N80 A;  4JUP A;  4DWN A;  4P4H I;  1A1Z A;  4RHW A;  1Z6T A;  4LWD A;  3MOP A;  3CRD A;  2D96 A;  2HM2 Q;  2BBR A;  1CY5 A;  2G7R A;  1YGO A;  3MOP K;  4ZBW A;  1WXP A;  4IZ5 E;  3YGS P;  4IZ7 B;  4QOB A;  4F44 A;  4F42 A;  2NSN A;  4JQW A;  1DGN A;  2YGS A;  2MN4 A;  4O6X A;  1A1W A;  2YU0 A;  4A2Q A;  2DBD A;  2N97 A;  3EZQ A;  4UZ0 A;  3QF2 A;  2MB9 A;  2MPC A;  2NZ7 A;  1FAD A;  4D8O A;  4M9X A;  4N1L A;  2DO9 A;  3YGS C;  2OF5 A;  4P4H A;  2YQF A;  2DBG A;  4N1J A;  4IZA B;  2KN6 A;  1DDF A;  3CL3 A;  3EZQ B;  3LQQ A;  2N1F A;  2GF5 A;  2IB1 A;  1WMG A;  1D2Z A;  1CWW A;  3KAT A;  3MOP G;  2MS8 A;  4EWI A;  2A9I A;  1E41 A;  4M9S A;  3J6J A;  2LWE A;  4O7Q A;  2DBF A;  4A2W A;  2P1H A;  1WH4 A;  2BBZ A;  2YVI A;  4I16 A;  2OF5 H;  2N83 A;  4M9Z A;  2O71 A;  4N1K A;  3J63 A;  2L6A A;  2A5Y B;  1UCP A;  1D2Z B;  1ICH A;  1NGR A;  1C15 A;  4O9F A;  4RHW E;  4O9L A;  2F1S A;  4NQK A;  1PN5 A;  4FH0 A;  2LWD A;  2L9M A;  2DBH A;  2LS7 A;  2VGQ A;  3LQR A; 
#chains in the Genus database with same CATH topology
 1N3K A;  2B1W A;  2MS7 A;  2NAQ A;  1E3Y A;  2KM6 A;  4E9M A;  3T6P A;  2M5V A;  2N7Z A;  2N00 A;  2N80 A;  4JUP A;  2MJM A;  4P4H I;  4DWN A;  1A1Z A;  4RHW A;  1Z6T A;  4LWD A;  3MOP A;  3CRD A;  2D96 A;  2HM2 Q;  2BBR A;  1CY5 A;  2G7R A;  1YGO A;  3MOP K;  4ZBW A;  2XV9 A;  1WXP A;  4IZ5 E;  3YGS P;  4IZ7 B;  4QOB A;  4F44 A;  4F42 A;  2NSN A;  4JQW A;  1DGN A;  2YGS A;  2MN4 A;  4O6X A;  1A1W A;  2YU0 A;  4A2Q A;  2DBD A;  2N97 A;  3EZQ A;  4UZ0 A;  3QF2 A;  2MB9 A;  2MPC A;  2NZ7 A;  1FAD A;  4D8O A;  4M9X A;  4N1L A;  2DO9 A;  3YGS C;  2OF5 A;  4P4H A;  2YQF A;  2DBG A;  4N1J A;  4IZA B;  2KN6 A;  1DDF A;  3CL3 A;  3EZQ B;  3LQQ A;  2N1F A;  2GF5 A;  2IB1 A;  1WMG A;  1D2Z A;  1CWW A;  3KAT A;  3MOP G;  2MS8 A;  4EWI A;  2A9I A;  1E41 A;  4M9S A;  3J6J A;  2LWE A;  4O7Q A;  2DBF A;  4A2W A;  2P1H A;  1WH4 A;  2BBZ A;  2YVI A;  4I16 A;  2OF5 H;  2N83 A;  4M9Z A;  2O71 A;  4N1K A;  3J63 A;  2L6A A;  2A5Y B;  1UCP A;  1D2Z B;  1ICH A;  1NGR A;  1C15 A;  4O9F A;  4RHW E;  4O9L A;  2F1S A;  4NQK A;  1PN5 A;  4FH0 A;  2LWD A;  2L9M A;  2DBH A;  2LS7 A;  2VGQ A;  3LQR A; 
#chains in the Genus database with same CATH homology
 1N3K A;  2B1W A;  2MS7 A;  2NAQ A;  1E3Y A;  2KM6 A;  4E9M A;  3T6P A;  2M5V A;  2N7Z A;  2N00 A;  2N80 A;  4JUP A;  2MJM A;  4P4H I;  4DWN A;  1A1Z A;  4RHW A;  1Z6T A;  4LWD A;  3MOP A;  3CRD A;  2D96 A;  2HM2 Q;  2BBR A;  1CY5 A;  2G7R A;  1YGO A;  3MOP K;  4ZBW A;  2XV9 A;  1WXP A;  4IZ5 E;  3YGS P;  4IZ7 B;  4QOB A;  4F44 A;  4F42 A;  2NSN A;  4JQW A;  1DGN A;  2YGS A;  2MN4 A;  4O6X A;  1A1W A;  2YU0 A;  4A2Q A;  2DBD A;  2N97 A;  3EZQ A;  4UZ0 A;  3QF2 A;  2MB9 A;  2MPC A;  2NZ7 A;  1FAD A;  4D8O A;  4M9X A;  4N1L A;  2DO9 A;  3YGS C;  2OF5 A;  4P4H A;  2YQF A;  2DBG A;  4N1J A;  4IZA B;  2KN6 A;  1DDF A;  3CL3 A;  3EZQ B;  3LQQ A;  2N1F A;  2GF5 A;  2IB1 A;  1WMG A;  1D2Z A;  1CWW A;  3KAT A;  3MOP G;  2MS8 A;  4EWI A;  2A9I A;  1E41 A;  4M9S A;  3J6J A;  2LWE A;  4O7Q A;  2DBF A;  4A2W A;  2P1H A;  1WH4 A;  2BBZ A;  2YVI A;  4I16 A;  2OF5 H;  2N83 A;  4M9Z A;  2O71 A;  4N1K A;  3J63 A;  2L6A A;  2A5Y B;  1UCP A;  1D2Z B;  1ICH A;  1NGR A;  1C15 A;  4O9F A;  4RHW E;  4O9L A;  2F1S A;  4NQK A;  1PN5 A;  4FH0 A;  2LWD A;  2L9M A;  2DBH A;  2LS7 A;  2VGQ A;  3LQR A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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