1PN5 | Genus

Total Genus 23

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	23
sequence length	93
structure length	93
Chain Sequence	MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Apoptosis
source organism	Homo sapiens
publication title	NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain pubmed doi rcsb
molecule keywords	NACHT-, LRR- and PYD-containing protein 2
total genus	23
structure length	93
sequence length	93
ec nomenclature
pdb deposition date	2003-06-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01378	IgG_binding_B	B domain
A	PF02758	PYRIN	PAAD/DAPIN/Pyrin domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.533.10	Mainly Alpha	Orthogonal Bundle	Death Domain, Fas	Death Domain, Fas	1pn5A00

2MPCA 4M9ZA 1ICHA 2NZ7A 2N80A 2DBDA 2F1SA 4JUPA 4F42A 4JQWA 4D8OA 1NGRA 2N00A 4DWNA 2LWDA 1WMGA 1DGNA 1D2ZA 2YU0A 2O71A 3MOPA 1C15A 2N1FA 1WH4A 3CRDA 2BBZA 1CY5A 2D96A 3T6PA 4O9LA 2KN6A 4N1KA 4N1JA 3J6JA 2LWEA 3EZQA 2OF5A 4IZ7B 2N83A 1DDFA 2LS7A 4IZAB 4RHWE 4O7QA 2YVIA 1D2ZB 2B1WA 2DO9A 2N97A 2A9IA 4QOBA 4O6XA 3QF2A 1CWWA 2DBFA 2N7ZA 3J63A 2MN4A 1PN5A 3CL3A 4P4HA 2KM6A 2IB1A 1E41A 2M5VA 2YGSA 3EZQB 4UZ0A 1FADA 3LQRA 4F44A 1UCPA 2DBHA 2GF5A 4M9XA 2NAQA 4O9FA 2NSNA 2YQFA 1A1ZA 4I16A 3MOPG 2HM2Q 2DBGA 2L9MA 2A5YB 2MS8A 3MOPK 4IZ5E 1YGOA 4M9SA 2OF5H 4A2QA 4RHWA 2BBRA 1A1WA 3YGSC 2MB9A 4N1LA 1Z6TA 3YGSP 2VGQA 1E3YA 4FH0A 4E9MA 2MS7A 2L6AA 4NQKA 4ZBWA 1N3KA 4P4HI 2P1HA 2G7RA 3LQQA 4LWDA 4EWIA 4A2WA 3KATA 1WXPA
chains in the Genus database with same CATH superfamily

2MPCA 4M9ZA 1ICHA 2NZ7A 2N80A 2DBDA 2F1SA 4JUPA 4F42A 4JQWA 4D8OA 1NGRA 2N00A 4DWNA 2LWDA 1WMGA 1DGNA 1D2ZA 2YU0A 2O71A 3MOPA 1C15A 2N1FA 1WH4A 3CRDA 2BBZA 2MJMA 1CY5A 2D96A 3T6PA 4O9LA 2KN6A 4N1KA 4N1JA 3J6JA 2LWEA 3EZQA 2OF5A 4IZ7B 2N83A 1DDFA 2LS7A 4IZAB 4RHWE 4O7QA 2YVIA 1D2ZB 2B1WA 2DO9A 2N97A 2A9IA 4QOBA 4O6XA 3QF2A 1CWWA 2DBFA 2N7ZA 3J63A 2MN4A 1PN5A 3CL3A 4P4HA 2KM6A 2IB1A 1E41A 2M5VA 2YGSA 3EZQB 4UZ0A 1FADA 3LQRA 4F44A 1UCPA 2DBHA 2GF5A 4M9XA 2NAQA 4O9FA 2NSNA 2YQFA 1A1ZA 4I16A 3MOPG 2HM2Q 2DBGA 2L9MA 2A5YB 2MS8A 3MOPK 4IZ5E 1YGOA 4M9SA 2OF5H 4A2QA 2XV9A 4RHWA 2BBRA 1A1WA 3YGSC 2MB9A 4N1LA 1Z6TA 3YGSP 2VGQA 1E3YA 4FH0A 4E9MA 2MS7A 2L6AA 4NQKA 4ZBWA 1N3KA 4P4HI 2P1HA 2G7RA 3LQQA 4LWDA 4EWIA 4A2WA 3KATA 1WXPA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2MPC A;  4M9Z A;  1ICH A;  2NZ7 A;  2N80 A;  2DBD A;  2F1S A;  4JUP A;  4F42 A;  4JQW A;  4D8O A;  1NGR A;  2N00 A;  4DWN A;  2LWD A;  1WMG A;  1DGN A;  1D2Z A;  2YU0 A;  2O71 A;  3MOP A;  1C15 A;  2N1F A;  1WH4 A;  3CRD A;  2BBZ A;  1CY5 A;  2D96 A;  3T6P A;  4O9L A;  2KN6 A;  4N1K A;  4N1J A;  3J6J A;  2LWE A;  3EZQ A;  2OF5 A;  4IZ7 B;  2N83 A;  1DDF A;  2LS7 A;  4IZA B;  4RHW E;  4O7Q A;  2YVI A;  1D2Z B;  2B1W A;  2DO9 A;  2N97 A;  2A9I A;  4QOB A;  4O6X A;  3QF2 A;  1CWW A;  2DBF A;  2N7Z A;  3J63 A;  2MN4 A;  1PN5 A;  3CL3 A;  4P4H A;  2KM6 A;  2IB1 A;  1E41 A;  2M5V A;  2YGS A;  3EZQ B;  4UZ0 A;  1FAD A;  3LQR A;  4F44 A;  1UCP A;  2DBH A;  2GF5 A;  4M9X A;  2NAQ A;  4O9F A;  2NSN A;  2YQF A;  1A1Z A;  4I16 A;  3MOP G;  2HM2 Q;  2DBG A;  2L9M A;  2A5Y B;  2MS8 A;  3MOP K;  4IZ5 E;  1YGO A;  4M9S A;  2OF5 H;  4A2Q A;  4RHW A;  2BBR A;  1A1W A;  3YGS C;  2MB9 A;  4N1L A;  1Z6T A;  3YGS P;  2VGQ A;  1E3Y A;  4FH0 A;  4E9M A;  2MS7 A;  2L6A A;  4NQK A;  4ZBW A;  1N3K A;  4P4H I;  2P1H A;  2G7R A;  3LQQ A;  4LWD A;  4EWI A;  4A2W A;  3KAT A;  1WXP A; 
#chains in the Genus database with same CATH topology
 2MPC A;  4M9Z A;  1ICH A;  2NZ7 A;  2N80 A;  2DBD A;  2F1S A;  4JUP A;  4F42 A;  4JQW A;  4D8O A;  1NGR A;  2N00 A;  4DWN A;  2LWD A;  1WMG A;  1DGN A;  1D2Z A;  2YU0 A;  2O71 A;  3MOP A;  1C15 A;  2N1F A;  1WH4 A;  3CRD A;  2BBZ A;  2MJM A;  1CY5 A;  2D96 A;  3T6P A;  4O9L A;  2KN6 A;  4N1K A;  4N1J A;  3J6J A;  2LWE A;  3EZQ A;  2OF5 A;  4IZ7 B;  2N83 A;  1DDF A;  2LS7 A;  4IZA B;  4RHW E;  4O7Q A;  2YVI A;  1D2Z B;  2B1W A;  2DO9 A;  2N97 A;  2A9I A;  4QOB A;  4O6X A;  3QF2 A;  1CWW A;  2DBF A;  2N7Z A;  3J63 A;  2MN4 A;  1PN5 A;  3CL3 A;  4P4H A;  2KM6 A;  2IB1 A;  1E41 A;  2M5V A;  2YGS A;  3EZQ B;  4UZ0 A;  1FAD A;  3LQR A;  4F44 A;  1UCP A;  2DBH A;  2GF5 A;  4M9X A;  2NAQ A;  4O9F A;  2NSN A;  2YQF A;  1A1Z A;  4I16 A;  3MOP G;  2HM2 Q;  2DBG A;  2L9M A;  2A5Y B;  2MS8 A;  3MOP K;  4IZ5 E;  1YGO A;  4M9S A;  2OF5 H;  4A2Q A;  2XV9 A;  4RHW A;  2BBR A;  1A1W A;  3YGS C;  2MB9 A;  4N1L A;  1Z6T A;  3YGS P;  2VGQ A;  1E3Y A;  4FH0 A;  4E9M A;  2MS7 A;  2L6A A;  4NQK A;  4ZBW A;  1N3K A;  4P4H I;  2P1H A;  2G7R A;  3LQQ A;  4LWD A;  4EWI A;  4A2W A;  3KAT A;  1WXP A; 
#chains in the Genus database with same CATH homology
 2MPC A;  4M9Z A;  1ICH A;  2NZ7 A;  2N80 A;  2DBD A;  2F1S A;  4JUP A;  4F42 A;  4JQW A;  4D8O A;  1NGR A;  2N00 A;  4DWN A;  2LWD A;  1WMG A;  1DGN A;  1D2Z A;  2YU0 A;  2O71 A;  3MOP A;  1C15 A;  2N1F A;  1WH4 A;  3CRD A;  2BBZ A;  2MJM A;  1CY5 A;  2D96 A;  3T6P A;  4O9L A;  2KN6 A;  4N1K A;  4N1J A;  3J6J A;  2LWE A;  3EZQ A;  2OF5 A;  4IZ7 B;  2N83 A;  1DDF A;  2LS7 A;  4IZA B;  4RHW E;  4O7Q A;  2YVI A;  1D2Z B;  2B1W A;  2DO9 A;  2N97 A;  2A9I A;  4QOB A;  4O6X A;  3QF2 A;  1CWW A;  2DBF A;  2N7Z A;  3J63 A;  2MN4 A;  1PN5 A;  3CL3 A;  4P4H A;  2KM6 A;  2IB1 A;  1E41 A;  2M5V A;  2YGS A;  3EZQ B;  4UZ0 A;  1FAD A;  3LQR A;  4F44 A;  1UCP A;  2DBH A;  2GF5 A;  4M9X A;  2NAQ A;  4O9F A;  2NSN A;  2YQF A;  1A1Z A;  4I16 A;  3MOP G;  2HM2 Q;  2DBG A;  2L9M A;  2A5Y B;  2MS8 A;  3MOP K;  4IZ5 E;  1YGO A;  4M9S A;  2OF5 H;  4A2Q A;  2XV9 A;  4RHW A;  2BBR A;  1A1W A;  3YGS C;  2MB9 A;  4N1L A;  1Z6T A;  3YGS P;  2VGQ A;  1E3Y A;  4FH0 A;  4E9M A;  2MS7 A;  2L6A A;  4NQK A;  4ZBW A;  1N3K A;  4P4H I;  2P1H A;  2G7R A;  3LQQ A;  4LWD A;  4EWI A;  4A2W A;  3KAT A;  1WXP A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1PN5A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations