1UCPA

Nmr structure of the pyrin domain of human asc
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
91
structure length
91
Chain Sequence
MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTANVLRDMGLQEMAGQLQAATHQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis-associated speck-like protein containing a CARD
total genus 28
structure length 91
sequence length 91
ec nomenclature
pdb deposition date 2003-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02758 PYRIN PAAD/DAPIN/Pyrin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1ucpA00
2OF5H 4JQWA 1E3YA 1A1WA 1NGRA 2P1HA 4A2WA 4ZBWA 3KATA 3QF2A 3LQRA 1A1ZA 4N1JA 4O9FA 4RHWE 3CRDA 3J63A 2NSNA 1PN5A 1WH4A 4NQKA 1DDFA 1D2ZB 1UCPA 4M9SA 3J6JA 3EZQB 4P4HI 3MOPK 4RHWA 2DO9A 1C15A 1WMGA 2IB1A 2KM6A 2LWDA 3YGSC 2DBHA 2G7RA 2LWEA 2NZ7A 2BBRA 2HM2Q 4DWNA 2LS7A 2YQFA 2BBZA 4O6XA 4P4HA 1YGOA 2VGQA 3LQQA 4UZ0A 1Z6TA 2NAQA 1CY5A 2N97A 4O7QA 4EWIA 4F42A 2DBGA 4E9MA 4I16A 2GF5A 2YGSA 4N1KA 2YU0A 4IZAB 2D96A 3EZQA 4FH0A 3MOPA 4LWDA 2A5YB 2MPCA 4QOBA 2DBDA 2L9MA 4D8OA 4A2QA 2N80A 2O71A 3T6PA 2OF5A 2F1SA 1WXPA 2YVIA 1N3KA 4F44A 2MN4A 2MB9A 2B1WA 1DGNA 3YGSP 2N7ZA 2A9IA 1E41A 2N83A 2N00A 2L6AA 3MOPG 4JUPA 4M9ZA 1ICHA 4IZ7B 2N1FA 2MS8A 1FADA 2MS7A 1CWWA 1D2ZA 4IZ5E 3CL3A 2DBFA 4O9LA 4N1LA 4M9XA 2KN6A 2M5VA
chains in the Genus database with same CATH superfamily
2XV9A 2OF5H 4JQWA 1E3YA 1A1WA 1NGRA 2P1HA 4A2WA 4ZBWA 3KATA 3QF2A 3LQRA 1A1ZA 4N1JA 4O9FA 4RHWE 3CRDA 3J63A 2NSNA 1PN5A 1WH4A 4NQKA 1DDFA 1D2ZB 1UCPA 4M9SA 3J6JA 3EZQB 4P4HI 3MOPK 4RHWA 2DO9A 1C15A 1WMGA 2IB1A 2KM6A 2LWDA 3YGSC 2DBHA 2G7RA 2LWEA 2NZ7A 2BBRA 2HM2Q 4DWNA 2LS7A 2YQFA 2BBZA 4O6XA 4P4HA 1YGOA 2VGQA 3LQQA 4UZ0A 2MJMA 1Z6TA 2NAQA 1CY5A 2N97A 4O7QA 4EWIA 4F42A 2DBGA 4E9MA 4I16A 2GF5A 2YGSA 4N1KA 2YU0A 4IZAB 2D96A 3EZQA 4FH0A 3MOPA 4LWDA 2A5YB 2MPCA 4QOBA 2DBDA 2L9MA 4D8OA 4A2QA 2N80A 2O71A 3T6PA 2OF5A 2F1SA 1WXPA 2YVIA 1N3KA 4F44A 2MN4A 2MB9A 2B1WA 1DGNA 3YGSP 2N7ZA 2A9IA 1E41A 2N83A 2N00A 2L6AA 3MOPG 4JUPA 4M9ZA 1ICHA 4IZ7B 2N1FA 2MS8A 1FADA 2MS7A 1CWWA 1D2ZA 4IZ5E 3CL3A 2DBFA 4O9LA 4N1LA 4M9XA 2KN6A 2M5VA
chains in the Genus database with same CATH topology
2XV9A 2OF5H 4JQWA 1E3YA 1A1WA 1NGRA 2P1HA 4A2WA 4ZBWA 3KATA 3QF2A 3LQRA 1A1ZA 4N1JA 4O9FA 4RHWE 3CRDA 3J63A 2NSNA 1PN5A 1WH4A 4NQKA 1DDFA 1D2ZB 1UCPA 4M9SA 3J6JA 3EZQB 4P4HI 3MOPK 4RHWA 2DO9A 1C15A 1WMGA 2IB1A 2KM6A 2LWDA 3YGSC 2DBHA 2G7RA 2LWEA 2NZ7A 2BBRA 2HM2Q 4DWNA 2LS7A 2YQFA 2BBZA 4O6XA 4P4HA 1YGOA 2VGQA 3LQQA 4UZ0A 2MJMA 1Z6TA 2NAQA 1CY5A 2N97A 4O7QA 4EWIA 4F42A 2DBGA 4E9MA 4I16A 2GF5A 2YGSA 4N1KA 2YU0A 4IZAB 2D96A 3EZQA 4FH0A 3MOPA 4LWDA 2A5YB 2MPCA 4QOBA 2DBDA 2L9MA 4D8OA 4A2QA 2N80A 2O71A 3T6PA 2OF5A 2F1SA 1WXPA 2YVIA 1N3KA 4F44A 2MN4A 2MB9A 2B1WA 1DGNA 3YGSP 2N7ZA 2A9IA 1E41A 2N83A 2N00A 2L6AA 3MOPG 4JUPA 4M9ZA 1ICHA 4IZ7B 2N1FA 2MS8A 1FADA 2MS7A 1CWWA 1D2ZA 4IZ5E 3CL3A 2DBFA 4O9LA 4N1LA 4M9XA 2KN6A 2M5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OF5 H;  4JQW A;  1E3Y A;  1A1W A;  1NGR A;  2P1H A;  4A2W A;  4ZBW A;  3KAT A;  3QF2 A;  3LQR A;  1A1Z A;  4N1J A;  4O9F A;  4RHW E;  3CRD A;  3J63 A;  2NSN A;  1PN5 A;  1WH4 A;  4NQK A;  1DDF A;  1D2Z B;  1UCP A;  4M9S A;  3J6J A;  3EZQ B;  4P4H I;  3MOP K;  4RHW A;  2DO9 A;  1C15 A;  1WMG A;  2IB1 A;  2KM6 A;  2LWD A;  3YGS C;  2DBH A;  2G7R A;  2LWE A;  2NZ7 A;  2BBR A;  2HM2 Q;  4DWN A;  2LS7 A;  2YQF A;  2BBZ A;  4O6X A;  4P4H A;  1YGO A;  2VGQ A;  3LQQ A;  4UZ0 A;  1Z6T A;  2NAQ A;  1CY5 A;  2N97 A;  4O7Q A;  4EWI A;  4F42 A;  2DBG A;  4E9M A;  4I16 A;  2GF5 A;  2YGS A;  4N1K A;  2YU0 A;  4IZA B;  2D96 A;  3EZQ A;  4FH0 A;  3MOP A;  4LWD A;  2A5Y B;  2MPC A;  4QOB A;  2DBD A;  2L9M A;  4D8O A;  4A2Q A;  2N80 A;  2O71 A;  3T6P A;  2OF5 A;  2F1S A;  1WXP A;  2YVI A;  1N3K A;  4F44 A;  2MN4 A;  2MB9 A;  2B1W A;  1DGN A;  3YGS P;  2N7Z A;  2A9I A;  1E41 A;  2N83 A;  2N00 A;  2L6A A;  3MOP G;  4JUP A;  4M9Z A;  1ICH A;  4IZ7 B;  2N1F A;  2MS8 A;  1FAD A;  2MS7 A;  1CWW A;  1D2Z A;  4IZ5 E;  3CL3 A;  2DBF A;  4O9L A;  4N1L A;  4M9X A;  2KN6 A;  2M5V A; 
#chains in the Genus database with same CATH topology
 2XV9 A;  2OF5 H;  4JQW A;  1E3Y A;  1A1W A;  1NGR A;  2P1H A;  4A2W A;  4ZBW A;  3KAT A;  3QF2 A;  3LQR A;  1A1Z A;  4N1J A;  4O9F A;  4RHW E;  3CRD A;  3J63 A;  2NSN A;  1PN5 A;  1WH4 A;  4NQK A;  1DDF A;  1D2Z B;  1UCP A;  4M9S A;  3J6J A;  3EZQ B;  4P4H I;  3MOP K;  4RHW A;  2DO9 A;  1C15 A;  1WMG A;  2IB1 A;  2KM6 A;  2LWD A;  3YGS C;  2DBH A;  2G7R A;  2LWE A;  2NZ7 A;  2BBR A;  2HM2 Q;  4DWN A;  2LS7 A;  2YQF A;  2BBZ A;  4O6X A;  4P4H A;  1YGO A;  2VGQ A;  3LQQ A;  4UZ0 A;  2MJM A;  1Z6T A;  2NAQ A;  1CY5 A;  2N97 A;  4O7Q A;  4EWI A;  4F42 A;  2DBG A;  4E9M A;  4I16 A;  2GF5 A;  2YGS A;  4N1K A;  2YU0 A;  4IZA B;  2D96 A;  3EZQ A;  4FH0 A;  3MOP A;  4LWD A;  2A5Y B;  2MPC A;  4QOB A;  2DBD A;  2L9M A;  4D8O A;  4A2Q A;  2N80 A;  2O71 A;  3T6P A;  2OF5 A;  2F1S A;  1WXP A;  2YVI A;  1N3K A;  4F44 A;  2MN4 A;  2MB9 A;  2B1W A;  1DGN A;  3YGS P;  2N7Z A;  2A9I A;  1E41 A;  2N83 A;  2N00 A;  2L6A A;  3MOP G;  4JUP A;  4M9Z A;  1ICH A;  4IZ7 B;  2N1F A;  2MS8 A;  1FAD A;  2MS7 A;  1CWW A;  1D2Z A;  4IZ5 E;  3CL3 A;  2DBF A;  4O9L A;  4N1L A;  4M9X A;  2KN6 A;  2M5V A; 
#chains in the Genus database with same CATH homology
 2XV9 A;  2OF5 H;  4JQW A;  1E3Y A;  1A1W A;  1NGR A;  2P1H A;  4A2W A;  4ZBW A;  3KAT A;  3QF2 A;  3LQR A;  1A1Z A;  4N1J A;  4O9F A;  4RHW E;  3CRD A;  3J63 A;  2NSN A;  1PN5 A;  1WH4 A;  4NQK A;  1DDF A;  1D2Z B;  1UCP A;  4M9S A;  3J6J A;  3EZQ B;  4P4H I;  3MOP K;  4RHW A;  2DO9 A;  1C15 A;  1WMG A;  2IB1 A;  2KM6 A;  2LWD A;  3YGS C;  2DBH A;  2G7R A;  2LWE A;  2NZ7 A;  2BBR A;  2HM2 Q;  4DWN A;  2LS7 A;  2YQF A;  2BBZ A;  4O6X A;  4P4H A;  1YGO A;  2VGQ A;  3LQQ A;  4UZ0 A;  2MJM A;  1Z6T A;  2NAQ A;  1CY5 A;  2N97 A;  4O7Q A;  4EWI A;  4F42 A;  2DBG A;  4E9M A;  4I16 A;  2GF5 A;  2YGS A;  4N1K A;  2YU0 A;  4IZA B;  2D96 A;  3EZQ A;  4FH0 A;  3MOP A;  4LWD A;  2A5Y B;  2MPC A;  4QOB A;  2DBD A;  2L9M A;  4D8O A;  4A2Q A;  2N80 A;  2O71 A;  3T6P A;  2OF5 A;  2F1S A;  1WXP A;  2YVI A;  1N3K A;  4F44 A;  2MN4 A;  2MB9 A;  2B1W A;  1DGN A;  3YGS P;  2N7Z A;  2A9I A;  1E41 A;  2N83 A;  2N00 A;  2L6A A;  3MOP G;  4JUP A;  4M9Z A;  1ICH A;  4IZ7 B;  2N1F A;  2MS8 A;  1FAD A;  2MS7 A;  1CWW A;  1D2Z A;  4IZ5 E;  3CL3 A;  2DBF A;  4O9L A;  4N1L A;  4M9X A;  2KN6 A;  2M5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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