2A9I | Genus

Total Genus 34

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	34
sequence length	105
structure length	105
Chain Sequence	KPLTPSTYIRNLNVGILRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGLSPTCELLFDWGTTNCTVGDLVDLLVQIELFAPATLLLPDAVPQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 105 atoms

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105 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Mus musculus
publication title	Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling. pubmed rcsb
molecule keywords	Interleukin-1 receptor-associated kinase-4
total genus	34
structure length	105
sequence length	105
ec nomenclature	ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date	2005-07-11

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.533.10	Mainly Alpha	Orthogonal Bundle	Death Domain, Fas	Death Domain, Fas	2a9iA00

2NAQA 2D96A 1A1WA 2F1SA 2BBRA 2NZ7A 2HM2Q 2KN6A 1N3KA 4QOBA 4N1KA 1CWWA 3EZQB 4N1LA 3YGSP 4UZ0A 2OF5A 3EZQA 3T6PA 2OF5H 1WXPA 3MOPK 3LQRA 4N1JA 3QF2A 2LWEA 4D8OA 2MPCA 4A2QA 4IZ7B 1C15A 1A1ZA 2A5YB 2KM6A 3MOPG 4M9ZA 3KATA 2N00A 4M9XA 1D2ZB 2A9IA 1E3YA 2N97A 3J63A 1WMGA 1D2ZA 4EWIA 4P4HI 3MOPA 2LS7A 1YGOA 2VGQA 4IZ5E 1NGRA 1WH4A 2P1HA 4IZAB 4P4HA 1E41A 1DDFA 3LQQA 4F42A 2N1FA 2O71A 4O9FA 4NQKA 2MB9A 2L6AA 1PN5A 2MS8A 2DBGA 2NSNA 2BBZA 2DBFA 3CL3A 4RHWE 4O7QA 4M9SA 4O9LA 4RHWA 1DGNA 2IB1A 1ICHA 2YQFA 3YGSC 3J6JA 2MN4A 4DWNA 2YVIA 2MS7A 2N83A 2YGSA 2B1WA 2G7RA 4JUPA 4E9MA 2YU0A 2N80A 1CY5A 4ZBWA 1UCPA 2DO9A 4LWDA 2L9MA 1Z6TA 2GF5A 4JQWA 4O6XA 2LWDA 4F44A 2DBDA 2N7ZA 4A2WA 2DBHA 2M5VA 3CRDA 1FADA 4I16A 4FH0A
chains in the Genus database with same CATH superfamily

2NAQA 2D96A 1A1WA 2F1SA 2BBRA 2NZ7A 2HM2Q 2KN6A 1N3KA 4QOBA 4N1KA 1CWWA 3EZQB 4N1LA 3YGSP 4UZ0A 2OF5A 3EZQA 3T6PA 2OF5H 1WXPA 3MOPK 3LQRA 4N1JA 2LWEA 3QF2A 4D8OA 2MPCA 4A2QA 4IZ7B 1C15A 1A1ZA 2A5YB 2KM6A 3MOPG 4M9ZA 3KATA 2N00A 4M9XA 1D2ZB 2A9IA 1E3YA 2N97A 3J63A 1WMGA 1D2ZA 4EWIA 4P4HI 3MOPA 2LS7A 1YGOA 2VGQA 4IZ5E 1NGRA 1WH4A 2P1HA 4IZAB 4P4HA 1E41A 1DDFA 3LQQA 4F42A 2N1FA 2O71A 4O9FA 4NQKA 2MB9A 2L6AA 1PN5A 2MS8A 2DBGA 2NSNA 2BBZA 2DBFA 3CL3A 4RHWE 4O7QA 4M9SA 4O9LA 4RHWA 1DGNA 2IB1A 1ICHA 2YQFA 3YGSC 3J6JA 2MN4A 4DWNA 2YVIA 2MS7A 2N83A 2YGSA 2B1WA 2G7RA 4JUPA 4E9MA 2YU0A 2N80A 1CY5A 4ZBWA 2XV9A 1UCPA 2DO9A 4LWDA 2L9MA 1Z6TA 2GF5A 4JQWA 4O6XA 2LWDA 4F44A 2DBDA 2N7ZA 4A2WA 2DBHA 2M5VA 2MJMA 3CRDA 1FADA 4I16A 4FH0A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2NAQ A;  2D96 A;  1A1W A;  2F1S A;  2BBR A;  2NZ7 A;  2HM2 Q;  2KN6 A;  1N3K A;  4QOB A;  4N1K A;  1CWW A;  3EZQ B;  4N1L A;  3YGS P;  4UZ0 A;  2OF5 A;  3EZQ A;  3T6P A;  2OF5 H;  1WXP A;  3MOP K;  3LQR A;  4N1J A;  3QF2 A;  2LWE A;  4D8O A;  2MPC A;  4A2Q A;  4IZ7 B;  1C15 A;  1A1Z A;  2A5Y B;  2KM6 A;  3MOP G;  4M9Z A;  3KAT A;  2N00 A;  4M9X A;  1D2Z B;  2A9I A;  1E3Y A;  2N97 A;  3J63 A;  1WMG A;  1D2Z A;  4EWI A;  4P4H I;  3MOP A;  2LS7 A;  1YGO A;  2VGQ A;  4IZ5 E;  1NGR A;  1WH4 A;  2P1H A;  4IZA B;  4P4H A;  1E41 A;  1DDF A;  3LQQ A;  4F42 A;  2N1F A;  2O71 A;  4O9F A;  4NQK A;  2MB9 A;  2L6A A;  1PN5 A;  2MS8 A;  2DBG A;  2NSN A;  2BBZ A;  2DBF A;  3CL3 A;  4RHW E;  4O7Q A;  4M9S A;  4O9L A;  4RHW A;  1DGN A;  2IB1 A;  1ICH A;  2YQF A;  3YGS C;  3J6J A;  2MN4 A;  4DWN A;  2YVI A;  2MS7 A;  2N83 A;  2YGS A;  2B1W A;  2G7R A;  4JUP A;  4E9M A;  2YU0 A;  2N80 A;  1CY5 A;  4ZBW A;  1UCP A;  2DO9 A;  4LWD A;  2L9M A;  1Z6T A;  2GF5 A;  4JQW A;  4O6X A;  2LWD A;  4F44 A;  2DBD A;  2N7Z A;  4A2W A;  2DBH A;  2M5V A;  3CRD A;  1FAD A;  4I16 A;  4FH0 A; 
#chains in the Genus database with same CATH topology
 2NAQ A;  2D96 A;  1A1W A;  2F1S A;  2BBR A;  2NZ7 A;  2HM2 Q;  2KN6 A;  1N3K A;  4QOB A;  4N1K A;  1CWW A;  3EZQ B;  4N1L A;  3YGS P;  4UZ0 A;  2OF5 A;  3EZQ A;  3T6P A;  2OF5 H;  1WXP A;  3MOP K;  3LQR A;  4N1J A;  2LWE A;  3QF2 A;  4D8O A;  2MPC A;  4A2Q A;  4IZ7 B;  1C15 A;  1A1Z A;  2A5Y B;  2KM6 A;  3MOP G;  4M9Z A;  3KAT A;  2N00 A;  4M9X A;  1D2Z B;  2A9I A;  1E3Y A;  2N97 A;  3J63 A;  1WMG A;  1D2Z A;  4EWI A;  4P4H I;  3MOP A;  2LS7 A;  1YGO A;  2VGQ A;  4IZ5 E;  1NGR A;  1WH4 A;  2P1H A;  4IZA B;  4P4H A;  1E41 A;  1DDF A;  3LQQ A;  4F42 A;  2N1F A;  2O71 A;  4O9F A;  4NQK A;  2MB9 A;  2L6A A;  1PN5 A;  2MS8 A;  2DBG A;  2NSN A;  2BBZ A;  2DBF A;  3CL3 A;  4RHW E;  4O7Q A;  4M9S A;  4O9L A;  4RHW A;  1DGN A;  2IB1 A;  1ICH A;  2YQF A;  3YGS C;  3J6J A;  2MN4 A;  4DWN A;  2YVI A;  2MS7 A;  2N83 A;  2YGS A;  2B1W A;  2G7R A;  4JUP A;  4E9M A;  2YU0 A;  2N80 A;  1CY5 A;  4ZBW A;  2XV9 A;  1UCP A;  2DO9 A;  4LWD A;  2L9M A;  1Z6T A;  2GF5 A;  4JQW A;  4O6X A;  2LWD A;  4F44 A;  2DBD A;  2N7Z A;  4A2W A;  2DBH A;  2M5V A;  2MJM A;  3CRD A;  1FAD A;  4I16 A;  4FH0 A; 
#chains in the Genus database with same CATH homology
 2NAQ A;  2D96 A;  1A1W A;  2F1S A;  2BBR A;  2NZ7 A;  2HM2 Q;  2KN6 A;  1N3K A;  4QOB A;  4N1K A;  1CWW A;  3EZQ B;  4N1L A;  3YGS P;  4UZ0 A;  2OF5 A;  3EZQ A;  3T6P A;  2OF5 H;  1WXP A;  3MOP K;  3LQR A;  4N1J A;  2LWE A;  3QF2 A;  4D8O A;  2MPC A;  4A2Q A;  4IZ7 B;  1C15 A;  1A1Z A;  2A5Y B;  2KM6 A;  3MOP G;  4M9Z A;  3KAT A;  2N00 A;  4M9X A;  1D2Z B;  2A9I A;  1E3Y A;  2N97 A;  3J63 A;  1WMG A;  1D2Z A;  4EWI A;  4P4H I;  3MOP A;  2LS7 A;  1YGO A;  2VGQ A;  4IZ5 E;  1NGR A;  1WH4 A;  2P1H A;  4IZA B;  4P4H A;  1E41 A;  1DDF A;  3LQQ A;  4F42 A;  2N1F A;  2O71 A;  4O9F A;  4NQK A;  2MB9 A;  2L6A A;  1PN5 A;  2MS8 A;  2DBG A;  2NSN A;  2BBZ A;  2DBF A;  3CL3 A;  4RHW E;  4O7Q A;  4M9S A;  4O9L A;  4RHW A;  1DGN A;  2IB1 A;  1ICH A;  2YQF A;  3YGS C;  3J6J A;  2MN4 A;  4DWN A;  2YVI A;  2MS7 A;  2N83 A;  2YGS A;  2B1W A;  2G7R A;  4JUP A;  4E9M A;  2YU0 A;  2N80 A;  1CY5 A;  4ZBW A;  2XV9 A;  1UCP A;  2DO9 A;  4LWD A;  2L9M A;  1Z6T A;  2GF5 A;  4JQW A;  4O6X A;  2LWD A;  4F44 A;  2DBD A;  2N7Z A;  4A2W A;  2DBH A;  2M5V A;  2MJM A;  3CRD A;  1FAD A;  4I16 A;  4FH0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2A9IA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN